| 序号 | 专利名 | 申请号 | 申请日 | 公开（公告）号 | 公开（公告）日 | 发明人 |
|---|---|---|---|---|---|---|
| 1 | 3-芳氧基-3-芳香基-丙胺类化合物及其用途 | CN201980053661.1 | 2019-08-16 | CN112654616B | 2024-03-12 | 王友鑫; 林锦霞; 陈志亮; 蓝文良; 张玲玲; 曲振林 |
| 一类3‑芳氧基‑3‑芳香基‑丙胺类化合物或其药学上可接受的盐，或其前药及其用途，所述化合物具有式I结构,所述的化合物，或其药学上可接受的盐，或其前药对瞬时受体电位通道蛋白(TPR)具有优异的抑制作用，并对瞬时受体电位通道蛋白相关的疾病具有良好的治疗作用。 | ||||||
| 2 | 有机化合物及有机电致发光装置 | CN202310803294.0 | 2023-06-30 | CN116768851A | 2023-09-19 | 何睦; 王湘成; 王鹏 |
| 本发明涉及有机电致发光材料领域，特别是涉及一种有机化合物及有机电致发光装置。所述有机化合物具有如式(1)所示的化学结构： 本发明提供有机化合物、以及包含其的有机电致发光装置，作为有机电致发光器件的电子阻挡层，可以降低器件的工作电压，提高器件的发光效率和使用寿命。 | ||||||
| 3 | 一种Psammaplin A类衍生物及其制备方法和应用 | CN202211403460.X | 2022-11-10 | CN115925675A | 2023-04-07 | 邱培菊; 江涛; 尹瑞娟; 杨金波; 姜玉坤; 付磊 |
| 本发明公开了一种Psammaplin A类衍生物及其制备方法和应用。所述Psammaplin A类衍生物的结构式如式(I)或(Ⅱ)所示： 其中，R1为芳香环、杂环或其取代杂环；R2为H或C1‑5烷基，R3为H或C1‑5烷基；X为H或C1‑5烷基或C3‑5环烷基或芳香环、杂环或其取代杂环；Y为S或Se或Te，Z为S或Se或Te；n＝1～5。本发明的Psammaplin A衍生物具有很好的稳定性，对IDH1/R132H突变酶活具有显著的抑制活性，而对IDH1/WT野生型酶活没有明显影响，且对多种肿瘤细胞株的增殖具有抑制活性，继而达到抑制肿瘤生长的作用，为开发抗肿瘤药物提供了重要参考。 | ||||||
| 4 | 一种吩噁硒/吩噻硒类化合物的合成方法 | CN202010975118.1 | 2020-09-16 | CN112062748A | 2020-12-11 | 周云兵; 李金承; 刘妙昌; 吴华悦 |
| 本发明公开了一种吩噁硒/吩噻硒类化合物的合成方法，该方法经由TMSCN催化的芳基硼酸类底物与硒粉的自由基环化，形成C‑Se键从而构建六或七元吩噁硒/吩噻硒类化合物。该新策略具有无金属参与、无需添加剂促进，广泛的底物范围和良好的官能团兼容性，以高度简洁的方式为各种不同的苯并硒杂环类化合物的制备提供了一个高效和绿色的途径。 | ||||||
| 5 | 3-芳氧基-3-五元杂芳基-丙胺类化合物及其晶型和用途 | CN202080035787.9 | 2020-05-14 | CN114206859A | 2022-03-18 | 王友鑫; 张玲玲; 丁强 |
| 本发明涉及3‑芳氧基‑3‑五元杂芳基‑丙胺类化合物及其晶型和用途。具体地，本发明提供一种化合物，或其药学上可接受的盐、或其前药，所述化合物具有式I结构。本发明所述的化合物，或其药学上可接受的盐、或其前药对瞬时受体电位通道蛋白(TPR)具有优异的抑制作用，并对瞬时受体电位通道蛋白相关的疾病具有良好的治疗作用。 | ||||||
| 6 | 一种吩噁硒/吩噻硒类化合物的合成方法 | CN202010975118.1 | 2020-09-16 | CN112062748B | 2021-07-27 | 周云兵; 李金承; 刘妙昌; 吴华悦 |
| 本发明公开了一种吩噁硒/吩噻硒类化合物的合成方法，该方法经由TMSCN催化的芳基硼酸类底物与硒粉的自由基环化，形成C‑Se键从而构建六或七元吩噁硒/吩噻硒类化合物。该新策略具有无金属参与、无需添加剂促进，广泛的底物范围和良好的官能团兼容性，以高度简洁的方式为各种不同的苯并硒杂环类化合物的制备提供了一个高效和绿色的途径。 | ||||||
| 7 | 3-芳氧基-3-芳香基-丙胺类化合物及其用途 | CN201980053661.1 | 2019-08-16 | CN112654616A | 2021-04-13 | 王友鑫; 林锦霞; 陈志亮; 蓝文良; 张玲玲; 曲振林 |
| 一类3‑芳氧基‑3‑芳香基‑丙胺类化合物或其药学上可接受的盐，或其前药及其用途，所述化合物具有式I结构,所述的化合物，或其药学上可接受的盐，或其前药对瞬时受体电位通道蛋白(TPR)具有优异的抑制作用，并对瞬时受体电位通道蛋白相关的疾病具有良好的治疗作用。 | ||||||
| 8 | ＤＹＲＫを阻害する化合物を含有する医薬組成物 | JP2010521663 | 2009-06-30 | JPWO2010010797A1 | 2012-01-05 | 萩原正敏; 浩司 澁谷; 英理子 大西; 靖 小川; 孝充 細谷; 俊行 平松; 吉田 実代; 実代 吉田 |
| DYRK1A、DYRK1B、及び、DYRK2の少なくとも1つの活性亢進を伴う疾病の治療又は予防のための医薬組成物の提供。DYRK1A、DYRK1B、及び、DYRK2の少なくとも1つの蛋白質リン酸化活性を阻害する化合物を有効成分とする、DYRK1A、DYRK1B、及び、DYRK2の少なくとも1つの活性亢進を伴う疾病の治療又は予防のための医薬組成物。 | ||||||
| 9 | Novel selenium-containing alicyclic compound | JP2007025076 | 2007-02-05 | JP4708373B2 | 2011-06-22 | 光樹 岡崎; 史朗 本間; 博之 森尻; 昌彦 楠本; 守 田中; 芳信 金村 |
| 10 | Tellurium compounds containing high-sensitivity photo thermographic materials and methods of use thereof | JP2002566720 | 2001-12-14 | JP3955821B2 | 2007-08-08 | シー． ウィレット，ブライアン; エル． オペイツ，アンドレア; ジェイムス ジスリング，ヘンリー; エム． ショー，スティーブン; エム． シンプソン，シャロン; シー． リンチ，ドリーン |
| Photothermographic imaging materials having increased photospeed are provided by certain tellurium chemical sensitizers that are added during the formulation of a photothermographic emulsion. These useful chemical sensitizers are represented by the following Structure I or II:wherein X<1 >and X<2 >independently represent halo, OCN, SCN, S(C=S)N(Ra)(Rb), S(C=S)ORa, S(C=S)SRa, S(P=S)(ORa)(ORb)2, S(P=S)(Ra)(Rb), SeCN, TeCN, CN, SRa, ORa, N3, alkyl, aryl, or O(C=O)Ra groups, Ra and Rb are an alkyl, alkenyl, cycloalkyl, heterocycyl, or aryl group, or Ra and Rb taken together can form a 5-, 6- or 7-membered heterocyclic ring, L is a ligand derived from a neutral Lewis base, R' is an alkyl or aryl group, m is 0, 1, 2, or 4, and n is 2 or 4 provided that when m is 0 or 2, n is 2 or 4, and when m is 1 or 4, n is 2, and further provided that multiple X<1>, X<2>, L, Ra, Rb, or R' groups in the molecule can be the same or different groups. | ||||||
| 11 | Tellurium compounds containing high-sensitivity photo thermographic materials and methods of use thereof | JP2002566720 | 2001-12-14 | JP2004519712A | 2004-07-02 | シー． ウィレット，ブライアン; エル． オペイツ，アンドレア; ジェイムス ジスリング，ヘンリー; エム． ショー，スティーブン; エム． シンプソン，シャロン; シー． リンチ，ドリーン |
| 感光度の増加したフォトサーモグラフィ画像形成材料が、フォトサーモグラフィ乳剤の配合の間に添加されたある種のテルル化学増感剤によって与えられる。 これらの有用な化学増感剤は、下記の構造Ｉ又はＩＩ：
【化１】 ［式中、Ｘ １及びＸ ２は、独立に、ハロ、ＯＣＮ、ＳＣＮ、Ｓ（Ｃ＝Ｓ）Ｎ（Ｒ ａ ）（Ｒ ｂ ）、Ｓ（Ｃ＝Ｓ）ＯＲ ａ 、Ｓ（Ｃ＝Ｓ）ＳＲ ａ 、Ｓ（Ｐ＝Ｓ）（ＯＲ ａ ）（ＯＲ ｂ ） ２ 、Ｓ（Ｐ＝Ｓ）（Ｒ ａ ）（Ｒ ｂ ）、ＳｅＣＮ、ＴｅＣＮ、ＣＮ、ＳＲ ａ 、ＯＲ ａ 、Ｎ ３ 、アルキル、アリール又はＯ（Ｃ＝Ｏ）Ｒ ａ基を表し、Ｒ ａ及びＲ ｂは、アルキル、アルケニル、シクロアルキル、複素環式若しくはアリール基であるか、又はＲ ａ及びＲ ｂが一緒になって、５、６若しくは７員複素環式環を形成することができ、Ｌは、中性ルイス塩基から誘導される配位子であり、Ｒ'は、アルキル又はアリール基であり、ｍは０、１、２又は４であり、そしてｎは２又は４であるが、但しｍが０又は２であるとき、ｎは２又は４であり、ｍが１又は４であるとき、ｎは２であり、そして更に、分子内の複数のＸ １ 、Ｘ ２ 、Ｌ、Ｒ ａ 、Ｒ ｂ又はＲ'基は、同じであるか又は異なっていてよい］ により表される。 |
||||||
| 12 | New selenium-containing alicyclic compound | JP30034497 | 1997-10-31 | JPH11130771A | 1999-05-18 | OKAZAKI MITSUKI; MORIJIRI HIROYUKI; TANAKA MAMORU; HONMA SHIRO; KANEMURA YOSHINOBU; KUSUMOTO MASAHIKO |
| PROBLEM TO BE SOLVED: To obtain the subject compound useful as a material having polymerizability, containing a selenium atom in the molecule, capable of answering a strong demand for improvement in refractive index of lens and thinning an edge of lens. SOLUTION: This compound is shown by formula I (Y and Z are each CH2 , Se(selenium) atom or the like; F is SH, acryloyl or the like; (1) is 1-5; (m) is 2-10; (n) is 0-5; (o) is 0-3; (p) is 2-6) such as 2,6-dimercapto methyl-1,4-diselenane. Among these compounds, a dithiol compound organosiloxane obtained by reacting hexadiene with a halogenated selenium of the formula (Se)n Xm such as dichlorodiselenide to give a dihalogenomethyl selenophane of formula II, then converting the halogen atom of the compound of formula II into a mercapto group, for example, by a reaction with thiourea in the presence of a solvent such as water. | ||||||
| 13 | Charge-transfer complex of fulvalene derivative with iodine | JP32889887 | 1987-12-25 | JPH01172382A | 1989-07-07 | TAKAHASHI MITSUO; KAWASAKI YOSHIAKI; KIMURA YASUHIRO |
| NEW MATERIAL:A charge-transfer compelx, expressed by formula I (X1-X8 are sulfur, selenium or tellurium; R1-R4 are 3-10C alkyl, 6-20C aryl, etc., having secondary or tertiary carbon atom) and/or formula II (A1-A4 are H, Cl, alkyl, or I; m1 and m2 are integers of 3-10; n is 2-100) and consisting of 2-15mol. iodine based on 1mol. fulvalene derivative having partially or wholly crosslinked carbon atoms. USE:An active material of positive poles in solid electrolytic cells or batteries. PREPARATION:For example, lumps of sodium are added in small portions to ice-cold methanol and bis(carbonyldithio)tetrathiafulvalene is added thereto and reacted. Benzyl bromide is then dripped and reacted therewith to provide tetrathiabenzyltetrathiafulvalene, which is subsequently mixed with iodine and heated to afford the aimed charge-transfer complex of the fulvalene derivative with the iodine. | ||||||
| 14 | Fulvalene derivative | JP4055386 | 1986-02-26 | JPS6230775A | 1987-02-09 | IGUCHI HIROO; SAITO GUNJI; SEKI KAZUHIKO; MORI TAKEHIKO |
| NEW MATERIAL:A compound expressed by formula I (A is S, Se or Te; R is 3W22C alkyl or alkene). USE: A semiconductor. PREPARATION: CS 2 and Na are refluxed in dimethylformamide (DMF) solvent to give a mixture of compounds expressed by formulas II with III, which is then reacted with zinc chloride and tetrabutylammonium bromide to afford a zinc chelate salt. The resultant zinc chelate salt is then reacted with benzoyl chloride and alcoholate, alkylated and alkenylated to give a compound expressed by formula IV, which is then ketonized with mercuric acetate and reacted with triphenylphosphine, etc., to afford the aimed compound expressed by formula I (A is S), etc. COPYRIGHT: (C)1987,JPO&Japio | ||||||
| 15 | 디올 화합물, 이로부터 얻어진 고분자, 이를 포함하는 고분자 필름 | KR1020180024725 | 2018-02-28 | KR102116041B1 | 2020-05-28 | |
| 16 | 디올 화합물, 이로부터 얻어진 고분자, 이를 포함하는 고분자 필름 | KR1020180024725 | 2018-02-28 | KR1020190103817A | 2019-09-05 | |
| 17 | New selenium-containing alicyclic compound | JP2007025076 | 2007-02-05 | JP2007169291A | 2007-07-05 | OKAZAKI MITSUKI; MORIJIRI HIROYUKI; TANAKA MAMORU; HONMA SHIRO; KANEMURA YOSHINOBU; KUSUMOTO MASAHIKO |
| <P>PROBLEM TO BE SOLVED: To provide a material sufficiently meeting strong requirements to further increase the refractive index of a lens and decrease the edge thickness of the lens. <P>SOLUTION: The selenium-containing alicyclic compound is expressed by formula (1) (Y and Z are each -CH<SB>2</SB>-, =CH-, a C atom, Se atom, S atom, SO<SB>2</SB>, SO or an O atom; the hydrogen atoms of methylene or methine may be substituted with 1-3C lower alkyl, 1-3C lower alkoxy, 1-3C lower alkylthio, an F atom, C atom or Br atom; F is a functional group selected from an SH group, NCO group, NCS group, acryloyl group, methacryloyl group, vinyl group, allyl group, isopropenyl group, epoxy group and thioepoxy group or an alkyl residue composed of the functional group and a ≤10C alkylene group; and l, m, n, o and p are integers of 1-5, 2-10, 0-5, 0-3 and 2-6, respectively). <P>COPYRIGHT: (C)2007,JPO&INPIT | ||||||
| 18 | Novel selenium-containing alicyclic compound | JP30034497 | 1997-10-31 | JP3929143B2 | 2007-06-13 | 光樹 岡崎; 史朗 本間; 博之 森尻; 昌彦 楠本; 守 田中; 芳信 金村 |
| 19 | Silver halide emulsion, silver halide photosensitive material, heat developable photosensitive material and compound | JP2000047160 | 2000-02-24 | JP2001235825A | 2001-08-31 | OSHIYAMA TOMOHIRO; KAGAWA NOBUAKI; IKEMIZU MASARU |
| PROBLEM TO BE SOLVED: To provide a silver halide emulsion having high sensitivity in the visible to ultrared region and less liable to a change of its sensitivity due to a change in exposure conditions and a photographic sensitive material. SOLUTION: The silver halide emulsion contains a compound capable of forming a divalent cation when oxidized. In particular, enthalpy difference (ΔΔH) (value calculated by a semiempirical molecular orbital method using AM1 Hamiltonian) produced between the divalent cation formed by oxidation and its neutral state is >1,700 to <2,000 kJ/mol. | ||||||
| 20 | Huge ring Fushimi ether compound-containing photographic elements | JP18200188 | 1988-07-22 | JP2633634B2 | 1997-07-23 | AASAA HAAMAN HAATSU; ROJAA RII KURAUSU |
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