序号 | 专利名 | 申请号 | 申请日 | 公开(公告)号 | 公开(公告)日 | 发明人 |
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1 | 在一个反应容器中标记和纯化存在于要处理的生物学样品中的感兴趣核酸的方法 | CN200580030012.8 | 2005-07-21 | CN101018801A | 2007-08-15 | A·勒扬; L·梅诺; F·奇诺特 |
本发明涉及标记和纯化存在于要处理的生物学样品中的感兴趣核酸的方法,包括:提供单一一个反应容器;将以下物质导入所述反应容器:-所述生物学样品,-至少一种标记核酸的试剂,-能够吸附这些核酸的至少一种固体支持物,和-对于标记所述核酸和/或对于将这些核酸固定在所述支持物上所必需的所有成分;温育所述反应容器的内容物;和分离经标记的核酸。本发明优选用于诊断领域。 | ||||||
2 | PROCEDE DE MARQUAGE ET DE PURIFICATION D'ACIDES NUCLEIQUES D'INTERET PRESENTS DANS UN ECHANTILLON BIOLOGIQUE A TRAITER DANS UN UNIQUE RECIPIENT REACTIONNEL | EP05792074.6 | 2005-07-21 | EP1778713B1 | 2008-12-31 | LAAYOUN, Ali; MENOU, Lionel; GINOT, Frédéric |
The invention relates to a method for labeling and purifying nucleic acids of interest present in a biological sample to be treated, consisting of: providing a single reaction vessel; introducing, into the reaction vessel, the biological sample, at least one reagent for labeling nucleic acids, at least one solid support enabling the adsorption of these nucleic acids, and all ingredients necessary for labeling the nucleic acids and/or for immobilizing these nucleic acids on the support; incubating the contents of the reaction vessel, and; isolating the labeled nucleic acids. The invention is preferably for use in the field of diagnostics. | ||||||
3 | PROCEDE DE MARQUAGE ET DE PURIFICATION D'ACIDES NUCLEIQUES D'INTERET PRESENTS DANS UN ECHANTILLON BIOLOGIQUE A TRAITER DANS UN UNIQUE RECIPIENT REACTIONNEL | EP05792074.6 | 2005-07-21 | EP1778713A2 | 2007-05-02 | LAAYOUN, Ali; MENOU, Lionel; GINOT, Frédéric |
The invention relates to a method for labeling and purifying nucleic acids of interest present in a biological sample to be treated, consisting of: providing a single reaction vessel; introducing, into the reaction vessel, the biological sample, at least one reagent for labeling nucleic acids, at least one solid support enabling the adsorption of these nucleic acids, and all ingredients necessary for labeling the nucleic acids and/or for immobilizing these nucleic acids on the support; incubating the contents of the reaction vessel, and; isolating the labeled nucleic acids. The invention is preferably for use in the field of diagnostics. | ||||||
4 | Hypoglycemic 5-substituted oxazolidine-2,4-diones | US353777 | 1982-03-01 | US4423233A | 1983-12-27 | Rodney C. Schnur |
Hypoglycemic 5-furyl and 5-thienyl derivatives of oxazolidine-2,4-dione and the pharmaceutically-acceptable salts thereof; certain 3-acylated derivatives thereof; and intermediates useful in the preparation of said compounds. | ||||||
5 | Herbicidal sulfonamides | US824805 | 1977-08-15 | US4127405A | 1978-11-28 | George Levitt |
N-(1,3,5-triazin-2-ylaminocarbonyl) arylsulfonamides, such as N-[(4,6-dimethyl-1,3,5-triazin-2-yl)aminocarbonyl]benzenesulfonamide, are useful for the regulation of plant growth and as herbicides, particularly for controlling nutsedge. | ||||||
6 | Herbicidal sulfonamides | US829823 | 1977-09-01 | US4120691A | 1978-10-17 | George Levitt |
Novel N-(1,2,4-triazin-3-ylaminocarbonyl) arylsulfonamides, such as N-[(5,6-dimethyl-1,2,4-triazin-3-yl)aminocarbonyl]benzene sulfonamide, are useful for regulating the growth of plants. | ||||||
7 | Present in a biological sample to be processed in a single reaction vessel, the target nucleic acid labeling and purification process | JP2007521998 | 2005-07-21 | JP2008507263A | 2008-03-13 | フレデリック ジノ,; リオネル ムヌ,; アリ ラーヨウン, |
【課題】単一の反応槽において処理される生体試料中に存在する、標的の核酸の標識及び精製方法の提供。
【解決手段】本発明は、処理される生体試料中に存在する標的の核酸の標識及び精製方法であって、 以下: ・単一の反応槽の使用、 ・生体試料、核酸用の少なくとも1つの標識試薬、上記核酸を吸着できる少なくとも1つの固体支持体、並びに、核酸の標識及び/又は支持体上への上記核酸の固定に必要な任意の成分の、反応槽中への導入、 ・反応槽内容物のインキュベート、並びに、 ・上記で標識された核酸の分離:を含むことを特徴とする方法に関する。 本発明は、診断分野で使用されることが好ましい。 【選択図】なし |
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8 | Novel nnalkoxyydithienylpiperidine*its manufacture and medicine containing same and having antihistamic bronchial tree antispasmodic activity | JP314780 | 1980-01-17 | JPS55100381A | 1980-07-31 | YURUGEN ENGERU; AKUSERU KUREEMAN; UTE ATSUHATAARAATO TSUTSUKAAMA; KURAUSU TEIIMAA |
9 | Palladium catalyzed reactions executed on solid-phase peptide synthesis supports for the production of self-assembling peptides embedded with complex organic electronic subunits | US14524845 | 2014-10-27 | US09234003B2 | 2016-01-12 | John D. Tovar; Allix M. Sanders |
Methods to synthesize self-assembling peptides embedded with complex organic electronic subunits are provided. | ||||||
10 | Palladium Catalyzed Reactions Executed on Solid-Phase Peptide Synthesis Supports for the Production of Self-Assembling Peptides Embedded with Complex Organic Electronic Subunits | US14524845 | 2014-10-27 | US20150112044A1 | 2015-04-23 | John D. Tovar; Allix M. Sanders |
Methods to synthesize self-assembling peptides embedded with complex organic electronic subunits are provided. | ||||||
11 | Palladium catalyzed reactions executed on solid-phase peptide synthesis supports for the production of self-assembling peptides embedded with complex organic electronic subunits | US13657219 | 2012-10-22 | US08871903B2 | 2014-10-28 | John D. Tovar; Allix M. Sanders |
Methods to synthesize self-assembling peptides embedded with complex organic electronic subunits are provided. | ||||||
12 | N-Alkoxy-dithienylpiperidines, pharmaceutical compositions thereof and methods of use thereof | US112100 | 1980-01-14 | US4263308A | 1981-04-21 | Jurgen Engel; Axel Kleemann; Ute-Achterrath Tuckermann; Klaus Thiemer |
There are prepared compounds of the formula ##STR1## where R.sub.1 is hydrogen or hydroxy, R.sub.2 is hydrogen or R.sub.1 and R.sub.2 together represent a second bond between the carbon atoms carrying R.sub.1 and R.sub.2, Alk is a C.sub.2 -C.sub.6 alkylene group, R.sub.3 is a C.sub.3 -C.sub.8 -cycloalkyl group, a C.sub.1 -C.sub.6 -alkyl group, a C.sub.1 -C.sub.6 -hydroxyalkyl group or a C.sub.2 -C.sub.6 -hydroxyalkoxy-C.sub.1 -C.sub.6 -alkyl group and the groups R.sub.4, R.sub.5, R.sub.6 and R.sub.7 are the same or different and are hydrogen, C.sub.1 -C.sub.6 -alkyl group or halogen atoms, their N-oxides, their quaternary salts and their acid addition salts. There are also described processes for their production. The compounds have a strong bronchospasmolytic activity, antianaphylactic activity and an antihistamine-antiserotonine activity. | ||||||
13 | Sulphonated and neutralized hydrocarbon sulphur compounds | US39439529 | 1929-09-21 | US1996334A | 1935-04-02 | HESSLE ERIC T |
14 | Present in a biological sample to be processed in a single reaction vessel, the target nucleic acid labeling and purification process | JP2007521998 | 2005-07-21 | JP4651666B2 | 2011-03-16 | フレデリック ジノ,; リオネル ムヌ,; アリ ラーヨウン, |
15 | JPS6236029B2 - | JP3906277 | 1977-04-07 | JPS6236029B2 | 1987-08-05 | JOOJI REBITSUTO |
16 | Nn*heterocyclic aminocarbonyl*aryl sulfonamide and agricultural chemicals containing same | JP3906277 | 1977-04-07 | JPS52122384A | 1977-10-14 | LEVITT GEORGE |
17 | THIENODIAZEPINE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT | US15551926 | 2015-07-13 | US20180037589A1 | 2018-02-08 | Jung-Mi HAH; Jung Hun LEE; Minjung KIM |
The present invention relates to novel thienodiazepine derivatives or pharmaceutically acceptable salts thereof, and a pharmaceutical composition including the same. The thienodiazepine derivatives or pharmaceutically acceptable salts thereof exhibit selective inhibition activities against protein kinases such as c-Kit, FLT3, FMS, LYN, RAF1, VEGFR3, PDGFRa, PDGFRb, RET, etc., and thus can be used as a pharmaceutical composition for prevention or treatment of abnormal cell growth diseases. | ||||||
18 | Omniconjugated conductive polymers and methods for making the same | US13862609 | 2013-04-15 | US09058915B1 | 2015-06-16 | Peter Zarras; Alfred Baca; John D. Stenger-Smith; Andrew P. Chafin; William Lai |
A new class of polymers based upon the radialene group as the parent repeating group and characterized by the following general formula: where R1, R2, R3, R4 are each independently any pi electron conjugated group, but not limited to: pyrrole, thiophene, benzene, naphthalene, furan, ethene, aniline, and n is an integer from 2 to 20,000. Furthermore, the individual R groups can be further functionalized with an alky group having 1 to 22 carbons; alkoxy group having 1 to 22 carbons; alkyl sulfonate having 1 to 22 carbons; alkyl phosphate group containing 1 to 22 carbons, alkoxy phosphate group having 1 to 22 carbons; ethenylendioxy group; propylene dioxy group. | ||||||
19 | Palladium Catalyzed Reactions Executed on Solid-Phase Peptide Synthesis Supports for the Production of Self-Assembling Peptides Embedded with Complex Organic Electronic Subunits | US13657219 | 2012-10-22 | US20140114052A1 | 2014-04-24 | John D. Tovar; Allix M. Sanders |
Methods to synthesize self-assembling peptides embedded with complex organic electronic subunits are provided. | ||||||
20 | Process for Labeling and Purification of Nucleic Acids of Interest Present in a Biological Sample to be Treated in a Single Reaction Vessel | US11658028 | 2005-07-21 | US20080233632A1 | 2008-09-25 | Ali Laayoun; Lionel Menou; Frederic Ginot |
The present invention relates to a process for labeling and purification of nucleic acids of interest present in a biological sample to be treated, comprising: taking a single reaction vessel, introducing into the reaction vessel: the biological sample, at least one labeling reagent for nucleic acids, at least one solid support enabling the adsorption of said nucleic acids, any ingredient necessary for the labeling of the nucleic acids and/or for the immobilization of said nucleic acids on the support, incubating the contents of the reaction vessel, and isolating the nucleic acids thus labeled. The invention finds a preferred application in the diagnostics field. |