子分类：
| 序号 | 专利名 | 申请号 | 申请日 | 公开（公告）号 | 公开（公告）日 | 发明人 |
|---|---|---|---|---|---|---|
| 41 | ポリマーとポリマーの製造法 | JP2003552828 | 2002-10-30 | JPWO2003051952A1 | 2005-04-28 | 武久 松田; 哲雄 伊藤; 大隅 辰也; 辰也 大隅 |
| 本発明は、湿潤接着強度(耐水接着強度)が高い医療用接着剤用として最適なポリマーを提供することを目的とする。硬化皮膜を形成し得る医療用接着剤に用いられるポリマーであって、37℃における粘度が0.5〜2,000Pa・sであり、かつ、飽和吸水量が0.2〜5ml/gであることを特徴とするポリマーを用いる。このポリマーの初期吸水速度は0.01〜0.5ml/g・minが好ましく、また、硬化皮膜の湿潤伸び率は100〜1,500%が好ましく、硬化皮膜の湿潤100%モデュラスは0.01〜10MPaが好ましい。また、このポリマーはオキシエチレン基を含有してなり、オキシエチレン基の含有量がポリマーの重量に基づいて30〜100重量%であることが好ましい。 | ||||||
| 42 | Cement for bone having improved mechanical physical property and production method thereof | JP2003420445 | 2003-12-18 | JP2004202228A | 2004-07-22 | SCHILKE FRANK; NIES BERTHOLD DR; JESCHKE BRIGITTE; KOCH MATTHIAS; KUEBELBECK ARMIN |
| <P>PROBLEM TO BE SOLVED: To provide a cement for a bone, in which elimination of an X-ray shadow agent from a matrix is inhibited, and a production method thereof. <P>SOLUTION: The X-ray shadowing agent is precoated with a melamine-formaldehyde resin and is functionalized with a (meth)acryl group. The cement for a bone obtained can be employed to fix a prosthesis constituent to a bone or to fix the bone and furthermore can also be employed as a plug for fixing a screw for a bone or as a transplant stripe for fixing the screw. <P>COPYRIGHT: (C)2004,JPO&NCIPI | ||||||
| 43 | Bone cement mixture, x-ray contrast agent, manufacturing method thereof, and use of polymer and copolymer including barium zirconium and another element as x-ray contrast agent | JP2003149663 | 2003-05-27 | JP2003339850A | 2003-12-02 | KUEHN KLAUS-DIETER |
| <P>PROBLEM TO BE SOLVED: To provide an improved X-ray contrast agent, a bone cement mixture, an X-ray contrast agent-containing bone cement, and manufacturing methods of the X-ray contrast agent and the bone cement. <P>SOLUTION: This X-ray contract agent is formed as (a) a polymer or a copolymer including a compound of chemically bonded X-ray impermeable element, or (b) substantially spherical polymer particles or spherical copolymer particles having X-ray impermeable dispersed-inorganic nano-particles of 3-15 nm particle size. The polymer particles or the copolymer particles are prepared in the presence of nano-particles by polymerization, preferably, by suspension polymerization. Here, the nano-particles are completely or almost completely covered by a polymer material. <P>COPYRIGHT: (C)2004,JPO | ||||||
| 44 | Adhesives for secure topical attachment and comfortable removal of the skin | JP52906198 | 1997-12-22 | JP2001508329A | 2001-06-26 | コールス、ピーター; シネリ、ファビオ |
| (57)【要約】 本発明は、皮膚に取り付けるための局所用接着剤に関する。 特に、本発明は、吸収性物品を除き、保護物品、衣類、プロテーゼ、ヒートラップ、例えば苦痛を局所的に軽減する或いは単に温かさを提供するためのパッド及び／またはパック；コールドラップ、補聴器、保護用フェイスマスク、装飾用物品、或いはアイウエアを皮膚に取り付けるために用いられ得る局所用接着剤に関する。 その局所用接着剤は、確実な取り付けを提供し、適用の際に皮膚に心地よく、除去の際に不快感を生じさせない。 これは、局所用接着剤の化学組成及び流動学的特性を選択することにより達成される。 | ||||||
| 45 | Adhesive for application to the skin of a functional article and comfortable detachment of such articles | JP52896398 | 1997-12-22 | JP2001507962A | 2001-06-19 | コールス、ピーター; コルツァーニ、イタロ; チネリ、ファビオ |
| (57)【要約】 本発明は、皮膚に接着するための局所用接着剤に関する。 特に、本発明は、皮膚に機能的物品を適用するために、特に機能性物品の接着またはこのような物品の機能の改良のために使用され得るこのような局所用接着剤に関する。 この背景における機能的物品は、皮膚のトリートメント物質、クリーム、ローション、ホルモン、ビタミン、防臭剤、または薬品等の物質を皮膚に提供する化粧品または薬剤を送達する物質である。 あるいは、化粧品または薬剤を送達する物質は、防虫剤、吸入薬、または香水等の皮膚から離れて発散する物質を提供し、さらに、本発明の接着剤は、皮膚に接着されないが、例えば装飾的化粧品（リップスティック、アイカラー、舞台化粧）または洗浄物品（ハンドクリーナー、フェイスマスク、特に毛穴用の衛生的クリーナー）等を皮膚上に耐久させる時間が高いことが要求される物品の成分として機能的物品に使用され得る。 局所用接着剤は、不快感を生じることなく確実な接着を提供し、適用時に皮膚に気持ちが良く、除去時に、皮膚上の接着剤残留物のレベルが低い。 このことは、特に局所用接着剤の弾性係数Ｇ' 37と粘性係数Ｇ” 37との関係について局所用接着剤の化学的組成及び流動学的特性を選択することにより達成される。 | ||||||
| 46 | Adhesives for secure topical attachment and comfortable removal of the skin | JP52906098 | 1997-12-22 | JP2000505713A | 2000-05-16 | コルツァーニ、イタロ; ロマノ、マリオ |
| (57)【要約】 本発明は、皮膚に取り付けるための局所用接着剤に関する。 特に、本発明は、身体液の吸収が望まれる領域で皮膚に取り付けるのに用いられ得る局所用接着剤に関する。 その局所用接着剤は、確実な取り付けを提供し、適用の際に皮膚に心地よく、除去の際に不快感を生じさせない。 これは、局所用接着剤の化学組成及び流動学的特性を選択することにより達成される。 | ||||||
| 47 | Artificially transplanted lens | JP6472876 | 1976-06-04 | JPS51151149A | 1976-12-25 | HANSU YOAHIMU SHIYUREEGERU |
| The lens has a lens body (11) of a homogeneous, transparent plastic provided with mountings engaging over the pupillary edge of the iris for fastening on the iris. The lens body and its mountings are made of an elastomeric silicone rubber or silicone resin the specific gravity of which approximately corresponds to that of the aqueous humour or is slightly above that. Two annular discs (15, 16; 15', 16') between which an annular space (19), which widens toward the outside and is hollowed in the region adjoining the lens body, for accommodation of the edge of the iris sit on the circumferential area (14) of the central lens body. |
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| 48 | Polymeric fibers having tissue reactive members | US13192007 | 2011-07-27 | US09987297B2 | 2018-06-05 | Sébastien Ladet |
| A method for bonding a polymeric fiber to tissue is provided which includes providing a polymeric fiber having a plurality of tissue reactive members linked to a surface of the fiber via a specific binding pair, and contacting the polymeric fiber to biological tissue, to covalently bond the fiber to the tissue. | ||||||
| 49 | OSTOMY DEVICE | US15542667 | 2016-02-02 | US20180008451A1 | 2018-01-11 | Esben STROEBECH |
| Disclosed is an ostomy device with an adhesive wafer for attachment to a skin surface of a user and a collecting bag for collecting output from a stoma. The collecting bag is connected to the adhesive wafer, and the adhesive wafer has a through-going hole for accommodating the stoma of the user. The adhesive wafer includes a backing layer, a first switchable adhesive composition (11), a second absorbent adhesive composition (12), and a release liner. | ||||||
| 50 | ANTISEPTIC POLYMETHYLMETHACRYLATE BONE CEMENT | US15637456 | 2017-06-29 | US20180000984A1 | 2018-01-04 | Sebastian VOGT; Lorena CALDERÓN ORTIZ |
| An antiseptic composition for use as bone cement, in particular an antiseptic polymethylmethacrylate bone cement. The composition can be cured and comprises a pharmacologically tolerable salt of a monoperoxy dicarboxylic acid, whereby the salt of the monoperoxy dicarboxylic acid can be dissolved from the composition in the presence of water. Preferably, the salt of the monoperoxy dicarboxylic acid in the composition is used in the form of a powder, whereby the powder has a mean particle size of not more than 250 μm. Preferably, the salt of the monoperoxy dicarboxylic acid, in solution at room temperature, is not degraded within 5 min by the catalase enzyme. | ||||||
| 51 | ELECTROACTIVE BIOADHESIVE COMPOSITIONS | US15111567 | 2015-01-14 | US20160331861A1 | 2016-11-17 | Terry W.J. STEELE; Daniel MANDLER |
| The present invention relates to electrochemically initiated bioadhesive compositions comprising biocompatible polymers containing derivatives of diazonium, arylsulfonium, or diaryliodonium in general, and to their use in tissue fixation, in particular. | ||||||
| 52 | Method and device for female urinary incontinence | US14207259 | 2014-03-12 | US09408943B2 | 2016-08-09 | Cora St. Anne |
| A method and device for use in stress female urinary incontinence. A small, flexible adhesive patch is applied directly to the clitoris of a person suffering from stress female urinary incontinence. The adhesive is of a type sufficient to stimulate the mechanoreceptors located in the clitoris whereby to inhibit discharge from the bladder. The patch is formed of a backing sheet of an impervious material containing adhesive on one side. A release liner prevents the adhesive from drying out. | ||||||
| 53 | GEL-FORMING SYSTEM FOR REMOVING URINARY CALCULI AND FRAGMENTS THEREOF | US14786810 | 2013-08-22 | US20160067373A1 | 2016-03-10 | Ingo GRUNWALD; Katharina RICHTER; Arkadiusz MIERNIK; Martin SCHOENTHALER |
| Primarily described are gel-forming systems, consisting of or comprising a composition (A), comprising one or several cationically crosslinkable polymer(s), and a composition (B), comprising one or several crosslinking agent(s) for crosslinking the cationically crosslinkable polymer(s) for use in a method for removing urinary calculi and/or fragments thereof, more particularly kidney stones and/or fragments thereof, from a region of the urinary tract, more particularly a kidney, that contains urinary calculi and/or fragments thereof, more particularly kidney stones and/or fragments thereof, that are to be removed, with the following steps: (i) providing the compositions (A) and (B), (ii) introducing the compositions (A) and (B) into a region of the urinary tract, more particularly the kidney, that contains urinary calculi and/or fragments thereof, more particularly kidney stones and/or fragments thereof, that are to be removed, under conditions enabling crosslinking of the cationically crosslinkable polymer(s) upon contact of composition (A) with composition (B) so that a crosslinked gel is formed that partly or fully surrounds the urinary calculi and/or fragments thereof, more particularly kidney stones and/or fragments thereof, that are to be removed, (iii) removing the crosslinked gel together with the urinary calculi and/or fragments thereof, more particularly kidney stones and/or fragments thereof, that are surrounded by it from the urinary tract, more particularly the kidney. | ||||||
| 54 | APPARATUS AND METHODS FOR SEALING A VASCULAR PUNCTURE | US14276989 | 2014-05-13 | US20140249575A1 | 2014-09-04 | Andreas Mylonakis; Jacky Au-Yeung; Florencia Lim |
| A sealant for sealing a puncture through tissue includes a first section, e.g., formed from freeze-dried hydrogel, and a second section extending from the distal end. The second section may be formed from PEG-precursors including PEG-ester and PEG-amine, e.g., in an equivalent ratio of active group sites of PEG-ester/PEG-amine greater than one-to-one, e.g., such that excess esters may provide faster activation upon contact with physiological fluids and enhance adhesion of the sealant within a puncture. At least some of the precursors remain in an unreactive state until exposed to an aqueous physiological environment, e.g., within a puncture, whereupon the precursors undergo in-situ cross-linking to provide adhesion to tissue adjacent the puncture. For example, the PEG-amine precursors may include the free amine form and the salt form. The free amine form at least partially cross-links with the PEG-ester and the salt form remains in the unreactive state in the sealant before introduction into the puncture. | ||||||
| 55 | METHOD AND DEVICE FOR FEMALE URINARY INCONTINENCE | US14207259 | 2014-03-12 | US20140194550A1 | 2014-07-10 | Cora St. Anne |
| A method and device for use in stress female urinary incontinence. A small, flexible adhesive patch is applied directly to the clitoris of a person suffering from stress female urinary incontinence. The adhesive is of a type sufficient to stimulate the mechanoreceptors located in the clitoris whereby to inhibit discharge from the bladder. The patch is formed of a backing sheet of an impervious material containing adhesive on one side. A release liner prevents the adhesive from drying out. | ||||||
| 56 | Organophosphorous and multivalent metal compound compositions and methods | US13469806 | 2012-05-11 | US08765189B2 | 2014-07-01 | Venkat R. Garigapati; Kevor S. TenHuisen |
| Compositions and methods of their use to adhere a variety of materials together are disclosed herein. The compositions include at least multivalent metal compound, an effective amount of a compound that is structurally similar to phosphoserine, and can be mixed with an aqueous solution. The compositions provide adhesive and cohesive strength in both wet and dry environments which exhibit bond strength upon curing with the possible usage as bone cement for bone filler applications. | ||||||
| 57 | Injectable biomaterial | US13254617 | 2010-03-02 | US08673264B2 | 2014-03-18 | Minh Tam Baylatry; Anouk Bisdorf-Bresson; Denis Labarre; Alexandre Laurent; Laurence Moine; Jean-Pierre Saint-Maurice; Khelil Slimani; Michel Wassef |
| An injectable biomaterial containing a non-aqueous solvent suitable for injection to a human being and nanoparticles made of a polymer that is insoluble in water and insoluble in the non-aqueous solvent, in which the nanoparticles are loaded with a drug or a biological agent. The injectable biomaterial is suitable for occluding normal or malformative blood vessels or non-circulating cavities, or for necrosing tumors. | ||||||
| 58 | Devices and methods for treating vascular malformations | US13114635 | 2011-05-24 | US08597320B2 | 2013-12-03 | Ivan Sepetka; Martin S. Dieck; Ryan Pierce; Maria Aboytes; Son Gia |
| A method of filling an aneurysm is described which includes the step of advancing a device through a patient's vascular system to an aneurysm and positioning the device within the aneurysm. The device has a closed mesh structure forming by a plurality of flexible filaments. The device also has a proximal collar and a distal collar with the flexible filaments extending therebetween. The closed mesh structure is movable from a collapsed configuration to an expanded configuration. | ||||||
| 59 | Setting time indicator for acrylic bone cement | US11653654 | 2007-01-16 | US08415406B2 | 2013-04-09 | Shulin He; Matthew P. Poggie |
| A bone cement has a liquid acrylic monomer component, a powdered acrylic polymer component and yellowish beta-carotene (Pro-vitamin A) mixed into one of the liquid or powdered component and FDC blue No. 2 Lake powder mixed into the powdered component. The beta-carotene and FDC blue adds a greenish (yellow plus blue) color to the combined liquid and powdered component. The yellowish color disappears on setting of the bone cement leaving the cement blue. | ||||||
| 60 | ORGANOPHOSPHOROUS & MULTIVALENT METAL COMPOUND COMPOSITIONS & METHODS | US13469806 | 2012-05-11 | US20120288446A1 | 2012-11-15 | Venkat R. Garigapati; Kevor S. TenHuisen |
| Compositions and methods of their use to adhere a variety of materials together are disclosed herein. The compositions include at least multivalent metal compound, an effective amount of a compound that is structurally similar to phosphoserine, and can be mixed with an aqueous solution. The compositions provide adhesive and cohesive strength in both wet and dry environments which exhibit bond strength upon curing with the possible usage as bone cement for bone filler applications. | ||||||
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