| 序号 | 专利名 | 申请号 | 申请日 | 公开（公告）号 | 公开（公告）日 | 发明人 |
|---|---|---|---|---|---|---|
| 101 | 약제학적 화합물로 유용한 나알라다제 억제제 및 그의조성물 | KR1020017000232 | 1999-07-02 | KR1020010099586A | 2001-11-09 | 잭슨,폴에프; 맥클린,케이트엠.; 왕,에릭; 슬러셔,바르바라에스.; 라피더스,레나에스.; 메이저,파벨 |
| 본 발명은 N-아세틸화 α-결합 산성 디펩티다제(NAALADase) 억제제, 이 억제제로 구성된 약제학적 조성물 및 나알라다제 효소활성을 억제하기 위한 이것의 사용방법과 이에 따른 효과적인 뉴우런 활성증대, 길항작용 억제, 글루타메이트 이상, 피로, 전립선 질환, 통증 및 당뇨성 신경병 등을 치료하는 것에 관계한다. | ||||||
| 102 | 티올카르바메이트 및 티오시아네이트 화합물의 제조방법 | KR1019990039565 | 1999-09-15 | KR1020000023182A | 2000-04-25 | 기하라가즈아끼; 다무라고로; 나까무라도시유끼; 아이모또도꾸지 |
| PURPOSE: A preparation of thiocarbamate and thiocyanate is provided to form a water soluble inorganic salt as a by-product and easily isolate a lipophilic compound as a desired product after the reaction, thus preventing environmental pollution. CONSTITUTION: The preparation of a compound represented by formula 1 or its salt comprises reacting a compound represented by formula 1 or its salt with hydrocyanic acid or its salt: wherein R¬1 and R¬2 are each independently a hydrocarbon group, or R¬1 and R¬2 form a five membered or six membered hetero ring containing nitrogen with an adjacent nitrogen atom, and wherein the respective symbols represent the same meaning as defined above. | ||||||
| 103 | Ｎ,Ｎ'-디치환-3,3'-디티오디프로피온아미드의 제조방법 및그를 이용한 치환된 3-이소티아졸론의 제조방법 | KR1019970046713 | 1997-09-11 | KR1019990025181A | 1999-04-06 | 김승환; 박정호; 김진만; 한순종; 최기승; 조명호 |
| 3-머캅토프로피온 에스테르를 아민 수용액과 반응시킴으로써 N-치환-3-머캅토프로피온아미드를 제조하고, 상기 N-치환-3-머캅토프로피온아미드를 과산화수소 수용액과 반응시킴으로써 N,N'-디치환-3,3'-디티오디프로피온아미드를 제조하면 짧은 반응시간 내에 고순도의 안정한 N,N'-디치환-3,3'-디티오디프로피온아미드를 고수율로 제조할 수 있으며 반응의 조절이 용이하고 안전성 및 환경적 측면에서 우수할 뿐 아니라, 나아가 치환된 3-이소티아졸론의 제조에 있어서 할로겐화 단계 이전의 탈수 공정을 생략할 수 있고 치환된 3-이소티아졸론을 고수율로 제조할 수 있다. | ||||||
| 104 | 중합체성필름 | KR1019970705672 | 1996-02-15 | KR1019980702275A | 1998-07-15 | 코테스데이비드; 그린필드시몬; 졸리페엠마제인 |
| 본 발명은 (a) 각각의 단량체 또는 올리고머가 (메트)아크릴레이트-에스테르 에폭시 및 비닐 에테르로 이루어진 그룹중에서 선택된 2개 이상의 중합성 작용기를 갖는 하나이상의 상기 단량체 또는 올리고머, 및 (b) 각각의 단량체 또는 올리고머가 (메트)아크릴레이트 에스테르, 에폭시 및 비닐 에테르로 이루어진 그룹중에서 선택된 하나의 중합성 작용기 및 메소제닉 그룹을 갖는 하나이상의 상기 비키랄 액정 단량체 또는 올리고머를 포함하는 혼합물의 공중합에 의해 수득할 수 있는, 망상 중합체를 포함하는 가교결합된 합성 수지 조성물로부터 제조된 광학 이방성 물질로 구성된 중합체성 필름에 관한 것이다. | ||||||
| 105 | 3,6,9-트리옥사운데칸-1,11-비스(3-n-도데실티오프로피오네이트)를 제조하는 방법 | KR1019880002377 | 1988-03-08 | KR1019950013108B1 | 1995-10-24 | 키르크우드스토퍼코트맨; 죠셉앤드루쿠츠코브스키 |
| 내용 없음. | ||||||
| 106 | 사료 첨가제로서 유용한 메티오닌 알카리 금속염용액의 제조방법 | KR1019860010270 | 1986-12-02 | KR100082653B1 | 1995-02-22 | 끌로드질로니에; 르네므와송 |
| 107 | 사료 첨가제로서 유용한 메티오닌 알카리 금속염용액의 제조방법 | KR1019860010270 | 1986-12-02 | KR1019940008921B1 | 1994-09-28 | 끌로드질로니에; 르네므와송 |
| 내용 없음. | ||||||
| 108 | Process for the purification of acrolein | US16520384 | 2019-07-24 | US10556850B1 | 2020-02-11 | Thorsten Merker; Martin Koerfer; Michael Eicker; Bruno Krudewig; Rainer Malzkorn; Haohao Zhu |
| The present invention relates to a process for purifying acrolein. The process includes the steps of a) splitting a liquid feed stream containing acrolein into at least a first liquid stream and a second liquid stream, b) introducing the first liquid stream with a temperature T1 into a distillation column at a point between the top and the bottom of the distillation column, c) introducing the second liquid stream with a temperature T2 into the distillation column at the top of the distillation column, d) withdrawing an overhead vapor stream enriched in acrolein from the distillation column, and e) withdrawing a bottom stream depleted in acrolein. The temperature T2 of the second liquid stream in step c) is lower than the temperature T1 of the first liquid stream in step b). | ||||||
| 109 | Mixed decyl mercaptans compositions and use thereof as mining chemical collectors | US15284809 | 2016-10-04 | US09527090B1 | 2016-12-27 | Jim D. Byers; Michael S. Matson; Jason L. Kreider |
| Disclosed herein is a process for the recovery of a metal from an ore using a collector composition. The process includes contacting the ore with the collector composition. The collector composition can include sulfur-containing compounds comprising (i) mercaptans comprising branched C10 mercaptans compounds selected from the group consisting of 5-methyl-1-mercapto-nonane, 3-propyl-1-mercapto-heptane, 4-ethyl-1-mercapto-octane, 2-butyl-1-mercapto-hexane, 5-methyl-2-mercapto-nonane, 3-propyl-2-mercapto-heptane, 4-ethyl-2-mercapto-octane, 5-methyl-5-mercapto-nonane, and combinations thereof; and (ii) sulfides comprising branched C20 sulfides represented by the structure R1—S—R2, wherein R1 and R2 are each independently a functional group derived from an olefin, wherein the olefin comprises 5-methyl-1-nonene, 3-propyl-1-heptene, 4-ethyl-1-octene, 2-butyl-1-hexene, or combinations thereof. | ||||||
| 110 | Thio compounds and preparing method of the same | US13394730 | 2010-08-31 | US09024073B2 | 2015-05-05 | Hyung Jae Lee; Chang Kyo Shin; Jin Eok Kim |
| Provided are novel thio compounds and a method for preparing the same. More particularly, there is provided a novel thio compound prepared by reacting an alkylation product of p-cresol and dicyclopentadiene with mercaptan and paraformaldehyde. Unlike existing antioxidants such as 2,6-di-t-butyl-4-methylphenol (BHT) being harmful to the human body due to the high volatility, the novel thio compounds of the present invention, which have the low volatility because of their high molecular weight, give no harm to the human body. Further, with excellent performances, they are suitable to replace the existing antioxidants. | ||||||
| 111 | Nanoparticles and nanoparticle compositions | US13640698 | 2011-04-08 | US08790621B2 | 2014-07-29 | Yan Zhao |
| The invention provides multivalent surface-crosslinked micelle (SCM) particles, crosslinked reverse micelle (CRM) particles, and methods of making and using them. The SCM particles can be used, for example, to inhibit a virus or bacteria from binding to a host cell. The inhibition can be used in therapy for the flu, cancer, or AIDS. The CRM particles can be used, for example, to prepare metal nanoparticles or metal alloy nanoparticles, or they can be used in catalytic reactions. | ||||||
| 112 | Immobilized heteropoly acids and the use of the same for electrode stabilization and enhancement | US12122529 | 2008-05-16 | US08753997B2 | 2014-06-17 | Ronald Justin Stanis; Andrew Michael Herring; Mei-Chen Kuo; Jack Richard Ferrell, III |
| The use of fuel cells to produce electricity are known as an environmentally clean and reliable source of energy, and show promise as an automotive power source if the polymer electrolyte membrane fuel cell can be made less expensive, more durable, reduce or eliminate humidification of the reactive gases, and operate at temperatures encountered during automotive operating conditions. The use of an electro-catalyst formed from heteropoly acids immobilized by a conductive material, such as carbon or platinum black, and stabilizing a metallic black with the immobilized conductive material addressed these automotive fuel cell needs. Coating the fuel cell electrode, polymer electrolyte assembly with a nano-particle catalyst derived from a heteropoly acid provided anodic carbon monoxide tolerance at anodic overpotentials and an active cathodic oxygen reduction. The heteropoly acids can also function as supercapacitor electrode films. | ||||||
| 113 | Substituted phenylsulfur trifluoride and other like fluorinating agents | US12886286 | 2010-09-20 | US08710270B2 | 2014-04-29 | Teruo Umemoto |
| Novel substituted phenylsulfur trifluorides that act as fluorinating agents are disclosed. Also disclosed are methods for their preparation and methods for their use in introducing one or more fluorine atoms into target substrate compounds. Finally, various intermediate compounds for use in preparing substituted phenylsulfur trifluorides are provided. | ||||||
| 114 | Bis-aromatic anticancer agents | US12936608 | 2009-04-06 | US08686190B2 | 2014-04-01 | Ahmad Safavy |
| Treatment of cancer includes administering a compound of formula (I) to a subject. In particular, treatment of colorectal cancer is described. | ||||||
| 115 | Derivatisation of biological molecules | US12527233 | 2008-02-12 | US08575397B2 | 2013-11-05 | Stephen James Brocchini; Antony Robert Godwin; Yiqing Tang; Andrew Lennard Lewis |
| The present disclosure relates to a new polymerization process in which ethylenically unsaturated monomers are polymerised by a living radical polymerization process in the presence of an initiator and a catalyst. Polymers produced by this new process are also thought to be novel and may be used to derivatise biological molecules to improve their efficacy as therapeutic treatments. A preferred polymer is of formula The polymers are particularly suitable for derivatising proteins, such as interferon-α. | ||||||
| 116 | 3-aminocarbonyl-substituted benzoylcyclohexanediones and their use as herbicides | US13029373 | 2011-02-17 | US08557741B2 | 2013-10-15 | Chieko Ueno; Simon Dörner-Rieping; Andreas Van Almsick; Christopher Hugh Rosinger; Jan Dittgen; Dieter Feucht; Isolde Häuser-Hahn |
| What is described are 3-aminocarbonyl-substituted benzoylcyclohexanediones of the formula (I) as herbicides. In this formula (I), R1 to R5 are radicals such as hydrogen, organic radicals such as alkyl, and other radicals such as halogen. X is alkylene. | ||||||
| 117 | Process for the preparation of 3-alkylsulfinylbenzoyl derivatives | US13335662 | 2011-12-22 | US08455657B2 | 2013-06-04 | Mark James Ford; Jan Peter Schmidt; Helmut Kohlhepp |
| A process is described for the preparation of 3-alkylsulfinylbenzoyl derivatives of the formula (IIIa) by reaction of 3-alkylsulfinylbenzoic acids of the formula (Ib) with compounds of the formula (II) in the presence of a chlorinating agent and a base. In the formulae specified above, Y is a radical such as pyrazolyl and cyclohexanedionyl. R1, R2 and R3 are radicals such as halogen, nitro, cyano and alkyl. | ||||||
| 118 | S-perfluoroalkyl substituted hydroxybenzylthioethers and derivatives as surface modifiers | US12308036 | 2007-06-04 | US08246859B2 | 2012-08-21 | Michèle Gerster; Manuel Mihalic |
| The invention describes a process for reducing the surface energy of organic materials such as for example increasing the oil and water repellency and stain release of organic materials, which comprises treating the organic material with at least a compound of the formula I wherein the general symbols are as defined in claim 1; especially wherein at least one of the radicals R2, R3 or R4 is —CH(R11)—S(O)p—R12; R11 is hydrogen, C1-C8alkyl, unsubstituted or with C1-C4alkyl substituted phenyl; R12 is a monovalent perfluorinated alkyl or alkenyl, linear or branched organic radical having four to twenty fully fluorinated carbon atoms, and p is 0, 1 or 2. | ||||||
| 119 | Process for producing 2-hydroxy-4-(methlthio)butyrate compounds and intermediates thereof | US12309470 | 2007-07-20 | US08071805B2 | 2011-12-06 | Koji Hagiya |
| A process for producing a 2-hydroxy-4-(methylthio)butyrate compound represented by the formula (2): wherein A is a hydrogen atom or a group represented by R—CH2—, wherein R is a hydrogen atom or an alkyl group, which comprises the step of: reacting 4-(methylthio)-2-oxo-1-butanol with oxygen and a compound represented by the formula (1): A-OH (1) wherein A is as defined above, in the presence of a copper compound. | ||||||
| 120 | Functional group-selective hydrogenation catalyst and functional group-selective hydrogenation method | US11565844 | 2006-12-01 | US07795166B2 | 2010-09-14 | Hironao Sajiki; Tomohiro Maegawa; Kosaku Hirota |
| A functional group-selective hydrogenation catalyst is provided, which is capable of selectively hydrogenating an aliphatic carbon-carbon double bond, aliphatic carbon-carbon triple bond, aromatic formyl group or aromatic nitro group contained in an organic compound. The catalyst includes a carrier, and palladium and an organic sulfur compound supported jointly thereon. | ||||||
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