专利检索_ ....有3个键连杂原子其中最多有1个键连卤原子的碳原子专利检索_ ....有3个键连杂原子其中最多有1个键连卤原子的碳原子专利检索查询

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C07D333/70： .....连在位置2

序号	专利名	申请号	申请日	公开（公告）号	公开（公告）日	发明人
321	Method for producing a thiophene compound	JP27196387	1987-10-29	JPH0813810B2	1996-02-14	ライナー・ハンプレヒト

322	JPH06503314A -	JP50033792	1991-12-03	JPH06503314A	1994-04-14
PCT No. PCT/EP91/02287 Sec. 371 Date Jun. 7, 1993 Sec. 102(e) Date Jun. 7, 1993 PCT Filed Dec. 3, 1991 PCT Pub. No. WO92/10094 PCT Pub. Date Jun. 25, 1992.A herbicidal composition containing one or more substituted 2-aminothiophenes of the formula I alkylene chain to which a benzene ring may be fused, R3 is -CN or CX-R6, where R6 is hydroxyl, C1-C4-alkoxy or amino, R4 is hydrogen or a phenyl group which may carry one or two nitro radicals, -PO(OR8)2, -CX-R9, -SO2R10, -CX-N(H) -CO-R8 or -CX-N(R7)-SO2-R11, where R8 is hydrogen, C1-C4-alkyl or phenyl group R9 is C1-C20-alkyl, partially or completely halogenated C1-C6-alkyl, C2-C6-alkenyl, C6-cycloalkyl, or amino, C1-C4-alkylamino, C3-C8-cycloalkylamino, phenyl or phenylamino, where the aromatic moiety may carry at least one of nitro and halogen; R10 is C1-C4-alkyl or phenyl, which may carry one C1-C4-alkyl radical; R11 is pyrrolidin-1-yl, piperidin-1-yl, morpholin-4-yl or piperazin-1-yl, where the heterocyclic structures may carry one C1-C4-group; R5 is hydrogen; or R4 and R5 together form a group =CR12R13 or -CO-W-CO-, where R12 is hydrogen, amino, C1-C4-alkylamino or C3-C8-cycloalkylamino; R13 is amino, C3-C8-cycloalkylamino, phenyl or pyridyl, where the two last mentioned substituents may carry at least one halogen or nitro radicals; W is an ethylene or ethenylene bridge, or a 6-membered 1,2-C-bonded aromatic bridge where these bridge members may carry, on each substitutable carbon atom, at least one halogen a 5-membered or 6-membered 1,2-C-bonded cycloalkylene or cycloalkenylene bridge, and the basic salts of the compounds I in which R3 is hydroxycarbonyl or hydroxythiocarbonyl, and the acidic salts of the compounds I which contain a basic nitrogen atom, as antagonistic compounds and one or more herbicidal active ingredients from the group consisting of the cyclohexenone derivatives of the formula III III
323	Phenyl derivative	JP3525492	1992-02-21	JPH05112515A	1993-05-07	NARUTO SHUNJI; SUGANO YUICHI; MATSUDA KEIICHI; SUGIMOTO MASAHIKO; ODA TOMIICHIROU
PURPOSE: To obtain a novel phenyl derivative having excellent action to produce or stimulate the secretion of nerve grow factors with reduced side effects. CONSTITUTION: A compound of formula I [R ¹ is nitro, amino (substitutible with alkyls or cycloalkyls), protected amino; R ² is amino, protected amino, OH or the like; R ³ is amino which can be substituted with alkyls or the like, heterocyclic ring bonding through an N atoms to the ring; m is 0 to 2; n is 0 to 6 where n is 2 to 6, when m=0] and its salts: for example, N-(1- adamantyl)-(4-acetoxy-3-nitro)cinnamic amide. The compound of formula I is obtained by reaction of a reactive derivative of a carboxylic acid of formula II (Y is an eliminating group; R ¹' is a part of R ¹; R ²' is a part of P ²) with a compound of formula III in the presence of a base in an inert solvent, followed by reduction of the nitro into amino group, when R ¹' is nitro, if desired, and deprotection, when the amino or hydroxy group is protected. COPYRIGHT: (C)1993,JPO&Japio
324	JPH0446275B2 -	JP1686683	1983-02-02	JPH0446275B2	1992-07-29	ANTON SUTEYUUTSU
Benzothienyldialkylallylamines wherein the amine side chain is attached to the ring via an alkyl radical and is either in 4-, 5-, 6- or 7-position or if not bears tertiary alkylethynyl or alkenylethynyl as its terminal group, which are useful, in particular, as anti-mycotic agents.
325	Sulfamoylphenyl urea	JP27362589	1989-10-20	JPH02174754A	1990-07-06	URUSU BURUKUHARUTO; RAAFUATO ZORIMAN; UERUNAA TOETSUPUFURU; HANSUURUDORUFU BUAESUPE
NEW MATERIAL: A compd. represented by formula I [wherein A is a group represented by formula II (wherein R ^g, R ^h are each H or a halogen; and R ^c is H or a halogen); R ¹ and R ² are H or a 1-8C alkyl; R ³ is H or a 1-4C alkyl; and R ^a and R ^b are each H or a halogen]. EXAMPLE: 1-[4-(N-3,4-Dimethylbenzoylsulfamoyl)-phenyl]-3-methyl urea. USE: A plant protecting agent. An agricultural plant is protected from crop injury action of an acylcyclohexanedione herbicide or a sulfonyl urea herbicide. PROCESS: An isocyanate represented by formula IV is reacted with a sulfamoylaniline represented by formula III to obtain the compd. represented by formula I. COPYRIGHT: (C)1990,JPO
326	Parasite control	JP15069389	1989-06-15	JPH02152922A	1990-06-12	KEISU DOUMONTO UINGU
PURPOSE: To control parasite on human and animal by bringing parasite into contact with a specific N'-substituted N,N'-disubstituted hydrazine. CONSTITUTION: The parasite is brought into contact with the compound expressed by the formula [A', B', D are each an optional atom or atom group independently; E is a tertiary carbon containing an organic group, a non-tertiary carbon containing a haloalkyl or an organic metal group; the one G ₁ is C, N, O, S, both the G ₂s and the other G ₁ are each C, or the one G ₂ is S, P and both the G ₁s and the other G ₂ are each C; when G ₂ adjacent to D is S then the D-G ₂ bond is a double bond and the G ₂-N bond is a single bond; A'-G ₁ and G ₁-B' bonds are each independently a single bond, a double bond, an aromatic bond; N-E bond is a N-C single bond, with the proviso that when B' is =CHC ₆H ₅ then E is not C(O)CH=CHC ₆H ₅] or their salts, for example N'-t- butyl-N,N'-(4-chlorobenzoyl)hydrazine to be controlled. COPYRIGHT: (C)1990,JPO
327	Production of thiophene compound	JP27196387	1987-10-29	JPS63126874A	1988-05-30	RAINAA HANPUREHITO

328	Benzothiophene derivative	JP17987287	1987-07-17	JPS6333328A	1988-02-13	JIRU AN PANETSUTA

329	Novel compound, manufacture and medicinal composition	JP30115586	1986-12-17	JPS62175466A	1987-08-01	DENISU JIEIMUZU AUTORETSUDO

330	Thionooxazines, production and use thereof	JP26286986	1986-11-06	JPS62114989A	1987-05-26	BERUNAA HARENBATSUHA; HANSU RINDERU; FURIIDORITSUHI BERUSHIYAUAA; MARUTEIN SHIEERU; ANNO DE YONGU

331	Use of thienylamine as production promoter and novel thienylamine	JP21985986	1986-09-19	JPS6272684A	1987-04-03	BERUNAA HARENBATSUHA; HANSU RINDERU; FURIIDORITSUHI BERUSHIYAUAA; MARUTEIN SHIEERU; ANNO DE YONGU

332	Production promoter	JP14501586	1986-06-23	JPS624259A	1987-01-10	BERUNAA HARENBATSUHA; HANSU RINDERU; FURIIDORITSUHI BERUSHIYAUAA; MARUTEIN SHIEERU; ANNO DE YONGU
The present invention relates to the use of substituted ureas and isoureas of the formulae Ia and Ib in which R<1>-R<5> and X are as defined in the description as growth promoters for animals, novel substituted ureas and isoureas, and their preparation.
333	JPS61343B2 -	JP12178776	1976-10-08	JPS61343B2	1986-01-08	SHII DEIBITSUDO JOONZU; TORIO SUAREZU

334	Novel sterile agent	JP12178776	1976-10-08	JPS5253851A	1977-04-30	SHII DEIBITSUDO JIYOONZU; TOURIO SUAREZU

335	Benzo b chiofuenjudotainoseizoho	JP6902175	1975-06-06	JPS516958A	1976-01-20	MARUSERU DEKAN; JAN GUUBAN
Novel benzo[b]thiophene derivatives corresponding to the general formula: I and the pharmaceutically acceptable acid addition salts thereof, wherein R represents a branched- or straight-chain alkyl group containing from 1 to 4 carbon atoms, or a cyclohexyl group, n is an integer in the range of from 3 to 6 inclusive, and Am represents a dimethylamino, diethylamino, di-n-propylamino or di-n-butylamino group.
336	JPS4944031A -	JP7445873	1973-07-03	JPS4944031A	1974-04-25

337	JPS4891128A -	JP1485173	1973-02-07	JPS4891128A	1973-11-27

338	COMPOUNDS FOR THE TREATMENT OF HEPATITIS C	PCT/US2009055648	2009-09-02	WO2010030538A3	2010-05-06	PRACITTO RICHARD; KADOW JOHN F; BENDER JOHN A; BENO BRETT R; GRANT-YOUNG KATHARINE A; HAN YING; HEWAWASAM PIYASENA; NICKEL ANDREW; PARCELLA KYLE E; YEUNG KAP-SUN; CHUPAK LOUIS S
The disclosure provides compounds of formula I, II, III, IV, and V, including their salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV.
339	ANTIBACTERIAL DRUG FOR TREATMENT OF STAPHYLOCOCCUS AUREUS AND OTHER GRAM-POSITIVE BACTERIAL INFECTIONS	PCT/US2009039023	2009-03-31	WO2009124086A3	2010-02-25	DAI DONGCHENG; HRUBY DENNIS E; BOLKEN TOVE C; WILSON REBECCA L; JONES KEVIN F; JORDON ROBERT
Compounds, methods and pharmaceutical compositions for treating bacterial infections, by administering certain compounds in therapeutically effective amounts are disclosed. Methods for preparing the compounds and methods of using the compounds and pharmaceutical compositions thereof are also disclosed. In particular, the treatment and prophylaxis of bacterial infections such as caused by the Staphylococcus aureus family is disclosed.
340	INHIBITORS OF CALCIUM-ACTIVATED CHLORIDE CHANNELS	PCT/US2008086600	2008-12-12	WO2009079373A2	2009-06-25	VERKMAN ALAN S; DE LA FUENTE GONZALEZ RICARDO
Provided herein are methods for identifying compounds that are inhibitors of a calcium-activated chloride channel. Aminothiophene and aminothiazole compounds, and compositions comprising these compounds, described herein that inhibit efflux of chloride through a calcium-activated chloride channel are useful for treating diseases, disorders, and sequelae of diseases, disorders, and conditions that are associated with aberrantly increased chloride and fluid secretion, for example, secretory diarrhea.

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