序号 专利名 申请号 申请日 公开(公告)号 公开(公告)日 发明人
21 Process for producing starch-containing food, and enzyme preparation for modification of starch-containing food JP2007164867 2007-06-22 JP2008194024A 2008-08-28 YAMADA NORIAKI; OGAWA TEPPEI; MARUYAMA AKIKO; OKAMOTO TAKESHI; WAKABAYASHI HIDEHIKO
<P>PROBLEM TO BE SOLVED: To provide the process of producing starch-containing food improved in physical property and eating quality, and to provide an enzyme preparation for the modification of the starch-containing food. <P>SOLUTION: The process of producing the starch-containing food employs a transglutaminase and an enzyme having a glycosyltransferase activity which can covert an α-1,4 bond to an α-1,6 bond. The enzyme preparation is yielded by combining the transglutaminase and the enzyme having the glycosyltransferase activity which can covert the α-1,4 bond to the α-1,6 bond. <P>COPYRIGHT: (C)2008,JPO&INPIT
22 전분 함유 식품의 제조 방법 및 전분 함유 식품 개질용의 효소 제제 KR1020087031489 2007-06-27 KR1020090024187A 2009-03-06 야마다노리아키; 오가와데페이; 마루야마아키코; 오카모토다케시; 와카바야시히데히코
A starch-containing food can be improved in its quality by using an enzyme having a glycosyltransferase activity which can covert an alpha-1,4 bond to an alpha-1,6 bond and a transglutaminase.
23 슈도노카디아 오토트로피카 유래의 폴리엔 특이적인 신규 당전이효소 KR1020130130264 2013-10-30 KR101552400B1 2015-09-10 김응수; 이미진; 김혜진
본발명은슈도노카디아오토트로피카() 유래의폴리엔특이적인신규당전이효소(glycosyltransferase)에관한것으로, 본발명은서열번호 1의아미노산서열을포함하는당전이효소(glycosyltransferase) 및상기당전이효소를암호화하는유전자를제공한다. 또한, 본발명은상기유전자를포함하는재조합발현벡터, 상기재조합발현벡터로형질전환된재조합미생물을제공한다. 또한, 본발명은상기형질전환된재조합미생물을배양하는단계; 및상기배양된재조합미생물로부터당전이효소를분리하는단계를포함하는당전이효소생산방법을제공한다.
24 반코마이신 유도체 및 그의 제조방법 KR1020080070125 2008-07-18 KR1020100009291A 2010-01-27 우진석; 송재경; 김대희; 강선엽; 양지영; 서원민; 심상희; 오태진
PURPOSE: A vancomycin derivative in which monosaccharide is bound is provided to ensure tolerance to vancomycin and has high physiological activity. CONSTITUTION: A vancomycin derivative has vancomycin of chemical formula 1 or D-glucose of pseudo-vancomycin of chemical formula 2 which one or more monosaccharide is bound. The monosaccharide is glucose, fructose, mannose, galactose, ribose, or amino saccharide. The monosaccharide is galactose, the galactose is bound with sialic acid. The amino acid saccharide is sialic acid. A method for preparing the vancomyxin derivative comprises: a step of performing glycosyl transition of vancomycin or pseudo vancomycin aglycon to obtain one or more monosaccharide-bound vancomycin derivative complex; and a step of purifying the monosaccharide-bound vancomycin derivative complex through chromatography.
25 Production of Glycosylated Nootkatol in Recombinant Hosts US15774134 2016-11-14 US20180327723A1 2018-11-15 Dayal Saran; Jorgen Hansen; Philippe Prochasson; Patrick Roussel; Laura Occhipinti; Alexei Ouspenski; Sumire Honda Malca
The invention relates to methods for producing glycosylated nootkatol. In particular, a recombinant host comprising a gene encoding a UDP-glycosyltransferase polypeptide capable of glycosylating nootkatol is disclosed. Glycosylation of nootkatol detoxifies nootkatol, allowing for greater production of (glycosylated-)nootkatol, a precursor of nootkatone, and therefore greater production of nootkatone. The invention also relates to methods of converting non-toxic, glycosylated nootkatol produced by a recombinant host to nootkatol, wherein the nootkatol can subsequently be converted to large quantities of nootkatone to be used in flavorings, perfumes, and/or insect repellents.
26 POLYPEPTIDES CAPABLE OF PRODUCING GLUCANS HAVING ALPHA-1,2 BRANCHES AND USE OF THE SAME US15767689 2016-11-22 US20180282385A1 2018-10-04 Qiong Cheng; Robert DiCosimo; Jahnavi Chandra Prasad; Zhenghong Zhang
Disclosed herein are proteins capable of forming glucans having alpha-1,2 linkages/branches, reactions and methods for producing such glucan, compositions comprising such glucan, and various applications thereof.
27 Recombinant production of steviol glycosides US15366209 2016-12-01 US10081826B2 2018-09-25 Guohong Mao; Xiaodan Yu
Recombinant polypeptides having UDP-glycosyltransferase activities, including a 1,2-19-O-glucose glycosylation activity and a 1,2-13-O-glucose glycosylation activity for synthesizing of steviol glucosides, are provided. A method of producing a steviol glycoside composition using such recombinant polypeptide is also provided. Also disclosed are steviol glycosides referred to as rebaudioside Z1 and rebaudioside Z2.
28 Bacteria with improved metabolic capacity US15036376 2014-11-13 US09902965B2 2018-02-27 Frederick R. Blattner; David A. Frisch; Robert E. Novy; Terrance M. Henker; Eric A. Steffen; Jose A. Sanchez; Christopher R. Blattner; Hyunsic Choi; Gyorgy Posfai
E. coli bacteria comprising genetic modifications to enhance fermentability and production of protein and nucleic acids are provided.
29 RECOMBINANT PRODUCTION OF STEVIOL GLYCOSIDES US15631083 2017-06-23 US20170298404A1 2017-10-19 Guohong Mao; Xiaodan Yu
Recombinant polypeptides having UDP-glycosyltransferase activities, including a 1,2-19-O-glucos glycosylation activity and a 1,2-13-O-glucos glycosylation activity for synthesizing of steviol glucosides, are provided. A method of producing a steviol glycoside composition using such recombinant polypeptide is also provided. Also disclosed are steviol glycosides referred to as rebaudioside Z1 and rebaudioside Z2.
30 Thermophilic and thermoacidophilic glycosylation genes and enzymes from alicyclobacillus acidocaldarius and related organisms, methods US14977349 2015-12-21 US09677054B2 2017-06-13 David N Thompson; William A Apel; Vicki S Thompson; David W Reed; Jeffrey A Lacey
Isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from Alicyclobacillus acidocaldarius are provided. Further provided are methods for glycosylating and/or post-translationally modifying proteins using isolated and/or purified polypeptides and nucleic acid sequences from Alicyclobacillus acidocaldarius.
31 BACTERIA WITH IMPROVED METABOLIC CAPACITY US15036376 2014-11-13 US20160298126A1 2016-10-13 Frederick R. BLATTNER; David A. FRISCH; Robert E. NOVY; Terrance M. HENKER; Eric A. STEFFEN; Jose A. SANCHEZ; Christopher R. BLATTNER; Hyunsic CHOI; Gyorgy POSFAI
E. coli bacteria comprising genetic modifications to enhance fermentability and production of protein and nucleic acids are provided.
32 NOVEL POLYENE-SPECIFIC GLYCOSYLTRANSFERASE DERIVED FROM PSEUDONOCARDIA AUTOTROPHICA US14912604 2014-10-28 US20160201038A1 2016-07-14 Eung Soo KIM; Mi Jin LEE; Hye Jin KIM
Disclosed is a novel polyene-specific glycosyltransferase derived from Pseudonocardia autotrophica. The glycosyltransferase includes an amino acid sequence of SEQ ID NO: 1 and a gene encoding the glycosyltransferase. The glycosyltransferase is produced by a method which includes the steps of: culturing transgenic recombinant microorganisms; and isolating glycosyltransferase from the cultured recombinant microorganisms.
33 THERMOPHILIC AND THERMOACIDOPHILIC GLYCOSYLATION GENES AND ENZYMES FROM ALICYCLOBACILLUS ACIDOCALDARIUS AND RELATED ORGANISMS, METHODS US14977349 2015-12-21 US20160130568A1 2016-05-12 David N Thompson; William A Apel; Vicki S Thompson; David W Reed; Jeffrey A Lacey
Isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from Alicyclobacillus acidocaldarius are provided. Further provided are methods for glycosylating and/or post-translationally modifying proteins using isolated and/or purified polypeptides and nucleic acid sequences from Alicyclobacillus acidocaldarius.
34 Efficient Production of Steviol Glycosides in Recombinant Hosts US14764898 2014-02-11 US20150361476A1 2015-12-17 Ernesto Simon; Iben Nordmark Anderson; Michael Dalgaard Mikkelsen; Jorgen Hansen; Veronique Douchin
Recombinant microorganisms are disclosed that produce steviol glycosides and have altered expression of one or more endogenous transporter or transcription factor genes, or that overexpress one or more heterologous transporters, leading to increased excretion of steviol glycosides of interest.
35 Tumor specific oligosaccharide epitopes and use thereof US10525011 2003-08-20 US08697061B2 2014-04-15 Jari Natunen; Tero Satomaa
The present invention describes oligosaccharide sequences, which are specifically expressed by human tumors. The present invention is related to a method of determining an oligosaccharide sequence, which comprises a tumor specific terminal N-acetylglucosamine residue, in a biological sample, the presence of said sequence in said sample being an indication of the presence of cancer. The present invention provides antigenic substances comprising said oligosaccharide sequences in a polyvalent form and it further provides diagnostic agents, pharmaceutical compositions and cancer vaccines comprising said oligosaccharide sequences or substances binding to said oligosaccharide sequences. The present invention is also related to methods for the treatment of cancer.
36 TRANSGENIC PLANTS WITH ENHANCED AGRONOMIC TRAITS US13299402 2011-11-18 US20120066787A1 2012-03-15 Savitha Madappa; Pranesh Badami; Dhanalakshmi Ramachandra; S. Sangeetha; K. R. Vidya; Stephen M. Duff; Steve S. He; Linda L. Lutfiyya; T. V. Venkatesh
This invention provides transgenic plant cells with recombinant DNA for expression of proteins that are useful for imparting enhanced agronomic trait(s) to transgenic crop plants. This invention also provides transgenic plants and progeny seed comprising the transgenic plant cells where the plants are selected for having an enhanced trait selected from the group of traits consisting of enhanced water use efficiency, enhanced cold tolerance, increased yield, enhanced nitrogen use efficiency, enhanced seed protein and enhanced seed oil. Also disclosed are methods for manufacturing transgenic seed and plants with enhanced traits.
37 Enzyme for Obtaining Prebiotic Oligosaccharides US11721942 2005-12-15 US20090275085A1 2009-11-05 Francisco Jose Plou Gasca; Maria Aranzazu Gomez De Segura Ulgado; Miguel Alcade Galeote
An industrially viable process of obtaining prebiotic oligosaccharides using a new Xanthophyllomyces dendrorhous enzyme, characterized by showing α-glucosidase activity is provided. A process of obtaining an enzymatic product with α-glucosidase activity as well as the substantially pure enzyme with α-glucosidase activity, are also provided. The enzymatic product and the enzyme have a high action spectrum and a high specific activity as positive aspects. Prebiotic oligosacchartdes are used in nutrition.
38 Thermophilic and thermoacidophilic glycosylation genes and enzymes from Alicyclobacillus acidocaldarius and related organisms, methods US12380450 2009-02-26 US20090263859A1 2009-10-22 David N. Thompson; William A. Apel; Vicki S. Thompson; David W. Reed; Jeffrey A. Lacey
Isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from Alicyclobacillus acidocaldarius are provided. Further provided are methods for glycosylating and/or post-translationally of modifying proteins using isolated and/or purified polypeptides and nucleic acid sequences from Alicyclobacillus acidocaldarius.
39 Transgenic plants with enhanced agronomic traits US12316385 2008-12-11 US20090165165A1 2009-06-25 Savitha Madappa; Pranesh Badami; Dhanalakshmi Ramachandra; S. Sangeetha; K. R. Vidya; Stephen M. Duff; Steve S. He; Linda L. Lutfiyya; T. V. Venkatesh
This invention provides transgenic plant cells with recombinant DNA for expression of proteins that are useful for imparting enhanced agronomic trait(s) to transgenic crop plants. This invention also provides transgenic plants and progeny seed comprising the transgenic plant cells where the plants are selected for having an enhanced trait selected from the group of traits consisting of enhanced water use efficiency, enhanced cold tolerance, increased yield, enhanced nitrogen use efficiency, enhanced seed protein and enhanced seed oil. Also disclosed are methods for manufacturing transgenic seed and plants with enhanced traits.
40 Tumor specific oligosaccharide epitopes and use thereof US10525011 2003-08-20 US20060014672A1 2006-01-19 Jari Natunen; Tero Satomaa; Annamari Heiskanen; Susann Teneberg; Karl-Anders Karlsson
The present invention describes oligosaccharide sequences, which are specifically expressed by human tumors. The present invention is related to a method of determining an oligosaccharide sequence, which comprises a tumor specific terminal N-acetylglucosamine residue, in a biological sample, the presence of said sequence in said sample being an indication of the presence of cancer. The present invention provides antigenic substances comprising said oligosaccharide sequences in a polyvalent form and it further provides diagnostic agents, pharmaceutical compositions and cancer vaccines comprising said oligosaccharide sequences or substances binding to said oligosaccharide sequences. The present invention is also related to methods for the treatment of cancer.
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