子分类：
| 序号 | 专利名 | 申请号 | 申请日 | 公开（公告）号 | 公开（公告）日 | 发明人 |
|---|---|---|---|---|---|---|
| 121 | Methods for embolizing blood vessels | US09680944 | 2000-10-10 | US06335384B1 | 2002-01-01 | Scott Evans; John Perl, II; Richard Greff |
| Disclosed are methods useful for treating vascular lesions wherein a non-particulate agent such as a metal coil is introduced into a vascular site (e.g., an aneurysm cavity) in conjunction with an embolizing composition comprising a biocompatible polymer and a biocompatible solvent. The biocompatible solvent is miscible or soluble in blood and also solubilizes the polymer during delivery. The biocompatible polymer is selected to be soluble in the biocompatible solvent but insoluble in blood. Upon contact with the blood, the biocompatible solvent dissipates from the embolic composition whereupon the biocompatible polymer precipitates. Precipitation of the polymer in the presence of the non-particular agent permits the agent to act as a structural lattice for the growing polymer precipitate. In another embodiment, the biocompatible polymer composition can be replaced with a biocompatible prepolymer composition containing a biocompatible prepolymer. | ||||||
| 122 | Adhesive for secure topical attachment to the skin and comfortable removal | US09331694 | 1999-06-23 | US06211263B1 | 2001-04-03 | Fabio Cinelli; Peter Coles; Italo Corzani |
| The present invention relates to a combination of a substrate with combinations for attachment to the skin. In particular the present invention relates to a combination of a substrate which can be employed for attachment to the skin of articles such as protective articles, clothing, prosthesis, heat wraps, pads, and/or packs, cold wraps hearing, protective face masks, ornamental articles or eye wear, or also of functional articles such as cosmetic or pharmaceutical delivery articles that provide a substance to the skin. The combination provides secure attachment and is pleasing to the skin upon application, yet causes no discomfort upon removal. This is achieved by selecting the chemical composition and heological characteristics of the combinations and the physical characteristics of the substrate on which the combination is applied. | ||||||
| 123 | Adhesive for secure topical attachment to the skin and comfortable removal | US09331741 | 1999-06-23 | US06191189B1 | 2001-02-20 | Fabio Cinelli; Peter Coles; Italo Corzani |
| The present invention relates to a combination of a substrate with topical adhesives for attachment to the skin. In particular the present invention relates to a combination of a substrate with a topical adhesive which can be employed for attachment to the skin in the area where absorption of bodily liquids is desired. The combination provides secure attachment and is pleasing to the skin upon application, yet causes no discomfort upon removal. This is achieved by selecting the chemical composition and rheological characteristics of the topical adhesives and the physical characteristics of the substrate on which the topical adhesive is applied. | ||||||
| 124 | Methods for embolizing blood vessels | US868931 | 1997-06-04 | US6017977A | 2000-01-25 | Scott Evans; John Perl, II; Richard Greff |
| Disclosed are methods useful for treating vascular lesions wherein a non-particulate agent such as a metal coil is introduced into a vascular site (e.g., an aneurysm cavity) in conjunction with an embolizing composition comprising a biocompatible polymer and a biocompatible solvent.The biocompatible solvent is miscible or soluble in blood and also solubilizes the polymer during delivery. The biocompatible polymer is selected to be soluble in the biocompatible solvent but insoluble in blood. Upon contact with the blood, the biocompatible solvent dissipates from the embolic composition whereupon the biocompatible polymer precipitates. Precipitation of the polymer in the presence of the non-particulate agent permits the agent to act as a structural lattice for the growing polymer precipitate.In another embodiment, the biocompatible polymer composition can be replaced with a biocompatible prepolymer composition containing a biocompatible prepolymer. | ||||||
| 125 | Hydrophilic composite polymer articles formed from a settable paste comprising a mixture of hydrophilic polymer and unsaturated monomer | US295357 | 1994-08-24 | US5468811A | 1995-11-21 | Daniel G. Moro; Samuel H. Ronel; Petr Kuzma |
| Hydrophilic composite polymer articles are provided which comprise at least one hydrophilic polymer in a powder form and one or more liquid components of which at least one is hydrophilic and which can be polymerized with said hydrophilic polymer. This composition is produced from a homogeneously mixed paste which can be molded or cast into a desired shape which will subsequently set. The resulting article has a shape-retaining, non-tacky flexible consistency which allows the shape to be further modified, if necessary.Such object can be then cured by any of the conventional curing methods to retain its shape permanently. The final properties of the composite can be tailored to suit the final application by using fillers or modifiers. In the medical field, such articles can be utilized as a sustained release devices as they can be loaded with the desired therapeutic drugs. These articles can be made non-toxic and biocompatible and used as prosthetic devices.The final cured article can be modified further by polishing, drilling, cutting, etc. When exposed to moisture or a humid environment, the article will become partially hydrated with a resultant softer surface yet retain good mechanical strength. | ||||||
| 126 | オストミー装置 | JP2017540766 | 2016-02-02 | JP2018508260A | 2018-03-29 | エスペン ストレーベク |
| 使用者の皮膚表面に取り付けるための接着剤ウェハと、ストーマからの排出物を収集するための収集バッグとを備えたオストミー装置が開示される。収集バッグは接着剤ウェハに接続され、接着剤ウェハは、使用者のストーマを収容するための貫通孔を有する。接着剤ウェハは、バッキング層、第1の切り替え可能な接着剤組成物(11)、第2の吸収性接着剤組成物(12)、および剥離ライナを含む。【選択図】図1 | ||||||
| 127 | 塞栓形成用製剤及びマイクロカテーテル | JP2016555208 | 2015-10-19 | JPWO2016063824A1 | 2017-08-31 | 努 玉井; 孝行 武井; 章雄 井戸; 吉田 昌弘; 昌弘 吉田; 慎司 境 |
| 抗がん剤の保持及び徐放ができ、血管に注入することによって血管内を閉塞し、wash outされにくく、分解時間がコントロールされた(すなわち、組織全体が壊死しないように、しばらくの間血管を閉塞し、機能を終えた後は速やかに分解される)、生体への安全性が高い塞栓形成用製剤を提供することを目的とする。本発明の塞栓形成用製剤は、下記式(1):(式中、Pは生体適合性ポリマーであり、Aは単結合であるか、又は−OCO−C2〜C4−アルケニレン基、−CONH−C1〜C4−アルキレン基もしくは−HNCO−C1〜C4−アルキレン基であり、Xは水素又はC1〜C3−アルコキシ基である)で表されるフェノール性水酸基修飾ポリマーを含む溶液と、ペルオキシダーゼ、ラッカーゼ、チロシナーゼ、カタラーゼ及び鉄ポルフィリン錯体から選択される一種以上を含む溶液と、過酸化水素を含む溶液と、を含むことを特徴とする。 | ||||||
| 128 | 外科用シーラント | JP2016009257 | 2016-01-20 | JP2017127497A | 2017-07-27 | 田口 哲志 |
| 【課題】放射線保護物質等を添加することなく滅菌することができ、且つ、簡易且つ安全に製造することができる外科用シーラントを提供する。 【解決手段】 (1)イミノ基を介して、疎水性基が結合されてなるゼラチン誘導体を含む第1剤であって、該ゼラチン誘導体は (a)重量平均分子量が10,000〜50,000であり、 (b)該疎水性基が炭素数6〜18のアルキル基であり、且つ (c)該ゼラチン誘導体中のイミノ基/アミノ基(モル比)が1/99〜30/70である、 第1剤、及び (2)該ゼラチン誘導体の架橋剤を含む第2剤 からなる外科用シーラント。 【選択図】なし |
||||||
| 129 | 生体活性材料 | JP2010521471 | 2008-08-19 | JP6165408B2 | 2017-07-19 | グレイム・ハウリング; ポール・ガニング |
| 130 | Injectable hydrogel, method for preparing hydrogel, hydrogel preparation kit, and use of hydrogel and method thereof | JP2014046747 | 2014-03-10 | JP2014177460A | 2014-09-25 | LISA MELLIN; NIKLAS BORG; MARTINA KAELLROT JANSTAL |
| PROBLEM TO BE SOLVED: To provide a quickly preparable and low-risk method for preparing hydrogel comprising an injectable thiol group, and to provide a hydrogel preparation kit, and to provide a use of hydrogel and a method thereof.SOLUTION: Hydrogel is prepared by binding (a) a water soluble polymer containing a thiol group to (b) a water soluble metal salt in an aqueous solution. Hydrogel can be prepared quickly to be used as blood vessel sealant, a vessel closing device or a drug delivery carrier. Preferably, AuClis used as a metal salt. As a water soluble polymer, Polysaccharide, gelatin, cellulose, starch, lipid, albumin, collagen, polylysine, or the like is used. The water soluble polymer comprises polyethylene glycol comprising at least four branches. The hydrogel is biodegradable and is prepared in less than about 60 seconds. | ||||||
| 131 | Drug-containing adhesive preparation | JP2008024967 | 2008-02-05 | JP5227041B2 | 2013-07-03 | 真人 西村; 左知子 寺師; 史朗 里田; 敬悟 井ノ阪; 賢介 松岡 |
| 132 | Compositions for temporarily occluding the intestine | JP2012548307 | 2011-01-12 | JP2013517015A | 2013-05-16 | ビショフ、ゲオルグ |
| 本発明は、哺乳動物の腸の一時的な閉塞を形成するための固体化可能な組成物の使用に関する。 該組成物は、流動性を有し、かつ、固体化可能であって、腸内の所望の部位において固体プラグを形成し、該プラグの構造は、閉塞のその後の少なくとも部分的な除去を可能とするために変化できる。
【選択図】図１ |
||||||
| 133 | Polymer having both biocompatibility and thermoresponsive | JP2005504205 | 2004-03-26 | JP4746984B2 | 2011-08-10 | 政嗣 下村; 直子 伊土; 賢 田中 |
| 134 | 可視光硬化型接着剤 | JP2009552569 | 2009-02-06 | JPWO2009099253A1 | 2011-06-02 | 伊藤 嘉浩; 伊藤 嘉浩; 泰一 孫; 右副 田島 |
| 本発明は、可視光照射により硬化可能な水溶性の生体接着剤を提供することを目的とする。本発明は、可視光照射下でラジカルを発生する水溶性の酸素増感剤と、可視光照射下で前記酸素増感剤から発生する一重項酸素を介して活性化され得る官能基を有する水溶性の高分子化合物とを含有する、可視光硬化型接着剤を提供する。 | ||||||
| 135 | Biological material made of bone materials and cement complex and hardened cement paste | JP2003127616 | 2003-05-02 | JP4535691B2 | 2010-09-01 | 啓 寺岡; 幸弘 松山; 直樹 石黒 |
| An aggregate particles cement composite containing aggregate particles made of a biocompatible material, characterized in that (1) the above aggregate particles are made of a calcium phosphate based ceramic or a biodegradable plastic, (2) the aggregate particles have a particle diameter of 151 mum to 5 mm, (3) the content of the aggregate particles in the cement is 51 to 90 vol %, and (4) the cement is a self-hardening calcium phosphate cement; an injecting or packing agent for a living organism comprising the composite; a tube having therein the above agent; a device for ejecting the agent comprising the tube; a cement hardened material comprising the composite; and a method for controlling mechanical properties and the like of the hardened material. | ||||||
| 136 | Bioabsorbable surgical composition | JP2009237500 | 2009-10-14 | JP2010094513A | 2010-04-30 | STOPEK JOSHUA; HADBA AHMAD |
| <P>PROBLEM TO BE SOLVED: To provide a bioabsorbable surgical composition suitably used in vivo, and a method for using the same. <P>SOLUTION: The bioabsorbable surgical composition is a bioabsorbable macromer composition represented by the formula selected from the group consisting of R<SB>1</SB>-[A]<SB>v</SB>-R<SB>2</SB>and R<SB>2</SB>-[A]<SB>v</SB>-R<SB>1</SB>-[A]<SB>v</SB>-R<SB>2</SB>(wherein R<SB>1</SB>includes a hydroxamate segment, R<SB>2</SB>includes a polymer segment selected from the group consisting of a polysaccharide and a polyol, A is a bioabsorbable group and v is a number of about 1-20). <P>COPYRIGHT: (C)2010,JPO&INPIT | ||||||
| 137 | Biological repair material having an affinity with the living body tissue adhesive | JP2002253322 | 2002-08-30 | JP4445697B2 | 2010-04-07 | 正哉 岩木; 弘 氏家; 嘉昭 鈴木; 範吉 高橋 |
| An object of the present invention is to provide a means for improving the affinity of an in vivo embedded material such as an artificial blood vessel or an artificial dura mater with a tissue adhesive, so as to quickly prevent the leakage of the blood or spinal fluid. The present invention provides a polymeric material used in combination with a tissue adhesive, which comprises carbon or silicon as a constitutional element, and at least a portion of the surface of which is modified by ion bombardment. | ||||||
| 138 | Method for making a bone cement composition, and this | JP2008528373 | 2006-08-04 | JP2009545332A | 2009-12-24 | ロベルト ウェンツ; イョルグ メイヤー |
| 脊椎手術における使用の適した組成物がここで開示される。 該組成物は一般に、第１および第２の成分の反応生成物または設定可能な混合物を含み、前記第１の成分はスプレー乾燥された無機フィラー、ラジアルドナー、および、プリ重合されるビニールポリマーを含み、前記第２の成分はラジカルスカベンジャー、希釈液、重合促進剤、および、反応性モノマーを含む。 さらに、前記組成物を作る方法がここで開示され、それは一般に、治癒可能な反応生成物が形成されるのに適した条件の下で前記第１および第２の成分を混合することを含む。 | ||||||
| 139 | Safety and locally attached to the skin, the adhesive for removing comfortably | JP52896698 | 1997-12-22 | JP4279355B2 | 2009-06-17 | コールズ、ペーター; コルツァーニ、イターロ; チネッリ、ファビオ |
| The present invention relates to topical adhesives for attachment to the skin. In particular the present invention relates to such topical adhesives which can be employed for attachment to the skin of protective articles, clothing, prosthesis, heat wraps, pads, and/or packs, e.g. for topical relief of pain or simply to provide warmth; cold wraps, hearing aids, protective face masks, ornamental articles, or eye wear but excluding absorbent articles. The topical adhesive provides secure attachment and is pleasing to the skin upon application, yet causes no discomfort upon removal. This is achieved by selecting the chemical composition and rheological characteristics of the topical adhesives. | ||||||
| 140 | Drug-containing patch preparation | JP2008024967 | 2008-02-05 | JP2008239603A | 2008-10-09 | NISHIMURA MASATO; TERASHI SACHIKO; SATODA SHIRO; INOSAKA KEIGO; MATSUOKA KENSUKE |
| PROBLEM TO BE SOLVED: To provide a patch preparation which is hard for a drug sufficiently dissolved in a pressure-sensitive adhesive layer to separate from the pressure-sensitive adhesive layer in storage of the patch preparation. SOLUTION: The patch preparation has the pressure-sensitive adhesive layer on at least one surface of a substrate, wherein the pressure-sensitive adhesive layer comprises a first synthetic rubber having a viscosity-average molecular weight of 1,600,000-6,500,000, a drug, an organic liquid component, and a tackifier. The organic liquid component is present in the pressure-sensitive adhesive layer in an amount of not less than 20 wt.% based on the total weight of the pressure-sensitive adhesive layer. COPYRIGHT: (C)2009,JPO&INPIT | ||||||
QQ群二维码
意见反馈
意见反馈