子分类：
| 序号 | 专利名 | 申请号 | 申请日 | 公开（公告）号 | 公开（公告）日 | 发明人 |
|---|---|---|---|---|---|---|
| 161 | PROCESS FOR THE REDUCTIVE AMINATION AND SELECTIVE HYDROGENATION OF SUBSTRATES CONTAINING A SELECTED HALOGEN | US15678183 | 2017-08-16 | US20170342019A1 | 2017-11-30 | Kristof Moonen; Bart Vandeputte; Daan Scheldeman; Kim Dumoleijn |
| Disclosed is a process for performing a chemical reaction selected from reductive amination and hydrogenation of a first functional group in an organic feed substrate, which feed substrate comprises at least one further functional group containing a halogen atom, wherein the halogen atom is selected from the list consisting of chlorine, bromine, iodine, and combinations thereof, in the presence of hydrogen and a heterogeneous catalyst comprising at least one metal from the list of Pd, Rh, and Ru, together with at least a second metal from the list consisting of Ag, Ni, Co, Sn, Cu and Au. The process is preferably applied for the reductive amination of 2-chloro-benzaldehyde to form 2-chloro-benzyldimethylamine, as an intermediate in the production of agrochemically active compounds and microbiocides of the methoximinophenylglyoxylic ester series. Further disclosed is a composition rich in 2-chloro-benzyldimethylamine, further comprising an amount of 2-chloro-benzyl alcohol and being low in chlorotoluene isomers. | ||||||
| 162 | Process for preparing cyclododecanone | US14815014 | 2015-07-31 | US09533933B2 | 2017-01-03 | Kevin Micoine; Ralf Meier; Juergen Herwig; Martin Roos; Harald Haeger; Luca Cameretti; Jens Doering |
| Cyclododecanone (CDON) is prepared by epoxidizing cyclododecene (CDEN) to epoxycyclododecane (CDAN epoxide), and rearranging the CDAN epoxide to CDON to obtain a mixture comprising said CDON and CDEN, wherein CDEN is separated from the CDON-containing mixture and sent to the epoxidation to CDAN epoxide in step a. | ||||||
| 163 | Bisoxime Ester Photoinitiator and Preparation Method and Use Thereof | US15116932 | 2015-03-17 | US20160376226A1 | 2016-12-29 | Xiaochun Qian |
| A bisoxime ester photoinitiator as represented by general formula (I). By introducing a bisoxime ester group and a cycloalkylalkyl group into the chemical structure, this photoinitiator not only has excellent performance in aspects of storage stability, photosensitivity, developability, pattern integrity, and the like, but also exhibits obviously improved photosensitivity and thermal stability compared to similar photoinitiators. | ||||||
| 164 | Synthetic intermediate of 1-(2-deoxy-2-fluoro-4-thio-β-D-arabinofuranosyl) cytosine, synthetic intermediate of thionucleoside, and method for producing the same | US14873966 | 2015-10-02 | US09475835B2 | 2016-10-25 | Kouki Nakamura; Satoshi Shimamura; Junichi Imoto; Motomasa Takahashi; Katsuyuki Watanabe; Kenji Wada; Yuuta Fujino; Takuya Matsumoto; Makoto Takahashi; Hideki Okada; Takehiro Yamane; Takayuki Ito |
| A compound represented by a formula [1D] as shown below (wherein R1A, R1B, R2A, R2B, R3A and R3B represent a hydrogen atom, an optionally substituted C1-6 alkyl group, and the like) is useful as an intermediate for producing a thionucleoside, and the production method of the present invention is useful as a method for producing a thionucleoside. | ||||||
| 165 | PROCESS FOR PREPARING CYCLODODECANONE | US14814984 | 2015-07-31 | US20160031783A1 | 2016-02-04 | Kevin MICOINE; Ralf MEIER; Juergen HERWIG; Martin ROOS; Harald HAEGER; Luca CAMERETTI; Jens DOERING |
| Cyclododecanone (CDON) is prepared by epoxidizing cyclododecene (CDEN) to epoxycyclododecane (CDAN epoxide), and rearranging the CDAN epoxide to CDON to obtain a mixture comprising said CDON and cyclododecane (CDAN), wherein CDAN is separated from the CDON-containing mixture and oxidized to CDON. | ||||||
| 166 | METHOD FOR PRODUCING OXIME | US14655514 | 2013-12-12 | US20150353478A1 | 2015-12-10 | Masahiro HOSHINO; Yuta KIKUCHI; Sho TSUJIUCHI |
| Provided is a method for producing an oxime compound with satisfactory selectivity. Provide is a method for producing an oxime represented by the following formula (II): wherein R1 and R2 are respectively the same as defined below, the method including oxidizing an amine represented by the following formula (I): wherein R1 and R2 each independently represents a hydrogen atom, an optionally substituted hydrocarbon group, or an optionally substituted heterocyclic group (provided that R1 and R2 are not simultaneously hydrogen atoms), orR1 and R2, together with the carbon atom to which R1 and R2 are attached, form an optionally substituted alicyclic hydrocarbon group having 3 to 12 carbon atoms [hereinafter sometimes referred to as the amine compound (I)],with oxygen in the presence of a layered silicate. | ||||||
| 167 | Method for producing ketoxime | US14087511 | 2013-11-22 | US09133106B2 | 2015-09-15 | Shih-Yao Chao; Cheng-Fa Hsieh; Chien-Chang Chiang; Pin-To Yao |
| A method for producing a ketoxime is provided. The method includes the step of performing a reaction of a nitrogen-containing compound, ketone and an oxidant by using a titanium-silicon molecular sieve as a catalyst, so as to form the ketoxime, thereby increasing the yield and selectivity of the ketoxime. | ||||||
| 168 | SYNTHETIC INTERMEDIATE OF 1-(2-DEOXY-2-FLUORO-4-THIO-ß-D-ARABINOFURANOSYL)CYTOSINE, SYNTHETIC INTERMEDIATE OF THIONUCLEOSIDE, AND METHOD FOR PRODUCING THE SAME | US14621119 | 2015-02-12 | US20150152131A1 | 2015-06-04 | Kouki NAKAMURA; Satoshi SHIMAMURA; Junichi IMOTO; Motomasa TAKAHASHI; Katsuyuki WATANABE; Kenji WADA; Yuuta FUJINO; Takuya MATSUMOTO; Makoto TAKAHASHI; Hideki OKADA; Takehiro YAMANE; Takayuki ITO |
| A compound represented by a formula [1D] as shown below (wherein R1A, R1B, R2A, R2B, R3A and R3B represent a hydrogen atom, an optionally substituted C1-6 alkyl group, and the like) is useful as an intermediate for producing a thionucleoside, and the production method of the present invention is useful as a method for producing a thionucleoside. | ||||||
| 169 | Diterpenoid derivatives endowed of biological properties | US13951736 | 2013-07-26 | US08822692B2 | 2014-09-02 | Alberto Cerri; Mauro Gobbini; Marco Torri; Patrizia Ferrari; Mara Ferrandi; Giuseppe Bianchi |
| The present invention relates to new diterpenoid derivatives of formula (I), processes for their preparation, and to pharmaceutical compositions containing them for the treatment of cardiovascular disorders, urinary incontinence, asthma, or Alzheimer's disease and/or to prevent obstructive vascular lesions consequently to arteriotomy and/or angioplasty, and to prevent organ damage in hypertensive patients. | ||||||
| 170 | Method for preparing large-sized titanium-silicalite molecular sieve and method for preparing cyclohexanone oxime using the molecular sieve | US13344869 | 2012-01-06 | US08772194B2 | 2014-07-08 | Shih-Yao Chao; Cheng-Fa Hsieh; Chien-Chang Chiang; Ya-Ping Chen; Pin-To Yao |
| The present invention provides a method for preparing a large-sized titanium-silicalite molecular sieve, and a method for preparing cyclohexanone oxime using the large-sized titanium-silicalite molecular sieve. The method for preparing a large-sized titanium-silicalite molecular sieve includes preparing a mixture of a titanium source, a silicon source and a template agent; heating the mixture to form a gel mixture; mixing a colloidal silica with the gel mixture; heating the gel mixture mixed with the colloidal silica in a water bath; and calcining the gel mixture mixed with the colloidal silica. In the present invention, the average particle size of the large-sized titanium-silicalitem molecular sieve is more than 10 um, and the particle size distribution is centralized, so as to avoid the formation of titanium-oxygen-titanium bonding. The method for preparing cyclohexanone oxime using the large-sized titanium-silicalite molecular sieve results in high conversion rate, high selectivity and easy recovery. | ||||||
| 171 | METHOD FOR PRODUCING KETOXIME | US14087511 | 2013-11-22 | US20140179951A1 | 2014-06-26 | Shih-Yao Chao; Cheng-Fa Hsieh; Chien-Chang Chiang; Pin-To Yao |
| A method for producing a ketoxime is provided. The method includes the step of performing a reaction of a nitrogen-containing compound, ketone and an oxidant by using a titanium-silicon molecular sieve as a catalyst, so as to form the ketoxime, thereby increasing the yield and selectivity of the ketoxime. | ||||||
| 172 | Method for preparing titanium-silicalite molecular sieve and method for preparing cyclohexanone oxime using the molecular sieve | US13344995 | 2012-01-06 | US08753998B2 | 2014-06-17 | Chien-Chang Chiang; Cheng-Fa Hsieh; Pin-To Yao; Shih-Yao Chao |
| The present invention provides a method for preparing a titanium-silicalite molecular sieve, and a method for preparing cyclohexanone oxime using the titanium-silicalite molecular sieve. The method for preparing a titanium-silicalite molecular sieve includes the steps of preparing a mixture of a titanium source, a silicon source and a template agent, wherein the titanium source has a structure of formula (I); heating the mixture to form a gel mixture; mixing the gel mixture with water; heating the gel mixture mixed with the water in a water bath; and calcining the gel mixture mixed with the water. The method using the titanium-silicalite molecular sieve for preparing cyclohexanone oxime results in high conversion rate and high selectivity. | ||||||
| 173 | Oxidation Of Cyclohexylbenzene | US13819951 | 2011-08-16 | US20140148569A1 | 2014-05-29 | Jihad Mohammed Dakka; Francisco Manuel Benitez; Bryan Amrutlal Patel; Edmund John Mozeleski |
| In a process for oxidizing a feed comprising cyclohexylbenzene, the feed is contacted with oxygen and an oxidation catalyst in a plurality of reaction zones connected in series, the contacting being conducted under conditions being effective to oxidize part of the cyclohexylbenzene in the feed to cyclohexylbenzene hydroperoxide in each reaction zone. At least one of the plurality of reaction zones has a reaction condition that is different from another of the plurality of reaction zones. The different reaction conditions may include one or more of (a) a progressively decreasing temperature and (b) a progressively increasing oxidation catalyst concentration as the feed flows from one reaction zone to subsequent reaction zones in the series. | ||||||
| 174 | DITERPENOID DERIVATIVES ENDOWED OF BIOLOGICAL PROPERTIES | US13951736 | 2013-07-26 | US20130310423A1 | 2013-11-21 | Alberto Cerri; Mauro Gobbini; Marco Torri; Patrizia Ferrari; Mara Ferrandi; Giuseppe Bianchi |
| The present invention relates to new diterpenoid derivatives of formula (I), processes for their preparation, and to pharmaceutical compositions containing them for the treatment of cardiovascular disorders, urinary incontinence, asthma, or Alzheimer's disease and/or to prevent obstructive vascular lesions consequently to arteriotomy and/or angioplasty, and to prevent organ damage in hypertensive patients. | ||||||
| 175 | Ammoximation process | US12666343 | 2008-07-02 | US08450526B2 | 2013-05-28 | Robert Raja; John Meurig Thomas |
| A redox ammoximation process in which a ketone or aldehyde is reacted with ammonia and oxygen in the presence of a catalyst; wherein the catalyst is an aluminophosphate based redox catalyst having at least two different redox catalytic sites comprising different transition metal atoms. | ||||||
| 176 | Ammoximation process | US13139930 | 2010-01-06 | US08444917B2 | 2013-05-21 | Robert Raja; Alexander James Paterson |
| A redox ammoximation process in which a ketone or aldehyde is reacted with ammonia and oxygen in the presence of a catalyst, wherein: the catalyst is an aluminophosphate based redox catalyst having the qualitative general formula (I) M1M2AlPO-5 (I) in which M1 is at least one transition metal atom having redox catalytic capability; M2 is at least one metal atom in the (IV) oxidation state; M1 and M2 are different from each other; and a proportion of the phosphorous atoms in the M1M2AlPO-5 type structure are replaced by M2 atoms. | ||||||
| 177 | ORDERED MESOPOROUS TITANOSILICATE AND THE PROCESS FOR THE PREPARATION THEREOF | US13811235 | 2011-07-20 | US20130116453A1 | 2013-05-09 | Srinivas Darbha; Anuj Kumar |
| The invention discloses three-dimensional, ordered, mesoporous titanosilicates wherein the Ti is in a tetrahedral geometry and exclusively substituted for Si in the silica framework. Such titanosilicates find use as catalysts for epoxidation, hydroxylation, C—H bond oxidation, oxidation of sulfides, aminolysis of epoxide and amoximation, with approx. 100% selectivity towards the products. | ||||||
| 178 | Process of racemisation of optically active alpha aminoacetals | US12601067 | 2008-05-21 | US08350092B2 | 2013-01-08 | Muriel Albalat; Geraldine Primazot; Didier Wilhelm; Jean-Claude Vallejos |
| The invention relates to a process for preparing α-aminoacetals substantially in racemic form, comprising a step of oxidizing optically enriched α-aminoacetals to the corresponding oximes, in the presence of a catalyst, and a step of reducing the oximes thus obtained. | ||||||
| 179 | TITANIUM-SILICALITE MOLECULAR SIEVE, METHOD FOR PREPARING THE SAME AND METHOD FOR PREPARING CYCLOHEXANONE OXIME USING THE MOLECULAR SIEVE | US13345089 | 2012-01-06 | US20120277468A1 | 2012-11-01 | Ya-Ping Chen; Cheng-Fa Hsieh; Pin-To Yao; Chien-Chang Chiang |
| The present invention provides a titanium-silicalite molecular sieve and a method for preparing the same. The method includes the steps of preparing a mixture of a titanium source, a silicon source, a transition metal source, a template agent and water; heating the mixture to form a gel mixture; heating the gel mixture in a water bath; and calcining the gel mixture after the gel mixture in the water bath to form the titanium-silicalite molecular sieve. The present invention further provides a method for preparing cyclohexanone oxime by using the titanium-silicalite molecular sieve as the catalyst which results in high conversion rate, high selectivity and high usage efficiency of hydrogen peroxide. | ||||||
| 180 | METHOD FOR PREPARING TITANIUM-SILICALITE MOLECULAR SIEVE AND METHOD FOR PREPARING CYCLOHEXANONE OXIME USING THE MOLECULAR SIEVE | US13344995 | 2012-01-06 | US20120271066A1 | 2012-10-25 | Chien-Chang Chiang; Cheng-Fa Hsieh; Pin-To Yao; Shih-Yao Chao |
| The present invention provides a method for preparing a titanium-silicalite molecular sieve, and a method for preparing cyclohexanone oxime using the titanium-silicalite molecular sieve. The method for preparing a titanium-silicalite molecular sieve includes the steps of preparing a mixture of a titanium source, a silicon source and a template agent, wherein the titanium source has a structure of formula (I); heating the mixture to form a gel mixture; mixing the gel mixture with water; heating the gel mixture mixed with the water in a water bathe; and calcining the gel mixture mixed with the water. The method using the titanium-silicalite molecular sieve for preparing cyclohexanone oxime results in high conversion rate and high selectivity. | ||||||
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