专利检索_ .使分子氧还原成两分子水的一对供体氧化专利检索_ .使分子氧还原成两分子水的一对供体氧化专利检索查询

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序号	专利名	申请号	申请日	公开（公告）号	公开（公告）日	发明人
61	OMEGA3 UNSATURATED FATTY ACID ENZYME AND METHOD FOR PRODUCING EICOSAPENTAENOIC ACID	US14915178	2014-08-26	US20160208297A1	2016-07-21	Jun OGAWA; Eiji SAKURADANI; Akinori ANDO; Sakayu SHIMIZU; Masataka HARATA; Shigeru HIRAMOTO
Provided is an ω3 desaturase having a high enzymatic activity even at normal temperature. A polypeptide consisting of an amino acid sequence having an identity of 80% or more with the amino acid sequence represented by SEQ ID NO: 2 and having ω3 desaturation activity, and a gene therefor.
62	Desaturases of a green microalga and uses thereof	US14804638	2015-07-21	US09315837B2	2016-04-19	Iskandarov Umidjon; Inna Khozin Goldberg; Zvi Hacohen
Isolated proteins which are at least partially encoded by polynucleotide sequences encoding novel desaturases are provided together with a composition which includes these isolated proteins. A transgenic plant, a transgenic alga, or a transgenic seed transformed by the polynucleotides encoding proteins which are at least partially encoded by novel desaturases are also provided. The invention also includes a process for making a very long-chain polyunsaturated fatty acid in a transformed cell, a transgenic alga, or a transgenic plant expressing the isolated protein or proteins which are at least partially encoded by the polynucleotide sequences encoding novel Δ5, Δ6, or Δ12 desaturases.
63	DELTA-5 DESATURASES AND THEIR USE IN MAKING POLYUNSATURATED FATTY ACIDS	US14594576	2015-01-12	US20150175977A1	2015-06-25	Howard G. DAMUDE; Quinn Qun ZHU
Isolated nucleic acid fragments and recombinant constructs comprising such fragments encoding delta-5 desaturases along with a method of making long-chain polyunsaturated fatty acids (PUFAs) using these delta-5 desaturases in plants are disclosed.
64	Microorganisms and methods for producing unsaturated fatty acids	US13326211	2011-12-14	US08790901B2	2014-07-29	Subhayu Basu; Gaozhong Shen; Brett Boghigian; David Young; David Berry; Geoffrey von Maltzahn
Methods of producing an unsaturated free fatty acid comprising at least 18 carbon atoms are provided. In some embodiments, the methods comprise culturing an engineered microorganism in a culture medium, wherein the engineered microorganism comprises at least one recombinant enzyme selected from acyl-lipid desaturase delta-9 (EC:1.14.19.1), acyl-lipid desaturase delta-12 (EC:1.14.19.6), acyl-lipid desaturase delta-15 (EC:1.14.19.-), and thioesterase (EC:3.1.2.14). Engineered microorganisms comprising at least one of those recombinant enzymes are also provided. The methods and organisms can be used to produce at least one free fatty acid selected from oleic acid, linoleic acid and α-linolenic acid.
65	Algal desaturases	US13888310	2013-05-06	US08785610B2	2014-07-22	Oliver Kilian; Bertrand Vick
Provided herein are exemplary isolated nucleotide sequences encoding polypeptides having desaturase activity, which utilize fatty acids as substrates.
66	ALGAL DESATURASES	US13888310	2013-05-06	US20130281683A1	2013-10-24	Oliver Kilian; Bertrand Vick
Provided herein are exemplary isolated nucleotide sequences encoding polypeptides having desaturase activity, which utilize fatty acids as substrates.
67	ALGAL DESATURASES	US13458914	2012-04-27	US20120277417A1	2012-11-01	Oliver Kilian; Bertrand Vick
Provided herein are exemplary isolated nucleotide sequences encoding polypeptides having desaturase activity, which utilize fatty acids as substrates.
68	다중불포화지방산 생산용 미세조류 배양 배지 조성물 및 방법	KR1020170090790	2017-07-18	KR101818887B1	2018-01-16	정해진; 장세현; 임안숙; 권지은
본원은미세조류에서다중불포화지방산생산능향상을위한,,, 또는로부터선택된하나이상의먹이종을포함하는미세조류배양배지조성물및 방법을개시한다. 본원에따른조성물및 방법은미세조류에서오메가-3 지방산등의다중불포화지방산를고농도로생산할수 있다.
69	PUFA 생산을 위한 물질 및 방법, 및 PUFA-함유 조성물	KR1020177016137	2015-11-13	KR1020170099884A	2017-09-01	젱어,토랄프; 마티,로랑; 쿤체,이레네; 하르텔,하이코아.; 브레머,스티븐; 브리질,스티븐; 바우어,예르크; 브린텐,패트리시아; 스팀네,스텐; 린드베르크일마즈,제니; 맥엘버,존; 라인,디트리히; 안드레,칼
좌측및 우측경계요소및 표적유전자에작동가능하게연결된, 프로모터, 및그의하류의종결인자를포함하는적어도 1개의발현카세트를포함하는, 식물에서표적유전자의발현을위한 T-DNA이며, 여기서좌측에서우측경계요소까지측정되고표적유전자를포함한 T-DNA의길이는적어도 30000 bp의길이를갖는다.
70	고 올레산 오일	KR1020147033143	2013-04-24	KR1020150023296A	2015-03-05	우드,크레이그,크리스토퍼; 리우,청; 주,쉐-롱; 그린,앨런; 싱,수린더팔; 카오,시지앙
본 발명은 높은 수준, 예를 들어 90 내지 95 중량%의 올레산을 갖는 추출된 지질에 관한 것이다. 본 발명은 또한 상기 지질의 생산에 사용될 수 있는 유전자 변형된 식물, 특히 잇꽃과 같은 유지종자를 제공한다. 더욱 또한, 상기 지질의 생산에 사용될 수 있는 식물의 유전형질분석 및 선택 방법을 제공한다.
71	파이토프토라 유래 델타-6 불포화효소 유전자로 형질전환된 들깨 및 이의 제조방법	KR1020120122494	2012-10-31	KR1020140056779A	2014-05-12	이경렬; 김경환; 김현욱; 김정봉; 김종범; 노경희; 김순희
The present invention relates to a manufacturing method of transgenic perilla producing gamma-linolenic acid or stearidonic acid which comprises a step of transforming perilla with a recombinant vector comprising delta-6 desaturase gene derived from Phytophthora citrophthora consisting of a nucleotide sequence of SEQ ID NO: 1 and transgenic perilla manufactured thereby.
72	DELTA-5 DESATURASE AND ITS USE IN MAKING POLYUNSATURATED FATTY ACIDS	PCT/US2007012233	2007-05-17	WO2007136877A2	2007-11-29	DAMUDE HOWARD G; ZHU QUINN QUN
Isolated nucleic acid fragments and recombinant constructs comprising such fragments encoding delta-5 desaturase along with a method of making long chain polyunsaturated fatty acids (PUFAs) using this delta-5 desaturase in plants and oleaginous yeast are disclosed.
73	METHOD OF PRODUCING POLYUNSATURATED FATTY ACID	US15614896	2017-06-06	US20180346944A1	2018-12-06	Lok Man So; Man Chak Tse; Kai Kin Chi; Yuen Chong Kong; Sin Yu Yeung
A method of producing a polyunsaturated fatty acid in a transgenic bacterium, includes: introducing a recombinant plasmid into a bacteria cell to obtain the transgenic bacterium, wherein the recombinant plasmid comprises a polynucleotide encoding one or more elongase and one or more desaturase; incubating the transgenic bacterium in a medium containing a fatty acid substrate; harvesting the transgenic bacterium, and extracting the polyunsaturated fatty acid from the transgenic bacterium. A method of converting linoleic acid to arachidonic acid and a cassette and recombinant plasmid comprising nucleic acid sequences for the above methods are also provided.
74	Enzymes, enzyme components and uses thereof	US15864798	2018-01-08	US10119126B2	2018-11-06	Laurent Marty; Toralf Senger
The invention provides nucleic acid molecules which encodes a novel fatty acid desaturase, KCS, KCR and/or LACS from Thraustochytrium aureum and Sphaeroforma arctica. The invention also provides recombinant expression vectors containing the nucleic acid molecules, host cells into which the expression vectors have been introduced, and methods for large-scale production of long chain polyunsaturated fatty acids (LCPUFAs), e.g., ARA, EPA and DHA and for screening for delta-4 desaturases.
75	STABILISING FATTY ACID COMPOSITIONS	US15525463	2015-11-13	US20180291389A1	2018-10-11	Toralf Senger; Heiko A. Haertel
Assay method, comprising providing a plant capable of expressing a delta-12 desaturase, wherein said delta-12 desaturase has at least 50% total amino acid sequence identity to at least one of the sequences SEQ ID NO. 328 to 336, and/or at least 59% total amino acid sequence similarity to at least one of the sequences SEQ ID NO. 328 to 336, and wherein the plant is also capable of expressing at least one or more enzymes of unsaturated fatty acid metabolism, of which enzymes at least one is capable of using linoleic acid as a substrate, and of which enzymes at least one is supposedly connected to a plant metabolic property, growing the plant, and measuring said plant metabolic property for said plant.
76	Enzymes and methods for producing omega-3 fatty acids	US15644635	2017-07-07	US09994792B2	2018-06-12	James Robertson Petrie; Anne Maree Mackenzie; Qing Liu; Pushkar Shrestha; Peter David Nichols; Susan Irene Ellis Blackburn; Maged Peter Mansour; Stanley Suresh Robert; Dion Matthew Frederick Frampton; Xue-Rong Zhou; Surinder Pal Singh; Craig Christopher Wood
The present invention relates generally to the field of recombinant fatty acid synthesis, particularly in transgenic plants. The application describes genes involved in fatty acid synthesis and provides methods and vectors for the manipulation of fatty acid composition of plant oils. In particular, the invention provides constructs for achieving the integration of multiple heterologous genes involved in fatty acid synthesis into the plant genome, such that the resulting plants produce altered levels of polyunsaturated fatty acids. Also described are methods for enhancing the expression of fatty acid biosynthesis enzymes by co-expressing a silencing suppressor within the plant storage organ.
77	Enzymes and methods for producing ω-3 fatty acids	US15661673	2017-07-27	US09976107B2	2018-05-22	James Robertson Petrie; Anne Maree Mackenzie; Qing Liu; Pushkar Shrestha; Peter David Nichols; Susan Irene Ellis Blackburn; Maged Peter Mansour; Stanley Suresh Robert; Dion Matthew Frederick Frampton; Xue-Rong Zhou; Surinder Pal Singh; Craig Christopher Wood
The present invention relates to methods of synthesizing long-chain polyunsaturated fatty acids, especially eicosapentaenoic acid, docosapentaenoic acid and docosahexaenoic acid, in recombinant cells such as yeast or plant cells. Also provided are recombinant cells or plants which produce long-chain polyunsaturated fatty acids. Furthermore, the present invention relates to a group of new enzymes which possess desaturase or elongase activity that can be used in methods of synthesizing long-chain polyunsaturated fatty acids. In particular, the present invention provides ω3 destaurases, Δ5 elongases and Δ6 desaturases with novel activities. Also provided are methods and DNA constructs for transiently and/or stably transforming cells, particularly plant cells, with multiple genes.
78	Materials and Methods for Increasing the Tocopherol Content in Seed Oil	US15525768	2015-11-13	US20170335338A1	2017-11-23	Carl Andre
The present invention relates generally to the field of molecular biology and concerns increasing the tocopherol content of a plant relative to a control plant, comprising expressing in a plant at least one polynucleotide encoding a delta-12-desaturase, at least one polynucleotide encoding a delta-6-desaturase, at least one polynucleotide encoding a delta-6-elongase, and at least one polynucleotide encoding a delta-5-desaturase. The present invention also relates to methods for the manufacture of oil, fatty acid- or lipids-containing compositions, and to such oils and lipids as such.
79	Soybean seed and oil compositions and methods of making same	US15267649	2016-09-16	US09816100B2	2017-11-14	Nicholas William Wagner
Soybean oil compositions with unique fatty acid profiles are disclosed. These oils can be derived by the suppression of endogenous soybean FAD2 and FAD3 genes and the expression of a stearoyl acyl ACP thioesterase. Soybean plants and seeds comprising these oils are also disclosed.
80	PREPARATION OF 7-DEHYDROCHOLESTEROL AND/OR THE BIOSYNTHETIC INTERMEDIATES AND/OR SECONDARY PRODUCTS THEREOF IN TRANSGENIC ORGANISMS	US15412724	2017-01-23	US20170198328A1	2017-07-13	Christine Lang; Markus Veen
The present invention relates to a method for preparing 7-dehydrocholesterol and/or the biosynthetic intermediates and/or secondary products thereof by culturing organisms, in particular yeasts. Furthermore, the invention relates to the preparation of the nucleic acid constructs required for preparing the genetically modified organisms and to said genetically modified organisms, in particular yeasts, themselves.

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