| 序号 | 专利名 | 申请号 | 申请日 | 公开（公告）号 | 公开（公告）日 | 发明人 |
|---|---|---|---|---|---|---|
| 101 | PAN COATING APPARATUS | US13124716 | 2009-10-09 | US20110197810A1 | 2011-08-18 | Yasutoyo Fusejima; Takuya Nakamura; Takashi Terada; Shigemi Isobe |
| A spray gun (31) is attached to a multi-function unit (32) movable in a horizontal direction and a perpendicular direction. The spray gun (31) is mounted to a support holder (33), and the support holder (33) is connected to a support arm (35) of the multi-function unit (32). The support arm (35) is attached to a unit cover (36) which is openable/closable with respect to a casing (2). The support holder (33) and the support arm (35) can hide and house a liquid hose and an air hose therein so that the hoses and the like are arranged in an apparatus in such a state as to be completely free from being exposed. An installation position of the spray gun (31) can be finely adjusted by the multi-function unit (32) during a coating process, thereby enabling a control for keeping constant distances between tablet surfaces and the spray gun (31). | ||||||
| 102 | DRUM COATER HAVING A NIR MEASURING UNIT | US12996184 | 2009-06-10 | US20110088620A1 | 2011-04-21 | Frank Maurer |
| The film coating device having a perforated drum is provided with a stationary NIR measuring unit on the outside of the rotating drum wall. The measurement is made through the drum wall. | ||||||
| 103 | PRODUCTION COATER WITH EXCHANGEABLE DRUMS | US12493710 | 2009-06-29 | US20100206223A1 | 2010-08-19 | Timothy C. Pilipauskas; Shawn Garcia; Jean Y. Le Floch |
| A coater for coating a material with a solution or a suspension includes an access door and a process port separately openable within a housing. A rotating coating drum is removably connected with respect to the coater and the coater is configured for exchange of drums having a wide range of production capacities. | ||||||
| 104 | Powder Processing Apparatus | US12718614 | 2010-03-05 | US20100155516A1 | 2010-06-24 | Makio Naito; Hiroya Abe; Kiyoshi Nogi; Masuo Hosokawa; Takehisa Fukui; Masahiro Yoshikawa |
| In order to manufacture the compound powder or the porous granulated substance in an efficient manner, a powder processing apparatus has an accumulating face on which the processing target powder is to be accumulated and a processing face disposed in opposition to the accumulating face and convexly curved, and a moving means for moving the accumulating face and the processing face along the accumulating face relative to each other. The apparatus comprises an excitement treatment means capable of applying an excitation energy to the processing target powder accumulated on the accumulating face from an excitation energy supplying portion disposed in opposition to the accumulating face or an oscillation means for oscillating the accumulating face or the processing face in a direction intersecting the accumulating face. | ||||||
| 105 | Powder processing method | US10561600 | 2003-11-13 | US07686238B2 | 2010-03-30 | Makio Naito; Hiroya Abe; Kiyoshi Nogi; Masuo Hosokawa; Takehisa Fukui; Masahiro Yoshikawa |
| In order to manufacture the compound powder or the porous granulated substance in an efficient manner, a powder processing apparatus has an accumulating face on which the processing target powder is to be accumulated and a processing face disposed in opposition to the accumulating face and convexly curved, and a moving means for moving the accumulating face and the processing face along the accumulating face relative to each other. The apparatus comprises an excitement treatment means capable of applying an excitation energy to the processing target powder accumulated on the accumulating face from an excitation energy supplying portion disposed in opposition to the accumulating face or an oscillation means for oscillating the accumulating face or the processing face in a direction intersecting the accumulating face. | ||||||
| 106 | Rotary Pan | US11910366 | 2006-04-07 | US20080264333A1 | 2008-10-30 | Nicola Gandolfi; Roberto Trebbi |
| Described is a rotary pan (1) of the type comprising a central hollow cylindrical body (3) with end portions (4, 4′) shaped substantially like truncated cones, and mixing/deflecting means (7) attached to at least one inside surface of the pan (1) itself; the peripheral inside cylindrical surface (5) of the hollow body (3) comprises an extended zone (A) defined by a uniform distribution of through holes (6) and at least one zone (B) within the zone (A) forming an area by which the mixing/deflecting means (7) are attached or fixed to the peripheral surface (5). | ||||||
| 107 | Continuous combined pigmented wax compounding and bichromal sphere fabrication process | US10397017 | 2003-03-25 | US07374797B2 | 2008-05-20 | Y. Martin Lu |
| A system and method for the continuous fabrication of bichromal spheres by introducing continuous streams of differently colored, pigmented polymer melts to substantially opposite sides of a plurality of spinning disks. The system comprises a first and second extruder which melts a raw polymer material and mixes the melted polymer with a pigment and optionally a charge control agent. The first and second extruders are connected to substantially opposite sides of a plurality of spinning disks with optionally interconnected gear pumps and mixing devices. The instant system and method is useful in fabricating large quantities of bichromal spheres in a continuous manner with a higher degree of uniformity in their physical characteristics. | ||||||
| 108 | Methods of combining active agents with augmented microcrystalline cellulose | US11103038 | 2005-04-11 | US20060228487A1 | 2006-10-12 | David Schaible; Bob Sherwood |
| A process for preparing agglomerated particles comprising a) providing an active agent in a form suitable for spray drying; and b) combining the active agent with dry silicified microcrystalline cellulose in coating pan or fluid-bed dryer to form agglomerated particles. | ||||||
| 109 | Apparatus for treating a particulate material and method for operating the apparatus | US11201080 | 2005-08-10 | US20060032435A1 | 2006-02-16 | Herbert Huettlin; Wolfgang Huettlin; Kai Koch; Christian Toschka |
| An apparatus for treating a particulate material comprising a container, which has a base, an upright wall, extending from bottom to top, and, in an upper region, a deflecting element, to deflect the material rising up along the wall in its direction of movement in such a way that it can return again to the base, it being possible for at least the wall to be driven in rotation about a vertical axis of rotation. In the upper region of the container there is at least one container element which can be driven in rotation in the same direction as the upright wall, but with lower rotational speed, about the vertical axis of rotation. | ||||||
| 110 | Preparation method of drug-containing spherical fine particles | US09830345 | 2001-04-26 | US06692768B1 | 2004-02-17 | Takashi Ishibashi; Keigo Nagao; Kengo Ikegami; Hiroyuki Yoshino; Masakazu Mizobe |
| The present invention discloses an efficient preparation method of spherical fine particles containing a drug for an easily-swallowed, controlled-release preparation comprising the production of drug-containing spherical fine particles (mean particle size: 60-200 &mgr;m) by adding a binder solution to a mixture containing an excipient powder having the property of retaining solvent (and preferably having a mean length of the long axis of 40 &mgr;m or less) and a drug powder (preferably having a mean length of the long axis of 50 &mgr;m or less), followed by high-speed mixing granulation. | ||||||
| 111 | Method for the formation of solid particles from a liquid | US09806032 | 2001-05-18 | US06676860B1 | 2004-01-13 | Alf Andersson |
| Solid particles are formed from a liquid by rotating a slinger about a vertical axis within a chamber to sling liquid droplets from vertically spaced annular rows of cusps disposed on an outer periphery of the slinger. An air flow is established within the chamber, the air flow rotating in a direction opposite the direction of rotation of the slinger. The air flow opposes travel of threads formed between successively slung droplets to cause the threads to separate from the droplets and turn into dust particles which become entrained in the air flow. The dust particles can thus be collected separately from particles formed by the droplets. | ||||||
| 112 | Wet granulation method for generating granules | US10252973 | 2002-09-24 | US20030135957A1 | 2003-07-24 | Robin Phinney |
| A method of wet granulation of fertilizer and other materials into granules. The method involves formation of the granule directly on the pan from the feedstock without intermediate steps or the use of seed materials. The result is a product having a completely uniform cross section. The feedstock is initially in the size distribution of null150 mesh with 90% or greater in the size range of 200 mesh. Moisture is maintained to facilitate a steady process without cycling. The method has the advantage of allowing granulation of materials either known to be hazardous or inherently difficult to granulate in a safe and expedient manner. The process permits the formation of multiple feedstock granules. The initial feedstock may be augmented with a different feedstock in a second pan having a different composition and size from the initial feedstock. | ||||||
| 113 | Method of manufacturing spherical bodies by rotation, spherical bodies made by the method and a powder composition for use in the method | US09417208 | 1999-10-13 | US06464906B1 | 2002-10-15 | Tomonori Niwa; Tetsuji Yogo |
| A method of making spherical bodies from powder, which comprises (1) preparing an adjusted powder so as to have at least one powder characteristic selected from the group consisting of an average particle size, a powder particle size distribution and a BET specific surface area, (2) preparing nuclei having a particle size larger than that of the adjusted powder, (3) rotating the nuclei, and (4) adding the adjusted powder and a solvent to the rotating nuclei so that particles of the adjusted powder accumulate on the nuclei to form granular bodies. Also disclosed is a spherical body having a core or nucleus formed in the spherical body, an adjusted powder composition for forming a spherical body, and a method for manufacturing spherical sintered bodies of silicon nitride. | ||||||
| 114 | Apparatus and method for the formation of droplets from a liquid | US09816172 | 2001-03-26 | US20010028002A1 | 2001-10-11 | Alf Andersson |
| Droplets are formed from a liquid by supplying liquid to a feeding rotor and rotating the feeding rotor about an axis to discharge the liquid generally radially outwardly by centrifugal force. A distributor disposed radially outside of the feeding rotor is rotated relative to the feeding rotor about the axis to receive liquid discharged from the feeding rotor. A slinger disposed radially outside of the distributor is rotated relative to the distributor about the axis to receive liquid discharged from the distributor by centrifugal force. The slinger slings that received liquid is slung outwardly in the form of droplets from cusps distributed circumferentially around an outer periphery of the slinger. | ||||||
| 115 | Apparatus and a method for treating particulate materials | US09077931 | 1998-11-13 | US06270801B1 | 2001-08-07 | Kim Walter |
| In an apparatus for producing and/or processing granules, pellets or other particulate materials, having a rotary disc tight within a chamber and means for providing an upward gas stream through a slot between said disc and the chamber wall as well as means for spraying a liquid or steam onto the particulate material and possibly means for introducing powder for use in a powder layering process, the flow patter of the particulate material, which is maintained in non-fluidized condition, is improved by gas injection towards the center of the chamber or disc. A more uniform product having desired properties is obtained and the capacity is improved. The gas injection enables upscaling of apparatus and method. | ||||||
| 116 | Comminution and distribution device for comminutable, pumpable materials | US09276748 | 1999-03-26 | US06186426B1 | 2001-02-13 | Anton Killer |
| The comminution and distribution device according to the invention can be used to crush comminutable, pumpable materials, in particular mechanically dewatered slurry, into roughly the same sized pieces, and feed them in controllable quantities to a downstream device, e.g., a dryer. To this end, the slurry is conveyed through a gap formed by two oppositely rotatable parts. In preferred embodiments of the device according to the invention, both parts exhibit recesses on the side facing the gap, which are designed in such a way that, when the two parts are turned opposite each other in the preset rotational direction, slurry strands with periodically alternating areas with smaller and larger cross sections are formed, transported outside and split at locations exhibiting smaller cross sections. | ||||||
| 117 | Spherical granule, process for producing the same, and spherical granule preparations using the same | US09254438 | 1999-03-09 | US06171619B2 | 2001-01-09 | Yasutoyo Fusejima; Yasuhiro Takemura; Nagayoshi Myo; Hisayoshi Kato |
| The invention relates to spherical granules having a uniform grain size and a uniform density which are suitable for a controlled-release preparation, a process for producing the same, and a spherical granule preparation using the same. Specifically, the invention relates to a process for producing spherical granules comprising the steps of: wetting powder materials comprising one or more kinds of pharmaceutical substances and have a mean particle size of from 1 to 100 &mgr;m; charging the wet powder materials into a centrifugal fluidized granulating apparatus; spraying a liquid to the wet powder materials at a rate of less than 3% based on the plastic limit of the powder materials per min. while rotating the rotary disk of the centrifugal fluidized granulating apparatus until the liquid content of the powder materials reaches 75 to 120% based on the plastic limit of the powder materials, and drying the sprayed product to give spherical granules; spherical granules having a mean grain size of 100-1000 &mgr;m, in which at least 90% by weight of the total amount of the spherical granules has such a grain size distribution that the maximum grain size is not larger than 1.2 times the minimum grain size, and the difference in density between the individual spherical granules is less than 0.05 g/cm3; and a spherical granule preparation comprising the spherical granules. | ||||||
| 118 | Spin disk encapsulation apparatus and method of use | US886266 | 1997-07-01 | US6001387A | 1999-12-14 | Kent C. Cochrum |
| An encapsulating apparatus comprising a spinning cup adjustably rotatable about its central axis for forming droplets and projecting them radially outward, and one or more collection basins surrounding the bead forming spinning cup independently rotatable and positioned to collect the beads projected from the cup. The method for forming tissue microcapsules using the spin disk encapsulation apparatus wherein a supply mixture is introduced into a mixing chamber of the cup from a single, multiple or concentric needles. As the cup spins, the coated particles are propelled upward by the centrifugal force from the mixing chamber along the inner surface of the cup, projected radially outward, as beads, into the gelling solution in one of the selected basins. | ||||||
| 119 | Granulated powder of polytetrafluoroethylene for molding and process for the production thereof | US68123 | 1998-05-07 | US5994499A | 1999-11-30 | Michio Asano; Shingo Tanigawa; Tetsuo Shimizu; Shoji Kawachi |
| To provide a polytetrafluoroethylene granular powder for molding and a process for preparing the granular powder, in which the granular powder contains only a small number of coarse particles, is obtained with good tumbling efficiency and further no organic liquid is required to be used. The process is for preparing a polytetrafluoroethylene granular powder for molding by granulating a polytetrafluoroethylene powder through tumbling with a granulator having a rotating inclined disc and a rotating side plate; characterized in that the granulator:(1) comprises a disc inclined to a horizontal level and a side plate provided on the periphery of the disc,(2) has the side plate assembled in one unit with the disc and rotating together, and(3) is equipped with an agitator positioned eccentrically to the center of a vortex of the polytetrafluoroethylene powder which is caused by tumbling,or the granulator:(1) comprises a disc inclined to a horizontal level and a side plate provided on the periphery of the disc,(2) has the side plate separated from the disc and being rotatable around the periphery of the disc, and(3) is equipped with an agitator positioned eccentrically to the center of a vortex of the polytetrafluoroethylene powder which is caused by tumbling,and that the granulation is carried out by tumbling the polytetrafluoroethylene powder wetted with an aqueous solution containing a surfactant. | ||||||
| 120 | Apparatus for cooling and processing a molten product into a granulate product | US727410 | 1997-01-21 | US5772187A | 1998-06-30 | Abimanjoe Saroso Wirodihardjo; Wijnand Jacob t Hart; Alwin Graafland |
| An apparatus for cooling and processing a molten product into a granulate product which apparatus comprises a displaceable support consisting of at least one substantially horizontal, disk-shaped element arranged for rotation about a substantially vertical shaft, means for depositing the molten product on the support, cooling means containing cooling liquid channels closed in themselves that form part of the disc-shaped element and, without connection with the environment, connect to feed and discharge means, and means for removing the molten product from the support in granulate form. Preferably, a double spiral-shaped channel is present per disk-shaped element, and the means for depositing the molten product on the support comprise a dispenser adapted to dispense the molten product batchwise or dropwise. | ||||||
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