A HIGH YIELD ROUTE FOR THE PRODUCTION OF COMPOUNDS FROM RENEWABLE SOURCES |
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| 申请号 | PCT/US2014056175 | 申请日 | 2014-09-17 | 公开(公告)号 | WO2015042201A3 | 公开(公告)日 | 2015-06-04 |
| 申请人 | ZYMOCHEM INC; CHOKHAWALA HARSHAL; | 发明人 | CHOKHAWALA HARSHAL; | ||||
| 摘要 | Provided herein are methods, compositions, and non-naturally occurring microbial organism for preparing compounds such as1-butanol, butyric acid, succinic acid, 1,4-butanediol, 1-pentanol, pentanoic acid, glutaric acid, 1,5-pentanediol, 1-hexanol, hexanoic acid, adipic acid, 1,6-hexanediol, 6-hydroxy hexanoic acid, ε-Caprolactone, 6-amino-hexanoic acid, ε-Caprolactam, hexamethylenediamine, linear fatty acids and linear fatty alcohols that are between 7-25 carbons long, linear alkanes and linear -alkenes that are between 6-24 carbons long, sebacic acid and dodecanedioic acid comprising: a) converting a CN aldehyde and pyruvate to a CN+3 -hydroxyketone intermediate through an aldol addition; and b) converting the CN+3 -hydroxyketone intermediate to the compounds through enzymatic steps, or a combination of enzymatic and chemical steps. | ||||||
| 权利要求 | |||||||
| 说明书全文 | |||||||
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