| 序号 | 专利名 | 申请号 | 申请日 | 公开（公告）号 | 公开（公告）日 | 发明人 |
|---|---|---|---|---|---|---|
| 101 | Methods of Generating Microparticles and Porous Hydrogels Using Microfluidics | US15335184 | 2016-10-26 | US20170145169A1 | 2017-05-25 | John OAKEY; Kaspars KRUTKRAMELIS; Bingzhao XIA |
| Provided herein are methods utilizing microfluidics for the oxygen-controlled generation of microparticles and hydrogels having controlled microparticle sizes and size distributions and products from provided methods. The included methods provide the generation of microparticles by polymerizing an aqueous solution dispersed in a non-aqueous continuous phase in an oxygen-controlled environment. The process allows for control of size of the size of the aqueous droplets and, thus, control of the size of the generated microparticles which may be used in biological applications. | ||||||
| 102 | Nanoparticle array comprising distributed nanoparticles | US13422741 | 2012-03-16 | US09540235B2 | 2017-01-10 | Radhakrishna Sureshkumar; Tao Cong; Satvik Wani |
| There is set forth herein a method for providing a nanoparticle array. A nanoparticle network can be provided by nanoparticles combined with surfactant micelle chains. The nanoparticle network can be provided by distributing metal nanoparticles in a surfactant solution and agitating the surfactant solution comprising the nanoparticles to form a gel comprising the nanoparticle network which can be characterized by a distributed array of nanoparticles combined with surfactant micelle chains within a fluid. The gel can comprise a fluid in a continuous phase and the nanoparticles in a discontinuous phase. Apparatus having arrays of nanoparticles are also set forth herein. | ||||||
| 103 | ANHYDROUS MULTIPHASE GEL SYSTEM | US15185210 | 2016-06-17 | US20160361252A1 | 2016-12-15 | Patrick Franke |
| An anhydrous multiphase gel system consisting of an outer lipid matrix and an inner phase gelled by means of a polymer is described, which can be obtained by a) Melting the lipid phase with the formation of a liquid lipid phase, b) Mixing and homogenizing polymers or polymer blends capable of swelling with the formation of a polymer phase to be dispersed, c) Combining the polymer phase with the liquid lipid phase and homogenizing the phases, and d) Cold stirring the phase mixture until a solid gel-like mixed structure of the entire system is formed. The anhydrous multiphase gel system is particularly suitable for taking up difficultly soluble active substances in high concentration and for providing topical and transdermal applications. The described system is called an EDRS, “Entrapped Drug Reservoir System”. | ||||||
| 104 | METHODS AND SYSTEMS FOR PRODUCING CARBON AEROGEL | US15033002 | 2013-10-31 | US20160244332A1 | 2016-08-25 | Chongjun Zhao; Jianbo Dong; Youfu Huang; Jingwei Ma; Xiuzhen Qian |
| Methods described herein generally relate to producing carbon aerogel. The method may include providing a carbon-containing polymeric material, and contacting the carbon-containing polymeric material with light, heat or both to produce the carbon aerogel. Systems and kits for producing carbon aerogel are also disclosed. | ||||||
| 105 | Carbon nanotube separation by reversible gelation | US13657659 | 2012-10-22 | US09114994B2 | 2015-08-25 | Seth Adrian Miller |
| Embodiments described herein generally relate to the separation of carbon nanotubes by reversible gelation. | ||||||
| 106 | Stabilizer composition of co-attrited microcrystalline cellulose and carboxymethylcellulose, method for making, and uses | US13573764 | 2012-10-04 | US09055757B2 | 2015-06-16 | Zheng Tan; Maurice Gerard Lynch; Thomas Ruszkay; Michael Sestrick |
| Methods of making a high gel strength, water-dispersible, stabilizing colloidal microcrystalline cellulose composition are disclosed. This stabilizer composition is useful in many food and non-food applications. | ||||||
| 107 | Assays and other reactions involving droplets | US14172266 | 2014-02-04 | US09017948B2 | 2015-04-28 | Jeremy Agresti; Liang-Yin Chu; David A. Weitz; Jin-Woong Kim; Amy Rowat; Morten Sommer; Gautam Dantas; George Church |
| The present invention generally relates to droplets and/or emulsions, such as multiple emulsions. In some cases, the droplets and/or emulsions may be used in assays, and in certain embodiments, the droplet or emulsion may be hardened to form a gel. In some aspects, a heterogeneous assay can be performed using a gel. For example, a droplet may be hardened to form a gel, where the droplet contains a cell, DNA, or other suitable species. The gel may be exposed to a reactant, and the reactant may interact with the gel and/or with the cell, DNA, etc., in some fashion. For example, the reactant may diffuse through the gel, or the hardened particle may liquefy to form a liquid state, allowing the reactant to interact with the cell. As a specific example, DNA contained within a gel particle may be subjected to PCR (polymerase chain reaction) amplification, e.g., by using PCR primers able to bind to the gel as it forms. As the DNA is amplified using PCR, some of the DNA will be bound to the gel via the PCR primer. After the PCR reaction, unbound DNA may be removed from the gel, e.g., via diffusion or washing. Thus, a gel particle having bound DNA may be formed in one embodiment of the invention. | ||||||
| 108 | COMPOSITION SIMULATING THE DIELECTRIC PROPERTIES OF THE HUMAN BODY AND USE THEREOF FOR SAR MEASUREMENT | US14361104 | 2012-11-29 | US20140368218A1 | 2014-12-18 | Kristell Quelever; Thibaud Coradin; Christian Bonhomme; Olivier Meyer; Benoit Derat |
| An oil-in-water emulsion includes an aqueous phase and an oily phase, the aqueous phase including water and a relaxing agent, and the oily phase including an oil and at least one surfactant. The emulsion has dielectric properties simulating dielectric properties of the human body. A device including the emulsion, a simulated human body part filled with the emulsion; and at least one system capable of measuring a local specific absorption rate when the simulated human body part is exposed to an electromagnetic field are also described. A method for conducting specific absorption rate tests of an apparatus radiating an electromagnetic field including using the emulsion, and a process for manufacturing the emulsion are also described. | ||||||
| 109 | SYSTEMS AND METHODS FOR HIGH-THROUGHPUT MICROFLUIDIC BEAD PRODUCTION | US13822983 | 2011-10-03 | US20130183246A1 | 2013-07-18 | Tza-Huei Wang; Weijie Beh; Dara L. Kraitchman; Hsa-Quan Mao |
| A system for producing microbeads includes a microfluidic device defining a supply channel and a shearing channel, a microbead precursor material disposed in the supply channel, a carrier fluid disposed in the shearing channel, and a pressure distribution system fluidly connected to each of the supply channel and the shearing channel to control at least relative pressures of the microbead precursor material and the carrier fluid. The supply channel includes a check valve adapted to be subjected to a bias pressure that is sufficient to close the check valve to flow of microbead precursor material when a supply pressure of the microbead precursor material is below a threshold pressure and is open to flow of the microbead precursor material when the supply pressure of the microbead precursor material is greater than the threshold pressure. An end of the supply channel opens into the shearing channel such that the microbead precursor material is sheared into droplets by the carrier fluid flowing through the shearing channel. A pressure of the carrier fluid is less than the bias pressure. The microbead precursor material and the carrier fluid are substantially immiscible. | ||||||
| 110 | Gel manufacturing apparatus | US12827106 | 2010-06-30 | US08313702B2 | 2012-11-20 | Katsuya Ide; Kei Hiruma |
| A gel manufacturing apparatus adapted to generate gel by making a first solution and a second solution react with each other includes: a flow mechanism adapted to make the second solution flow; an ejection mechanism having a nozzle plate provided with a nozzle adapted to eject the first solution to the second solution made to flow using a droplet ejection method; and a gap plate provided with a through hole communicated with the nozzle, wherein the gap plate is disposed between the flow mechanism and the ejection mechanism. | ||||||
| 111 | Carbon nanotube separation by reversible gelation | US12506148 | 2009-07-20 | US08308955B2 | 2012-11-13 | Seth Adrian Miller |
| Embodiments described herein generally relate to the separation of carbon nanotubes by reversible gelation. | ||||||
| 112 | Hydrogel particles | US12307294 | 2007-06-26 | US08222193B2 | 2012-07-17 | Kimitaka Tanaka; Satoshi Ueno; Koji Mine |
| The present invention relates to hydrogel particles containing bubbles and having a specific gravity of 0.7 to 1.00 and an average particle diameter of 50 to 500 μm, as well as a process for producing the same. The hydrogel particles may also contain hollow inorganic particles. | ||||||
| 113 | COMPOSITION AND PROCESS FOR PRODUCTION THEREOF | US13361150 | 2012-01-30 | US20120128749A1 | 2012-05-24 | Hideyasu Tsuji; Yasuhiro Tsuji; Toru Oka; Shigeru Sugi; Masumi Torii; Haruka Miyao; Yoshimitsu Nakayama; Tomoyuki Torii; Masahito Mori |
| Disclosed are: a composition which enables the more effective development of the efficacy of a water-soluble drug in a solution containing the drug; and a dispersion in which a hydrophobic drug can be dispersed stably without requiring the use of any surfactant. Specifically disclosed are: a composition comprising ultra-fine bubbles having a mode particle size of 500 nm or less, a drug and water; and a process for producing a composition comprising ultra-fine bubbles having a mode particle size of 500 nm or less, a drug and water, which utilizes an ultra-fine bubble generation apparatus. | ||||||
| 114 | EFFERVESCENT COMPOSITION FOR FORMING A GELLED COMPOSITION, TABLET FOR FORMING A GELLED COMPOSITION, AND METHOD OF MAKING A GELLED COMPOSITION | US13113174 | 2011-05-23 | US20110287114A1 | 2011-11-24 | Kyle M. Johnson |
| A method of making a gelled composition that includes combining water and an effervescent tablet in a vessel, the effervescent tablet including at least 200 mg gelatin and an effervescent couple that includes an acid and a base, heating an aqueous composition (e.g., in a microwave oven), optionally adding cold water to the heated composition, and chilling the composition for a period sufficient for the composition to form a gel. | ||||||
| 115 | Carbon Nanotube Seperation by Reversible Gelation | US12506148 | 2009-07-20 | US20110014113A1 | 2011-01-20 | Seth Adrian Miller |
| Embodiments described herein generally relate to the separation of carbon nanotubes by reversible gelation. | ||||||
| 116 | Anhydrous Multiphase Gel System | US11989968 | 2006-08-04 | US20100166681A1 | 2010-07-01 | Patrick Franke |
| An anhydrous multiphase gel system consisting of an outer lipid matrix and an inner phase gelled by means of a polymer is described, which can be obtained by a) Melting the lipid phase with the formation of a liquid lipid phase, b) Mixing and homogenizing polymers or polymer blends capable of swelling with the formation of a polymer phase to be dispersed, c) Combining the polymer phase with the liquid lipid phase and homogenizing the phases, and d) Cold stirring the phase mixture until a solid gel-like mixed structure of the entire system is formed. The anhydrous multiphase gel system is particularly suitable for taking up difficultly soluble active substances in high concentration and for providing topical and transdermal applications. The described system is called an EDRS, “Entrapped Drug Reservoir System”. | ||||||
| 117 | HYDROGEL PARTICLE | US12307294 | 2007-06-26 | US20090312213A1 | 2009-12-17 | Kimitaka Tanaka; Satoshi Ueno; Koji Mine |
| The present invention relates to hydrogel particles containing bubbles and having a specific gravity of 0.7 to 1.00 and an average particle diameter of 50 to 500 μm, as well as a process for producing the same. The hydrogel particles may also contain hollow inorganic particles. | ||||||
| 118 | Gel Yield Improvements | US11692752 | 2007-03-28 | US20080242747A1 | 2008-10-02 | Bruce Lucas; Glenn Weightman; Harold Walters; Jimmie Weaver; Steven Wilson; Billy Slabaugh |
| A process of increasing the viscosity of a gel, or the yield of a hydratable material includes heating a hydratable material, an aqueous component or both, prior to mixing the hydratable material with the aqueous component. In certain instances, the aqueous component is heated to a temperature of at least about 100° F., and the hydratable material component and the heated aqueous component are mixed together to form a gel in certain instances, the hydratable material component is heated to a temperature of at least about 100° F., and the heated hydratable material component and the aqueous component are mixed together to form a gel. | ||||||
| 119 | Hydrophobic starch derivatives | US11205721 | 2005-08-17 | US07157573B2 | 2007-01-02 | Pieter Lykle Buwalda; Ronald Peter W. Kesselmans; Augustinus Arnoldus M. Maas; Hylke Hotze Simonides |
| The invention relates to a process for preparing a hydrophobic starch, comprising etherification, esterification or amidation of a root or tuber starch comprising at least 95 wt. % of amylopectin, based on dry substance of the starch, or a derivative thereof, with a substituent comprising an alkyl chain having from 4–24 carbon atoms. The invention further relates to a hydrophobic starch obtainable by said process. | ||||||
| 120 | Encapsulated active material immobilized in hydrogel microbeads | US09425761 | 1999-10-22 | US06375968B1 | 2002-04-23 | Douglas Quong |
| A microbead comprising a hydrophilic matrix having active-filled microcapsules entrained therein. Compositions comprising the microbeads suspended in solution are useful for delivering active material. The microbeads of the invention may be controllable by exposing the microbeads to high or low humidity or moisture. | ||||||
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