首页 / 国际专利分类库 / 化学;冶金 / C07有机化学 / 有机化学的一般方法;所用的装置 / 纯化;分离(旋光化合物的分离入C07B57/00);稳定化;添加剂的使用
序号 专利名 申请号 申请日 公开(公告)号 公开(公告)日 发明人
181 ORGANO-CATALYTIC BIOMASS DECONSTRUCTION US15682125 2017-08-21 US20170369955A1 2017-12-28 Ming Qiao; Randy D. Cortright; Elizabeth Woods
The present invention provides processes for catalytic deconstruction of biomass using a solvent produced in a bioreforming reaction.
182 METHOD OF REMOVING CALCIUM FROM HYDROCARBON FRACTION USING EXTRACTION AGENT INCLUDING 2-OXOPROPANOL OR DERIVATIVES THEREOF US15606181 2017-05-26 US20170342329A1 2017-11-30 Dong-Woo CHO; Jong-Nam KIM; Su Jin JEONG; Hee Tae BEUM; Taesung JUNG; Hyung Chul YOON; Kanghee CHO; Sang-Sup HAN
Disclosed is a method of removing calcium from a hydrocarbon fraction using an extraction agent including 2-oxopropanal or derivatives thereof, the method including (S1) adding a hydrocarbon fraction with an extraction agent including 2-oxopropanal or derivatives thereof to give a mixture, (S2) converting an oil-soluble calcium compound into a water-soluble calcium compound by reacting the hydrocarbon fraction with the 2-oxopropanal or derivatives thereof, and (S3) removing the water-soluble calcium compound.
183 Organo-catalytic biomass deconstruction US15364764 2016-11-30 US09738944B2 2017-08-22 Ming Qiao; Randy D. Cortright; Elizabeth Woods
The present invention provides processes for catalytic deconstruction of biomass using a solvent produced in a bioreforming reaction.
184 Bisphenol A preparation apparatus and preparation method US14904028 2014-07-11 US09573869B2 2017-02-21 Jong Suh Park; Joon Ho Shin; Tae Woo Kim; Jong Ku Lee; Se Ho Park
Provided are an apparatus and a method for preparing bisphenol A. In the present invention, all or some of a mother liquid stream is circulated to a flash rector through a bypass line after crystallization in a process of preparing bisphenol A so as to increase a conversion rate of bisphenol A in a reactor, reduce energy, and use a heating source of phenol to be discharged to an upper side of the flash reactor, and thus the reaction efficiency of the whole process can be increased.
185 APPARATUS AND METHOD FOR PURIFYING CUMENE US15304017 2015-05-22 US20170044081A1 2017-02-16 Sung Kyun KIM; Sung Kyu LEE; Joon Ho SHIN
The present application relates to an apparatus and method for purifying cumene. The apparatus and method for purifying cumene according to the present application can reduce the amount of energy consumption which occurs during purification processes and can provide an apparatus and method capable of efficiently purifying cumene.
186 Methods for producing bioderived propylene glycol US14613877 2015-02-04 US09533930B2 2017-01-03 Kevin J. Adlaf; Paul D. Bloom; William Chris Hoffman; Chicheng Ma; John G. Soper; Brad Zenthoefer
In the process of distilling a polyol product mixture including one or both of a biobased propylene glycol and a biobased ethylene glycol from the reaction of hydrogen with a biobased feed, it has been discovered that undesirable epoxides can form, and the present invention provides means for guarding against their formation, for removing epoxides which do form by particular methods of distilling, and for removing the epoxides from a finished, otherwise commercially acceptable biobased glycol product.
187 Method of separating acids from chemical reaction mixtures by means of apolar amines US15148430 2016-05-06 US09493491B2 2016-11-15 Oliver Huttenloch; Patrick Deck; Holger Ganz; Michael Mauss; Wolfgang Körnig; Michael Bock
A process for the removal of acids from reaction mixtures, comprising at least one product of value which is sparingly soluble in water, by at least one unpolar amine as an auxiliary base, which includes: a) reacting the auxiliary base with the acid with formation of a salt; b) reacting the salt formed in step a) with a further base which accepts the acid with liberation of the auxiliary base and combines with the acid to be accepted from the auxiliary base to form a salt which is very readily soluble in water; c) extraction of the mixture obtained in step b) with water or an aqueous medium, wherein the salt of the further base dissolves in the aqueous phase and the product of value, or the solution of the product of value, in a suitable solvent and the auxiliary base form at least one separate nonaqueous phase; and d) removal by distillation of at least part of any solvent present from the at least one nonaqueous phase obtained in step c), to form two nonmiscible liquid phases.
188 METHOD FOR RECOVERING CATALYST US15038190 2014-12-09 US20160288115A1 2016-10-06 Markus NUOPPONEN; Lauri KUUTTI; Stella ROVIO
A catalyst is recovered from an aqueous reaction mixture comprising heterocyclic nitroxyl catalyst and oxidized cellulose, by: —separating the oxidized cellulose from the reaction mixture, —contacting the reaction mixture with solid hydrophobic adsorbent particles with particle sizes below 350, preferably below 200 μm, more preferably below 100 μm, said particles being silica particles provided with functionnalized hydrophobicity, —adsorbing the catalyst to the hydrophobic adsorbent particles, and—eluting the catalyst from the adsorbent particles with an organic solvent.
189 Sorbent comprising on its surface a cationic or protonizable aliphatic residue for the purification of organic molecules US14344718 2012-09-17 US09452415B2 2016-09-27 Markus Arendt; Björn Degel; Thomas Schwarz; Gerhard Stumm; Martin Welter
The present invention relates to a sorbent comprising a solid support material, the surface of which comprises a residue of a general formula (I), wherein the residue is attached via a covalent single bond to a functional group on the surface of either the bulk solid support material itself or of a polymer film on the surface of the solid support material. Furthermore, the present invention relates to the use of the sorbent according to the invention for the purification of organic molecules, in particular pharmaceutically active compounds, preferably in chromatographic application.
190 METHOD OF SEPARATING ACIDS FROM CHEMICAL REACTION MIXTURES BY MEANS OF APOLAR AMINES US15148430 2016-05-06 US20160251384A1 2016-09-01 OLIVER HUTTENLOCH; Patrick DECK; Holger GANZ; Michael MAUSS; Wolfgang KÖRNIG; Martin BOCK
A process for the removal of acids from reaction mixtures, comprising at least one product of value which is sparingly soluble in water, by at least one unpolar amine as an auxiliary base, which includes: a) reacting the auxiliary base with the acid with formation of a salt; b) reacting the salt formed in step a) with a further base which accepts the acid with liberation of the auxiliary base and combines with the acid to be accepted from the auxiliary base to form a salt which is very readily soluble in water; c) extraction of the mixture obtained in step b) with water or an aqueous medium, wherein the salt of the further base dissolves in the aqueous phase and the product of value, or the solution of the product of value, in a suitable solvent and the auxiliary base form at least one separate nonaqueous phase; and d) removal by distillation of at least part of any solvent present from the at least one nonaqueous phase obtained in step c), to form two nonmiscible liquid phases.
191 Method and device for producing and/or purifying polynucleotides and products obtainable thereof US14451951 2014-08-05 US09416400B2 2016-08-16 Philippe Ledent
An apparatus and a method for obtaining a (poly)nucleotide sequence of interest include steps of cultivating hosts cells to produce a nucleotide sequence of interest and harvesting these cells, introducing these cells in a passageway and disintegrating them in a continuous process. In the continuous process, performing in the passageway a precipitation of contaminants by a mixing of the disintegrated cells with a solution containing one or more salt(s) and obtaining a mixture and allowing a precipitate to separate from the solution of this mixture, preferably to float and/or to sediment from the solution of this mixture for 1-48 hours and pumping out a soluble material from this solution, while excluding recovering the precipitate.
192 Method for purification of nucleic acids, particularly from fixed tissue US14199019 2014-03-06 US09416399B2 2016-08-16 Heike Euting; Guido Hennig; Alexandre Izmailov
The invention relates to a method for purification of nucleic acids, to a kit for performing the method according to the invention and to a new application of magnetic particles for purification of a biological sample. The method according to the invention comprises the following steps: a) accommodating of the sample in a first sample vessel in an aqueous solution and lysing of the sample under non-chaotropic conditions; suspending of first magnetic particles in the solution and inserting of the first sample vessel in a sample vessel holder, wherein the sample vessel is inserted in the annular interior space of a ring magnet associated with the sample vessel holder; separating of the solution from the magnetic particles; and isolating of the nucleic acids from the solution.
193 Method for producing complex crystal and method for screening complex crystal US14113239 2012-04-20 US09382250B2 2016-07-05 Akinori Goto; Mamoru Fukuda
The present invention relates to a method for producing a complex crystal composed of two or more different compounds, comprising crystallizing the two or more different compounds under a condition at which menthol is heat melted, and a method for screening a complex crystal. In accordance with the method for producing a complex crystal of the present invention, a complex crystal capable of being used as a drug material can be produced rapidly, simply and efficiently. In addition, in accordance with the method for screening a complex crystal of the present invention, a stable complex crystal can be searched, which is industrially useful.
194 BISPHENOL A PREPARATION APPARATUS AND PREPARATION METHOD US14904028 2014-07-11 US20160159716A1 2016-06-09 Jong Suh PARK; Joon ho SHIN; Tae Woo KIM; Jong Ku LEE; Se Ho PARK
Provided are an apparatus and a method for preparing bisphenol A. In the present invention, all or some of a mother liquid stream is circulated to a flash rector through a bypass line after crystallization in a process of preparing bisphenol A so as to increase a conversion rate of bisphenol A in a reactor, reduce energy, and use a heating source of phenol to be discharged to an upper side of the flash reactor, and thus the reaction efficiency of the whole process can be increased.
195 Method of separating acids from chemical reaction mixtures by means of apolar amines US12092392 2006-09-15 US09359269B2 2016-06-07 Oliver Huttenloch; Patrick Deck; Holger Ganz; Michael Mauβ; Wolfgang Körnig; Michael Bock
A process for the removal of acids from reaction mixtures, comprising at least one product of value which is sparingly soluble in water, by at least one unpolar amine as an auxiliary base, which includes: a) reacting the auxiliary base with the acid with formation of a salt; b) reacting the salt formed in step a) with a further base which accepts the acid with liberation of the auxiliary base and combines with the acid to be accepted from the auxiliary base to form a salt which is very readily soluble in water; c) extraction of the mixture obtained in step b) with water or an aqueous medium, wherein the salt of the further base dissolves in the aqueous phase and the product of value, or the solution of the product of value, in a suitable solvent and the auxiliary base form at least one separate nonaqueous phase; and d) removal by distillation of at least part of any solvent present from the at least one nonaqueous phase obtained in step c), to form two nonmiscible liquid phases.
196 Purification method US14619871 2015-02-11 US09346771B2 2016-05-24 Eric Horn; Steven Fairway; Dimitrios Mantzilas; Nigel Powell
A diagnostic imaging agent useful for positron emission tomography (PET) imaging as well as to improved hardware for producing such imaging agents is described. Flutemetamol (18F) Injection for the imaging of β-amyloid plaques in the brain and methods and devices for preparing same are described including the automated synthesis and purification of [18F]flutemetamol by means of solid phase extraction (SPE).
197 Chromatographic material and method for preparation thereof US14526996 2014-10-29 US09340562B1 2016-05-17 Xiaodong Liu; Richard T. Williams; Xiao Cui
A chromatographic material comprising a zwitterionic ligand covalently bound to a substrate, the ligand preferably has a formula II: wherein R1, R2, R3 are independently selected from an oxygen atom that is configured to connect to a substrate atom in the substrate, an oxygen atom that is configured to connect to a silicon atom of an adjacent ligand, a hydroxyl group, a halogen atom, an alkoxy group, a dialkylamino group, an acyl group, an alkyl group, or an aryl group; L1, L2 and L3 are independently hydrophobic moieties; each containing 2 to 30 carbon atoms, wherein there are at least 10 carbon atoms in the combined chain lengths of L1, L2 and L3; X is an O atom, S atom, amide group or sulfonamide group; n is 0 or 1; R4, R5 are independently selected from a hydrogen atom or a hydrocarbon moiety containing 1 to 20 carbon atoms; and Rf is a negatively charged moiety comprising a sulfonic, carboxylic, or phosphonic functional group.
198 CHROMATOGRAPHIC MATERIAL AND METHOD FOR PREPARATION THEREOF US14526996 2014-10-29 US20160122368A1 2016-05-05 Xiaodong LIU; Richard T. WILLIAMS; Xiao CUI
A chromatographic material comprising a zwitterionic ligand covalently bound to a substrate, the ligand preferably has a formula II: wherein R1, R2, R3 are independently selected from an oxygen atom that is configured to connect to a substrate atom in the substrate, an oxygen atom that is configured to connect to a silicon atom of an adjacent ligand, a hydroxyl group, a halogen atom, an alkoxy group, a dialkylamino group, an acyl group, an alkyl group, or an aryl group; L1, L2 and L3 are independently hydrophobic moieties; each containing 2 to 30 carbon atoms, wherein there are at least 10 carbon atoms in the combined chain lengths of L1, L2 and L3; X is an O atom, S atom, amide group or sulfonamide group; n is 0 or 1; R4, R5 are independently selected from a hydrogen atom or a hydrocarbon moiety containing 1 to 20 carbon atoms; and Rf is a negatively charged moiety comprising a sulfonic, carboxylic, or phosphonic functional group.
199 ORGANO-CATALYTIC BIOMASS DECONSTRUCTION US14968361 2015-12-14 US20160097108A1 2016-04-07 Ming Qiao; Randy D. Cortright; Elizabeth Woods
The present invention provides processes for catalytic deconstruction of biomass using a solvent produced in a bioreforming reaction.
200 Methods and apparatus for the ion mobility based separation and collection of molecules US13651837 2012-10-15 US09257269B2 2016-02-09 Ching Wu
This invention describes an apparatus and method with a combined primary electrospray and secondary electrospray ionization source used to enhance ionization efficiency. The solid phase as well as liquid phase sampling, ionization, and detection is described.
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