| 序号 | 专利名 | 申请号 | 申请日 | 公开（公告）号 | 公开（公告）日 | 发明人 |
|---|---|---|---|---|---|---|
| 1 | Genes associated with obesity and methods for using the same | US10608865 | 2003-06-27 | US20050074767A1 | 2005-04-07 | David Lewin; Timothy Stewart |
| The instant invention is concerned with genes associated with obesity. Additionally, the invention provides methods of using the differential expression of these genes associated with obesity to diagnose and treat obesity, as well as to screen for compounds useful for treating obesity. | ||||||
| 2 | Methods and compositions for RNA interference | US11413795 | 2006-04-28 | US20070020652A1 | 2007-01-25 | A. Alvarado; Peter Reddien; Adam Bermange |
| The invention relates to improved methods of attenuating expression of a target gene in a eukaryotic cell with dsRNA, identifying nucleic acid sequences responsible for conferring a particular phenotype to a cell, alleviating pest infestation in plants, and altering gene expression in an undifferentiated stem cell or the differentiated progeny thereof. Transcription of the RNA, which will form the dsRNA, is terminated by one or more terminators sequences, thereby increasing the efficiency of inhibition. | ||||||
| 3 | ASSAYS FOR EVALUATING CELL CULTURE REAGENTS | US15578736 | 2016-06-01 | US20180171362A1 | 2018-06-21 | Jessica Mondia; Alan Gilbert; Maureen Lanan |
| Some aspects of the present disclosure provide methods, compositions and kits for identifying one or more reagents, such as a culture medium, that are effective for recombinant protein production. | ||||||
| 4 | GENES ASSOCIATED WITH OBESITY AND METHODS FOR USING THE SAME | US11625085 | 2007-01-19 | US20070207148A1 | 2007-09-06 | David Lewin; Timothy Stewart |
| The instant invention is concerned with genes associated with obesity. Additionally, the invention provides methods of using the differential expression of these genes associated with obesity to diagnose and treat obesity, as well as to screen for compounds useful for treating obesity. | ||||||
| 5 | Methods for using genes associated with genes and obesity-related obesity | JP2001531869 | 2000-10-19 | JP2003512038A | 2003-04-02 | ティモシー スチュアート，; デイビッド レウィン， |
| (57)【要約】 本発明は肥満に関連した遺伝子に関する。 さらに、本発明は、肥満を診断および処置するために、ならびに肥満の処置に有用な化合物についてスクリーニングするために、肥満に関連したこれらの遺伝子の差次的な発現を使用する方法を提供する。 本発明の方法は、ＯＢ１〜６からなる群から選択される１つ以上の核酸配列を発現可能な細胞を含む試験細胞集団を、被験体から提供する工程、試験細胞集団における核酸配列の１つ以上の発現を検出する工程を包含する。 | ||||||
| 6 | ASSAYS FOR EVALUATING CELL CULTURE REAGENTS | EP16730599.4 | 2016-06-01 | EP3303609A1 | 2018-04-11 | MONDIA, Jessica; GILBERT, Alan; LANAN, Maureen |
| Some aspects of the present disclosure provide methods, compositions and kits for identifying one or more reagents, such as a culture medium, that are effective for recombinant protein production. | ||||||
| 7 | GENES ASSOCIATED WITH OBESITY AND METHODS FOR USING THE SAME | EP00972280.2 | 2000-10-19 | EP1222313A2 | 2002-07-17 | STEWART, Timothy; LEWIN, David |
| The instant invention is concerned with genes associated with obesity. Additionally, the invention provides methods of using the differential expression of these genes associated with obesity to diagnose and treat obesity, as well as to screen for compounds useful for treating obesity. | ||||||
| 8 | IMPROVED METHODS AND COMPOSITIONS FOR RNA INTERFERENCE | PCT/US2004037475 | 2004-11-10 | WO2005047300A2 | 2005-05-26 | ALVARADO A SANCHEZ; REDDIEN PETER WALTHOUR; BERMANGE ADAM LEWIS |
| The invention relates to improved methods of attenuating expression of a target gene in a eukaryotic cell with dsRNA, identifying nucleic acid sequences responsible for conferring a particular phenotype to a cell, alleviating pest infestation in plants, and altering gene expression in an undifferentiated stem cell or the differentiated progeny thereof. Transcription of the RNA, which will form the dsRNA, is terminated by one or more terminators sequences, thereby increasing the efficiency of inhibition. | ||||||
| 9 | GENES ASSOCIATED WITH OBESITY AND METHODS FOR USING THE SAME | PCT/US0028932 | 2000-10-19 | WO0129071A3 | 2002-05-02 | STEWART TIMOTHY; LEWIN DAVID |
| The instant invention is concerned with genes associated with obesity. Additionally, the invention provides methods of using the differential expression of these genes associated with obesity to diagnose and treat obesity, as well as to screen for compounds useful for treating obesity. | ||||||
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