子分类：
| 序号 | 专利名 | 申请号 | 申请日 | 公开（公告）号 | 公开（公告）日 | 发明人 |
|---|---|---|---|---|---|---|
| 61 | Phenoxyalkyl amines and agricultural and horticultural fungicide | JP30323889 | 1989-11-24 | JPH075442B2 | 1995-01-25 | 智子 伊丸岡; 茂生 吉中; 和俊 吉川; 晃規 小田; 昭宣 田中 |
| 62 | Pesticides containing the substitution of 2,4-diamino-5-cyano-pyrimidine and the compound | JP10794787 | 1987-04-30 | JPH0688981B2 | 1994-11-09 | クリスチャンセン オッド; クリスチンソン ハウクール |
| 63 | Preparation of ortho-amide | JP21665192 | 1992-07-23 | JPH05194333A | 1993-08-03 | HAINTSUUURURIHI BURANKU; HERUMUUTO KURAUSU; GERUHARUTO MARUTSUORUFU; NIKORAUSU MIYURAA |
| PURPOSE: To industrially advantageously obtain ortho-amides by the reaction of alkoxymethylene iminium salts or formamidinium salts with alcoholates having a highly activated state. CONSTITUTION: Salts expressed by formula I are allowed to react with alcoholates expressed by M 1OR 1 (M 1 is alkali metal or alkaline earth metal; R 1 is alkyl, alkenyl, alkoxyalkyl, alkoxyalkenyl, cycloalkyl, alkylene-OM 1 or aralkyl) of a highly activated state to obtain ortho-amides expressed by formula II. In formula I, R 2, R 3 are each alkyl, alkenyl, alkoxyalkyl, alkoxyalkenyl, cycloalkyl, aryl, aralkyl, a 5 to 7-member satd. or unsatd. heteroring having one or two heteroatoms (N, O, S); R 4 is OR 5, NR 5R 6 (R 5, R 6 are each R 2 or R 3); X - is alkylsulfate anion, arylsulfonic acid anion, chloride anion, hexafluorophosphoric acid anion, etc. COPYRIGHT: (C)1993,JPO | ||||||
| 64 | Arylalkyl-amine and-amide having anticonvulsive action and nerve protecting action | JP20706289 | 1989-08-11 | JPH02131452A | 1990-05-21 | GRIFFITH RONALD CONRAD; NAPIER JAMES JOSEPH |
| PURPOSE: To use partially novel specific arylalkyl-amine and -amide in the prevention and treatment of nerve disorders as a medicine having anticonvulsive, sedative and nerve protecting actions and low in toxity and having various excellent pharmacological properties. CONSTITUTION: A partially novel compd. represented by the formula [wherein Ar 1 and Ar 2 are each phenyl having one or more substituent (e.g. NH 2, NO 2, a halogen) and one of them may be phenyl; R 1 and R 3 are each H or a 1-6C alkyl; R 2 is H or COCH 2NH 2; and, when R 2 is H, Ar 1 and Ar 2 may be phenyl, a fluorophenyl, etc., and R 1 may be a 1-6C alkoxycarbonyl etc. When R 2 is H in a novel substance, R 1 is a 1-6C alkyl] or its pharmacologically acceptible salt is used as a medicine, especially, an anti-epilepsy agent, an anti-anoxia agent or an N-methyl-(d)-asparate blocking agent. The above compd. has excellent pharmacological properties low in toxity as compared with a similar compd. and acting long and having a wide acting range and strong action and low in side effect. COPYRIGHT: (C)1990,JPO | ||||||
| 65 | 2,4-diamino-1,3,5-trimethoxybenzene, manufacture and hair dye composition | JP15659888 | 1988-06-24 | JPS6485908A | 1989-03-30 | ARETSUKUSU YUNINO; JIYAN JIYATSUKU BANDENBOTSUSHI; HERUBE BOROUIAKU; JIERAARU RANGU |
| NEW MATERIAL: 2,4-Diamino 1,3,5-trimethoxybenzene represented by the formula and its acid addition salt. USE: An oxidation dye precursor for dyeing a keratin fiber, especially hair, above all, a coupler advantageously usable in combination with a para type oxidation dye precursor in an aqueous medium permissible as a cosmetic. PREPARATION: 2,5-Dnitro-1,3,5-trimethoxybenzene is catalytically reduced in water, a lower alcohol, a glycol and/or a glycol ether, as necessary, in the presence of a catalyst such as palladium or nickel deposited on a support such as carbon, calcium carbonate, barium carbonate, alumina or silica gel at 50-200 deg.C temperature under a hydrogen pressure to afford the compound represented by the formula. The compound is capable of satisfying all of desired requirements (stability of dyed hair to rays of light, washing, unfavorable weather and perspiration or nontoxicity, etc.) as the coupler. | ||||||
| 66 | Substituted 2, 4-diamino-5-cyanopyrimidine and insect and mite control method using the same | JP10794787 | 1987-04-30 | JPS62263162A | 1987-11-16 | HAUKUURU KURISUCHINSON; OTSUDO KURISUCHIYANSEN |
| 67 | 황화수소의 고온 선택적 흡수를 위한 방법 | KR1020147036342 | 2013-05-29 | KR1020150044857A | 2015-04-27 | 크리치필드제임스에드워드; 저우징준 |
| 감소된황화수소농도를가지는처리된가스스트림을수득하기위해서황화수소와이산화탄소양자의농도를가지는가스스트림을처리하기위한고온선택적흡수프로세스에관한것이다. 고온선택적흡수프로세스는, 어려운흡수조건하에가스스트림의프로세싱을가능하게하고본 발명의흡수프로세스의다른특징들을제공하는신규한흡수성조성물을독특하게이용한다. | ||||||
| 68 | 6-(4-페닐부톡시)헥실아민의 신규한 유도체 및 살메테롤의제조방법 | KR1020017003977 | 1999-09-20 | KR1020010079948A | 2001-08-22 | 베싸벨문트호르디; 달마세스바르호안페레; 마르키야스올론드리스프란시스코 |
| 본 발명은 화학식 I의 6-(4-페닐부톡시)헥실아민의 신규한 유도체 및 이의 제조방법에 관한 것이다. 화학식 I 상기식에서, R 1 은 CHO 또는 CHOR 3 OR 4 [여기서, R 3 및 R 4 는 독립적으로 C 1 -C 6 알킬 또는 아르알킬이거나 R 3 과 R 4 는 5원 또는 6원 환형 아세탈을 형성한다]이고, R 2 는 H, 벤질 그룹, 알킬옥시카보닐 그룹, 아릴옥시카보닐 그룹, 아르알킬옥시카보닐 그룹 또는 아실 그룹이다. 본 발명은 또한, 화학식 13의 유기금속성 화합물을 저온에서 불활성 용매중에서 R 1 이 CHO이고 R 2 가 알킬옥시카보닐 그룹, 아릴옥시카보닐 그룹, 아르알킬옥시카보닐 그룹 또는 아실 그룹인 화학식 I의 합성 중간체와 반응시킴을 특징으로 하는, 살메테롤 또는 약제학적으로 허용되는 이의 염의 신규한 제조방법에 관한 것이다. | ||||||
| 69 | 레시니페라톡신 약리기를 함유하여 강력한 바닐로이드수용체의 효현제 및 진통제로서 사용하는 바닐로이드동족체 및 이를 함유하는 약학적 조성물 | KR1020000008164 | 2000-02-21 | KR1020010014495A | 2001-02-26 | 이지우; 오우택; 박영호; 서영거; 박형근; 김희두 |
| PURPOSE: Provided is a vanilloid analogue which contains resiniferatoxin pharmacophores so as to be useful as a potent vanilloid receptor agonists and analgesics. Also, a pharmaceutical composition is provided which contains an effective amount of the same, as an active ingredient and a pharmaceutically acceptable carrier, and which is used for treating bladder hypersensitivity. CONSTITUTION: A vanilloid analogue is represented by the formula (1) wherein, X is an oxygen atom or a sulfur atom; A is -NHCH2- or -CH2; R1 is a substituted or unsubstituted alkylaryl group having 1-4 carbons, or R4CO-(in which, R4 is an alkyl group having 1-18 carbons, an alkenyl group having 2-18 carbons, or a substituted or unsubstituted aryl group having 6-10 carbons); R2 is a hydrogen atom, an alkyl group having 1-6 carbons, an alkoxy group having 1-6 carbons, a haloalkyl group having 1-6 carbons or a halogen atom; R3 is a hydrogen atom, an alkyl group having 1-4 carbons, an amino alkyl group, a diacid monoester group, or an alpha-alkylacid group; and * represents a chiral carbon atom. | ||||||
| 70 | (+)1-(3,4,5-트리메톡시)벤질옥시메틸-1-페닐-N,N-디메틸-N-프로필아민, 이의제조방법 및 치료학적용도 | KR1019890008856 | 1989-06-27 | KR100146340B1 | 1998-08-17 | 질베르구스따브오바르드; 알랭삐에르깔브뜨; 아그네스그로우헬; 헹리쟈꼬벨리; 쟝-루이스주니에; 자비에르버나아드루이스빠스꼬드; 프랑소와죠셉로앙 |
| 내용없음 | ||||||
| 71 | 3-아릴옥시-3-치환된프로판아민,이의제조방법 및이를함유하는 약제학적조성물 | KR1019870014449 | 1987-12-18 | KR1019960003808B1 | 1996-03-22 | 데이비드웨인로버트슨; 데이비드타이웨이웡; 요셉헤르만크루쉰스키 |
| 내용 없음. | ||||||
| 72 | 방향족 디아민화합물 및 그 제조방법 | KR1019900016962 | 1990-10-23 | KR1019940007740B1 | 1994-08-24 | 야마구찌게이자브로오; 우라가미다쯔히로; 다나베요시미쯔; 야마자기미도리; 다마이쇼오지; 야마야노리마사; 오오다마사히로; 야마구찌아끼히로 |
| 내용 없음. | ||||||
| 73 | Dispersants | US13984711 | 2012-02-06 | US09580616B2 | 2017-02-28 | Dario Fornara; Alan Nappa; Tamara Verzotti; Paolo Prampolini; Stefano Crespi; Giovanni Floridi; Giuseppe Li Bassi |
| Compound of Formula (1); wherein: Zw is an organic radical comprising w amino groups, in which w is a number and 5≦w≦3,000; A and B are independently oxy-C1-C20-alkylene carbonyl groups or oxy-C2-C20-alkenylene carbonyl groups derived from hydroxy carboxylic acids or lactones; T is hydrogen or R—CO—, where R is a C1-C50 hydrocarbyl group; Y is a C3-C4-alkylene radical linked to an amino group of Zw; Y′ is an ionic salt link between an amino group of Zw and the terminal carbonyl of (A)r-(B)p-T; r and p are independently numbers between 0 and 50 and r+p>2; s, m and v are numbers; 0.99w≦s+m≦2w; and 0.3w≦s+v≦2w are suitable as dispersants and milling aids. | ||||||
| 74 | Curing agent for low temperature cure applications | US14265731 | 2014-04-30 | US09334409B2 | 2016-05-10 | Frederick Herbert Walker; Michael Ian Cook; Gamini Ananda Vedage; Robert Marjo Theodoor Rasing |
| The present invention provides Mannich base derivatives of N,N′-dimethyl secondary diamine polymers including Mannich base derivatives of methylamine-terminated poly-(N-methylazetidine) and Mannich base derivatives of methylamine-terminated poly-(N-methylazacycloheptane). Amine curing agent compositions and amine-epoxy compositions containing Mannich base derivatives of N,N′-dimethyl secondary diamine polymers are also disclosed. | ||||||
| 75 | Methods of synthesizing 2-substituted-1,4-benzenediamine | US14085617 | 2013-11-20 | US09216945B2 | 2015-12-22 | John Michael Gardlik; Garry Steven Garrett; Bryan Patrick Murphy; Guiru Zhang; Robert Edward Shumate; James S. Anderson |
| Disclosed is a method of making a 2-substituted-1,4-benzenediamine by nucleophilic aromatic substitution. | ||||||
| 76 | Process for the production of choline hydroxide | US14369014 | 2011-12-29 | US09216944B2 | 2015-12-22 | Kristof Moonen; Dieter Ulrichts; Daan Scheldeman |
| A continuous process for the production of choline hydroxide includes reacting ethylene oxide, trimethylamine, and water in a reaction zone to form a reaction mixture and extracting heat from the reaction mixture. Subsequently, phase separation of the reaction mixture is induced to obtain a choline hydroxide phase and an organic liquid phase comprising trimethylamine. A choline hydroxide solution (e.g., at a concentration of about 40% to 50% by weight, based on total weight of the choline hydroxide solution) is obtained from the choline hydroxide phase. | ||||||
| 77 | Compositions and methods for labeling and imaging phospholipids | US13147453 | 2010-02-04 | US08987514B2 | 2015-03-24 | Adrian Salic |
| The present invention provides a method to label phospholipids in vivo based on the metabolic incorporation of an alkynyl- or azido-labeled metabolic precursor into phospholipids. The resulting phospholipids have alkynyl or azido moieties, which, upon reaction with a labeled azide or alkyne, respectively, form labeled compounds that can be visualized using optical or electron microscopy with high sensitivity and spatial resolution in cells or tissue. The present method provides a valuable tool for imaging phospholipid synthesis, turnover and subcellular localization in cultured cells as well as in animals. | ||||||
| 78 | Process for preparing alkylalkanolamines | US13379187 | 2010-06-25 | US08916728B2 | 2014-12-23 | Christophe Ruppin; François Guillemet |
| The present invention relates to a process for preparing alkylalkanolamines, comprising the reaction of a carbonyl-based compound with a hydroxylalkylamine, in the presence of hydrogen and a catalyst. | ||||||
| 79 | Compositions and methods of use of electron transport system inhibitors | US12281364 | 2007-03-02 | US08884061B2 | 2014-11-11 | Michio Kurosu; Dean Calvin Crick |
| The invention provides compounds of the formula: or a pharmaceutically acceptable salt thereof, where m, n, R1, R2, R3 R4, R5, R6, R7 are those defined herein. The invention also provides pharmaceutical compositions comprising a compound of the invention, methods for using compounds and/or pharmaceutical compositions of the invention, and methods for synthesizing compounds of the invention. | ||||||
| 80 | Aryloxy amine compounds and their use as sodium channel modulators | US12741124 | 2008-10-31 | US08716528B2 | 2014-05-06 | Bevyn Jarrott |
| The present invention relates generally to the field of therapeutic treatment and compounds having utility therefor, in particular the therapy or management of conditions associated with excessive, unwanted or undesirable sodium ion passage through cellular membranes via voltage-gated sodium channels. In one embodiment the invention is concerned with the treatment of neuropathic pain. The invention contemplates to aryloxy-substituted amines, as sodium channel blockers or modulators. In further embodiments, the invention also relates to compounds which may advantageously have dual sodium channel blocker/modulating and antioxidative (free-radical scavenging) effects. Methods for their manufacture and compositions containing the compounds are also contemplated. | ||||||
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