专利检索_ .醛裂解酶专利检索_ .醛裂解酶专利检索查询

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序号	专利名	申请号	申请日	公开（公告）号	公开（公告）日	发明人
1	Nucleic Acids and Proteins and Methods for Making and Using Them	US11817403	2006-03-03	US20100011456A1	2010-01-14	Eric J. Mathur; Cathy Chang
The invention provides polypeptides, including enzymes, structural proteins and binding proteins, polynucleotides encoding these polypeptides, and methods of making and using these polynucleotides and polypeptides. Polypeptides, including enzymes and antibodies, and nucleic acids of the invention can be used in industrial, experimental, food and feed processing, nutritional and pharmaceutical applications, e.g., for food and feed supplements, colorants, neutraceuticals, cosmetic and pharmaceutical needs.
2	NUCLEIC ACIDS AND PROTEINS AND METHODS FOR MAKING AND USING THEM	US14630006	2015-02-24	US20150240226A1	2015-08-27	Eric J. Mathur; Cathy Chang
The invention provides polypeptides, including enzymes, structural proteins and binding proteins, polynucleotides encoding these polypeptides, and methods of making and using these polynucleotides and polypeptides. Polypeptides, including enzymes and antibodies, and nucleic acids of the invention can be used in industrial, experimental, food and feed processing, nutritional and pharmaceutical applications, e.g., for food and feed supplements, colorants, neutraceuticals, cosmetic and pharmaceutical needs.
3	Nucleic Acids and Proteins and Methods for Making and Using Them	US13400365	2012-02-20	US20120266329A1	2012-10-18	Eric J. Mathur; Cathy Chang
The invention provides polypeptides, including enzymes, structural proteins and binding proteins, polynucleotides encoding these polypeptides, and methods of making and using these polynucleotides and polypeptides. Polypeptides, including enzymes and antibodies, and nucleic acids of the invention can be used in industrial, experimental, food and feed processing, nutritional and pharmaceutical applications, e.g., for food and feed supplements, colorants, neutraceuticals, cosmetic and pharmaceutical needs.
4	Metabolic engineering of the shikimate pathway	US14342335	2012-08-31	US09540652B2	2017-01-10	Darmawi Juminaga; Jay D. Keasling
The present disclosure relates to engineered microorganisms that produce amino acids and amino acid intermediates. In particular, the disclosure relates to recombinant nucleic acids encoding operons that increase production of aromatic amino acids and the aromatic amino acid intermediate shikimate; microorganisms with increased production of aromatic amino acids and the aromatic amino acid intermediate shikimate; and methods related to the production of aromatic amino acids, the aromatic amino acid intermediate shikimate, and commodity chemicals derived therefrom.
5	Nucleic acids and proteins and methods for making and using them	US13400365	2012-02-20	US08962800B2	2015-02-24	Eric J. Mathur; Cathy Chang
The invention provides polypeptides, including enzymes, structural proteins and binding proteins, polynucleotides encoding these polypeptides, and methods of making and using these polynucleotides and polypeptides. Polypeptides, including enzymes and antibodies, and nucleic acids of the invention can be used in industrial, experimental, food and feed processing, nutritional and pharmaceutical applications, e.g., for food and feed supplements, colorants, neutraceuticals, cosmetic and pharmaceutical needs.
6	METABOLIC ENGINEERING OF THE SHIKIMATE PATHWAY	US14342335	2012-08-31	US20150044734A1	2015-02-12	Darmawi Juminaga; Jay D. Keasling
The present disclosure relates to engineered microorganisms that produce amino acids and amino acid intermediates. In particular, the disclosure relates to recombinant nucleic acids encoding operons that increase production of aromatic amino acids and the aromatic amino acid intermediate shikimate; microorganisms with increased production of aromatic amino acids and the aromatic amino acid intermediate shikimate; and methods related to the production of aromatic amino acids, the aromatic amino acid intermediate shikimate, and commodity chemicals derived therefrom.
7	Nucleic acids and proteins and methods for making and using them	US11817403	2006-03-03	US08119385B2	2012-02-21	Eric J. Mathur; Cathy Chang
The invention provides polypeptides, including enzymes, structural proteins and binding proteins, polynucleotides encoding these polypeptides, and methods of making and using these polynucleotides and polypeptides. Polypeptides, including enzymes and antibodies, and nucleic acids of the invention can be used in industrial, experimental, food and feed processing, nutritional and pharmaceutical applications, e.g., for food and feed supplements, colorants, neutraceuticals, cosmetic and pharmaceutical needs.
8	クピンスーパーファミリーのタンパク質により触媒される（Ｒ）−選択的ニトロアルドール反応	JP2016571420	2015-06-12	JP2017517264A	2017-06-29	ケルシュティンシュタイナー，; マンダナグルーバー，; ロマーナヴィードナー，; ヘルムートシュワブ，
本発明は、キラルβ−ニトロアルコール化合物を作製するための方法に関する。本発明は、特に、ヘンリー反応をエナンチオ選択的に触媒できる(R)−選択的クピン−ニトロアルドラーゼに関し、ニトロアルカン化合物およびクピン−ニトロアルドラーゼの存在下でアルデヒド化合物またはケトン化合物が、対応するβ−ニトロアルコール化合物に変換される。【選択図】図2
9	再生可能資源から化合物を生成するための高収量経路	JP2016515437	2014-09-17	JP2016533162A	2016-10-27	チョカワラ、ハーシャル
本開示は、1−ブタノール、酪酸、コハク酸、1,4−ブタンジオール、1−ペンタノール、ペンタン酸、グルタル酸、1,5−ペンタンジオール、1−ヘキサノール、ヘキサン酸、アジピン酸、1,6−ヘキサンジオール、6−ヒドロキシヘキサン酸、ε−カプロラクトン、6−アミノ−ヘキサン酸、ε−カプロラクタム、ヘキサメチレンジアミン、7〜25炭素長の直鎖脂肪酸および直鎖脂肪アルコール、セバシン酸またはドデカン二酸等の化合物を調製するための方法、組成物、および、天然に存在しない微生物生物であって、前記方法は、a)アルドール付加を介して、CNアルデヒドおよびピルベートをCN+3β−ヒドロキシケトン中間体に変換する工程;およびb)酵素的工程または酵素的工程と化学的工程との組み合わせを介して、該CN+3β−ヒドロキシケトン中間体を該化合物に変換する工程を含む、方法、組成物、および、天然に存在しない微生物生物に関する。【選択図】図1
10	A HIGH YIELD ROUTE FOR THE PRODUCTION OF COMPOUNDS FROM RENEWABLE SOURCES	EP14846017.3	2014-09-17	EP3047030A2	2016-07-27	CHOKHAWALA, Harshal
Provided herein are methods, compositions, and non-naturally occurring microbial organism for preparing compounds such as1-butanol, butyric acid, succinic acid, 1,4-butanediol, 1-pentanol, pentanoic acid, glutaric acid, 1,5-pentanediol, 1-hexanol, hexanoic acid, adipic acid, 1,6-hexanediol, 6-hydroxy hexanoic acid, ε-Caprolactone, 6-amino-hexanoic acid, ε-Caprolactam, hexamethylenediamine, linear fatty acids and linear fatty alcohols that are between 7-25 carbons long, linear alkanes and linear -alkenes that are between 6-24 carbons long, sebacic acid and dodecanedioic acid comprising: a) converting a C _N aldehyde and pyruvate to a C _N+3 -hydroxyketone intermediate through an aldol addition; and b) converting the C _N+3-hydroxyketone intermediate to the compounds through enzymatic steps, or a combination of enzymatic and chemical steps.
11	NUCLEIC ACIDS AND PROTEINS AND METHODS FOR MAKING AND USING THEM	EP06736890	2006-03-03	EP1856291A4	2009-04-01	MATHUR ERIC; CHANG CATHY

12	(R)-SELECTIVE NITROALDOL REACTION CATALYSED BY PROTEINS OF THE CUPIN SUPERFAMILY	EP15728854.9	2015-06-12	EP3155115A1	2017-04-19	STEINER, Kerstin; GRUBER, Mandana; WIEDNER, Romana; SCHWAB, Helmut
The present invention relates to a method for producing chiral β-nitro alcohol compounds. The invention relates in particular to an (R)-selective cupin-nitroaldolase, which enantioselectively can catalyze the Henry reaction, wherein an aldehyde or ketone compound is converted to the corresponding β-nitro alcohol compound in the presence of a nitroalkane compound and a cupin-nitroaldolase.
13	A HIGH YIELD ROUTE FOR THE PRODUCTION OF COMPOUNDS FROM RENEWABLE SOURCES	EP14846017	2014-09-17	EP3047030A4	2017-02-22	CHOKHAWALA HARSHAL
Provided herein are methods, compositions, and non-naturally occurring microbial organism for preparing compounds such as 1-butanol, butyric acid, succinic acid, 1,4-butanediol, 1-pentanol, pentanoic acid, glutaric acid, 1,5-pentanediol, 1-hexanol, hexanoic acid, adipic acid, 1,6-hexanediol, 6-hydroxy hexanoic acid, ε-Caprolactone, 6-amino-hexanoic acid, ε-Caprolactam, hexamethylenediamine, linear fatty acids and linear fatty alcohols that are between 7-25 carbons long, linear alkanes and linear α-alkenes that are between 6-24 carbons long, sebacic acid and dodecanedioic acid comprising: a) converting a CN aldehyde and pyruvate to a CN+3 β-hydroxyketone intermediate through an aldol addition; and b) converting the CN+3β-hydroxyketone intermediate to the compounds through enzymatic steps, or a combination of enzymatic and chemical steps.
14	NUCLEIC ACIDS AND PROTEINS AND METHODS FOR MAKING AND USING THEM	EP06736890.2	2006-03-03	EP1856291A2	2007-11-21	MATHUR, Eric; CHANG, Cathy
The invention provides polypeptides, including enzymes, structural proteins and binding proteins, polynucleotides encoding these polypeptides, and methods of making and using these polynucleotides and polypeptides. Polypeptides, including enzymes and antibodies, and nucleic acids of the invention can be used in industrial, experimental, food and feed processing, nutritional and pharmaceutical applications, e.g., for food and feed supplements, colorants, neutraceuticals, cosmetic and pharmaceutical needs.
15	NUCLEIC ACIDS AND PROTEINS AND METHODS FOR MAKING AND USING THEM	PCT/US2006007642	2006-03-03	WO2006096527A3	2007-11-22	MATHUR ERIC; CHANG CATHY
The invention provides polypeptides, including enzymes, structural proteins and binding proteins, polynucleotides encoding these polypeptides, and methods of making and using these polynucleotides and polypeptides. Polypeptides, including enzymes and antibodies, and nucleic acids of the invention can be used in industrial, experimental, food and feed processing, nutritional and pharmaceutical applications, e.g., for food and feed supplements, colorants, neutraceuticals, cosmetic and pharmaceutical needs.
16	A HIGH YIELD ROUTE FOR THE PRODUCTION OF COMPOUNDS FROM RENEWABLE SOURCES	PCT/US2014056175	2014-09-17	WO2015042201A3	2015-06-04	CHOKHAWALA HARSHAL
Provided herein are methods, compositions, and non-naturally occurring microbial organism for preparing compounds such as1-butanol, butyric acid, succinic acid, 1,4-butanediol, 1-pentanol, pentanoic acid, glutaric acid, 1,5-pentanediol, 1-hexanol, hexanoic acid, adipic acid, 1,6-hexanediol, 6-hydroxy hexanoic acid, ε-Caprolactone, 6-amino-hexanoic acid, ε-Caprolactam, hexamethylenediamine, linear fatty acids and linear fatty alcohols that are between 7-25 carbons long, linear alkanes and linear -alkenes that are between 6-24 carbons long, sebacic acid and dodecanedioic acid comprising: a) converting a CN aldehyde and pyruvate to a CN+3 -hydroxyketone intermediate through an aldol addition; and b) converting the CN+3 -hydroxyketone intermediate to the compounds through enzymatic steps, or a combination of enzymatic and chemical steps.

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