序号 | 专利名 | 申请号 | 申请日 | 公开(公告)号 | 公开(公告)日 | 发明人 |
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101 | Chiral phospholanes via chiral 1, 4-diol cyclic sulfates | US222750 | 1994-04-04 | US5386061A | 1995-01-31 | Mark J. Burk |
This invention relates to novel chiral 1,4-diol cyclic sulfates and their use as precursors in the preparation of chiral phospholane ligands, and chiral complexes useful as catalysts for carrying out enantioselective reactions. | ||||||
102 | Ruthenium-catalyzed production of cyclic sulfates | US712199 | 1991-06-07 | US5321143A | 1994-06-14 | K. Barry Sharpless; Yun Gao |
A ruthenium catalyzed method to synthesize cyclic sulfate compounds from the corresponding cyclic sulfites, and the cyclic sulfate reaction products obtained by this method. These cyclic sulfates further react with selected nucleophiles to give various substituted products. The method is an efficient means for the synthesis of chiral building blocks from tartaric acid enantiomers in high yields using an overall two-stage, one-pot reaction procedure. The chiral compounds can be transformed by nucleophilic reactions into chiral building blocks useful for the synthesis of natural biologically active products, such as antibiotics and pheromones. | ||||||
103 | Protected formylpentanediols, hydroxymethylpentanediols, process for their preparation and intermediates | US969632 | 1992-10-30 | US5274157A | 1993-12-28 | Heinz Moser |
Compounds of the formula Ib ##STR1## in which R.sub.1 and R.sub.2 independently of one another are linear or branched C.sub.1 -C.sub.12 alkyl, cycloalkyl having 5 to 8 ring carbon atoms, phenylalkyl having 1 to 4 C atoms in the alkylene group, the cyclic radicals being unsubstituted or substituted by C.sub.1 -C.sub.4 alkyl or C.sub.1 -C.sub.4 alkoxy, or R.sub.1 and R.sub.2 independently of one another are --SiR.sub.4 R.sub.5 R.sub.6 in which R.sub.4, R.sub.5 and R.sub.6 independently of one another are C.sub.1 -C.sub.12 alkyl, phenyl, benzyl, or phenyl or benzyl, each of which is substituted by C.sub.1 -C.sub.4 alkyl or C.sub.1 -C.sub.4 alkoxy, and R.sub.3 is a bridging member which, together with the radical --OCH--CH.sub.2 --CHO-- to which it is bonded, forms a 6- to 8-membered ring. These compounds are valuable intermediates for the preparation of carbacyclic nucleosides of the natural and unnatural series and of the racemates. | ||||||
104 | Electrocatalytic oxidation method for the production of cyclic sulfates and sulfamidates | US717432 | 1991-06-19 | US5271812A | 1993-12-21 | Yun Gao; Charles M Zepp |
The invention relates to a process for the production of cyclic sulfates and cyclic sulfamidates from the corresponding cyclic sulfite and cyclic sulfamidite substrate, respectively. The method involves the electrolysis of a solvent mixture containing active metal species, non-metal oxidant species and substrate. | ||||||
105 | 1,3,2-dioxathiolan-s-oxide derivatives, method for preparation, and use therefor | US933032 | 1992-08-20 | US5223531A | 1993-06-29 | Satoru Kumazawa; Masanori Minoguchi |
Disclosed is a 1,3,2-dioxathiolan-S-oxide derivative as represented by the general formula (I): ##STR1## (where R.sub.1 and R.sub.2 are identical to or different from each other and each is a hydrogen atom or a lower alkyl group;X is a halogen atom, a cyano group, a lower alkyl group, a haloalkyl group or a phenyl group;m is 0 or an integer from 1 to 5; and when small m is greater than 1 each x can be the same or different andn is 1 or 2).A 1,3,2-dioxathiolan-2-oxide derivative of the compound as represented by the general formula (I-I) is prepared by reacting a hydroxymethylcyclopentanol derivative with thionyl chloride; and a 1,3,2-dioxathiolan-2,2-dioxide derivative (I-II) thereof is prepared by oxidizing the compound (I-I). The compounds (I) can be employed as fungicides and intermediate compounds for the preparation of azolylmethylcyclopentanol derivatives. | ||||||
106 | Process for the production of cyclopropanenitrile derivatives | US806211 | 1991-12-13 | US5159100A | 1992-10-27 | Paul Hanselmann |
A process for the production of cyclopropanenitrile derivatives. A diol of the formula: ##STR1## wherein R.sub.1 and R.sub.2 are the same or different and each is a hydrogen atom, a C.sub.1 -C.sub.6 alkyl group, branched or unbranched, or a C.sub.1 -C.sub.6 alkenyl group, branched or unbranched, or wherein R.sub.1 and R.sub.2 together is a C.sub.4 -C.sub.6 cycloalkyl ring, is converted with thionyl chloride to a compound of the formula: ##STR2## The latter compound is then oxidized to a compound of the formula: ##STR3## The formula IV compound is converted with a cyano compound to the end product of the formula: ##STR4## | ||||||
107 | Cyclic sulfate compounds | US199157 | 1988-05-26 | US5023342A | 1991-06-11 | K. Barry Sharpless; Yun Gao |
A ruthenium catalyzed method to synthesize cyclic sulfate compounds from the corresponding cyclic sulfites, and the cyclic sulfate reaction products obtained by this method. These cyclic sulfates further react with selected nucleophiles to give various substituted products. The method is an efficient means for the synthesis of chiral building blocks from tartaric acid enantiomers in high yields using an overall two-stage, one-pot reaction procedure. The chiral compounds can be transformed by nucleophilic reactions into chiral building blocks useful for the synthesis of natural biologically active products, such as antibiotics and pheromones. | ||||||
108 | Process for the preparation of cyclic sulphates | US403444 | 1989-09-06 | US4960904A | 1990-10-02 | Pierre Le Roy; Bernadette Mandard-Cazin |
Cyclic sulphates of formula: ##STR1## are prepared by oxidation of a cyclic sulphite of formula: ##STR2## with a hypohalite of an alkali or alkaline-earth metal and a catalytic quantity of a ruthernium derivative (RuO.sub.2, RuCl.sub.3). In formulae (I) and (II), R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5 and R.sub.6 are identical or different and each represents hydrogen, halogen, alkyl, alkoxy, aryl, aryloxy or alkoxycarbonyl. | ||||||
109 | N-alpha-haloacetyl-n-(1,3-dioxan-2-ylalkyl)anilids | US47554474 | 1974-06-03 | US3888882A | 1975-06-10 | RICHTER SIDNEY B; KRENZER JOHN |
This invention discloses new compounds of the formula
WHEREIN Y is selected from the group consisting of hydrogen, lower alkyl and halogen; R1 is selected from the group consisting of hydrogen, lower alkyl and lower alkoxy; R2 is lower alkyl; R3, R4, R5, R6 and R7 are independently selected from the group consisting of hydrogen and lower alkyl; X is halogen; m is an integer from 0 to 2; Z1 and Z2 are independently selected from the group consisting of oxygen and sulfur; and n is an integer from 1 to 2. The compounds of the above description are useful as herbicides. |
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110 | Dioxathiocin carboxylic acids, esters, salts and amides | US3714191D | 1971-09-13 | US3714191A | 1973-01-30 | PARKER R |
Novel dioxathiocin carboxylic acids, esters, salts and amides, which reduce blood lipids in warm blooded animals, are useful in the treatment of hyperlipidemic states and possess anti-infective properties, are represented by compounds of the following formula:
WHEREIN EACH Y, Y'', Z and Z'' represent hydrogen, halogen such as chlorine, fluorine, bromine or iodine, or lower alkyl or from one to four carbon atoms; or each set of Y and Y'' or each set of Z and Z'' forms a napthalene ring which may be unsubstituted or substituted with a substituent selected from a halogen atom such as chlorine, fluorine, bromine or iodine or lower alkyl of from one to four carbon atoms; W represents hydroxy, lower alkoxy of from one to four carbon atoms; or -NR1R2; R1 and R2 represent hydrogen or lower alkyl of from 1 to 4 carbon atoms and may be the same or different; or R1 and R2 taken together with the nitrogen atom to which each is attached form a saturated monocyclic heterocyclic group such as pyrrolidino, piperidino, morpholino, piperazino or N-(lower)-alkyl-piperazino. |
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111 | Bis-quinonemethide precursors | US3634456D | 1969-03-26 | US3634456A | 1972-01-11 | CHEN MARK C; SHEPPARD WILLIAM A |
(1) A NEW COMPOSITION OF MATTER OF THE FORMULA
1-R3,2-R4,3,4-(-O-Z(=O)-O-C(-R1)(-R2)-),5-R5,6-((2-R8,3,4- (-C(-R1)(-R2)-O-Z(=O)-O-),5-R7,6-R6-PHENYL)-(W)X-) BENZENE WHEREIN X=0 OR 18 AND W IS A BIFUNCTIONAL ALIPHATIC OR AROMATIC RADICAL OXYGEN, SULFUR, OXYDIALKYL, OR THIODIALKYL RADICAL; R1 AND R2 ARE EACH INDEPENDENTLY A LOWER ALKYL OR HALOALKYL RADICAL; R3, R4, R5, R6, R7, AND R8 CAN EACH INDEPENDENTLY BE HYDROGEN, A LOWER ALKYL RADICAL OR HALOGEN; AND Z IS EITHER SULFUR OR CARBON. (2) A PROCESS FOR MAKING THE NEW COMPOSITION OF MATTER DESCRIBED IN (1) ABOVE BY CONTACTING A BISPHENOL 1-R3,2-R4,3-(HO-),5-R5,6-((2-R8,4-(HO-),5-R7,6-R6-PHENYL)- (W)X-)BENZENE WITH A LOWER ALKYL KETONE R1-CO-R2 AND FURTHER CONTACTING THE INTERMEDIATE BIS-T-BENZYL ALCOHOL WITH EITHER THIONYL CHLORIDE OR PHOSGENE IN THE PRESENCE OF A TERTIARY AMINE. (3) A PROCESS FOR CURING BY HEATING WITH THE NEW COMPOUNDS OF SECTION (1) ORGANIC POLYMERS CONTAINING "ACTIVE HYDROGEN" ATOMS, "ACTIVATED DOUBLE BONDS," OR ALLYLIC CHORINE. |
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112 | Manufacture of 6,7,8,9,10,10-hexahalo- 1,5,5alpha,6,9,9alpha - hexahydro - 6,9-methano-2,4,3-benzodioxathiepin-3-oxide | US3492312D | 1966-05-31 | US3492312A | 1970-01-27 | LITTLE LAURENCE S; ISROE BERNARD A |
113 | 2,2 - bis(chloromethyl) - 1,3 - propanediol cyclic sulfite as a bird management agent | US3475539D | 1968-01-02 | US3475539A | 1969-10-28 | REINERT ANDREW J; CANTREL KENNETH E; COBB RAYMOND L |
114 | Cyclic sulfates and their preparation | US3454597D | 1966-11-14 | US3454597A | 1969-07-08 | TONG YU-LAN CHANG; TOMALIA DONALD A; SHEETZ DAVID P |
115 | Polymerization of aromatic cyclic carbonate monomers | US39206064 | 1964-07-01 | US3220980A | 1965-11-30 | PROCHASKA ROBERT J |
116 | 2, 2, 3, 3-tetrachloro-1, 4-butanediol sulfite | US8099061 | 1961-01-06 | US3169130A | 1965-02-09 | CHIDDIX MAX E; WYNN ROBERT W |
117 | Stabilization of 6, 7, 8, 9, 10, 10-hexachloro-1, 5, 5 alpha, 6, 9, 9 alpha-hexahydro-6, 9-methano-2, 4, 3-benzodioxathiepin-3-oxide with water | US80091259 | 1959-03-23 | US3105081A | 1963-09-24 | KIMBALL RICHARD H; EDWARD LEON |
118 | Preparation of cyclic sulfites | US62154756 | 1956-11-13 | US3022315A | 1962-02-20 | ROGERS JR WILLIAM A; LAKE JACKSON; WOEHST JAMES E; SMITH ROBERT M |
119 | Pentaerythrite dihalohydrin monosulfurous acid esters | US30283452 | 1952-08-05 | US2708200A | 1955-05-10 | HELMUT PIETSCH; HORSTMAR NAGEL |
120 | Nitroalkyl sulfites and process for preparing them | US68694746 | 1946-07-29 | US2471274A | 1949-05-24 | LINGO SHIRLEY P |