子分类：
| 序号 | 专利名 | 申请号 | 申请日 | 公开（公告）号 | 公开（公告）日 | 发明人 |
|---|---|---|---|---|---|---|
| 1 | 用作MoGAT-2抑制剂的新苄基磺酰胺化合物 | CN201380057789.8 | 2013-10-30 | CN104768941B | 2016-08-24 | F·J·阿赫哈斯-奇卡罗; N·迪亚兹比佐; J·M·格鲁贝尔; D·R·斯塔克 |
| 本发明提供式I化合物或其药学上可接受的盐：其中R1、L和A同文中所定义的，制备所述化合物的方法，以及利用所述化合物治疗病患例如高甘油三酯血症的方法。 | ||||||
| 2 | 用作MoGAT-2抑制剂的新苄基磺酰胺化合物 | CN201380057789.8 | 2013-10-30 | CN104768941A | 2015-07-08 | F·J·阿赫哈斯-奇卡罗; N·迪亚兹比佐; J·M·格鲁贝尔; D·R·斯塔克 |
| 本发明提供式I化合物或其药学上可接受的盐：其中R1、L和A同文中所定义的，制备所述化合物的方法，以及利用所述化合物治疗病患例如高甘油三酯血症的方法。 | ||||||
| 3 | 2,3-dihydro-1H-indole compounds | US15609115 | 2017-05-31 | US09872853B2 | 2018-01-23 | Jolie Anne Bastian; Jiehao Chen; Jeffrey Daniel Cohen; James Robert Henry; William Thomas McMillen; Bradley Earl Reaman; Almudena Rubio; Daniel Jon Sall; Gaiying Zhao |
| The present invention relates to certain novel 2,3-dihydro-1H-indole compounds, pharmaceutical compositions comprising the compounds, and methods of using the compounds to treat cancer, more particularly for the treatment of cancer selected from the group consisting of melanoma, acute myeloid leukemia, chronic lymphocytic leukemia, colorectal cancer, breast cancer, lung cancer, ovarian cancer, fallopian tube carcinoma, primary peritoneal carcinoma, cervical cancer, gastric cancer, liver cancer, pancreatic cancer, thyroid cancer, glioma, non-Hodgkin's lymphoma, and Hodgkin's lymphoma. | ||||||
| 4 | Process for the preparation of β-C-aryl glucosides | US13671461 | 2012-11-07 | US08952139B2 | 2015-02-10 | Julian Paul Henschke; Chen-Wei Lin; Ping-Yu Wu; Chi-Nung Hsiao; Jyh-Hsiung Liao; Tsung-Yu Hsiao |
| The present invention provides processes (e.g., arylation reaction) for stereoselectively preparing C-arylglucosides that can be useful as synthetic building block or drugs, including SGLT2 inhibitors. A representative process of the present application includes the preparation of the compound of formula IV starting from a compound of the formula II with a metalated aryl compound, as disclosed below: | ||||||
| 5 | Amine-based compound and organic light-emitting device including the same | US14963281 | 2015-12-09 | US09957441B2 | 2018-05-01 | Hyungseok Jang; Youngkook Kim; Jongwoo Kim; Jino Lim; Seokhwan Hwang |
| An amine-based compound and an organic light-emitting device, the amine-based compound being represented by Formula 1 below: | ||||||
| 6 | 2,3-DIHYDRO-1H-INDOLE COMPOUNDS | US15609115 | 2017-05-31 | US20170354641A1 | 2017-12-14 | Jolie Anne Bastian; Jiehao Chen; Jeffrey Daniel Cohen; James Robert Henry; William Thomas McMillen; Bradley Earl Reaman; Almudena Rubio; Daniel Jon Sall; Gaiying Zhao |
| The present invention relates to certain novel 2,3-dihydro-1H-indole compounds, pharmaceutical compositions comprising the compounds, and methods of using the compounds to treat cancer, more particularly for the treatment of cancer selected from the group consisting of melanoma, acute myeloid leukemia, chronic lymphocytic leukemia, colorectal cancer, breast cancer, lung cancer, ovarian cancer, fallopian tube carcinoma, primary peritoneal carcinoma, cervical cancer, gastric cancer, liver cancer, pancreatic cancer, thyroid cancer, glioma, non-Hodgkin's lymphoma, and Hodgkin's lymphoma. | ||||||
| 7 | Process for the Preparation of ß-C-Aryl Glucosides | US13671461 | 2012-11-07 | US20140128595A1 | 2014-05-08 | Julian Paul Henschke; Chen-Wei Lin; Ping-Yu Wu; Chi-Nung Hsiao; Jyh-Hsiung Liao; Tsung-Yu Hsiao |
| The present invention provides processes for stereoselectively preparing C-arylglucosides that can be useful as synthetic building block or drugs, including SGLT2 inhibitors. | ||||||
| 8 | Benzyl sulfonamide compounds useful as MoGAT-2 inhibitors | US14438435 | 2013-10-30 | US09416138B2 | 2016-08-16 | Francisco Javier Agejas-Chicharro; Nuria Diaz Buezo; Joseph Michael Gruber; Douglas Richard Stack |
| The present invention provides compounds of Formula I. Wherein R1, L, and A are as described herein, or a pharmaceutical salt thereof, processes for preparing the compounds, and methods of treating a condition, such as hypertriglyceridemia, using the compounds. | ||||||
| 9 | AMINE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | US14963281 | 2015-12-09 | US20160190467A1 | 2016-06-30 | Hyungseok JANG; Youngkook KIM; Jongwoo KIM; Jino LIM; Seokhwan HWANG |
| An amine-based compound and an organic light-emitting device, the amine-based compound being represented by Formula 1 below: | ||||||
| 10 | NOVEL BENZYL SULFONAMIDE COMPOUNDS USEFUL AS MOGAT-2 INHIBITORS | US14438435 | 2013-10-30 | US20150284404A1 | 2015-10-08 | Francisco Javier Agejas-Chicharro; Nuria Diaz Buezo; Joseph Michael Gruber; Douglas Richard Stack |
| The present invention provides compounds of Formula I. Wherein R1, L, and A are as described herein, or a pharmaceutical salt thereof, processes for preparing the compounds, and methods of treating a condition, such as hypertriglyceridemia, using the compounds. | ||||||
| 11 | ＭｏＧＡＴ−２阻害剤として有用な新規のベンジルスルホンアミド化合物 | JP2015540743 | 2013-10-30 | JP2016501844A | 2016-01-21 | フランシスコ・ハビエル・アヘハス−チチャロ; ヌリア・ディアス・ブエソ; ジョゼフ・マイケル・グルーバー; ダグラス・リチャード・スタック |
| 本発明は、式Iの化合物(式中、R1、LおよびAは、本明細書に述べる通りである)またはその薬学的な塩、化合物を調製するためのプロセス、および化合物を用いて高トリグリセリド血症などの病態を治療する方法を提供する。 | ||||||
| 12 | NOVEL BENZYL SULFONAMIDE COMPOUNDS USEFUL AS MOGAT-2 INHIBITORS | EP13789443.2 | 2013-10-30 | EP2917194B1 | 2017-09-27 | AGEJAS-CHICHARRO, Francisco Javier; DIAZ BUEZO, Nuria; GRUBER, Joseph Michael; STACK, Douglas Richard |
| 13 | NOVEL BENZYL SULFONAMIDE COMPOUNDS USEFUL AS MOGAT-2 INHIBITORS | EP13789443.2 | 2013-10-30 | EP2917194A1 | 2015-09-16 | AGEJAS-CHICHARRO, Francisco Javier; DIAZ BUEZO, Nuria; GRUBER, Joseph Michael; STACK, Douglas Richard |
| The present invention provides compounds of Formula I. Wherein Rl, L, and A are as described herein, or a pharmaceutical salt thereof, processes for preparing the compounds, and methods of treating a condition, such as hypertriglyceridemia, using the compounds. | ||||||
| 14 | 시알로키메릭 화합물 | KR1020127013207 | 2010-11-25 | KR1020120101397A | 2012-09-13 | 베로네시,파울로알베르토; 로드리게스.파블로이.에이.; 베로네시,안나마리아; 페쉐체라,엠마누엘라 |
| 본 발명은 다른 약물들에 내성이거나 내성이 아닐 수도 있는 A형 및 B형 인플루엔자 바이러스뿐만 아니라 다른 유형의 바이러스들, 예를 들어 플라비바이러스 및 또한 원생동물 및 다른 미생물들에 대해 억제 효과를 발휘하는 신규 부류의 화합물, 그의 제조 방법, 상기 화합물을 함유하는 약학 제형, 및 동물 및 인간 건강에 영향을 미치는 바이러스, 세균 및 원생동물을 포함한 특정 미생물에 의해 유발되는 다양한 병의 치료를 위한 약품으로서 그의 용도를 개시한다.
|
||||||
| 15 | 아민계 화합물 및 이를 포함한 유기 발광 소자 | KR1020140194320 | 2014-12-30 | KR1020160081099A | 2016-07-08 | 장형석; 김영국; 김종우; 임진오; 황석환 |
| 아민계화합물및 이를포함한유기발광소자가개시된다. | ||||||
| 16 | MOGAT-2 억제제로서 유용한 신규 벤질 술폰아미드 화합물 | KR1020157011222 | 2013-10-30 | KR1020150063519A | 2015-06-09 | 아제하스-치차로,프란시스코하비에르; 디아즈부에조,누리아; 그루버,조셉마이클; 스택,더글라스리차드 |
| 본발명은하기화학식 I의화합물또는그의제약염, 상기화합물을제조하는방법, 및상기화합물을사용하여고트리글리세리드혈증과같은상태를치료하는방법을제공한다. <화학식 I>상기식에서, R1, L 및 A는본원에정의된바와같다. | ||||||
QQ群二维码
意见反馈
意见反馈