序号 专利名 申请号 申请日 公开(公告)号 公开(公告)日 发明人
181 Bioabsorbable surgical composition EP12185044.0 2009-10-14 EP2570441A2 2013-03-20 Stopek, Joshua; Hadba, Ahmad

Bioabsorbable macromer compositions are provided including a polymeric component possessing a hydroxamate segment and a polymer segment. The polymeric component can be used by itself, or in some embodiments, combined with a second component, to form a macromer composition of the present disclosure. The resulting bioabsorbable macromer composition can be employed as an adhesive or sealant for medical/surgical uses.

182 ZUSAMMENSETZUNG ZUR ERZEUGUNG EINER TEMPORÄREN DARMOKKLUSION EP11705422.1 2011-01-12 EP2523700A1 2012-11-21 Bischof, Georg
The present invention relates to the use of a solidifiable composition for producing a temporary occlusion of the intestine of a mammal, wherein the composition is flowable and solidifiable to form a solid plug at a desired location in the intestine. The structure of said plug can be modified for the subsequent, at least partial removal of the occlusion.
183 BIOLOGICAL REPAIR MATERIAL COMPATIBLE WITH BIOLOGICAL TISSUE ADHESIVE EP03797534.9 2003-08-29 EP1535632B1 2011-08-03 SUZUKI, Yoshiaki; UJIIE, Hiroshi; TAKAHASHI, Noriyoshi; IWAKI, Masaya
It is intended to provide a means of more quickly preventing the leakage of blood or spinal fluid by improving the compatibility between an implant material (an artificial vessel, an artificial pachymeninx, etc.)and a biological tissue adhesive. Namely, a polymer material to be used together with a biological tissue adhesive which is made of a polymer material containing carbon or silicon as a constituting element and at least a part of the surface of which is modified by an ionic impact.
184 Knochenzement mit verbesserten mechanischen Eigenschaften und Verfahren zu seiner Herstellung EP07090086.5 2003-10-17 EP1862187B1 2011-03-02 Schilke, Frank; Nies, Berthold; Jeschke, Brigitte; Koch, Matthias; Kübelbeck, Armin
185 BIOACTIVE MATERIAL EP08788378.1 2008-08-19 EP2200669A2 2010-06-30 HOWLING, Graeme; GUNNING, Paul
The present invention relates to a bioactive material and to a method of producing a bioactive material which is suitable for use as an implant or for use as a bone substitute for repairing bone.
186 HOMOGENEOUS, INTRINSIC RADIOPAQUE EMBOLIC PARTICLES EP07834652.5 2007-10-31 EP2125068A2 2009-12-02 KOOLE, Levinus Hendrik; VAN HOOY-CORSTJENS, Catharina Sibilla Josephine
The invention is directed to embolic material comprising spherical, homogeneous and substantially non-porous radiopaque polymer particles based on at least one hydrophilic monomer and at least one radiopaque monomer according to general formula (I): wherein R is H, methyl or ethyl, and R1 is I, Br or formula (II): wherein R2 is O, NH, 0-[CH2-CH2-O]P-C(O)-, O- [CH2] m-O-C(O)-, O-[CH2]p-, NH-[CH2-CH2-O]p-C(O)-, NH-[CH2]m-O-C(O)- or NH-[CH2]p- wherein m>l and p≥l, R3 is I or Br and n is 1, 2 or 3, the iodine and/or bromine content being at least 5 wt.% based on the dry weight of the particle, the said particles having an average particle diameter of at least 10 μm and being able to imbibe water up to a volume increase of the particle of at least 10 %.
187 REDOX CURING-TYPE NONAQUEOUS CURABLE COMPOSITION EP05768904 2005-08-08 EP1780223A4 2009-03-11 KAWASHIMA MITSUNOBU; TAKASE AKI
A nonaqueous curable composition including a liquid radical polymeric monomer (a), an organic peroxide (b) and a powdered water-soluble reducing compound (c) with the powdered water-soluble reducing compound (c) dispersed in the liquid radical polymeric monomer (a) is provided. According to the nonaqueous curable composition of this invention, time necessary for adhesion can be secured, and high adhesive strength against a wetting material, and more particularly, a biological hard tissue such as a dentine can be attained, and thus, the present invention is extremely industrially valuable.
188 Knochenzementmischung und Röntgenkontrastmittel sowie Verfahren zu ihrer Herstellung EP07000986.5 2003-04-25 EP1782845B1 2008-12-17 Kühn, Klaus-Dieter
189 Knochenzement mit verbesserten mechanischen Eigenschaften und Verfahren zu seiner Herstellung EP03023419.9 2003-10-17 EP1430913B1 2008-05-14 Schilke, Frank, Dipl.-Chem.; Nies, Berthold, Dr.; Jeschke, Brigitte, Dr.; Koch, Matthias, Dr.; Kübelbeck, Armin, Dipl.-Ing.
190 Knochenzement mit verbesserten mechanischen Eigenschaften und Verfahren zu seiner Herstellung EP07090086.5 2003-10-17 EP1862187A3 2008-03-12 Schilke, Frank; Nies, Berthold; Jeschke, Brigitte; Koch, Matthias; Kübelbeck, Armin

Die Erfindung betrifft einen Knochenzement aus Polyacrylaten oder Polymethacrylaten, welcher ein festes Röntgenkontrastmittel umfasst, das durch Acrylatgruppen funktionalisiert ist und eine chemische Verbindung mit dem umgebenden Polymer des ausgehärteten Knochenzements eingehen kann. Weiterhin betrifft die Erfindung die Verwendung eines solchen Knochenzements zur Herstellung eines Arzneimittels zur Verankerung von Prothesenkomponenten im Knochen, zur Versteifung von Knochen, als Dübel von Knochenschrauben oder als Implantat zur Verankerung von Schrauben.

191 A POLYURETHANE BASED COMPOSITION FOR FILLING OR SHORT-CIRCUITING VASCULAR CAVITIES EP03773878.8 2003-10-30 EP1558299A1 2005-08-03 HUDAK, István
The invention is directed to the use of a polyurethane for preparing a composition or a kit usable for filling or short-circuiting vascular cavities, where the polyurethane used can be dissolved in a solvent or a solvent mixture mingling with body fluids.
192 Knochenzementmischung und Röntgenkontrastmittel sowie Verfahren zu ihrer Herstellung EP03009377.7 2003-04-25 EP1366774A1 2003-12-03 Kühn, Klaus-Dieter, Dr.

Beschrieben wird eine Knochenzementmischung, gebildet aus einer ein Röntgenkontrastmittel enthaltenden Polymerkomponente und einer Monomerkomponente, wobei das Röntgenkontrastmittel

  • a) als Polymer oder Copolymer mit daran chemisch gebundenen Verbindungen röntgenopaker Elemente ausgebildet ist oder
  • b) als im wesentlichen kugelförmige Polymer- oder Copolymerteilchen mit darin dispergierten röntgenopaken anorganischen Nanopartikeln der Teilchengröße 3-15 nm, hergestellt durch Polymerisation, bevorzugt Suspensionspolymerisation, in Gegenwart der Nanopartikel, wobei die Nanopartikel vollständig oder nahezu vollständig von dem (Co)polymermaterial bedeckt sind.

193 VASCULAR EMBOLIZING COMPOSITIONS COMPRISING ETHYL LACTATE AND METHODS FOR THEIR USE EP99933648.0 1999-07-02 EP1091724A1 2001-04-18 GREFF, Richard, J.
Disclosed are novel compositions for embolizing blood vessels which are particularly suited for treating vascular lesions via catheter delivery. In one embodiment, the compositions of this invention comprise a biocompatible polymer, ethyl lactate solvent and a biocompatible contrast agent.
194 ADHESIVE FOR SECURE TOPICAL ATTACHMENT TO THE SKIN AND COMFORTABLE REMOVAL EP97952541.7 1997-12-22 EP1023019A1 2000-08-02 CINELLI, Fabio; COLES, Peter; CORZANI, Italo
The present invention relates to disposable absorbent articles particularly sanitary napkins, pantiliners, adult incontinence products or sweat pads. In particular the present invention relates to such disposable absorbent articles which are worn by direct attachment to the skin of the wearer in the area were absorption of bodily liquids is desired.
195 ADHESIVE FOR SECURE TOPICAL ATTACHMENT TO THE SKIN AND COMFORTABLE REMOVAL EP97953322.0 1997-12-22 EP0948367A1 1999-10-13 CINELLI, Fabio; COLES, Peter; CORZANI, Italo
The present invention relates to topical adhesives for attachment to the skin. In particular the present invention relates to such topical adhesives which can be employed for attachment to the skin of protective articles, clothing, prosthesis, heat wraps, pads, and/or packs, e.g. for topical relief of pain or simply to provide warmth; cold wraps, hearing aids, protective face masks, ornamental articles, or eye wear but excluding absorbent articles. The topical adhesive provides secure attachment and is pleasing to the skin upon application, yet causes no discomfort upon removal. This is achieved by selecting the chemical composition and rheological characteristics of the topical adhesives.
196 ADHESIVE FOR APPLICATION OF FUNCTIONAL ARTICLES TO THE SKIN AND COMFORTABLE REMOVAL OF SUCH ARTICLES EP97952628.0 1997-12-22 EP0946213A1 1999-10-06 COLES, Peter; CINELLI, Fabio
The present invention relates to topical adhesives for attachment to the skin. In particular, the present invention relates to such topical adhesives which can be employed for application of functional articles to the skin, particularly for the adhesion of functional articles or the improvement of the function of such articles. Functional articles in this context are cosmetic or pharmaceutical delivery articles which provide a substance to the skin such as skin treatment substances, creams, lotions, hormones, vitamins, deodorants, or drugs; alternatively, cosmetic or pharmaceutical delivery articles can also provide a substance to emanate away from the skin such as insecticides, inhalation drugs, or perfumes; further, the adhesive of the present invention can also be used in functional articles which are not attached to the skin but as a component in articles which require a high residence time on the skin such as decorative cosmetics (lipstick, eye colors, stage make-up) or cleaning article (hand cleaner, face mask, hygienic cleanser especially for pores). The topical adhesive provides secure attachment or increased residence time and is pleasing to the skin upon application, yet causes no discomfort upon removal. This is achieved by selecting the chemical composition and rheological characteristics of the topical adhesives.
197 Disposable absorbent article for topical adhesive attachment to the skin of a wearer EP96120738.8 1996-12-23 EP0850619A1 1998-07-01 Corzani, Italo; Romano, Mario

The present invention relates to disposable absorbent articles particularly sanitary napkins, pantiliners, adult incontinence products or sweat pads. In particular the present invention relates to such disposable absorbent articles which are worn by direct attachment to the skin of the wearer in the area were absorption of bodily liquids is desired.

198 Intraocular lens and methods for its preparation EP89113981.8 1989-07-28 EP0353651A1 1990-02-07 Wichterle, Itto; Michalek, Jiri, Dipl.-Ing.; Vacik, Jiri CSc, Dipl.-Ing.

An intraocular lens consisting of a core of a polymer with a refractive index of 1.37 to 1.6 with the shape of a biconvex or plano-convex lens and a peripheral case covering one surface of the core either completely or only on its circum­ference and the other surface to a distance of atmost 2 mm from the core axis is produced by placing the core on a plane or rotationally symmetric curved casting surface, overcasting it with a monomer mixture in order to wet the lower surface of the core either completely or only in its circumferential part and the upper surface to a distance of atmost 2 mm from the core axis and then polymerizing the monomer mixture by thermal or photochemical polymerization.

199 IMPLANTABLE OBJECTS, GUIDING DEVICES, AND METHODS OF USE THEREOF US15778520 2016-11-23 US20180344894A1 2018-12-06 George W. Kay; Brian J. Hess
Embodiments of the disclosure relate to implantable objects and guiding devices, as well as recipient site preparation instruments, bone-implantable materials, and methods of fabrication and use thereof.
200 Skin Closure Devices with Self-forming Exudate Drainage Channels US15496389 2017-04-25 US20180303967A1 2018-10-25 Julian Quintero; Leo B. Kriksunov
A device for application onto wounds with a liquid rapidly polymerizable adhesive for forming skin closure systems, comprising a thin flexible flat porous tape, preferably a mesh, elongated along a longitudinal axis and having a lower side or wound-facing side and an opposing upper side, a periphery, and central portion in immediate vicinity of the axis; said tape coated or impregnated with an initiator or accelerator of polymerization; said tape having a plurality of elongated traces of soluble pressure sensitive adhesive (PSA) disposed on the wound-facing side; said traces covering from about 3% to about 50% of area of said tape and extending from the periphery to the central portion of said tape.
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