序号 专利名 申请号 申请日 公开(公告)号 公开(公告)日 发明人
21 Phenylacetic acid derivatives, processes and intermediates for their preparation, and compositions comprising them US229972 1999-01-14 US6037378A 2000-03-14 Thomas Grote; Herbert Bayer; Ruth Muller; Hubert Sauter; Reinhard Kirstgen; Volker Harries; Gisela Lorenz; Eberhard Ammermann; Siegfried Strathmann
Phenylacetic acid derivatives of the formula I ##STR1## where the substituents and the index have the following meanings: X is NOCH.sub.3, CHOCH.sub.3, CHCH.sub.3 ;Y is O, NRR.sup.1,R independently of one another are hydrogen and C.sub.1 -C.sub.4 -alkyl;R.sup.2 is cyano, nitro, trifluoromethyl, halogen, alkyl and alkoxy;m is 0, 1 or 2, it being possible for the radicals R.sup.2 to be different when m is 2;R.sup.3 is hydrogen, cyano, C.sub.1 -C.sub.4 -alkyl, C.sub.1 -C.sub.4 -haloalkyl, C.sub.3 -C.sub.6 -cycloalkyl;R.sup.4, R.sup.5 and R.sup.6 have the meanings given in claim 1,and their salts, a process and intermediates for the preparation of these compounds, and compositions comprising them for controlling animal pests and harmful fungi.
22 Process for the preparation of difunctional compounds of high enantiomeric purity US553675 1996-03-04 US5981809A 1999-11-09 Xavier Radisson
A process for preparing a difunctional compound having high enantiomeric purity that is a 1,2-, 1,3-, or 1,4-diol, dithiol, or mercapto alcohol from an optically active starting material that includes an .alpha.-, .beta.-, or .gamma.-hydroxy (or mercapto) aldehyde, ketone, ester, or amide is described. The process is carried out in an anhydrous solvent medium and comprises (1) reducing the starting material with a metal hydride (e.g., sodium borohydride), (2) adding a coreactant that is substituted by at least one, but preferably two, hydroxyl or mercapto groups (e.g., pyrocatechol), and (3) directly distilling the product from the reaction medium. The coreactant preferably has a higher boiling point at normal atmospheric pressure than the difunctional compound. The difunctional compounds are used as reactants for syntheses of agrochemicals or pharmaceuticals, or as precursors for polymers.
23 Phenylacetic acid derivatives, processes and intermediates for use in producing them and agents containing them US51591 1998-04-15 US5948932A 1999-09-07 Thomas Grote; Herbert Bayer; Ruth Muller; Hubert Sauter; Reinhard Kirstgen; Volker Harries; Gisela Lorenz; Eberhard Ammermann; Siegfried Strathmann
Phenylacetic acid derivatives of the formula I ##STR1## where the substituents and the index have the following meanings: x is NOCH.sub.3, CHOCH.sub.3, CHCH.sub.3 ;Y is O, NRR.sup.1,R independently of one another are hydrogen and C.sub.1 -C.sub.4 -alkyl;R.sup.2 is cyano, nitro, trifluoromethyl, halogen, alkyl and alkoxy;m is 0, 1 or 2, it being possible for the radicals R.sup.2 to be different when m is 2;R.sup.3 is hydrogen, cyano, C.sub.1 -C.sub.4 -alkyl, C.sub.1 -C.sub.4 -haloalkyl, C.sub.3 -C.sub.6 -cycloalkyl;R.sup.4, R.sup.5 and R.sup.6 have the meanings given in claim 1,and their salts, a process and intermediates for the preparation of these compounds, and compositions comprising them for controlling animal pests and harmful fungi.
24 Azido containing tetrahydro furan compounds US800671 1997-02-14 US5705658A 1998-01-06 Richard Goschke; Jurgen Klaus Maibaum; Walter Schilling; Stefan Stutz; Pascal Rigollier; Yasuchika Yamaguchi; Nissim Claude Cohen; Peter Herold
.delta.-Amino-.gamma.-hydroxy-.omega.-aryl-alkanoic acid amides of formula I ##STR1## and the salts thereof, have renin-inhibiting properties and can be used as antihypertensive medicinal active ingredients.
25 .delta.-amino-.gamma.-hydroxy-.omega.-aryl-alkanoic acids US674555 1996-07-02 US5654445A 1997-08-05 Richard Goschke; Jurgen Klaus Maibaum; Walter Schilling; Stefan Stutz; Pascal Rigollier; Yasuchika Yamaguchi; Nissim Claude Cohen; Peter Herold
.delta.-Amino-.gamma.-hydroxy-.omega.-aryl-alkanoic acid amides of formula I ##STR1## and the salts thereof, have renin-inhibiting properties and can be used as antihypertensive medicinal active ingredients.
26 .delta.-amino-.gamma.-hydroxy-.omega.-aryl-alkanoic acid amides US687277 1996-07-25 US5646143A 1997-07-08 Richard Goschke; Jurgen Klaus Maibaum; Walter Schilling; Stefan Stutz; Pascal Rigollier; Yasuchika Yamaguchi; Nissim Claude Cohen; Peter Herold
.delta.-Amino-.gamma.-hydroxy-.omega.-aryl-alkanoic acid amides of formula I ##STR1##
27 Leukotriene-B.sub.4 derivatives, process for their production and their use as pharmaceutical agents US244500 1994-05-27 US5502075A 1996-03-26 Werner Skuballa; Bernd Buchmann; Josef Heindl; Wolfgang Fro/ hlich; Roland Ekerdt; Claudia Giesen
Leukotriene-B.sub.4 derivatives of formula I ##STR1## their salts with physiologically compatible bases and their cyclodextrin clathrates are described.
28 Precious metal composition US875412 1992-04-29 US5281635A 1994-01-25 Peter T. Bishop
A homogeneous composition for forming on firing a film of precious metal, which is one or more of platinum, palladium, gold and silver, on a substrate, for instance to decorate table ware, comprises polymeric resin and a solution, in water and a co-solvent, of thiolate of the precious metal, the composition containing 3-22% by weight of the precious metal as the thiolate, and the co-solvent, resin and thiolate being such that as the composition on a substrate dries and is progressively heated in firing, the water evaporates off to leave a homogeneous composition of the resin and thiolate in the co-solvent, then the co-solvent evaporates off to leave a homogeneous composition of the thiolate in the resin, and then the thiolate decomposes to the precious metal while the resin volatilise.
29 PROCESS FOR DEPOLYMERIZING POLYSULFIDES AND THE PREPARATION OF BIS-MERCAPTO-DIETHERS PCT/EP2011/053758 2011-03-14 WO2011113774A1 2011-09-22 VENDERBOSCH, Rudolf, Anthonius, Maria; VERLAAN-HOOFT, Hendrika, Petronella, Maria; TALMA, Auke, Gerardus; KLOBES, Olaf; TATAS, Ralf; VOS, Hendrik, Jan

The invention related to a process for the preparation of a bismercaptodiether by reacting a polysulfide with a monothiol in the presence of a base and to a process for the depolymerization of a polysulfide by reacting said polysulfide with a monothiol in the presence of a base. These processes enable the preparation of bismercaptodiethers without inorganic salt formation.

30 4-((PHENOXYALKYL)THIO)-PHENOXYACETIC ACIDS AND ANALOGS PCT/US2005/033137 2005-09-14 WO2006032023A3 2006-03-23 DEANGELIS, Alan; DEMAREST, Keith, T.; KUO, Gee-Hong; PELTON, Patricia; WANG, Aihua; ZHANG, Rui

The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR modulators to treat or inhibit the progression of, for example, dyslipidemia.

31 PROCESS FOR PRODUCTION OF SULFUR COMPOUNDS PCT/JP2000/008522 2000-12-01 WO01040175A1 2001-06-07
A process for producing a sulfur compound bearing at least one thio group in the molecule by reacting a thiol compound with an organic compound bearing at least one functional group capable of reacting with a mercapto group to thereby form a thio group in the presence of a basic compound, characterized by adjusting the number of moles of water contained in the reaction system to at most 7.5 times the product of the number of moles of the reactant thiol compound and the number of mercapto groups existing in one molecule of the thiol compound.
32 SYNTHESIS OF BENZO[F]QUINOLINONES PCT/US1999/012196 1999-06-01 WO99065878A1 1999-12-23
A process for preparing intermediates and benzoquinolin-3-one pharmaceuticals, such pharmaceuticals are effective in treating conditions consequent on 5 alpha -reductase.
33 PESTICIDAL SUBSTITUTED THIOETHERS PCT/EP2006/000476 2006-01-20 WO2006079480A1 2006-08-03 SCHNATTERER, Stefan; DOELLER, Uwe; MAIER, Michael; PETRY, Friederike; KNAUF, Werner; SEEGER, Karl

The invention relates to the use of thioether derivatives of formula (I) wherein: R1 is an unsubstituted or substituted (C1-C6) alkyl, A is a divalent unit taken from the group CO, CR3(OR4), CR3(O-CO-R4), CR3(COOR4), C(=CR3R4), C(=CR3R4), C(=CR3-COOR4), C(=CR3-CN); X is an unsubstituted or substituted (C1-C3) alkylen, R2 is an unsubstituted or substituted (C1-C10) alkyl, (C3-C7) cycloalkyl, (C3-C7) cycloalkenyl, (C3-C7) cycloalkyl-(C1-C6) alkyl, (C3-C7) cycloalkenyl-(C1-C6) alkyl, (C2-C10) alkenyl, (C2-C10) alkinyl, (C6-C12)-aryl, heteroaryl, heterocyclyl, (C6-C12)-aryl-(C1-C3) alkyl, heteroaryl-(C1-C3) alkyl or heterocyclyl-(C1-C3) alkyl residue and wherein R1 , X and A may form a 3 to 10 membered cycloalkyl ring or a pesticidally acceptable salt thereof, for the control of pests, for controlling pests.

34 4-((PHENOXYALKYL)THIO)-PHENOXYACETIC ACIDS AND ANALOGS PCT/US2005/032938 2005-09-14 WO2006031969A1 2006-03-23 DEANGELIS, Alan; DEMAREST, Keith, T.; KUO, Gee-Hong; PELTON, Patricia; WANG, Aihua; ZHANG, Rui

The invention features 4 ((phenoxyalkyl)thio) phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR modulators to treat or inhibit the progression of, for example, dyslipidemia

35 ACRYLONITRILE COMPOUNDS, PROCESS FOR THEIR PRODUCTION AND PESTICIDES CONTAINING THEM PCT/JP1998/000584 1998-02-13 WO98035935A1 1998-08-20
Novel compounds useful as active ingredients of pesticides are disclosed. Acrylonitrile compounds of formula (I) or their salts, wherein Q is Qa, Qb, Qc or Qd, Y is =C(R4)- or =N-, R1 is alkyl, haloalkyl, etc., each of R2 and R3 is halogen, alkyl which may be substituted, alkenyl which may be substituted, etc., R4 is hydrogen, halogen, alkyl or haloalkyl, l is from 1 to 4, m is from 0 to 5, n is from 0 to 3, q is from 0 to 4, when 1 is 2 or more, a plurality of R2 may be the same or different, when each of m, n and q is 2 or more, a plurality of R3 may be the same or different.
36 NOVEL p-TERPHENYL COMPOUNDS PCT/JP1997002635 1998-02-05 WO98004508A1 1998-02-05
Selective IgE production inhibitors which contain substances inhibiting the production of IgE in the process of the differentiation of matured B cells into antibody-producing cells and the production of the antibody thereby while not or scarcely inhibiting the production of IgG, IgM and/or IgA to be produced simultaneously with IgE; compounds represented by general formula (I); a process for producing the same; and drugs containing the same. In said formula R<1> to R<13> represent each hydrogen, halogeno, lower alkyl, lower alkoxy, etc.; X represents O-, -CH2-, -NR<14>- or -S(O)p-; and Y represents lower alkyl or lower alkenyl.
37 다중 아크릴레이티드에스테르 모노머, 광경화성 조성물 및이들의 제조 방법 KR1020080027504 2008-03-25 KR1020090102211A 2009-09-30 김환기; 이성권; 박상권; 박혜석; 서동완; 임영돈; 최승우
PURPOSE: A multi-acrylated ester monomer, a photo curable material and a process for producing the same are provided to avoid strong toxicity which is harmful to the human body by not using formaldehyde. CONSTITUTION: A polyol or polythiol is represented by chemical formula 1 and is synthesized from cooking oil or vegetable oil. The multiple acrylated estermonomer produces the polyol or polythiol by reacting with methacryloyl chloride or methacryloyl acid. The methacryloyl chloride is represented by chemical formula 2. The methacryloyl acid is represented by chemical formula 3.
38 VCAM-1의 발현을 억제하기 위한 화합물 및 억제방법 KR1020067026799 1998-05-14 KR1020070007207A 2007-01-12 메드포드러셀엠.; 소머즈파트리샤케이.; 홍리케이.; 멩찰스큐.
This invention is in the area of methods and compositions for the inhibition of the expression of VCAM-1 and, in particular, for the treatment of diseases mediated by VCAM-1, including cardiovascular and inflammatory diseases. ® KIPO & WIPO 2007
39 신규 술폰산염 및 그의 유도체, 광산발생제 및 이것을이용한 레지스트 재료 및 패턴 형성 방법 KR1020060030950 2006-04-05 KR1020060107340A 2006-10-13 오사와,유이찌; 와따나베,다께루; 긴쇼,다께시; 고바야시,가쯔히로
본 발명은 하기 화학식 1로 표시되는 술폰산염에 관한 것이다. CF 3 -CH(OCOR)-CF 2 SO 3 - M + 식 중, R은 치환 또는 비치환의 탄소수 1 내지 20의 직쇄상, 분지상 또는 환상의 알킬기, 또는 치환 또는 비치환의 탄소수 6 내지 14의 아릴기를 나타내고, M + 는 리튬 이온, 나트륨 이온, 칼륨 이온, 암모늄 이온 또는 테트라메틸암모늄 이온이다. 본 발명의 술폰산은 분자 내에 에스테르 부위를 갖고 있기 때문에, 부피가 낮은 아실기로부터 부피가 높은 아실기, 벤조일기, 나프토일기, 안트라일기 등의 도입이 용이하여 분자 설계의 폭을 넓힐 수 있다. 술폰산염, 광산발생제, 레지스트 재료
40 신규 술폰산염 및 그의 유도체, 광산발생제 및 이것을이용한 레지스트 재료 및 패턴 형성 방법 KR1020060030950 2006-04-05 KR101038122B1 2011-05-31 오사와,유이찌; 와따나베,다께루; 긴쇼,다께시; 고바야시,가쯔히로
본 발명은 하기 화학식 1로 표시되는 술폰산염에 관한 것이다. CF 3 -CH(OCOR)-CF 2 SO 3 - M + 식 중, R은 치환 또는 비치환의 탄소수 1 내지 20의 직쇄상, 분지상 또는 환상의 알킬기, 또는 치환 또는 비치환의 탄소수 6 내지 14의 아릴기를 나타내고, M + 는 리튬 이온, 나트륨 이온, 칼륨 이온, 암모늄 이온 또는 테트라메틸암모늄 이온이다. 본 발명의 술폰산은 분자 내에 에스테르 부위를 갖고 있기 때문에, 부피가 낮은 아실기로부터 부피가 높은 아실기, 벤조일기, 나프토일기, 안트라일기 등의 도입이 용이하여 분자 설계의 폭을 넓힐 수 있다. 술폰산염, 광산발생제, 레지스트 재료
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