| 序号 | 专利名 | 申请号 | 申请日 | 公开（公告）号 | 公开（公告）日 | 发明人 |
|---|---|---|---|---|---|---|
| 341 | Photoelectric endpoint detection | US3723062D | 1970-12-21 | US3723062A | 1973-03-27 | DAHMS H |
| A method and apparatus useful for colorimetric titration utilizes an indicator which changes from one colored form to another at or near an endpoint, and an optical endpoint detection system which generates signals responsive to the relative concentrations of the different colored forms of the indicator. The endpoint is indicated when the ratio of the logarithms of the signals reaches a predetermined value.
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| 342 | Inorganic phosphate assay,and reagents therefor | US3547586D | 1967-06-05 | US3547586A | 1970-12-15 | DENNEY JERRY W; DENNEY LARRY W |
| 343 | Colorimetric method for determining iron in blood | US3506404D | 1967-12-19 | US3506404A | 1970-04-14 | EVANS GEORGE; SEARCY RONALD |
| 344 | Quantitative determination of serum calcium | US3457045D | 1966-04-25 | US3457045A | 1969-07-22 | FRAGUADA JOSE M; BEAU ROBERT W LE |
| 345 | Method and apparatus for determining iodine in organic and biological materials | US28917963 | 1963-06-20 | US3235336A | 1966-02-15 | GEORGE MATSUYAMA |
| 346 | Diagnostic formulation for ph determination | US17645462 | 1962-02-28 | US3122420A | 1964-02-25 | REBAR JR JOHN; OAKES PAUL W; FREEBY WAYNE A |
| 347 | Urine calcium test | US43563954 | 1954-06-09 | US2824842A | 1958-02-25 | HIRSH SULKOWITCH |
| 348 | Thionin dye-ion exchange resin indicator compounds | US51178655 | 1955-05-27 | US2794786A | 1957-06-04 | SEGAL HARRY L; MILLER LEON L |
| 349 | Ion exchange resin indicator compound | US21269851 | 1951-02-24 | US2791533A | 1957-05-07 | SEGAL HARRY L; MILLER LEON L |
| 350 | Method for the determination of potassium | US7707325 | 1925-12-22 | US1849960A | 1932-03-15 | ELMER SHERRILL |
| 351 | Fluorescent protein sensors for measuring the pH of a biological sample | US94359 | 1998-06-09 | US6140132A | 2000-10-31 | Roger Y. Tsien; Atsushi Miyawaki; Juan Llopis |
| Disclosed are fluorescent protein sensors for measuring the pH of a sample, nucleic acids encoding them, and methods of use. The preferred fluorescent protein sensors are variants of the green fluorescent protein (GFP) from Aequorea victoria. Also disclosed are compositions and methods for measuring the pH of a specific region of a cell, such as the mitochondrial matrix or the Golgi lumen. | ||||||
| 352 | Bioluminescent bioreporter integrated circuit | US978439 | 1997-11-25 | US6117643A | 2000-09-12 | Michael L. Simpson; Gary S. Sayler; Michael J. Paulus |
| Disclosed are monolithic bioelectronic devices comprising a bioreporter and an OASIC. These bioluminescent bioreporter integrated circuit are useful in detecting substances such as pollutants, explosives, and heavy-metals residing in inhospitable areas such as groundwater, industrial process vessels, and battlefields. Also disclosed are methods and apparatus for environmental pollutant detection, oil exploration, drug discovery, industrial process control, and hazardous chemical monitoring. | ||||||
| 353 | Method and apparatus for detecting amine producing organisms in the vagina | US118502 | 1998-07-17 | US6117090A | 2000-09-12 | James C. Caillouette |
| A method of detecting pathogenic bacteria in the vagina, includes providing a vaginal moisture receiver receivable into the vagina; providing a reactant which changes color when contacted by moisture containing pathogenic bacteria; receiving vaginal moisture on the receiver; and contacting reactant with vaginal moisture on the receiver, whereby a change in color at the receiver indicates the presence of pathogenic bacteria. | ||||||
| 354 | Reagent for determining the ionic strength and/or the specific weight of aqueous liquids and method | US950981 | 1997-10-15 | US6114170A | 2000-09-05 | Klaus Habenstein |
| The invention relates to a method for determining the ionic strength and/or the specific weight of aqueous liquids and a reagent for this purpose, the composition of the reagent being such that the color change indicating the ionic strength is essentially directly dependent on the specific weight of the liquid to be determined and not on a pH shift. | ||||||
| 355 | Method of making a pH and amine test element | US040151 | 1998-03-17 | US6113856A | 2000-09-05 | Paul J. Lawrence; Peter U. Ly; David R. Shockey |
| Tests for elevated pH and volatile amines in aqueous fluids are disclosed, including tests useful in the diagnosis of bacterial vaginosis and in other biological conditions. By using formulated indicators and indicators held in matrices that are permeable to gas but not to liquid, the tests provide clear and sharp transitions detectable by visual or machine-readable means rather than by subjective judgments such as small gradations in color or olfactory determinations. The tests lend themselves readily to iconic readouts of the test indications and to the inclusion of positive and negative controls. | ||||||
| 356 | Estrogen or estradiol need determination by vaginal acidity determination | US848906 | 1997-05-01 | US6083178A | 2000-07-04 | James C. Caillouette |
| In the method of determining need for human estrogen or estradiol level change, the steps include determining local acidity proximate a moist wall surface of the vagina, as differing from desired threshold level, and administering sufficient estrogen or estradiol to result in change in acidity toward such level. | ||||||
| 357 | Diagnostic test for vaginal infections | US985233 | 1997-12-04 | US06019734A | 2000-02-01 | Chris Parkinson |
| An apparatus, method and diagnostic kit for assessing the presence or absence of a vaginal infection including bacterial vaginosis which includes a pH indicator means and a KOH patch for detecting bacterially derived amines. A method, apparatus and test kit for diagnosing vaginosis in a simple test series which can be readily performed in a doctor's office at the time a vaginal fluid sample is taken. | ||||||
| 358 | Vaginal multiple condition detection apparatus and method | US072257 | 1998-05-04 | US6013036A | 2000-01-11 | James C. Caillouette |
| In apparatus for detecting first and second conditions in the vagina or urethra, the combination comprising an elongated carrier insertible endwise into the vagina; first structure at a first location on the carrier for use in detecting the first condition, and second structure at a second location on the carrier for use in detecting the second condition, portions of first and second structures being inserted into the vagina or urethra, by manipulation of the carrier, and to be subsequently withdrawn, for use in detecting conditions. | ||||||
| 359 | Test piece and method of use for measuring magnesium in biological fluid | US827247 | 1997-03-28 | US5968833A | 1999-10-19 | Hitoshi Furuta; Shinzo Yoshida; Junji Yoshioka; Hisashi Ashida |
| A dry test piece for measuring a magnesium concentration in a biological fluid, which comprises the following reagent components (i) to (iii): (i) o-cresolphthalein complexon; (ii) O,O'-bis(2-aminophenyl)ethylene glycol-N,N,N',N'-tetraacetic acid; and (iii) a pH buffer agent of pH 8.5 to 11.0. | ||||||
| 360 | Calcium receptor-active molecules | US943986 | 1997-10-03 | US5962314A | 1999-10-05 | Edward M. Brown; Steven C. Hebert; James E. Garrett, Jr. |
| The present invention relates to the different roles inorganic ion receptors have in cellular and body processes. The present invention features: (1) molecules which can modulate one or more inorganic ion receptor activities, preferably the molecule can mimic or block an effect of an extracellular ion on a cell having an inorganic ion receptor, more preferably the extracellular ion is Ca.sup.2+ and the effect is on a cell having a calcium receptor; (2) inorganic ion receptor proteins and fragments thereof, preferably calcium receptor proteins and fragments thereof; (3) nucleic acids encoding inorganic ion receptor proteins and fragments thereof, preferably calcium receptor proteins and fragments thereof; (4) antibodies and fragments thereof, targeted to inorganic ion receptor proteins, preferably calcium receptor protein; and (5) uses of such molecules, proteins, nucleic acids and antibodies. | ||||||
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