| 序号 | 专利名 | 申请号 | 申请日 | 公开（公告）号 | 公开（公告）日 | 发明人 |
|---|---|---|---|---|---|---|
| 1 | 一种可载药聚乙烯醇洗脱微球的制备方法 | CN201611137420.X | 2016-12-12 | CN106693040A | 2017-05-24 | 倪才华; 曹元龙; 张丽萍; 石刚; 桑欣欣 |
| 本发明公布一种可载药聚乙烯醇洗脱微球的制备方法，涉及生物医药材料领域。制备包括以下步骤：(1)配制一定浓度的聚乙烯醇水溶液，然后加入2‑丙烯酰胺‑2‑甲基丙磺酸、N,N‑亚甲基双丙烯酰胺，磁力搅拌均匀。(2)以过硫酸盐与亚硫酸盐为氧化‑还原引发体系，戊二醛为固化剂，通过反相微悬浮交联方法，制备出粒径在100～700um的改性聚乙烯醇微球，即可载药聚乙烯醇洗脱微球。由于微球带有大量的磺酸基团，可有效地负载含正电荷药物例如盐酸阿霉素、用做血管栓塞剂。 | ||||||
| 2 | Glass polycarboxylate cement | JP2010514124 | 2008-07-02 | JP2010532338A | 2010-10-07 | スティーブンス，モリー，モラグ; ヒル，ロバート，グラハム |
| 本発明はポリカルボキシラートセメントの作製に用いるためのガラス組成物およびそれらのガラスを含有するポリカルボキシラートセメントに関し、ここでガラスがＳｉＯ ２およびＭｇＯを含有し、ＳｉＯ ２のモルパーセントが６０％を超えず、ＭｇＯのモルパーセントが２０％より大きい。 | ||||||
| 3 | Paste-type dental cement | JP2008233701 | 2008-09-11 | JP2010064989A | 2010-03-25 | KATO KATSUTO; YARIMIZU HIDEKI |
| PROBLEM TO BE SOLVED: To provide paste-type dental cement which can obtain dental cement suited for temporary adhering or temporary filling. SOLUTION: The paste-type dental cement comprises phosphoric acid and/or a polymer of an α,β-unsaturated carboxylic acid, an oxide powder reactive with the phosphoric acid and/or the polymer of an α,β-unsaturated carboxylic acid, and water and further includes a liquid not reacting with the oxide powder reactive with the phosphoric acid and/or the polymer of an α,β-unsaturated carboxylic acid. COPYRIGHT: (C)2010,JPO&INPIT | ||||||
| 4 | ALUMINOUS CEMENT-BASED COMPOSITION FOR APPLICATION IN ENDODONTICS AND CEMENTITIOUS PRODUCT OBTAINED THEREOF | EP08855244 | 2008-11-27 | EP2224895A4 | 2013-09-11 | PANDOLFELLI VICTOR CARLOS; OLIVEIRA IVONE REGINA DE; JACOBOVITZ MARCOS; ROSSETTO HEBERT LUIS |
| The present invention provides a composition based on calcium aluminate cement (CAC) for application in endodontics, comprising: (a) a cement—Al2O3 (>68.5 wt %), CaO (<31 wt %), SiO2 (0.3-0.8 wt %), MgO (0.4-0.5 wt %), and Fe2O3 (<0.3 wt %); (b) additives: dispersant at a content of 0.4 to 0.8% by weight of the cement, a plasticizer at a content of 2.0 to 4.0% by weight of the cement, and a radiopaque agent at a content of 20 to 35% by weight of the cement; and (c) water, wherein water/cement ratio lies in the range of 0.19-0.24 in the presence of additives. Cementitious product obtained thereof, after setting time, is also disclosed and characterized by enhanced properties when compared to the most used commercial repair cement, MTA. | ||||||
| 5 | ALUMINOUS CEMENT-BASED COMPOSITION FOR APPLICATION IN ENDODONTICS AND CEMENTITIOUS PRODUCT OBTAINED THEREOF | EP08855244.3 | 2008-11-27 | EP2224895A2 | 2010-09-08 | PANDOLFELLI, Victor Carlos; OLIVEIRA, Ivone Regina de; JACOBOVITZ, Marcos; ROSSETTO, Hebert Luis |
| The present invention provides a composition based on calcium aluminate cement (CAC) for application in endodontics, comprising: (a) a cement—Al2O3 (>68.5 wt %), CaO (<31 wt %), SiO2 (0.3-0.8 wt %), MgO (0.4-0.5 wt %), and Fe2O3 (<0.3 wt %); (b) additives: dispersant at a content of 0.4 to 0.8% by weight of the cement, a plasticizer at a content of 2.0 to 4.0% by weight of the cement, and a radiopaque agent at a content of 20 to 35% by weight of the cement; and (c) water, wherein water/cement ratio lies in the range of 0.19-0.24 in the presence of additives. Cementitious product obtained thereof, after setting time, is also disclosed and characterized by enhanced properties when compared to the most used commercial repair cement, MTA. | ||||||
| 6 | GERMANIUM-BASED GLASS POLYALKENOATE CEMENT | US15136728 | 2016-04-22 | US20160235884A1 | 2016-08-18 | Victoria DICKINSON; Daniel BOYD; Brett DICKEY; Sharon KEHOE |
| Disclosed herein are compositions and methods for making germanium-based glass polyalkenoate cements. Also disclosed are methods for their use as bone cements for bone augmentation procedures. | ||||||
| 7 | A NOVEL GLASS-IONOMER CEMENT | US14758602 | 2013-12-20 | US20150367023A1 | 2015-12-24 | Cheryl MILLER; Paul V. HATTON; Felora MIRVAKILY |
| A novel, glass-ionomer cement (GIC), which is preferably bioactive, and which is both trivalent metal cation-free and magnesium-free, comprising: (i) a glass composition which is both trivalent metal cation-free and magnesium-free (and is preferably bioactive), and (ii) a polyacid. | ||||||
| 8 | RESTORATIVE MATERIALS | US13981421 | 2012-01-24 | US20140053758A1 | 2014-02-27 | John Nicholson; Samantha Booth |
| The present invention relates to restorative materials, in particular to glass-ionomer cements. More particularly, the present invention relates to glass-ionomer cements having particular utility in the repair of human hard tissue, in particular as dental restorative materials and in orthopaedic surgery. We describe a composition comprising a mixture of a glass ionomer cement and zinc phosphate. Preferably, the composition comprise from 40 to 95% by weight of glass ionomer cement and from to 60% by weight of zinc phosphate. The present invention also provides a powdered composition comprising a fluorosilicate glass and deactivated zinc oxide. Such that the zinc phosphate is formed in sith by reaction between the zinc oxide and phosphoric acid. | ||||||
| 9 | Glass Polycarboxylate Cements | US12667548 | 2008-07-02 | US20110009511A1 | 2011-01-13 | Robert Graham Hill; Molly Morag Stevens |
| The present invention relates to glass compositions for use in formation of polycarboxylate cements and polycarboxylate cements comprising these glasses, wherein the glasses comprise SiO2 and MgO, with a molar percentage of SiO2 not exceeding 60% and a molar percentage of MgO being greater than 20%. | ||||||
| 10 | PASTE-TYPE DENTAL CEMENT | US12553344 | 2009-09-03 | US20100063176A1 | 2010-03-11 | Katsuhito KATO; Hideki Yarimizu |
| To provide a paste-type dental cement capable of being used properly for temporary adhering or temporary filling, a paste-type dental cement, which comprises a phosphoric acid and/or a polymer of α-β unsaturated carboxylic acid, an oxide powder capable of reacting with the phosphoric acid and/or the polymer of α-β unsaturated carboxylic acid, and a water, further includes a liquid not reacting with the oxide powder. | ||||||
| 11 | Process for the preparation of a composition comprising a multi-branched compound | JP2012518817 | 2010-07-06 | JP2012532166A | 2012-12-13 | イー． クリー，ヨアヒム; リッター，ヘルムート; ポーレ，スフェン; ベツシュナ，エラ; エルスナー，オリバー |
| 多分岐高分子化合物を含む組成物の調製プロセスであって、下記式（Ｉ）：ＡＲ（Ｂ） ｎ （式中、Ａ及びＢは、官能基であり、Ｒは、１つ又は複数のチオエーテル基を含有する（ｎ＋１）価の有機基であり、ｎは、少なくとも２の整数であり、Ａがアミノ基又はヒドロキシル基であり、かつＢがカルボン酸基又はそのエステル若しくは無水物であることを特徴とする）を有する１つ又は複数の化合物を含む混合物を、ＡがＢと反応して、結合アミド基を形成する一方で、ＡはＡとは反応せず、かつＢはＢとは反応しない反応条件下で反応させる工程を含む、多分岐高分子化合物を含む組成物の調製プロセス。 | ||||||
| 12 | 化学硬化型のグラスアイオノマーセメント | JP2008513227 | 2007-04-24 | JPWO2007125930A1 | 2009-09-10 | 憲司 有田 |
| 【課題】この発明により、光硬化型のグラスアイオノマーセメント(GIC)の諸欠点をすべて解消すると共に、機械的強度が光硬化型のそれに比べ優るも劣らず、しかも、GIC本来の特徴と利点を保有する高品質の安全な化学硬化型GICを提供すること。【解決手段】本発明の化学硬化型のグラスアイオノマーセメントは、平均直径を0.6μm以上であって100μm未満とし、多孔質として比表面積を大きくしている微粒子状のハイドロキシアパタイトを添加混合している。【選択図】図2 | ||||||
| 13 | The dental paste glass ionomer cement composition | JP2001383273 | 2001-12-17 | JP4132806B2 | 2008-08-13 | 伸一 加藤; 恵三 小林 |
| 14 | Chemical curing type of glass ionomer cement | JP2008513227 | 2007-04-24 | JP5071941B2 | 2012-11-14 | 憲司 有田 |
| 15 | Cement for sealer | JP2008235095 | 2008-09-12 | JP2010065006A | 2010-03-25 | TANAKA KOJI; YARIMIZU HIDEKI; NAKASEKO HISASHI |
| PROBLEM TO BE SOLVED: To provide a dental glass ionomer cement for a sealer to be used for sealing a gap between a gutta-percha point filled in a root canal in a dental root canal treatment and a root canal wall, with a prolonged setting time and with sufficient setting property even in a root canal having much water content. SOLUTION: The dental cement for the sealer includes a polymer of an α-β unsaturated carboxylic acid, oxide powder reactive with the polymer of the α-β unsaturated carboxylic acid, and water, and further includes an organic acid salt of a metal selected from Mg, Ca and Sr and/or a hydroxide of a metal selected from Mg, Ca and Sr. COPYRIGHT: (C)2010,JPO&INPIT | ||||||
| 16 | Pasty glass ionomer cement composition for dental use | JP2001383273 | 2001-12-17 | JP2003183112A | 2003-07-03 | KOBAYASHI KEIZO; KATO SHINICHI |
| PROBLEM TO BE SOLVED: To obtain a pasty glass ionomer cement composition for dental use which, while retaining excellent characteristics inherent in a glass ionomer cement, has a good handleability and does not contain a polymerizable monomer. SOLUTION: This pasty glass ionomer cement composition comprises a first paste and a second paste. The first paste comprises 30-70 wt.% α,β-unsaturated carboxylic acid polymer and 30-70 wt.% water, and the second paste comprises 50-85 wt.% fluoroaluminosilicate glass powder, 0.005-1 wt.% water-soluble thickener, and the balance water. COPYRIGHT: (C)2003,JPO | ||||||
| 17 | Apparatus and method of spinal implant and fusion | US15220795 | 2016-07-27 | US09861496B2 | 2018-01-09 | Jeffrey B. Kleiner |
| An apparatus and method of performing a minimally invasive posterior spine fusion. More specifically an apparatus with a handle and a forked head on the distal end of the handle is used to grasp implant material and introduce the material to an implant site. The shaft of the apparatus is shaped so as to allow the affixation of a drill guide and drill while simultaneously holding the implant material in the implant site. After removal of the boring tools and assembly of the fusing element, the apparatus can be selectively removed from the implant site. A method of achieving facet joint fusion with near simultaneous fixation is also disclosed. | ||||||
| 18 | Apparatus and Method of Spinal Implant and Fusion | US15220795 | 2016-07-27 | US20170027713A1 | 2017-02-02 | Jeffrey B. Kleiner |
| An apparatus and method of performing a minimally invasive posterior spine fusion. More specifically an apparatus with a handle and a forked head on the distal end of the handle is used to grasp implant material and introduce the material to an implant site. The shaft of the apparatus is shaped so as to allow the affixation of a drill guide and drill while simultaneously holding the implant material in the implant site. After removal of the boring tools and assembly of the fusing element, the apparatus can be selectively removed from the implant site. A method of achieving facet joint fusion with near simultaneous fixation is also disclosed. | ||||||
| 19 | Germanium-based glass polyalkenoate cement | US15136728 | 2016-04-22 | US09555156B2 | 2017-01-31 | Victoria Dickinson; Daniel Boyd; Brett Dickey; Sharon Kehoe |
| Disclosed herein are compositions and methods for making germanium-based glass polyalkenoate cements. Also disclosed are methods for their use as bone cements for bone augmentation procedures. | ||||||
| 20 | Germanium-based glass polyalkenoate cement | US14397965 | 2013-05-03 | US09352069B2 | 2016-05-31 | Victoria Dickinson; Daniel Boyd; Brett Dickey; Sharon Kehoe |
| Disclosed herein are compositions and methods for making germanium-based glass polyalkenoate cements. Also disclosed are methods for their use as bone cements for bone augmentation procedures. | ||||||
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