1 |
Live attenuated catfish vaccine and method of making |
US15171367 |
2016-06-02 |
US09700611B2 |
2017-07-11 |
Mark L. Lawrence; Attila Karsi |
Live attenuated bacteria vaccines against enteric septicemia of fish, especially catfish, and methods related to the same. Mutant strains of the bacteria Edwardsiella ictaluri (a pathogenic bacterial strain of Enterobacteriaceae) are provided. The mutant Edwardsiella ictaluri bacteria (or other pathogenic bacterial strain of Enterobacteriaceae) contain one or more gene deletions or disruptions that result in less virulent bacterial strains as live attenuated vaccine compositions against virulent wild-type Edwardsiella ictaluri bacteria (or other pathogenic bacterial strain of Enterobacteriaceae). The mutant strains showing the best immunological protection and safety as a vaccine are the triple mutants ESC-NDKL1 (ΔgcvPΔsdhCΔfrdA) strain and ESC-NDKL2 (ΔgcvPΔsdhCΔmdh) strain, with the ESC-NDKL1 strain providing the greatest safety and efficacy of these two triple mutants. |
2 |
METHODS FOR CONFERRING OR ENHANCING HERBICIDE RESISTANCE ON PLANTS AND/OR ALGA WITH PROTOPORPHYRINOGEN OXIDASE VARIANTS |
US15532194 |
2015-12-16 |
US20170327837A1 |
2017-11-16 |
Soon-Kee SUNG; Joonseon YOON; Yunjung HAN |
Provided are methods for conferring and/or enhancing herbicide resistance on plants or algae including agricultural crops by introducing prokaryote-derived protoporphynnogen oxidase variants. |
3 |
PRODUCTION OF CHIRAL 1,2-AMINO ALCOHOLS AND ALPHA-AMINO ACIDS FROM ALKENES BY CASCADE BIOCATALYSIS |
US15257223 |
2016-09-06 |
US20170067084A1 |
2017-03-09 |
Zhi Li; Shuke Wu |
Disclosed herein are methods of forming chiral 1,2-aminoalcohols and α-aminoacids from alkene starting materials by way of an enzymatic cascade reaction sequence that may be accomplished in a single reaction vessel without the need to isolate any intermediates. Also disclosed herein are recombinant nucleic acids, vectors and host cells for use in the methods of the invention. |
4 |
LIVE ATTENUATED CATFISH VACCINE AND METHOD OF MAKING |
US15171367 |
2016-06-02 |
US20160339093A1 |
2016-11-24 |
Mark L. Lawrence; Attila Karsi |
Live attenuated bacteria vaccines against enteric septicemia of fish, especially catfish, and methods related to the same. Mutant strains of the bacteria Edwardsiella ictaluri (a pathogenic bacterial strain of Enterobacteriaceae) are provided. The mutant Edwardsiella ictaluri bacteria (or other pathogenic bacterial strain of Enterobacteriaceae) contain one or more gene deletions or disruptions that result in less virulent bacterial strains as live attenuated vaccine compositions against virulent wild-type Edwardsiella ictaluri bacteria (or other pathogenic bacterial strain of Enterobacteriaceae). The mutant strains showing the best immunological protection and safety as a vaccine are the triple mutants ESC-NDKL1 (ΔgcvPΔsdhCΔfrdA) strain and ESC-NDKL2 (ΔgcvPΔsdhCΔmdh) strain, with the ESC-NDKL1 strain providing the greatest safety and efficacy of these two triple mutants. |
5 |
プロトポルフィリノーゲンオキシダーゼ変異体を用いた植物及び/又は藻類の除草剤抵抗性付与又は増進方法 |
JP2017533480 |
2015-12-16 |
JP2018500909A |
2018-01-18 |
ソン・スンギ; ユン・チュンソン; ハン・ユンチョン |
原核生物から由来したプロトポルフィリノーゲンオキシダーゼ(Protoporphyrinogen oxidase)変異体を用いて植物又は藻類の除草剤抵抗性付与及び/又は増進させる方法が提供される。【選択図】図18 |
6 |
프로토포르피리노겐 옥시다아제를 이용한 식물 및/또는 조류의 제초제 저항성 부여 또는 증진 방법 |
KR1020160169920 |
2016-12-13 |
KR1020160146629A |
2016-12-21 |
성순기; 윤준선; 한윤정 |
원핵생물에서유래한프로토포르피리노겐옥시다아제(Protoporphyrinogen oxidase)를이용하여식물및/또는조류(algae)의제초제에대한저항성을부여및/또는증진시키는발명이제공된다. |
7 |
프로토포르피리노겐 옥시다아제를 이용한 식물 및/또는 조류의 제초제 저항성 부여 또는 증진 방법 |
KR1020150180467 |
2015-12-16 |
KR1020160073340A |
2016-06-24 |
성순기; 윤준선; 한윤정 |
원핵생물에서유래한프로토포르피리노겐옥시다아제(Protoporphyrinogen oxidase)를이용하여식물및/또는조류(algae)의제초제에대한저항성을부여및/또는증진시키는발명이제공된다. |
8 |
프로토포르피리노겐 옥시다아제를 이용한 식물 및/또는 조류의 제초제 저항성 부여 또는 증진 방법 |
KR1020160169920 |
2016-12-13 |
KR101862795B1 |
2018-07-04 |
성순기; 윤준선; 한윤정 |
원핵생물에서유래한프로토포르피리노겐옥시다아제(Protoporphyrinogen oxidase)를이용하여식물및/또는조류(algae)의제초제에대한저항성을부여및/또는증진시키는발명이제공된다. |
9 |
프로토포르피리노겐 옥시다아제를 이용한 식물 및/또는 조류의 제초제 저항성 부여 또는 증진 방법 |
KR1020150180467 |
2015-12-16 |
KR101827545B1 |
2018-02-08 |
성순기; 윤준선; 한윤정 |
원핵생물에서유래한프로토포르피리노겐옥시다아제(Protoporphyrinogen oxidase)를이용하여식물및/또는조류(algae)의제초제에대한저항성을부여및/또는증진시키는발명이제공된다. |