序号 | 专利名 | 申请号 | 申请日 | 公开(公告)号 | 公开(公告)日 | 发明人 |
---|---|---|---|---|---|---|
181 | Ruthenium-catalyzed production of cyclic sulfates | US369189 | 1989-06-21 | US5112990A | 1992-05-12 | K. Barry Sharpless; Yun Gao |
A ruthenium catalyzed method to synthesize cyclic sulfate compounds from the corresponding cyclic sulfites, and the cyclic sulfate reaction products obtained by this method. These cyclic sulfates further react with selected nucleophiles to give various substituted products. The method is an efficient means for the synthesis of chiral building blocks from tartaric acid enantiomers in high yields using an overall two-stage, one-pot reaction procedure. The chiral compounds can be transformed by nucleophilic reactions into chiral building blocks useful for the synthesis of natural biologically active products, such as antibiotics and pheromones. | ||||||
182 | Process for the preparation of cyclic sulphates | US351831 | 1989-05-15 | US4924007A | 1990-05-08 | Viviane Massonneau; Michel Mulhauser |
Cyclic sulphates of formula ##STR1## in which R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, and R.sub.6, which are identical or different, each denote hydrogen, halogen, alkyl, alkoxy, aryloxy or alkoxycarbonyl and n is 0 or 1, are prepared by rapid reaction, at a temperature of 150.degree. to 250.degree. C., of concentrated sulphuric acid with a glycol of formula ##STR2## | ||||||
183 | Process for producing intermediate furanones from diol derivative and thionyl chloride | US753493 | 1985-07-10 | US4596879A | 1986-06-24 | Christian Fizet |
A novel process for the manufacture of the furanone of the formula ##STR1## is described. In this process, a diol is firstly reacted with thionyl chloride, then the sulphite formed, optionally after oxidation to the corresponding sulphate, is treated with sodium cyanide and the resulting hydroxynitrile is hydrolyzed.The furanone of formula I can be used as a starting material for the manufacture of R-(-)-pantolactone. | ||||||
184 | Herbicidal urea compounds | US504349 | 1983-06-14 | US4533379A | 1985-08-06 | Robert van Helden; Frank Baardman; Johannes L. M. Syrier |
Novel compounds of the general formula ##STR1## wherein R represents a hydrogen or halogen atom or a (cyclo) alkyl group, R.sup.3 represents H, CH.sub.3, or OCH.sub.3, n=0 or 1, and when n=0, R.sup.2 represents a hydrogen atom and R.sup.1 a hydrogen atom or a monovalent substituent thereby forming an alkoxide, ether, ester, or other alcohol derivative, and when n=1, each R.sup.1 and R.sup.2 independently represents one of the atoms specified for R.sup.1 when n=0, or R.sup.1 and R.sup.2 together represent a bivalent group thereby forming a cyclic ether, ester, or other diol derivative, have useful herbicidal properties. | ||||||
185 | Process for polycyclic amines | US917924 | 1978-06-22 | US4249003A | 1981-02-03 | Edgar Eriksoo |
This invention relates to a new method for the preparation of amines containing alkylene groups by using cyclic alkylene sulphuric esters, and novel intermediates for use in the method.The new method is useful for preparation of i.a. pharmaceuticals. The novel intermediates are useful i.a. as surfactants. | ||||||
186 | Certain herbicidal sulfonates and sulfamates | US22599 | 1979-03-21 | US4222767A | 1980-09-16 | Peter S. Gates; Derek Baldwin |
The invention provides herbicidally-active sulphonates of the formula ##STR1## wherein X represents a group --CHR.sup.3 --OR.sup.4 and Y represents a group --OR.sup.5, or X and Y together represent a group --CHR.sup.3 --O-- or a group --CHR.sup.3 --O--Z--O--, the free oxygen atom of which is attached to the benzene ring; R.sup.1, R.sup.2 and R.sup.3, which may be the same or different, each represent hydrogen or C 1 to 6 alkyl, or R.sup.1 and R.sup.2 together or R.sup.2 and R.sup.3 together form a C 3 to 6 alkylene chain; R.sup.4 and R.sup.5, which may be the same or different, each represent hydrogen, C 1 to 6 alkyl, C 2 to 6 alkenyl, C 2 to 6 alkynyl, phenyl, a group --C(.dbd.O)R.sup.10 or a group --SO.sub.2 R.sup.11 ; R.sup.6, R.sup.7 and R.sup.8, which may be the same or different, each represent hydrogen, C 1 to 6 alkyl, halogen, cyano, C 2 to 6 carboxylic acyl, or C 1 to 4 alkoxy; R.sup.9 represents C 1 to 6 alkyl, phenyl or C 7 to 10 phenylalkyl (each of which may be unsubstituted or substituted by one or more chlorine or bromine atoms, C 1 to 4 alkyl groups, C 1 to 4 alkoxy groups or nitro groups), C 5 to 7 cycloalkyl, C 1 to 4 alkylamino, or dialkylamino wherein each alkyl moiety has from 1 to 4 carbon atoms; R.sup.10 represents C 1 to 6 alkyl or alkoxy, C 2 to 6 alkenyl or alkenyloxy, C 2 to 6 alkynyl or alkynyloxy, phenyl, phenoxy, phenylamino, C 1 to 6 alkylamino or dialkylamino wherein each alkyl moiety has from 1 to 6 carbon atoms, each of the groups which R.sup.10 may represent being unsubstituted or substituted by one or more halogen atoms or C 1 to 4 alkoxy groups; R.sup.11 represents C 1 to 6 alkyl, phenyl, C 1 to 6 alkylamino or dialkylamino each of the alkyl moieties thereof having from 1 to 6 carbon atoms, each of the groups which R.sup.11 may represent being unsubstituted or substituted by one or more halogen atoms or C 1 to 4 alkoxy groups; Z represents a group of formula --S(.dbd.O)n, --CR.sup.12 R.sup.13 or --P(.dbd.Q)(OR.sup.14)--; n represents 1 or 2; R.sup.12 and R.sup.13, which may be the same or different, each present hydrogen, C 1 to 6 alkyl or alkoxy, C 2 to 6 alkenyl or alkynyl, phenyl, phenoxy, cyano or (C 1 to 6 alkoxy)carbonyl, or R.sup.12 and R.sup.13 together represent an oxygen atom, a sulphur atom, a C 3 to 6 alkylene chain or a C 1 to 6 alkylimino group or a phenylimino group; and R.sup.14 represents C 1 to 6 alkyl; and Q represents oxygen or sulphur, together with processes for their preparation and herbicidal compositions containing them. | ||||||
187 | Herbicidally-active sulphonates | US875189 | 1978-02-03 | US4162154A | 1979-07-24 | Peter S. Gates; Derek Baldwin |
The invention provides herbicidally-active sulphonates of the formula ##STR1## wherein X represents a group --CHR.sup.3 --OR.sup.4 and Y represents a group --OR.sup.5, or X and Y together represent a group --CHR.sup.3 --O-- or a group --CHR.sup.3 --O--Z--O--, the free oxygen atom of which is attached to the benzene ring; R.sup.1, R.sup.2 and R.sup.3, which may be the same or different, each represent hydrogen or C 1 to 6 alkyl, or R.sup.1 and R.sup.2 together or R.sup.2 and R.sup.3 together form a C 3 to 6 alkylene chain; R.sup.4 and R.sup.5, which may be the same or different, each represent hydrogen, C 1 to 6 alkyl, C 2 to 6 alkenyl, C 2 to 6 alkynyl, phenyl, a group --O(.dbd.O)R.sup.10 or a group --SO.sub.2 R.sup.11 ; R.sup.6, R.sup.7 and R.sup.8, which may be the same or different, each represent hydrogen, C 1 to 6 alkyl, halogen, cyano, C 2 to 6 carboxylic acyl, or C 1 to 4 alkoxy; R.sup.9 represents C 1 to 6 alkyl, phenyl or C 7 to 10 phenylalkyl (each of which may be unsubstituted or substituted by one or more chlorine or bromine atoms, C 1 to 4 alkyl groups, C 1 to 4 alkoxy groups or nitro groups), C 5 to 7 cycloalkyl, C 1 to 4 alkylamino, or dialkylamino wherein each alkyl moiety has from 1 to 4 carbon atoms; R.sup.10 represents C 1 to 6 alkyl or alkoxy, C 2 to 6 alkenyl or alkenyloxy, C 2 to 6 alkynyl or alkynyloxy, phenyl, phenoxy, phenylamino, C 1 to alkylamino alylamino or dialkylamino wherein each alkyl moiety has from 1 to 6 carbon atoms, each of the groups which R.sup.10 may represent being unsubstituted or substituted by one or more halogen atoms or C 1 to 4 alkoxy groups; R.sup.11 represents C 1 to 6 alkyl, phenyl, C 1 to 6 alkylamino or dialkylamino each of the alkyl moieties thereof having from 1 to 6 carbon atoms, each of the groups which R.sup.11 may represent being unsubstituted or substituted by one or more halogen atoms or C 1 to 4 alkoxy groups; Z represents a group of formula--S(.dbd.O)n, --CR.sup.12 R.sup.13 or --P(.dbd.Q)(OR.sup.14)--;n represents 1 or 2; R.sup.12 and R.sup.13, which may be the same or different, each represent hydrogen, C 1 to 6 alkyl or alkoxy, C 2 to 6 alkenyl or alkynyl, phenyl, phenoxy, cyano or (C 1 to 6 alkoxy)carbonyl, or R.sup.12 and R.sup.13 together represent an oxygen atom, a sulphur atom, a C 3 to 6 alkylene chain or a C 1 to 6 alkylimino group or a phenylimino group; and R.sup.14 represents C 1 to 6 alkyl; and Q represents oxygen or sulphur, together with processes for their preparation and herbicidal compositions containing them. | ||||||
188 | Dioxolane substituted .alpha.-haloanilides as herbicides | US475464 | 1974-06-03 | US3942972A | 1976-03-09 | Sidney B. Richter; John Krenzer |
This invention discloses new compounds of the formula ##EQU1## wherein Y is selected from the group consisting of hydrogen, lower alkyl and halogen; R.sup.1 is selected from the group consisting of hydrogen, lower alkyl and lower alkoxy; R.sup.2 is lower alkyl; R.sup.3, R.sup.4, R.sup.5, R.sup.6 and R.sup.7 are independently selected from the group consisting of hydrogen and lower alkyl; X is halogen; m is an integer from 0 to 2; Z.sup.1 and Z.sup.2 are independently selected from the group consisting of oxygen and sulfur; and n is an integer from 1 to 2. The compounds of the above description are useful as herbicides. | ||||||
189 | Dioxane substituted-.alpha.-haloanilides as herbicides | US475461 | 1974-06-03 | US3940259A | 1976-02-24 | Sidney B. Richter; John Krenzer |
This invention discloses new compounds of the formula ##EQU1## wherein Y is selected from the group consisting of hydrogen, lower alkyl and halogen; R.sup.1 is selected from the group consisting of hydrogen, lower alkyl and lower alkoxy; R.sup.2 is lower alkyl; R.sup.3, R.sup.4, R.sup.5, R.sup.6 and R.sup.7 are independently selected from the group consisting of hydrogen and lower alkyl; X is halogen; m is an integer from 0 to 2; Z.sup.1 and Z.sup.2 are independently selected from the group consisting of oxygen and sulfur; and n is an integer from 1 to 2. The compounds of the above description are useful as herbicides. | ||||||
190 | Dithiolanyl anilids | US47554374 | 1974-06-03 | US3894046A | 1975-07-08 | RICHTER SIDNEY B; KRENZER JOHN |
This invention discloses new compounds of the formula
WHEREIN Y is selected from the group consisting of hydrogen, lower alkyl and halogen; R1 is selected from the group consisting of hydrogen, lower alkyl and lower alkoxy; R2 is lower alkyl; R3, R4, R5, R6 and R7 are independently selected from the group consisting of hydrogen and lower alkyl; X is halogen, m is an integer from 0 to 2; Z1 and Z2 are independently selected from the group consisting of oxygen and sulfur; and n is an integer from 1 to 2. The compounds of the above description are useful as herbicides. |
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191 | Cyclic thionosulfites and their preparation | US42167264 | 1964-12-28 | US3357993A | 1967-12-12 | THOMPSON QUENTIN E |
192 | Fluorosultones and sulfites, and the preparation of the latter | US55222455 | 1955-12-09 | US3163656A | 1964-12-29 | LYNDE ANDERSON JOHN; ENGLAND DAVID C |
193 | Process for preparing cyclic lower alkylene sulfates | US14802261 | 1961-10-27 | US3100780A | 1963-08-13 | KLASS DONALD L |
194 | Process for the preparation of organic cyclic sulfites | US73350058 | 1958-05-07 | US2983732A | 1961-05-09 | GEERING EMIL J; NELSON SAMUEL J |
195 | Pentaerythrite-dichlorhydrine monosulfurous acid esters | US28531152 | 1952-04-30 | US2708198A | 1955-05-10 | HELMUT PIETSCH |
196 | PROCESS FOR PREPARATION OF 13,14-DIHYDRO-PGF2a DERIVATIVES | PCT/PL2006000023 | 2006-04-18 | WO2006112742A3 | 2006-12-28 | MARTYNOW JACEK; JOZWIK JULITA; SZELEJEWSKI WIESLAW; ACHMATOWICZ OSMAN; KUTNER ANDRZEJ; WISNIEWSKI KRZYSZTOF; WINIARSKI JERZY; ZEGROCKA-STENDEL OLIWIA; GOLEBIEWSKI PIOTR |
Invention relates to the process for preparation of 13,14-dihydro-PGF2a derivatives of R or S configuration at carbon atom in omega chain substituted by hydroxyl, represented by formula (I), wherein the meaning of substituents is defined in the description. Compounds (I) are valuable biologically active substances or intermediates thereof. The invention especially relates to the process for preparation of 13,14-dihydro-15(R)-17-substituted-18,19,20-trinor-PGF2a, ie. latanoprost. | ||||||
197 | PROCESS FOR THE SYNTHESIS OF N-(4-CYANO-3-TRIFLUOROMETHYLPHENYL)-3-(4-FLUOROPHENYLSULFONYL)-2-HYDROXY-2-METHYLPROPIONAMIDE | PCT/HU0000049 | 2000-05-26 | WO0100608A8 | 2001-06-21 | SOEROES BELA; TUBA ZOLTAN; GALIK GYOERGY; BOR ADAM; DEMETER ADAM; TRISCHLER FERENC; HORVATH JANOS; BRLIK JANOS |
Racemic or optically pure N-(4-cyano-3-trifluoromethylphenyl)-3-(4 -fluorophenylsulphonyl)-2-hydroxy-2-methylpropionamide of formula (I) is prepared by the following process: 2,3-dihydroxy-2-methylpropionic acid of formula (VII) is reacted with thionyl chloride to form 4-chlorocarbonyl-4-methyl-1,3,2-dioxathiolane-2-one of formula (VI), which is reacted with 4-cyano-3-trifluoromethylaniline. The resulting 4-{[4-cyano-3-(trifluoromethyl)anilino]carbonyl}-4-methyl-1,3,2-dioxathiolane-2-one of formula (V) is hydrolysed to form N-[4-cyano-3-(trilfuoromethyl)phenyl]-2,3-dihydroxy-2-methylpropionamide of formula (IV), which is sulfonylated with a sulfonyl halogenide of formula R-SO2-X, in a halogenated hydrocarbon solvent in the presence of a tertiary amine base. The sulphonic ester derivative of formula (III) obtained is reacted with 4-fluorothiophenol in the presence of a base to give a thioether of formula (II) which is oxidized using an inorganic peroxy compound or aqueous hydrogen peroxide. | ||||||
198 | NONAQUEOUS ELECTROLYTE, CAPACITOR DEVICE USING SAME, AND CARBOXYLIC ACID ESTER COMPOUND USED IN SAME | US15103220 | 2014-12-17 | US20180166746A1 | 2018-06-14 | Kei SHIMAMOTO; Koji ABE; Shoji SHIKITA; Kazuhiro MIYOSHI |
The present invention provides a nonaqueous electrolytic solution capable of improving electrochemical characteristics in the case of using an energy storage device at a high temperature and at a high voltage and further capable of inhibiting the gas generation while maintaining a capacity retention rate after storage at a high temperature and at a high voltage and also provides an energy storage device using the same. Disclosed is a nonaqueous electrolytic solution having an electrolyte salt dissolved in a nonaqueous solvent, the nonaqueous electrolytic solution containing a carboxylic acid ester compound represented by the following general formula (I). In the formula, each of R1 and R2 independently represents a hydrogen atom, a —C(═O)—OR4 group, or the like, and R1 and R2 may be bonded to each other to form a ring structure. R3 represents a hydrogen atom or the like, and n represents an integer of 1 to 3. When n is 1, then L and R4 represent an alkyl group having 1 to 6 carbon atoms or the like; and when n is 2 or 3, then L represents an n-valent connecting group, X represents a —C(═O)— group, an —S(═O)— group, an —S(═O)2— group, an —S(═O)2—R5—S(═O)2— group or a CR6R7 group, R5 represents an alkylene group having 1 to 4 carbon atoms, and each of R6 and R7 represents a hydrogen atom or an alkyl group having 1 to 6 carbon atoms. | ||||||
199 | Oxathiazine derivatives as antibacterial and anticancer agents | US15472550 | 2017-03-29 | US09844555B2 | 2017-12-19 | Rolf W. Pfirrmann |
New oxathiazin-like compounds and their derivatives are useful as antineoplastic and antimicrobial agents. Compositions and methods of using oxathiazin-like compounds and their derivatives are disclosed. | ||||||
200 | Cyclic (poly)glycerol sulphates and preparation and use thereof | US14356512 | 2011-11-10 | US09371306B2 | 2016-06-21 | Pascal Metivier; Yan Zhao; Zhaoyu Fan; Chenjiang Zhu |
The present invention relates to novel cyclic sulphates of (poly)glycerol, particularly to the novel compound of 4-(hydroxymethyl)-1,3,2-dioxathiolane-2,2-dioxide. The present invention also relates to the preparation process of the cyclic sulphate compounds, and to the use thereof as an intermediate to prepare green surfactants containing sulphate groups. |