| 序号 | 专利名 | 申请号 | 申请日 | 公开（公告）号 | 公开（公告）日 | 发明人 |
|---|---|---|---|---|---|---|
| 41 | Squaric acid derivative, squarate dye and their preparation | JP11261992 | 1992-05-01 | JPH05148258A | 1993-06-15 | DONARUDO EI MATSUKUGOWAN; POURINA PII GARUSHIA; JIYON DABURIYU RII; TOOMASU KEI SUPENSAA; SUCHIIBUN JIEI TERUFUAA; MAIKURU JIEI ZURAU |
| PURPOSE: To obtain a new squaric acid deriv. useful as an intermediate of a squarate dye, etc. CONSTITUTION: The squaric acid deriv. is a compd. of the formula (where Q 1 is a heterocyclic nucleus; R 1 is H or an aliphatic group; and A and B are Cl or Br), e.g. 3[2,6-di(1,1dimethylethyl)(4H-pyran-4ylidene)methyl]2,4,4- trichlorocyclobut2-ene1-one. The compd. of the formula is obtd., e.g. by condensing a 2,3,4,4tetrahalocyclobut2-ene-1one with a compd. of the formula Q 1CH 2R 1 in the presence of a base. COPYRIGHT: (C)1993,JPO | ||||||
| 42 | JPH0327903B2 - | JP13412284 | 1984-06-30 | JPH0327903B2 | 1991-04-17 | KATAGIRI KAZUHARU; OGUCHI YOSHIHIRO; OOTAKE TAKESHI; ARAO KOZO; TAKASU YOSHIO |
| 43 | JPH0327900B2 - | JP13411884 | 1984-06-30 | JPH0327900B2 | 1991-04-17 | KATAGIRI KAZUHARU; OGUCHI YOSHIHIRO; OOTAKE TAKESHI; ARAO KOZO; TAKASU YOSHIO |
| 44 | Photoconductive film and electrophotographic sensitive body using it | JP12012884 | 1984-06-12 | JPS60263158A | 1985-12-26 | KATAGIRI KAZUHARU; OGUCHI YOSHIHIRO; OOTAKE TAKESHI; ARAO KOUZOU; TAKASU YOSHIO |
| PURPOSE:To obtain an electrophotographic sensitive body having characteristics high in sensitivity to light in a long wavelength region by forming a photosensitive layer having an azulenium salt compd. represented by a specified formula on a conductive substrate. CONSTITUTION:The azulenium salt compd. is represented by general formula I, II, or III in which R1-R5 are each H, halogen, or a univalent org. residue; X is an atomic group necessary to form an optionally substd. 5-, 6-, or 7-membered aromatic ring; A is a bivalent org. group combined through a double bond; and Z<-> is an anion residue. Said compd. is vapor deposited or dissolved or dispersed in a proper binder and a photoconductive film contg. it is formed to obtain an electrophotographic sensitive body. | ||||||
| 45 | Manufacture of pyrylium salts | JP10253683 | 1983-06-08 | JPS5910578A | 1984-01-20 | ARIBERO JIERAARU RAJIYOARISON; KURISUCHIYAN MOORISU RUUSERU |
| 46 | Manufacture of daunosamine hydrochloride and intermediate therefor and manufacture intermediate therefor and manufacture | JP3137681 | 1981-03-06 | JPS56139476A | 1981-10-30 | ROI RESUTAA UISURAA |
| 47 | SMALL MOLECULE LIPID II INHIBITORS | EP16879970.8 | 2016-12-20 | EP3393473A1 | 2018-10-31 | DE LEEUW, Erik; MACKERELL, Alexander; FLETCHER, Steven; CHAUHAN, Jamal |
| Newly synthesized derivatives of BAS00127538 have been discovered to possess antibiotic activity and to combat resistant bacterial strains. Compounds and pharmaceutical compositions containing these compounds are described, and are based on a generic scaffold structure. Synthetic methods and methods of using the compounds also are described. Preferred compound 6jc48-1 ((E)-2,4-bis(4-bromophenyl)-6-(4- (dimethylamino)styryl)pyrylium boron tetrafluoride salt) binds to Lipid II with high affinity, has markedly reduced cytotoxicity than BAS00127538, and retains activity against drug-resistant strains of Enterococci. It is stable in plasma, has dramatically improved pharmacokinetic and pharmacodynamics properties, and possesses in vivo efficacy in a mouse model of sepsis. | ||||||
| 48 | Phenylglycine derivatives as serine protease inhibitors | EP04077367.3 | 2001-06-12 | EP1510515A1 | 2005-03-02 | Liebeschuetz, John Walter Laburnum Cottage; Murray, Christopher William; Young, Stephen Clinton; Camp, Nicholas Paul; Jones, Stuart Donald; Wylie, William Alexander; Masters, John Joseph; Wiley, Michael Robert; Sheehan, Scott Martin; Engel, David Birenbaum; Watson, Brian Morgan; Guzzo, Peter Robert; Mayer, Michael John |
A process for the preparation of compounds of formula (I)
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| 49 | Novel pyrylium compound, process for making the same, nucleic acid stain, and labeled nucleic acid | EP00115763.5 | 2000-07-21 | EP1070709B1 | 2004-12-01 | Suzuki, Tomohiro; Okamoto, Tadashi; Yamamoto, Nobuko |
| 50 | Light-emitting material for organo-electroluminescence device and organic electroluminescence device | EP98301986.0 | 1998-03-17 | EP0866110B1 | 2004-10-20 | Onikubo, Toshikazu; Tamano, Michiko; Okutsu, Satoshi; Enokida, Toshio |
| 51 | A method for detecting a target substance in a sample, utilizing pyrylium compound | EP95303567.2 | 1995-05-25 | EP0684239B1 | 2003-12-10 | Yamamoto, Nobuko, c/o Canon K.K.; Okamoto, Tadashi, c/o Canon K.K. |
| 52 | Process for detecting target nucleic acid, process for quantifying the same, and pyrylium compound for chemiluminescence analysis | EP97307682.1 | 1997-09-30 | EP0837141B1 | 2003-01-08 | Okamoto, Tadashi; Yamamoto, Nobuko |
| 53 | PHOSPHABENZOLVERBINDUNGEN UND IHRE VERWENDUNG ALS LIGANDEN FÜR HYDROFORMYLIERUNGSKATALYSATOREN | EP00910839.0 | 2000-03-15 | EP1161437A1 | 2001-12-12 | PACIELLO, Rocco; MACKEWITZ, Thomas; RÖPER, Michael; BREIT, Bernhard |
| The invention relates to phosphabenzene compounds of general formula (I), wherein the radicals R?1 to R13¿, independently of each other, are hydrogen, COOM, SO¿3?M, NR3X, NR2, OR, COOR or SR (with M = hydrogen, NH4 or alkali metal, X = anion, R = hydrogen or C1-6-alkyl), or C1-12-alkyl, C6-12-aryl, C7-12-aralkyl, C7-12-alkaryl or C3-6-heteroaromatics. The alkyl, aryl, alkaryl and aralkyl radicals can be substituted with the aforementioned radicals and two or more of the radicals can be linked to form aliphatic or annellated rings, at least one of the radicals R?4 and R8¿ and at least one of the radicals R?9 and R13¿ being different from hydrogen. The inventive compounds can be used for producing hydroformylation catalysts. | ||||||
| 54 | Light-emitting material for organo-electroluminescence device and organic electroluminescence device | EP98301986.0 | 1998-03-17 | EP0866110A1 | 1998-09-23 | Onikubo, Toshikazu; Tamano, Michiko; Okutsu, Satoshi; Enokida, Toshio |
A light-emitting material which serves to emit light having a high brightness and is almost free of deterioration in light emission, and an organic EL device for which the light-emitting material is adapted, the material having the formula (1)
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| 55 | Process for detecting target nucleic acid, process for quantifying the same, and pyrylium compound for chemiluminescence analysis | EP97307682.1 | 1997-09-30 | EP0837141A2 | 1998-04-22 | Okamoto, Tadashi; Yamamoto, Nobuko |
The present invention provides a process for detecting or quantifying a target nucleic acid in a sample, the process comprising the steps of associating a chemiluminescent compound, capable of being associated with a double-stranded nucleic acid, with a double-stranded nucleic acid including the target nucleic acid, and detecting or measuring chemiluminescence derived from the chemiluminescent compound associated with the double-stranded nucleic acid. According to the process, the target nucleic acid in the sample can be highly sensitively detected, or precisely quantified. |
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| 56 | Synthesis of squarylium compounds | EP92107574 | 1992-05-05 | EP0516985B1 | 1997-12-29 | MCGOWAN DONALD A; SPENCER THOMAS K; GARCIA PAULINA P; TELFER STEPHEN J; LEE JOHN W; ZURAW MICHAEL J |
| 57 | NOVEL FRUORESCENT COMPOUNDS AND BIOLOGICAL DIAGNOSTIC DEVICES | EP86903061.9 | 1986-04-23 | EP0220284B1 | 1990-01-31 | ARNOST, Michael, J.; INBAR, Shai; MENEGHINI, Frank, A.; PALUMBO, Paul, S.; STROUD, Stephen, G.; ZEPP, Charles, M. |
| Novel fluorescent compounds which are conjugates of a biologically active moiety and an arylidene dye moiety. The compounds have a large Stokes shift and are useful in applications such as biological diagnostic elements. | ||||||
| 58 | NOVEL FRUORESCENT COMPOUNDS AND BIOLOGICAL DIAGNOSTIC DEVICES | EP86903061.0 | 1986-04-23 | EP0220284A1 | 1987-05-06 | ARNOST, Michael, J.; INBAR, Shai; MENEGHINI, Frank, A.; PALUMBO, Paul, S.; STROUD, Stephen, G.; ZEPP, Charles, M. |
| Nouveaux composés fluorescents qui sont des conjugués d'une moitié biologiquement active et d'une moitié de colorant à base d'arylidène. Les composés présentent un décalage de Stokes important et sont utiles en tant qu'éléments diagnostiques biologiques. | ||||||
| 59 | Procédé de préparation de sels de pyrylium | EP78420014.9 | 1978-11-14 | EP0002164A1 | 1979-05-30 | Arnaud, Michel; Roussel, Christian |
Procédé de préparation d'un sel de polyalcoyl pyrylium comportant au moins 3 restes alcoyles en position 2, 4, 6, par réaction d'un alcane ramifié comportant au moins un atome de carbone tertiaire avec un halogénure d'al- canoyle ou un anhydride alcanoïque et un halogénure d'alcoyle, en présence d'un acide de Lewis, selon le schéma probable.
Les sels de pyrylium peuvent être utilisés pour préparer des alcoylpyridines et des dialcoylphénols. |
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| 60 | Polymers And Oligomers With Aggregation-Induced Emission Characteristics For Imaging And Image-Guided Therapy | US15305203 | 2015-04-24 | US20170168041A1 | 2017-06-15 | Bin Liu; Youyong Yuan; Guangxue Feng; Ben Zhong Tang; Wei Qin; Chongjing Zhang; Shidang Xu |
| A fluorophore or conjugated polymer with aggregation-induced emission characteristics useful for drug tracking and delivery, identification and labeling of biological subjects, such as cells or parts of a cell, as well as for imaging, and image-guided photodynamic therapy are described herein. | ||||||
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