41 |
EXPANDED RADIX FOR POLYMERIC TAGS |
PCT/US2012065929 |
2012-11-19 |
WO2013085710A3 |
2013-08-01 |
WEINER MICHAEL P |
A method having steps of (a) providing nucleic acids having a tag sequence (N1)n(N2)n... (Nx)n, wherein N1, N2 and Nx are nucleotides that complement different nucleotides, respectively, wherein n is an integer that can differ for N1, N2 and Nx; (b) detecting the nucleic acids individually and under conditions to distinguish signal intensities for (N1)n sequences having different values for n, (N2)n sequences having different values for n and. (Nx)n sequences having different values for n; and (c) distinguishing the tags based on the signal intensities. |
42 |
NOVEL BIOMARKER AND USES THEREOF IN DIAGNOSIS, TREATMENT OF AUTISM |
PCT/SE2011051504 |
2011-12-13 |
WO2012082056A1 |
2012-06-21 |
MOMENI NAGHI; PERSSON BENGT L |
A new biomarker, a peptide having sequence SSKITHRIHWESASLLR*, wherein the side chain of the C-terminal arginine denoted with the asterisk is lacking the NH2- C=NH moiety normally present in the side chain. Usefulness of the biomarker in the diagnosis of neurological and/or neuropsychiatric disorders (in particular autism) is disclosed, as well as are methods for determining the concentration of the new biomarker and antibodies directed to the new biomarker. Treatment of autism, comprising administering a complement factor I inhibitor to the subject. |