| 序号 | 专利名 | 申请号 | 申请日 | 公开（公告）号 | 公开（公告）日 | 发明人 |
|---|---|---|---|---|---|---|
| 441 | Channel-less separation of biological particles on the bio-electronic chips by dielectrophoresis | JP2000529896 | 1999-01-26 | JP2002502047A | 2002-01-22 | エドワード・エル・シェルドン・ザ・サード; ジェイムズ・ピー・オコーネル; ジン・チェン; レイ・ウー |
| (57)【要約】 本発明は、その全てを単一のバイオエレクトロニック・チップ上で行い得る、誘電泳動、分離した細胞のＤＣ高電圧−パルス電気溶解、細胞ライゼートのごとき粗製混合物からの目的のコンポーネントの分離、および／またはかかるライゼートの酵素反応によって細胞粒子のチャネルレス分離を行うためのデバイスおよび方法を含む。 本発明の好ましい態様は、プリント回路基板（１４）上の微細加工シリコンチップ（１２）および該チップ（１２）にマウントされたフローセル（１６）を含むカートリッジ（１０）よりなる。 該カートリッジ（１０）には、当該カートリッジ（１０）を電子コントローラに電子的に接続する出力ピン（２２）も含まれる。 該チップ（１２）には、好ましくはいずれかの電極とフローチャンバーに導入された試料との間の直接的な接触を防ぐ保護浸透層で被覆された複数の円形微小電極（２４）が含まれる。 該浸透層は、フィールド最小における細胞付着を減少することも助け、特異的な細胞捕捉用の特異的な抗体の固定化を可能とする。 種々の細胞混合物からの特異的な細胞を、該チップ上で分離し、溶解し、酵素消化した。 | ||||||
| 442 | Apparatus for separating a mixture | JP51813693 | 1993-04-15 | JP3182151B2 | 2001-07-03 | ベッツ，ウォルター・バーナード; ホークス，ジェレミー・ジョン |
| 443 | Fine chemical device having liquid separating structure | JP32040799 | 1999-11-11 | JP2001137693A | 2001-05-22 | ANAZAWA TAKANORI; TERAMAE ATSUSHI |
| PROBLEM TO BE SOLVED: To provide a fine chemical device capable of continuously performing extraction or oil-water separation by bringing a fine quantity of mutually immiscible liquids into contact with each other and separating. SOLUTION: A capillary flow passage is formed in the fine chemical device, the inside surface in the down stream end of the flow passage has a low contact angle part having ≤25° contact angle with water and a high contact angle part having ≥10° higher contact angle with water than that of the low contact angle part, a liquid separating chamber having a cross-sectional area 2-1,000 times of that of the capillary flow passage is formed and respective discharge passages from the low contact angle part and the high contact angel part are formed in the liquid separating chamber. COPYRIGHT: (C)2001,JPO | ||||||
| 444 | Sampel dispensing device | JP28697299 | 1999-10-07 | JP2001104821A | 2001-04-17 | NAGAOKA YOSHIHIRO; YAMAKAWA HIRONOBU; YAMAZAKI ISAO |
| PROBLEM TO BE SOLVED: To provide a sample dispensing device with which high-accuracy sample dispensing is made possible and electric power consumption may be reduced even in the case of a microanalysis as the sample dispensing device constituted to migrate the respective components of the sample in which the plural components coexist in a migration liquid and to dispense the components of the sample separated by the migration. SOLUTION: The sample dispensing device has a sample migration section 2 for causing the migration of the respective components in the sample in the migration liquid made to flow continuously in a specified direction and has a lower magnet 230 as a magnetic field impressing means. A magnetic field is impressed to the sample by the magnetic field impressing means so as to intersect with the flow direction of the migration liquid within a migration chamber 240 in the sample migration section 2, by which the migration of the respective sample components is induced. The migration for separating and dispensing the respective components from the sample in which the plural components coexist by magnetic force as described above is obtd. and therefore the problem of the Joule heat by using an electric field like in the prior art is effectively solved and the high-accuracy dispensing is made possible even in the case of the microanalysis and the electric power consumption during the separating and dispensing operation may be reduced. | ||||||
| 445 | Method of analysis / separation | JP51339298 | 1997-09-10 | JP2001502226A | 2001-02-20 | エイガー，コーリン，デニス; サフォード，ニコラス，アーチバルド; デイムス，アンドリュー，ニコラス; パーヴィス，ダンカン，ロス |
| (57)【要約】 進行波分離の使用により、粒子はその誘電電気泳動特性及び電気回転特性に基づいて分離される。 進行波分離において、粒子は入口（１８）に位置する出発点から出口（１６，２０）に位置する少なくとも２つの目的地へ向けて流れ、かつ一方または他方の出口へ偏向され、同偏向は流動方向に概して延びる複数の電極からなるアレイへ印加された進行波電界によって前記の粒子の特性に基づいて行われる。 | ||||||
| 446 | Device for electrostatically flocculating, adhering and separating impurity in liquid | JP16546499 | 1999-06-11 | JP2000354789A | 2000-12-26 | INOUE MASAHITO; NAKAYAMA TOSHIHIKO |
| PROBLEM TO BE SOLVED: To continuously treat liquid to be treated by impressing voltage between a vessel and a drum which is rotated with slow speed and immersed in the liquid to be treated with which the vessel is filled, adhering particulates included in the liquid to be treated to the drum while flocculating the particulates and removing the particulates at a separate place from the liquid to be treated. SOLUTION: A cylindrical rotary drum electrode 1 is disposed in a vessel of a vessel grounded electrode 2, which has a semicylindrical shape and a larger inner diameter than the drum electrode 1. The vessel grounded electrode 2 and the rotary drum electrode 1 are faced each other to form passage 3. A voltage having such a height is impressed between both electrode 1 and 2 in accordance with a characteristic of particulates of impurities in a liquid of a liquid 8 to be treated that zeta potential of the particulates of the impurities in the liquid can be reduced or vanished and the particulates of the impurities in the liquid can be adhered to the electrode 1. The rotary drum electrode 1 is rotated together with impressing the voltage and the particulates included in the liquid 8 to be treated are adhered to and deposited on the rotary drum electrode 1 while being flocculated. The adhered and deposited impurities 9 in the liquid are removed at a separate place from the liquid 8 to be treated. COPYRIGHT: (C)2000,JPO | ||||||
| 447 | Electrostatic filtration device | JP22550697 | 1997-07-16 | JP3084475B2 | 2000-09-04 | 健吉 徳本 |
| 448 | Wet type image forming device and method | JP35864198 | 1998-12-17 | JP2000181236A | 2000-06-30 | SASAKI TSUTOMU; KUROTORI TSUNEO |
| PROBLEM TO BE SOLVED: To provide a wet type image forming device and a wet type image forming method by which a carrier liquid component can be recycled by being separately extracted. SOLUTION: Eliminated and recovered liquid developer is passed through a continuous foaming body 41 being the liquid diffusion suppressing member disposed between electrodes 43 and 44 where an electric field is generated and provided with pores. Then, the electrodes 43 and 44 and the foaming body 41 are disposed by being inclined so that the terminating end of the electrode 43 on a non-electrodeposition side is positioned more downward than the terminating end of the electrode 44 on an electrodeposition side at the terminating end parts of the electrodes being the exit of carrier liquid. By this constitution, since the carrier liquid can be made to flow along the terminating end part of the electrode 43, the solid part of toner is prevented from being mixed in the vicinity of the exit of the carrier liquid. Besides, the pure carrier liquid 24 can be extracted from the electrode 43 by constituting so that the terminating end part of the electrode 43 is made to project from that of the electrode 44. | ||||||
| 449 | Sorting method and apparatus using a dielectric electrophoresis and field flow fractionation | JP52789697 | 1997-01-31 | JP2000505545A | 2000-05-09 | ガスコイン，ピーター・アール・シー; ファン，イン; ベッカー，フレデリック・エフ; ワン，シャオ―ボ |
| (57)【要約】 本願発明は、物質の分離、特徴付け、操作のための新規装置と新規方法とに関するものである。 特に、本発明は、そのような物質を識別及び分離するために、粒状物質および溶解物質の周波数依存性の誘電および導電特性と、懸濁輸送培地の特性の使用を組み合わせている。 本装置は、細胞を導入し、取り出すための、少なくとも一の電極素子と少なくとも一の入口ポートと出口ポートとを備えた室を含む。 流体の流れにより室を通って運ばれた物質は、その後、エネルギーを与えられた電極により引き起こされる誘電電気泳動（DEP）力によって流体内で分離される。 流体の中での分離に続いて、物質は、速度プロフィールに応じた速度で室を通って移動する。 物質が室を通って通過した後、物質は特徴的な位置で室の反対側の端から出ていく。 本発明の方法は、調査、状態の診断、治療目的で物質を識別及び分離するための装置を使用することを含む。 そのような方法の例は、癌細胞の正常細胞からの分離、正常赤血球からの寄生された赤血球の分離、核酸の分離などといった、細胞混合物の分離を含む。 | ||||||
| 450 | Filter and apparatus for removing foreign substance employing same | JP30577998 | 1998-10-27 | JP2000126518A | 2000-05-09 | TOMIOKA KOICHI |
| PROBLEM TO BE SOLVED: To make clogging of a filter, which removes foreign substances of a working fluid of a hydraulic actuator, hardly occur and to efficiently remove fine foreign substances by the filter. SOLUTION: A filter layer constituted of circularly formed primary filter layers 201, 201' and secondary filter layers 202, 202' is arranged symmetrically on a core material 203 and the outer periphery 206 of the respective primary filter layers 201, 201' and secondary filter layers 202, 202' is firmly closed. The primary filter layers 201, 201' are formed in the upstream side in relation to the flow of a fluid and adsorb and remove solid foreign substances mixed in the fluid by static electricity generated by friction with the fluid and the secondary filter layers 202, 202' are formed in the downstream side of the primary filter layers 201, 201' in the fluid flow direction and are made of materials (nonwoven fabrics of polyester long fibers) different from those (wool presses felt) of the primary filter layers. COPYRIGHT: (C)2000,JPO | ||||||
| 451 | Removal of particulate matter from silicon-containing liquid compound | JP29604499 | 1999-10-19 | JP2000119396A | 2000-04-25 | HALM ROLAND LEE; KEITH QUENTIN HAYES |
| PROBLEM TO BE SOLVED: To provide a method for removing particulate matter from a silicon- containing liquid compound. SOLUTION: This removing method comprises bringing a suspension comprising a non-conductive silicon-containing liquid compound and particulate matter having a dielectric constant different from that of the non-conductive silicon- containing liquid compound, into contact with a non-conductive filler substrate 8 in an electric field. Especially, the method is useful for the removal of the suspended particulate matter having 0.01-100 μm particle diameter from a silicon fluid. COPYRIGHT: (C)2000,JPO | ||||||
| 452 | Characterized by dielectrophoresis of microorganisms, other particles | JP50022691 | 1990-11-27 | JP2987201B2 | 1999-12-06 | BETSUTSU UORUTAA BAANAADO; HOOKUSU JEREMII JON |
| 453 | Solid-liquid separation of particulates mixed liquid and device therefor in silicon wafer production process | JP5810898 | 1998-03-10 | JPH11253838A | 1999-09-21 | MASAKI KAZUO; MOTOYAMA YOSHINARI |
| PROBLEM TO BE SOLVED: To efficiently separate particulates using electric energy from a particulates mixed liquid discharged from a silicon wafer producing device to reutilize. SOLUTION: In a vessel 20 receiving the particulates mixed liquid 3' from the silicon wafer production process, the particulates 32 in the particulates mixed liquid 3' are attracted to an electrode 22 side having a large electric field density by forming a high density electric field between electrodes 21 and 22 arranged at a desired interval and a dielectric film 28 is moved along the front surface of the electrode 22 having the large electric field density. As a result, the particulates 32 are stuck to the dielectric film 28 and the dielectric film 28 is discharged outside the vessel 20 to remove the particulates 32 stuck to the dielectric film 28. COPYRIGHT: (C)1999,JPO | ||||||
| 454 | Device and method for removing suspended matter | JP30048297 | 1997-10-31 | JPH11128773A | 1999-05-18 | NAWATA HIDEO |
| PROBLEM TO BE SOLVED: To carry out the dehydration easily, and improve the removing efficiency of suspended particles. SOLUTION: Suspended matters contained in wastewater are attracted removed by utilizing the static force generated by charged particles 30, and suspended matters and a water content adhered on the charged particles 30 are dehydrated and separated on a screen belt 33 in the constitution of a device. The upstream side of a screen belt 33 on which the charged particles 30 with suspended matters adhered on is formed into a low speed zone 34 blowing air at low speed, while its downstream side is set to be a high speed zone 35 blowing air at high speed, and a water recovery tank 36 is set on the lower section of the low speed zone 34, while a suspended matter recovery tank 37 is set on the lower section of the high speed zone 35. COPYRIGHT: (C)1999,JPO | ||||||
| 455 | Semiconductor method and apparatus for ultra-low number of counts the number of particles at the time of manufacture | JP50739296 | 1995-08-02 | JPH10505537A | 1998-06-02 | アベイ ケー ブシャン; ラジヴ ブシャン; スラジ プリ; ラジャ マヒンドゥラ |
| (57)【要約】 本発明は、汚染物を導入することなくウェーハから化学薬品および粒子をすすぎ洗いするためのウェーハすすぎ洗い装置に関する。 この装置は、ウェット・ベンチのところでのすすぎ洗い中に使用する水およびガスを濾過することによってウェーハ上の粒子のカウント数を低減する。 この装置は、すすぎ洗いユニットと、局限水フィルタ・バンクと、局限ガス濾過装置と、Ｈ 2 Ｏ 2注入ユニットと、補助化学薬品注入ユニットと、他の構成要素を作動させるコントローラとを包含する。 水フィルタ・バンクは、多段濾過装置を提供し、水の圧力に実質的な低下を生じさせることなく粒子を除去する。 Ｈ 2 Ｏ 2注入ユニットは、Ｈ 2 Ｏ 2の局部的な源を提供し、フィルタおよびすすぎ洗い機を洗浄すると共にすすぎ洗い中のウェーハ上での自然酸化物の生成を制御する機構を提供する。 補助化学薬品注入ユニットはすすぎ洗いユニットに化学添加物を与えてウェーハ洗浄工程の効率を高める。 ガス濾過装置は、すすぎ洗いユニットおよび注入ユニットに清浄ガスを与える。 清浄ガスは各注入ユニット内の化学薬品上ならびにすすぎ洗い機内の水の上に清浄雰囲気を与える。 | ||||||
| 456 | Electrostatic oil filter | JP11800296 | 1996-05-13 | JPH09303127A | 1997-11-25 | KURASHIGE TADAHIRO; KUWABARA RYUJI |
| PROBLEM TO BE SOLVED: To improve capturing efficiency in a positive plate side by providing a plurality of charged particle capturing elements arranged in a casing, and constituting each element so as to have a holding space of oil constituted by a volute non-conductive partition member and a pair of electrodes arranged in both ends thereof. SOLUTION: An electrostatic oil filter suitably used in an automobile is provided with a casing 10 and a plurality of charge particle capturing elements 12 arranged in the inside thereof. The element 12 has a pair of positive/negative plates 28, 30 arranged in an upper/lower end of a non-conductive partitioning member 26, it is constituted by a circular part in the center and a volute member arranged in a periphery thereof, in the upper/lower of these members, the positive plate 28 and a porous insulating material are arranged as a pair, the negative plate 30 is set up in the outermost surface part, a volute oil holding space 34, constituted by these members, is provided. In this way, a holding time of oil in the holding space 34 is lengthened, capturing efficiency of carbon particles is enhanced. COPYRIGHT: (C)1997,JPO | ||||||
| 457 | Adhesion control possible, ultra-miniaturized surface structure | JP51709295 | 1994-12-23 | JPH09511434A | 1997-11-18 | ヴァーグナァ，ベルント; ハーゲドルン，ロルフ; フール，ギュンター; フォイグト，アンドレアス; ミュラー，トルステン; リゼック，トーマス |
| (57)【要約】 弾力的又は剛性の材料への粒子の吸着或いは付着を回避し、又は選択的にこれを高めるために、(マイクロメートル領域以下に)極度に小型化された平坦な電極ストライプ（22;42、44;52）が、遊走又は静止する電気的表面波が発生するように、高周波のパルスシーケンスで負荷可能である表面（21;41、51）に取り付けられ、電極それ自体は、電気的に絶縁性の、又はその生物適合性が吟味された絶縁材料（23;43、45;53）を使用して組み合わされ、これによって部分的に又は全面的に被覆される。 電気的制御の方法は、電極を被覆する表面層の特性との関連で、使用される塩基性材料とは十分に無関係に表面の付着特性を規定する。 粒子の運動は、無理のない影響を受ける。 初めて高生理培養液中の粒子に影響を与えることが可能になる。 | ||||||
| 458 | Treatment of aqueous fluid and device therefor | JP9164096 | 1996-03-08 | JPH09239372A | 1997-09-16 | RI MEISEI |
| PROBLEM TO BE SOLVED: To continuously treat an aq. fluid by utilizing the polarization of an electric field to solidify the impurities in the fluid and facilitating the separation of the impurities from the fluid in a method and device for continuously treating the fluid. SOLUTION: A water outlet 13 and a water inlet 12 are arranged on the top and bottom of a process tank 1, ≥3 conductive plates 4, wherein a substantially closed, S-shaped upward one-way passage is formed, are provided in the internal space. The conductive plate is made of a conductive material having 1.59-3000μωm resistivity, at least two of the conductive plates are connected respectively to a positive power source and a negative power source and act as an anode 2 and a cathode 3. A water to be treated is introduced into the tank from the inlet, passed upward through the one-way passage and discharged from the tank through the outlet. A voltage is applied to the cathode and anode to generate 0.5mV/cm to 1000V/cm electric field in the aq. fluid in the passage, hence the impurities in the fluid are polarized and solidified, and the solidified impurities are removed. COPYRIGHT: (C)1997,JPO | ||||||
| 459 | Electrostatic oil purifier | JP3284296 | 1996-01-25 | JPH09201549A | 1997-08-05 | NISHI KAZUO |
| PROBLEM TO BE SOLVED: To make ionized impurities efficiently adsorbed by forming numbers of holes in both electrode plates, forming edge parts over entire electrode plates, and applying voltage. SOLUTION: In an electrostatic oil purifier 1, a large number of paired electrode plates 3, 4 are installed to be suspended at intervals in a housing 2, a supply port 5 for raw oil is formed in the lower part of the housing 2, and an outlet 6 is formed in the upper part. Numbers of holes 7, 8 are formed in the plates 3, 4 so that numbers of edge parts are formed over the entire plates 3, 4. When high direct current voltage is applied to the plate 3, each plate 3, 4 with their peripheral edge parts 3a, 4a, an electric field (e) is formed also in the edge parts of the holes 7, B which are formed over the entire plates 3, 4. When oil is introduced from the lower part of the housing 2 by a pump P, contained impurities are ionized and adsorbed by the electric field (e) formed over the entire electrode plates, and the oil, after being purified, is returned to a tank A. COPYRIGHT: (C)1997,JPO | ||||||
| 460 | Separation device according to the die electro Hori Thich | JP52185194 | 1994-03-31 | JPH08508205A | 1996-09-03 | ペシグ，ロナルド; マルクス，ジェラルダス・ヘンドリクス |
| (57)【要約】 本発明は、細胞質の分離に特に有効な分離装置に関する。 この分離装置は、ダイエレクトロホリティク（ＤＥＰ）として知られる現象を利用する。 ＤＥＰ力は、媒体中に懸濁される粒子に生じる。 粒子は、交番する電場において力を受ける。 この力は、とりわけ保持媒体と粒子と電場の周波数の電気的特性に比例する。 本発明の分離装置は、チャンバ（１０）と、このチャンバ内に配置された複数の電極（１２）とを含む。 電極に確立される電場が、粒子の一部を他の粒子より大きな作用力に曝して、これら粒子が前記チャンバ内に拘束されるようにする。 拘束されない粒子は、チャンバに圧送されることが望ましい保持媒体によりチャンバから除去される。 チャンバの出口に弁（１０１、２０２）が設けられる。 本発明は、２つの異なる粒子を連続的に分離することができる。 | ||||||
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