TREATMENT OF INFLAMMATORY DISEASES OF THE GASTRO-INTESTINAL TRACT
专利汇可以提供TREATMENT OF INFLAMMATORY DISEASES OF THE GASTRO-INTESTINAL TRACT专利检索，专利查询，专利分析的服务。并且The present invention provides use of a peptide or ligand in the manufacture of a medicament for the treatment of certain inflammatory diseases of the gastro-intestinal tract, such as coeliac disease, Crohn's disease, ulcerative colitis etc., and a method of treatment of the diseases comprising administering an effective dose of a medicament comprising the peptide or ligand. The peptide has not more than 20 amino acid residues, and comprises a thiol-active cysteine residue and at least two positively charged amino acid residues situated at, adjacent or near to the N terminus or at, adjacent or near to the C terminus or at, adjacent or near to both termini; or this peptide and a pharmaceutically acceptable diluent or carrier. Preferably the peptide or analog comprises amino acid residues having a sequence selected from the group which comprises: Cys-Lys-Lys, His-Cys-Lys-Lys (SEQ ID NO:1). Also, the invention can provide a method of treatment of IDGIT comprising administering an effective dose of a peptide or analogue thereof having general formula (I) wherein m is 0 or 1, n is 0 or 1 and m + n is 1 or 2; J and J represent sequences of positively charged amino acid residues; Z , Z , B and B represent sequences of residues of positively charged, negatively charged or neutral amino acid residues or sequences of any mixture of positively charged, negatively charged or neutral amino acid residues; x = 0 or 1, y = 0 or 1, and x + y = 1 or 2; c = 0 to 4, d = 0 to 4; and a = 0 to 18 and b = 0 to 18 with the proviso that when m = 0 at least one of B and Z is a positively charged amino acid residue and when n is 0 at least one of B and Z is a positively charged amino acid residue, and when m = n = 1 and y is 0 at least one of Z , B , B and Z is a positively charged amino acid residue and when m = n = 1 and x = 0 at least one of Z , B , B and Z is a positively charged amino acid residue: B and B may also represent a non-peptide spacer arm of a length equivalent to that determined by the length of b and c residues of amino acids.，下面是TREATMENT OF INFLAMMATORY DISEASES OF THE GASTRO-INTESTINAL TRACT专利的具体信息内容。
| 标题 | 发布/更新时间 | 阅读量 |
|---|---|---|
| 通过抑制α蛋白激酶1治疗炎症和相关疾病和病症的方法 | 2020-05-11 | 538 |
| 用于区分肠易激综合征与炎性肠病和乳糜泻的方法和系统 | 2020-05-12 | 615 |
| TLR7/8拮抗剂及其用途 | 2020-05-08 | 55 |
| 用于设计高效力糖皮质激素的结构与机制 | 2020-05-16 | 906 |
| 用于细胞植入的补片植入物组合物 | 2020-05-08 | 355 |
| 作为白介素-1活性抑制剂的化合物 | 2020-05-17 | 686 |
| 作为IRAK4抑制剂的二环杂环衍生物 | 2020-05-11 | 237 |
| 抗PD-1抗体及其用途 | 2020-05-16 | 559 |
| γC细胞因子活性的稳定调节剂 | 2020-05-15 | 423 |
| 芳烃受体拮抗剂及其用途 | 2020-05-12 | 639 |
高效检索全球专利专利汇是专利免费检索,专利查询,专利分析-国家发明专利查询检索分析平台，是提供专利分析，专利查询，专利检索等数据服务功能的知识产权数据服务商。
我们的产品包含105个国家的1.26亿组数据，免费查、免费专利分析。
专利汇分析报告产品可以对行业情报数据进行梳理分析，涉及维度包括行业专利基本状况分析、地域分析、技术分析、发明人分析、申请人分析、专利权人分析、失效分析、核心专利分析、法律分析、研发重点分析、企业专利处境分析、技术处境分析、专利寿命分析、企业定位分析、引证分析等超过60个分析角度，系统通过AI智能系统对图表进行解读，只需1分钟，一键生成行业专利分析报告。
-
2 新治疗用途
