| 序号 | 专利名 | 申请号 | 申请日 | 公开（公告）号 | 公开（公告）日 | 发明人 |
|---|---|---|---|---|---|---|
| 1 | 产生1,3-丁二烯的方法 | CN201280040122.2 | 2012-06-15 | CN103842513A | 2014-06-04 | P.S.珀尔曼; 陈昌林; A.L.波特斯 |
| 本发明公开了用于从一种或多种的数种不同原料中产生1,3-丁二烯的方法，所述原料包括生物来源的原料、可再生原料、石油化学品原料和天然气。 | ||||||
| 2 | 产生1,3‑丁二烯的方法 | CN201280040122.2 | 2012-06-15 | CN103842513B | 2017-05-17 | P.S.珀尔曼; 陈昌林; A.L.波特斯 |
| 本发明公开了用于从一种或多种的数种不同原料中产生丁二烯的方法，所述原料包括生物来源的原料、可再生原料、石油化学品原料和天然气。 | ||||||
| 3 | Methods of producing four carbon molecules | US13524973 | 2012-06-15 | US09663801B2 | 2017-05-30 | Paul S. Pearlman; Changlin Chen; Adriana L. Botes |
| Disclosed are methods for producing butadiene from one or more of several diverse feedstocks including bioderived feedstocks, renewable feedstocks, petrochemical feedstocks and natural gas. | ||||||
| 4 | METHODS FOR BIOSYNTHESIZING 1,3 BUTADIENE | US13691623 | 2012-11-30 | US20130189753A1 | 2013-07-25 | Paul S. Pearlman; Changlin Chen; Adriana L. Botes; Alex Van Eck Conradie |
| This document describes biochemical pathways for producing butadiene by forming two vinyl groups in a butadiene synthesis substrate. These pathways described herein rely on enzymes such as mevalonate diphosphate decarboxylase, isoprene synthase, and dehydratases for the final enzymatic step. | ||||||
| 5 | METHODS OF PRODUCING FOUR CARBON MOLECULES | US15493431 | 2017-04-21 | US20180023097A1 | 2018-01-25 | Paul S. Pearlman; Changlin Chen; Adriana Leonora Botes |
| Disclosed are methods for producing butadiene from one or more of several diverse feedstocks including bioderived feedstocks, renewable feedstocks, petrochemical feedstocks and natural gas. | ||||||
| 6 | Pathways to adipate semialdehyde and other organic products | US14418543 | 2013-09-20 | US09809833B2 | 2017-11-07 | Man Kit Lau; Christopher P. Mercogliano |
| Recombinant microorganisms comprising at least one exogenous nucleic acid sequence and capable of producing adipate semialdehyde are provided. Adipate semialdehyde may be produced in a synthesis pathway utilizing a single thiolase reaction. Adipate semialdehyde may also be produced from intermediates consisting of alpha, omega difunctional aliphatic organic molecules. Methods of using recombinant microorganisms to produce 6-aminocaproic acid, adipic acid, hexamethylenediamine and 1.6-hexanediol are also provided. | ||||||
| 7 | Methods for biosynthesizing 1,3 butadiene | US13916156 | 2013-06-12 | US09422580B2 | 2016-08-23 | Paul S. Pearlman; Changlin Chen; Adriana Leonara Botes; Alex Van Eck Conradie |
| This document describes biochemical pathways for producing butadiene by forming two vinyl groups in a butadiene synthesis substrate. These pathways described herein rely on enzymes such as mevalonate diphosphate decarboxylase, isoprene synthase, and dehydratases for the final enzymatic step. | ||||||
| 8 | METHODS OF PRODUCING FOUR CARBON MOLECULES | US13524973 | 2012-06-15 | US20130210104A1 | 2013-08-15 | Paul S. Pearlman; Changlin Chen; Adriana L. Botes |
| Disclosed are methods for producing butadiene from one or more of several diverse feedstocks including bioderived feedstocks, renewable feedstocks, petrochemical feedstocks and natural gas. | ||||||
| 9 | METHODS FOR BIOSYNTHESIZING 1,3 BUTADIENE | US15213830 | 2016-07-19 | US20160355844A1 | 2016-12-08 | Paul S. Pearlman; Changlin Chen; Adriana Leonora Botes; Alex Van Eck Conradie |
| This document describes biochemical pathways for producing butadiene by forming two vinyl groups in a butadiene synthesis substrate. These pathways described herein rely on enzymes such as mevalonate diphosphate decarboxylase, isoprene synthase, and dehydratases for the final enzymatic step. | ||||||
| 10 | METHODS FOR BIOSYNTHESIZING 1,3 BUTADIENE | US15211237 | 2016-07-15 | US20160355843A1 | 2016-12-08 | Paul S. Pearlman; Changlin Chen; Adriana Leonora Botes; Alex Van Eck Conradie |
| This document describes biochemical pathways for producing butadiene by forming two vinyl groups in a butadiene synthesis substrate. These pathways described herein rely on enzymes such as mevalonate diphosphate decarboxylase, isoprene synthase, and dehydratases for the final enzymatic step. | ||||||
| 11 | Methods for biosynthesizing 1,3 butadiene | US13691623 | 2012-11-30 | US09422578B2 | 2016-08-23 | Paul S. Pearlman; Changlin Chen; Adriana L. Botes; Alex Van Eck Conradie |
| This document describes biochemical pathways for producing butadiene by forming two vinyl groups in a butadiene synthesis substrate. These pathways described herein rely on enzymes such as mevalonate diphosphate decarboxylase, isoprene synthase, and dehydratases for the final enzymatic step. | ||||||
| 12 | PATHWAYS TO ADIPATE SEMIALDEHYDE AND OTHER ORGANIC PRODUCTS | US14418543 | 2013-09-20 | US20150291987A1 | 2015-10-15 | Man Kit Lau |
| Recombinant microorganisms comprising at least one exogenous nucleic acid sequence and capable of producing adipate semialdehyde are provided. Adipate semialdehyde may be produced in a synthesis pathway utilizing a single thiolase reaction. Adipate semialdehyde may also be produced from intermediates consisting of alpha, omega difunctional aliphatic organic molecules. Methods of using recombinant microorganisms to produce 6-aminocaproic acid, adipic acid, hexamethylenediamine and 1.6-hexanediol are also provided. | ||||||
| 13 | METHODS FOR BIOSYNTHESIZING 1,3 BUTADIENE | US13916156 | 2013-06-12 | US20140141482A1 | 2014-05-22 | Paul S. Pearlman; Changlin Chen; Adriana Leonora Botes; Alex Van Eck Conradie |
| This document describes biochemical pathways for producing butadiene by forming two vinyl groups in a butadiene synthesis substrate. These pathways described herein rely on enzymes such as mevalonate diphosphate decarboxylase, isoprene synthase, and dehydratases for the final enzymatic step. | ||||||
| 14 | PATHWAYS TO ADIPATE SEMIALDEHYDE AND OTHER ORGANIC PRODUCTS | EP13773490.1 | 2013-09-20 | EP2898082A1 | 2015-07-29 | LAU, Man, Kit; MERCOGLIANO, Christopher, P. |
| Recombinant microorganisms comprising at least one exogenous nucleic acid sequence and capable of producing adipate semialdehyde are provided. Adipate semialdehyde may be produced in a synthesis pathway utilizing a single thiolase reaction. Adipate semialdehyde may also be produced from intermediates consisting of alpha, omega difunctional aliphatic organic molecules. Methods of using recombinant microorganisms to produce 6-aminocaproic acid, adipic acid, hexamethylenediamine and 1.6-hexanediol are also provided. | ||||||
| 15 | METHODS OF PRODUCING FOUR CARBON MOLECULES | EP12731825.1 | 2012-06-15 | EP2721164A2 | 2014-04-23 | PEARLMAN, Paul, S.; CHEN, Changlin; BOTES, Adriana, L. |
| Disclosed are methods for producing butadiene from one or more of several diverse feedstocks including bioderived feedstocks, renewable feedstocks, petrochemical feedstocks and natural gas. | ||||||
| 16 | METHODS OF PRODUCING1, 3 - BUTADIENE | PCT/US2012042757 | 2012-06-15 | WO2012174439A3 | 2013-05-23 | PEARLMAN PAUL S; CHEN CHANGLIN; BOTES ADRIANA L |
| Disclosed are methods for producing butadiene from one or more of several diverse feedstocks including bioderived feedstocks, renewable feedstocks, petrochemical feedstocks and natural gas. | ||||||
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