| 序号 | 专利名 | 申请号 | 申请日 | 公开（公告）号 | 公开（公告）日 | 发明人 |
|---|---|---|---|---|---|---|
| 81 | 우레아 경화제를 함유하는 저온 경화성 에폭시 조성물 | KR1020100088834 | 2010-09-10 | KR1020110028242A | 2011-03-17 | 아브도우라자크,아테예하우스세인; 베다지,가미니아난다 |
| PURPOSE: A low temperature curable epoxy composition is provided to afford excellent activation temperature, good reaction heat, and high glass transition. CONSTITUTION: A urea compound is the reaction product of an isocyanate and an alkylated polyalkylenepolyamine having at least one primary or secondary amine and at least two tertiary amines of chemical formula 1, where R1, R2, R3, R4 and R5 independently represent hydrogen, methyl or ethyl; n and m independently are integers from 1 to 6 and; X is an integer from 1 to 10. | ||||||
| 82 | 1-페닐알킬-3-페닐 우레아 유도체 및 그의 제조 방법 | KR1019900011927 | 1990-08-03 | KR1019910004551A | 1991-03-28 | 세끼야데쯔오; 이노우에신야; 효도지아끼; 오꾸시마히로미; 우메즈고헤이; 스즈끼가즈오 |
| 내용 없음. | ||||||
| 83 | 비대칭적으로 치환된 우레아의 제조 방법 | KR1019900011363 | 1990-07-26 | KR1019910002784A | 1991-02-26 | 마틴뮐너; 게르하르트스테른; 마르쿠스뢰슬러 |
| 내용 없음 | ||||||
| 84 | Isocyanate-containing prepolymer and method for making the same | US14380734 | 2013-03-19 | US09505871B2 | 2016-11-29 | Wesley Verbeke; Dimitri Leroy |
| The invention relates to an isocyanate-containing prepolymer obtainable by reacting at least one isocyanate with at least one first compound selected from the group comprising monohydric alcohols, thiols and secondary amines; wherein the ratio of the NCO value of the isocyanate-containing prepolymer, to the OH, SH or NH value, of said monohydric alcohol, thiol or secondary amine respectively ranges from 0.0005 to 1.0000 and wherein said at least one first compound is present in a total amount of at least 40% by weight based on the total weight of the isocyanate-containing prepolymer. | ||||||
| 85 | Colour protection detergent | US14946322 | 2015-11-19 | US09404066B2 | 2016-08-02 | Mareile Job; Birgit Gluesen; John Taylor; Anthony Lawrence |
| The present invention improves dye transfer inhibition in the washing of textiles by the use of urea derivatives comprising sulfonic or carboxylic acid groups. | ||||||
| 86 | USE OF SUBSTITUTED UREAS OR URETHANES FOR IMPROVEMENT OF THE USE PROPERTIES OF MINERAL AND SYNTHETIC NONAQUEOUS INDUSTRIAL FLUIDS | US13783708 | 2013-03-04 | US20160010020A1 | 2016-01-14 | Jan STRITTMATTER; Karl Haeberle; Wolfgang Grabarse; Ivette Garcia Castro; Markus Hansch; Irene Troetsch-Schaller; Stephan Schenk; Michael Schroers; Bernhard Lange |
| The use of substituted diureas, polyureas, bisurethanes or polyurethanes of the formula R1X—CO—NR3R4 in which X is R2N or O and R1 to R4 are each independently hydrogen, alkyl radicals, alkenyl radicals, cycloalkyl radicals, aryl radicals or arylalkyl radicals, where at least one variable must be a radical having at least 4 carbon atoms and where the urea or urethane functionality must be replicated via bridging members, for improvement of the use properties of mineral and synthetic nonaqueous industrial fluids. | ||||||
| 87 | Substituted aromatic compound, hydrogelation agent, hydrogel, and method for gelating aqueous sample | US14003907 | 2012-03-09 | US09115164B2 | 2015-08-25 | Masamichi Yamanaka; Daisuke Higashi |
| According to the present invention, a substituted aromatic compound represented by the following general formula (I) is provided. In general formula (I), A1, A2, and A3 each independently represent an aryl group substituted by a hydrophilic group. | ||||||
| 88 | Crystallized diacetylenic indicator compounds and methods of preparing the compounds | US12261887 | 2008-10-30 | US08269042B2 | 2012-09-18 | Ray H. Baughman; Lee J. Hall; Mikhail Kozlov; Dawn E. Smith; Thaddeus Prusik |
| Crystallized diacetylenic compounds having certain crystallographic and other characteristics; diacetylenic compounds and mixtures crystallized from diacetylenic solutions; methods of preparing and identifying solvent systems for dissolving diacetylenic compounds; diacetylenic solutions; methods of recrystallizing diacetylenic compounds; crystals of 2,4-hexadiyn-1,6-bis(alkylurea) compounds; and ambient condition indicators and time-temperature condition indicators comprising crystallized diacetylenic compounds. | ||||||
| 89 | Histone deacetylase inhibitors and methods of use thereof | US10614498 | 2003-07-07 | US07842835B2 | 2010-11-30 | Alan P. Kozikowski; Anatoly Dritschilo; Mira Jung; Pavel A. Petukhov; Bin Chen |
| The invention provides novel classes of HDAC inhibitors. Methods of sensitizing a cancer cell to the cytotoxic effects of radiotherapy are also provided as well as methods for treating cancer and methods for treating neurological diseases. Additionally, the invention further provides pharmaceutical compositions comprising an HDAC inhibitor of the invention, and kits comprising a container containing an HDAC inhibitor of the invention. | ||||||
| 90 | PARTIALLY FLUORINATED UREAS AND AMIDES | US11837653 | 2007-08-13 | US20090047435A1 | 2009-02-19 | Keith Ward Hutchenson; Anilkumar Raghavanpillai; Stefan Reinartz |
| One aspect of the invention is a compound of formula (I) Ro-[L-(CqH2qS)pCrH2rRf]2 (I) wherein Ro is a divalent organic group having 2 to 40 carbon atoms; L is a linking group selected from —NHC(O)NH— or —C(O)NH— wherein the left side of the linking group is bonded to Ro; p is an integer of 0 or 1; q is an integer of 2 to 10; r is an integer of 1 to 10; and Rf is a linear or branched C1-C6 perfluoroalkyl group.Another aspect of the invention is a composite material comprising a porous support and a porous nanoweb, wherein said porous nanoweb comprises fibrous structures of between about 10 nm and about 1000 nm effective average fiber diameter as determined with electron microscopy; said fibrous structures being comprised of one or more compositions of formula (I).Another aspect of the invention is a method for making a composite material comprising a porous support and a porous nanoweb. | ||||||
| 91 | Tetralin and indane derivatives and uses thereof | US11985459 | 2007-11-15 | US20080293751A1 | 2008-11-27 | Robert Greenhouse; Ralph New Harris, III; Saul Jaime-Figueroa; James M. Kress; David Bruce Repke; Russell Stephen Stabler |
| Compounds of the formula I: or pharmaceutically acceptable salts thereof, wherein m, p, q, Ar, R1 and R2 are as defined herein. Also provided are methods for preparing, compositions comprising, and methods for using compounds of formula I. | ||||||
| 92 | Histone Deacetylase Inhibitors | US11629447 | 2005-07-08 | US20080033015A1 | 2008-02-07 | Sandro Belvedere; Christopher Hamblett; Thomas Miller; David Witter; Jiaming Yan |
| This invention relates to hydroxamic acid derivatives having a urea linkage, that are inhibitors of histone deacetylase (HDAC), and are useful in the prevention and/or treatment of cellular proliferative diseases, for example cancer, autoimmune, allergic and inflammatory diseases, diseases of the central nervous system (CNS) such as neurodegenerative diseases, and in the prevention and/or treatment of restenosis. | ||||||
| 93 | Process for the preparation of arylalkynyl-N-hydroxyurea derivatives having lipoxygenase inhibitory activity | US698674 | 1996-08-16 | US5714633A | 1998-02-03 | Sanjay R. Chemburkar; Hemantkumar H. Patel; David P. Sawick; Albert V. Thomas |
| The present invention provides a process for the preparation of a compound of formula ##STR1## wherein R is a straight or branched alkyl group of from one to twelve carbon atoms; M represents hydrogen or a pharmaceutically acceptable cation; and A is selected from optionally substituted carbocyclic phenyl. | ||||||
| 94 | Glycolic acid derivatives | US670677 | 1991-03-18 | US5147857A | 1992-09-15 | Peter Raddatz; Claus J. Schmitges; Klaus-Otto Minck |
| New glycolic acid derivatives of the formula IX--O--CR.sup.1 R.sup.2 --CO--Y--NR.sup.3 --CHR.sup.4 --CR.sup.5 --CH.sub.2 --CR.sup.6 R.sup.7 --Z Iin which R.sup.1 to R.sup.7, X, Y and Z have the meanings indicated herein, and salts thereof, inhibit the activity of human plasma renin. | ||||||
| 95 | N, N-disubstituted oligourethanes and polyurethanes, a process for their preparation, and their use in the production of plastics | US501212 | 1990-03-29 | US5099058A | 1992-03-24 | Josef Sanders; Dieter Dieterich |
| The present invention relates to N,N-disubstituted compounds containing urethane groups and terminal hydroxyl groups corresponding to the general formula ##STR1## wherein X is the residue of a strong memobasic or polybasic acid remaining after dissociation of the proton or protons of said acid or a hydroxyl group;Y is an n-functional hydrocarbon group having a molecular weight of from about 15 to about 8000 (preferably from about 300 to about 4000) and optionally interrupted by oxygen, sulfur, or silicon atoms, or by ester, carbonate, urea, N-monosubstituted urethane, or N,N-disubstituted urethane groups;1.sub.R hydrogen or a hydrocarbon group having a molecular weight of from about 15 to about 200;2.sub.R is the radical of an alkylating or arylating agent; and is an integer of from 2 to about 6.The present invention further relates to a process for preparing such compounds and to a method for using such compounds in the production of plastics. | ||||||
| 96 | Alkene, alkyne or cycloalkylene derivatives | US337862 | 1989-04-14 | US5084478A | 1992-01-28 | Leslie R. Hughes; Howard Tucker |
| A compound of the formula ##STR1## wherein X has the formula --CR.sup.5 .dbd.CR.sup.6 --, --C.tbd.C-- or ##STR2## wherein ring A is phenyl, naphthyl or heterocyclic; wherein R.sup.1 is hydrogen, alkyl, alkanoyl or aroyl;wherein R.sup.2, R.sup.3 and R.sup.4, which may be the same or different, each is an electron withdrawing substituent or each is hydrogen or alkyl, alkoxy or dialkylamino, provided that when ring A is phenyl or naphthyl at least one of R.sup.2, R.sup.3 and R.sup.4 is an electron-withdrawing substituent;wherein R.sup.5 and R.sup.6, each is hydrogen, halogeno or alkylwherein R.sup.7 is alkyl or halogenoalkyl; and wherein R.sup.8 has the formula --Y--Q--R.sup.9 wherein Y is straight- or branched-chain alkylene or alkenylene; wherein Q is --O--, --S--, --SO-- or --SO.sub.2 --;and wherein R.sup.9 is alkyl of up to 6 carbon atoms which contains one or more defined substituents, processes for their manufacture and pharmaceutical compositions containing them. The compounds possess antiandrogenic activity and may be used in the treatment of androgen-dependent disease conditions such as prostatic disease, acne, hirsutism or seborrhoea. | ||||||
| 97 | Method of preparation of optically active .alpha.-amino-acids | US486307 | 1990-02-28 | US5026906A | 1991-06-25 | Sandro Di Gioacchino; Antonio Paolinelli; Luciano Re |
| A new process of synthesis of optically active .alpha.-amino acids is described through nitrosation in a non-aqueous, aprotic system of the corresponding N-carbamyl derivatives followed by decomposition of the thus obtained N-nitroso derivatives in aqueous acidic medium. The process, which is of a general applicability, leads to a remarkable increase in the reaction yields, due to the suppression of the main side reaction leading to the corresponding .alpha.-hydroxy-acid. Some N-nitroso intermediates, which can be recovered from the process of the invention, are also described. | ||||||
| 98 | Selected difluoro derivatives | US58079 | 1987-06-04 | US4880780A | 1989-11-14 | Diane A. Trainor; Mark M. Stein |
| The invention discloses a series of difluoroketone, mono- di- and tri-peptide derivatives of formula Ia, Ib and Ic:______________________________________ (Formula set out on pages following Examples) Ia (Formula set out on pages following Examples) Ib (Formula set out on pages following Examples) Ic ______________________________________ and salts thereof where appropriate, and wherein the radicals are defined hereafter in the specification. The derivatives are useful in inhibiting the action of human leukocyte elastase. There are also disclosed methods and intermediates for the manufacture of, and pharmaceutical compositions comprising, the said derivatives. | ||||||
| 99 | Alkene, alkyne or cycloalkylene derivatives | US830136 | 1986-02-18 | US4845119A | 1989-07-04 | Leslie R. Hughes; Howard Tucker |
| A compound of the formula ##STR1## wherein X has the formula --CR.sup.5 .dbd.CR.sup.6 --, --C.tbd.C-- or ##STR2## wherein ring A is phenyl, naphthyl or heterocyclic; wherein R.sup.1 is hydrogen, alkyl, alkanoyl or aroyl;wherein R.sup.2, R.sup.3 and R.sup.4, which may be the same or different, each is an electron withdrawing substituent of each is hydrogen or alkyl, alkoxy or dialkylamino, provided that when ring A is phenyl or naphthyl at least one of R.sup.2, R.sup.3 and R.sup.4 is an electron-withdrawing substitutent;wherein R.sup.5 and R.sup.6, each is hydrogen, halogeno or alkyl;wherein R.sup.7 is alkyl or halogenoalkyl; and wherein R.sup.8 has the formula --Y--Q--R.sup.9 wherein Y is straight- or branched-chain alkylene or alkenylene; wherein Q is --O--, --S--, --SO-- or --SO.sub.2 --; andwherein R.sup.9 is alkyl or up to 6 carbon atoms which contains one or more defined substituents, processes for their manufacture and pharmaceutical compositions containing them. The compounds possess antiandrogenic activity and may be used in the treatment of androgen-dependent disease conditions such as prostatic disease, acne, hirsutism or seborrhoea. | ||||||
| 100 | (Meth)-acrylic acid esters and the use thereof | US870610 | 1986-06-04 | US4744828A | 1988-05-17 | Jens Winkel; Bruno Bomer; Carlhans Suling; Jurgen Reiners; Wolfgang Podszun |
| The invention relates to novel (meth)-acrylic acid derivatives of tricyclodecanes of the formula ##STR1## in which R.sup.1 and R.sup.2 are identical or different and denote hydrogen, lower alkyl, lower alkoxy, halogen or trifluoromethyl and R.sup.3 and R.sup.4 are identical or different and represent the groups. ##STR2## in which X is a divalent bridge member comprising the group ##STR3## and Y is a linear or branched hydrocarbon chain which has 2 to 10 carbon atoms and can optionally contain oxygen bridges and is optionally substituted by 1 to 4 acrylate or methacrylate radicals, andR.sup.5 represent hydrogen or methyl andR.sup.6 represents hydrogen, lower alkyl or phenyland to their use in dental compositions. | ||||||
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