61 |
JPS62500590A - |
JP50482385 |
1985-10-24 |
JPS62500590A |
1987-03-12 |
|
A sulfurized composition prepared by sulfurizing a mixture of at least one terpene and at least one other olefinic compound is described. More particularly, sulfurized compositions prepared by sulfurizing a mixture of pine oil and at least one other olefinic compound are described. Such sulfurized compositions are useful as lubricant additive compositions, and more particularly, as additive compositions in industrial and gear lubricants. The compositions when added to lubricants provide lubricants which exhibit improved antioxidant characteristics, nitrile seal compatibility and acceptable color characteristics. |
62 |
JPS6028878B2 - |
JP16037676 |
1976-12-29 |
JPS6028878B2 |
1985-07-06 |
HORI TAKASHI; HAYASHIDA SUETO |
|
63 |
JPS5617342B2 - |
JP10834673 |
1973-09-26 |
JPS5617342B2 |
1981-04-22 |
|
|
64 |
JPS4955636A - |
JP7449573 |
1973-07-03 |
JPS4955636A |
1974-05-30 |
|
|
65 |
Mercaptosilane |
JP2006012372 |
2006-01-20 |
JP4921799B2 |
2012-04-25 |
ハッセ アンドレ; クロックマン オリバー; コルト カルステン; アルベルト フィリップ; ピーター ライムント |
|
66 |
Compound and method for inhibition of expression of vcam-1 |
JP2006116322 |
2006-04-20 |
JP2006265257A |
2006-10-05 |
SOMERS PATRICIA K; HOONG LEE K; MENG CHARLES Q |
<P>PROBLEM TO BE SOLVED: To provide a method and a composition for the inhibition of the expression of VCAM-1 (vascular cell adhesion molecule 1) and for the treatment of diseases mediated by VCAM-1, including cardiovascular and inflammatory diseases. <P>SOLUTION: The compound of general formula (II) [wherein, Ra, Rb, Rc and Rd are each an alkyl or an aryl; Z is hydrogen, an alkyl, an alkenyl, an alkynyl, a hydrocarbon group or -C(O)-R], the salt thereof acceptable as a medicament, and the medicament composition are provided. <P>COPYRIGHT: (C)2007,JPO&INPIT |
67 |
2-alkyl-cysteine, 2-synthesis of (hydroxylated) -4-alkyl-thiazoline-4-carboxylic acids and their derivatives |
JP2004505355 |
2003-05-15 |
JP2005538950A |
2005-12-22 |
ウォルステンホーム−ホッグ,ポール; グルジャー,ムクンド,ケイ.; コルゲーデ,ムクンド,エス.; シェリアン,ジョゼフ; ジミー,レイモンド,エイチ.; チャンダ,バヌ,エム.; マクドネル,ピーター,ディー.; マスカー,スニル,ブイ.; モハパトラ,デデンダラ,ケイ. |
本発明は、2-アルキルシステイン誘導体の調製方法を提供し、その多くは立体選択的に行われうる。 本発明はまた、デスフェリチオシンに関するイオンキレート剤のクラス(全てがチアゾリン環を含む)の調製方法を開示し、これらのイオンキレート剤の例は、4,5-ジヒドロ-2-(2,4-ジヒドロキシフェニル)-4-メチル-チアゾール-4-カルボン酸等の4,5-ジヒドロ-2-(2,4-ジヒドロキシフェニル)-4-アルキル-チアゾール-4-カルボン酸である。 |
68 |
Synthesis of benzonitrile and benzimidate |
JP2004505315 |
2003-05-15 |
JP2005525427A |
2005-08-25 |
グルジャー,ムクンド,ケイ.; コルゲーデ,ムクンド,エス.; シェリアン,ジョゼフ |
ベンゾニトライトおよびベンズイミデートは、典型的に市販されていない重要な中間体および開始材料である。 本発明は、2,4-ジヒドロキシ安息香酸からおよび2,4-ジヒドロキシベンズアルデヒドからの2,4-ジヒドロキシベンゾニトリルならびにそのエーテルおよびジエーテルの容易な合成を開示する。 さらに、本発明は、置換安息香酸から置換ベンズイミデートを調製する方法を開示する。 本発明はまた、デスフェリチオシンに関連する鉄キレート化剤のクラス(その全てがチアゾリン環を含む)を調製する方法を開示する。 本方法において、2,4-ジヒドロキシベンゾニトリルまたはアルキル2,4-ジヒドロキシベンゾニトリルまたはアルキル2,4-ジヒドロキシベンズイミデートは、(S)-2-メチルシステインで縮合される。 |
69 |
It is useful as nitric oxide synthase inhibitors halogenated Amijinoamino acid derivative |
JP2000535621 |
1999-03-04 |
JP2002506056A |
2002-02-26 |
ケイ アワスティ,アリク; キース ウェバー,アール; ピー スパングラー,デール; ツィンバロフ,ソフヤ; ヴィ トス,ミハリー; エイ バーグマニス,アリジャ; ジェイ ハーゲン,ティモシー; アン ハリナン,イー; ダブリュ,ジュニア ハンセン,ドナルド; エス ピッツェル,バーネット |
(57)【要約】 下記式(I)又はその薬剤学的に許容し得る塩の、酸化窒素シンターゼ阻害剤として有用なハロゲン化アミジノアミノ酸誘導体を開示し、全ての置換基は明細書中に記載する。 【化36】 |
70 |
Probucol monoesters for the treatment of cardiovascular and inflammatory diseases |
JP54949898 |
1998-05-14 |
JP2001524986A |
2001-12-04 |
ソマーズ,パトリシア・ケイ |
(57)【要約】 本発明は、VCAM−1の阻害、具体的には、アテローム性動脈硬化症を含む心血管疾患または炎症性疾患を治療するための、有効量のプロブコールモノエステルの投与を含む方法および組成物である。 |
71 |
Hiv matrix protein tyrosine 29 of pocket binder |
JP2000509689 |
1998-08-14 |
JP2001515063A |
2001-09-18 |
バクリンスキ,マイケル; ケー. ハッファー,オマー; パン,センリアン |
(57)【要約】 HIV統合前複合体(PIC)のマトリックスタンパク質成分のチロシン残基29ポケット中の隣接リジン残基上のアミノ成分を結合する、三次元空間での座標に従って限定された、化合物の1つの構造群が開示される。 本発明の化合物および医薬組成物は、PICがカリオフェリンαに結合するのを防止し、且つ宿主細胞DNA中へのHIVウイルスゲノムの核内侵入と組み込みを防止する。 よって、本発明の化合物および医薬組成物はHIVウイルス感染を防止する。 |
72 |
Sulfurized composition, and additive concentrates containing them and lubricating oil |
JP50092688 |
1988-12-22 |
JP2807299B2 |
1998-10-08 |
SHUROITSUKU KARUIN UIRIAMU |
Sulfurized mixtures which include (A) at least one partial fatty acid ester of a polyhydric alcohol, and (B) at least one member of the group consisting of (1) at least one fatty acid ester of a polyhydric alcohol, which fatty acid ester is different from the partial ester (A), (2) at least one fatty acid, (3) at least one olefin, and (4) at least one fatty acid ester of a monohydric alcohol. The sulfurized compositions are useful in preparing additive concentrates and lubricating compositions. |
73 |
Endothelin receptor antagonists |
JP50867293 |
1992-10-29 |
JP2667294B2 |
1997-10-27 |
エリオット,ジョン・ダンカン; カズンズ,ラッセル・ドノバン; ペイショフ,キャサリン・エリザベス; ラーゴ,マリア・アンパロ; レバー,ジャック・デール |
|
74 |
Hydrazines with insecticidal activity |
JP29062586 |
1986-12-08 |
JP2506093B2 |
1996-06-12 |
ROJAA UIRIAMUZU ADOO; DEBITSUDO JOOJI KUUN; DONARUDO PERII RAITO JUNIA |
|
75 |
It sulfurized lubricating oil composition |
JP50482385 |
1985-10-24 |
JPH08914B2 |
1996-01-10 |
ウオルシユ、リード、フーバー |
A sulfurized composition prepared by sulfurizing a mixture of at least one terpene and at least one other olefinic compound is described. More particularly, sulfurized compositions prepared by sulfurizing a mixture of pine oil and at least one other olefinic compound are described. Such sulfurized compositions are useful as lubricant additive compositions, and more particularly, as additive compositions in industrial and gear lubricants. The compositions when added to lubricants provide lubricants which exhibit improved antioxidant characteristics, nitrile seal compatibility and acceptable color characteristics. |
76 |
Insecticidal composition of hydrazine compound |
JP13101895 |
1995-05-01 |
JPH07330507A |
1995-12-19 |
ADDOR ROGER WILLIAMS; KUHN DAVID GEORGE; WRIGHT JR DONALD PERRY |
PURPOSE: To obtain a new diacylhydrazine compound effective as an insecticide for both crops being in growth and to be harvested. CONSTITUTION: This new compound is shown by formula I [R is a 2-6C alkyl; X, Y, M and N are H, a 1-3C alkyl, a 1-3C alkoxy, a 1-3C alkyl-S(O)n ((n) is 0-2), CN, a halogen, NO2 , CF3 , R1 CF2 Z, 1,1-difluoro-2,2-dichloroethoxy, R2 CO, R3 R4 N, or X and Y or M and N are joined together, to form OCH2 O, OCF2 O or a ring of formula II; Z is O or S(O)n ; R1 is H, F, CH2 F, CHFCl or CF3 ; R2 is a 1-3C alkyl, a 1-3C alkoxy or R3 R4 N; R3 is H or a 1-3C alkyl; R4 is the same as R3 or R5 CO (R5 is H or a 1-3C alkyl)], e.g. 1-benzoyl-1-t-butyl-2-(3,4- dichlorobenzoyl)hydrazine. The compound of formula I is obtained via a compound of formula IV (R6 is the same as R) as a new intermediate. |
77 |
Ink composition containing ultraviolet absorber |
JP26891094 |
1994-11-01 |
JPH07216275A |
1995-08-15 |
OI TATSU; MISAWA TSUTAYOSHI; ITO NAOTO; TAKUMA HIROSUKE |
PURPOSE: To obtain an ink composition containing a specific near infrared absorber, an ultraviolet absorber and a polyester resin, sensitive to near infrared rays, having excellent storage stability, giving a printed matter having excellent light resistance and useful for prepaid card, etc.
CONSTITUTION: This ink composition contains (A) a near infrared absorber selected from a dithiol compound of formula I [A
1 to A
8 each is H, a halogen, nitro, cyano, thiocyanato, etc.; R
1 to R
4 each is a (substituted) alkyl or a (substituted) aryl; M is a bivalent metal atom, a tri or tetravalent substituted metal atom or an oxo-metal], a dithiol compound of formula II (B
1 to B
4 each is H, cyano, an acyl, carbamoyl, etc.), a phthalocyanine compound of formula III [C
1 to C
16 each is H, a halogen, a (substituted) alkyl, a (substituted) lalkoxy, etc.] and a naphthalocyanine compound of formula IV (D
1 to D
24 each is same as C
1 to C
16), (B) an ultraviolet absorber absorbing the light of 250-400nm wavelength and (C) a polyester resin.
COPYRIGHT: (C)1995,JPO |
78 |
Liquid crystal compound, liquid crystal composition containing the compound, liquid crystal element using the composition, displaying method and displaying apparatus using the element |
JP34473893 |
1993-12-21 |
JPH07179371A |
1995-07-18 |
YAMADA YOKO; TAKIGUCHI TAKAO; IWAKI TAKASHI; TOKANOU GOUJI; NAKAMURA SHINICHI; NAKAZAWA IKUO |
PURPOSE: To obtain a new compound useful for a ferroelectric liquid crystal display device having excellent switching characteristics, quick response and small temperature dependency of optical response speed.
CONSTITUTION: This compound is expressed by the formula R-A-Y-X {R is a 1-20C alkyl, H or F; A is A
1, A
1-Z
1-A
2 or A
1-Z
1-A
2-Z
2-A
3 (A
1 to A
3 each is a substituted 1,4-phenylene, pyrimidine-2,5-diyl, etc.; Z
1 and Z
2 are each single bond, COO, OCO, CH
2O, CH=CH, C≡C, etc.); X is 2-bicyclo[2,2,1]heptyl, 1- tricyclo[3,3,1,1
3.7]decyl, etc.}, e.g. 2-(1-tricyclo[3,3,1,1
3.7]decylacetic acid 4-(5- decylpyrimidin-2-yl)phenyl ester. The compound of the formula is produced e.g. by reacting 4-(5-decylpyrimidin-2-yl)phenol with (1-tricyclo[3,3,1,1
3.7]decyl) acetic acid, 1,3-dicyclohexylcarbodiimide and 4-pyrrolidinopyridine.
COPYRIGHT: (C)1995,JPO |
79 |
JPH07501322A - |
JP50867293 |
1992-10-29 |
JPH07501322A |
1995-02-09 |
|
|
80 |
Mercapto - acylamino acid |
JP50615990 |
1990-04-06 |
JPH07593B2 |
1995-01-11 |
スミス,エリザベス・エム; デキャパイト,フィリップ・エム; ニュースタッド,バーナード・アール |
|