141 |
JPS59501982A - |
JP50301083 |
1983-09-23 |
JPS59501982A |
1984-11-29 |
|
|
142 |
Plant growth regulator |
JP2968884 |
1984-02-21 |
JPS59157067A |
1984-09-06 |
HANSU GEORUKU SHIYUMITSUTO; KURAUSU RIYURUSEN; KARURUFURIITO BEDEMAIYAA |
|
143 |
Diffusion transfer photographic film unit |
JP25247083 |
1983-12-28 |
JPS59136732A |
1984-08-06 |
ABINATSUSHIYU SHII META |
|
144 |
Propionic acid derivative and manufacture |
JP24235483 |
1983-12-23 |
JPS59130236A |
1984-07-26 |
SEIKE KOUICHI; UBE PURIISUNITSUTSU; HANSUUYOTSUHEMU RIIBERU; RUUTOUITSUHI OIE; ROBERUTO AARU SHIYUMITSUTO |
|
145 |
Enantiomer of propionic acid derivative and manufacture |
JP24235383 |
1983-12-23 |
JPS59130235A |
1984-07-26 |
SEIKE KOUICHI; UBE PURIISUNITSUTSU; HANSUUYOTSUHEMU RIIBERU; RUUTOUITSUHI OIE; ROBERUTO AARU SHIYUMITSUTO |
|
146 |
Leucotriene antagonist |
JP18099883 |
1983-09-30 |
JPS5993043A |
1984-05-29 |
PATORISU SHII BERANJIYAA; REJIYAN FUOOTEIN; IBUAN GIYUINDON; JIYOSHIYUA ROKATSUCHI; KURISUCHIYAN YOAKIMU |
|
147 |
Benzhydrylsulfinylacetamide derivative, manufacture and central nervous system therapy |
JP9879883 |
1983-06-04 |
JPS591459A |
1984-01-06 |
RUI RAFUON |
|
148 |
Polyanionic compound, manufacture and composition |
JP1728983 |
1983-02-04 |
JPS58145795A |
1983-08-30 |
GIYUI BANRERUBERUGE; ANRI SEBATSUGU |
|
149 |
Manufacture of alpha,alpha-difluoroalkoxy or alpha,alpha-difluoroalkylthiophenylsulfone |
JP11088082 |
1982-06-29 |
JPS58124760A |
1983-07-25 |
MISHIERU DEBOWA |
|
150 |
Aminophenol derivative, its preparation and remedy containing the same |
JP20974081 |
1981-12-28 |
JPS58113152A |
1983-07-05 |
WAKATSUKA HIROHISA; MOURI TETSUYA; HASHIMOTO SHINSUKE |
NEW MATERIAL:A compound of formulaI[R is formula II(Z is thio, sulfinyl; n is 1, 2, 3; R
1 is H, alkyl, halogen, hydroxyl), formula III (R
2 is H, alkyl, halogen; m is 1, 2), formula IV and formula V].
EXAMPLE: 2-Amino-4-phenylthiophenol.
USE: A preventive of or remedy for allergic tracheitis, bronchitis, pneumonopathy, a variety of inflammations and a variety of inflammation caused by prostaglandins.
PREPARATION: The selective reduction of the nitro group in the 2-position of the compound of formulaIis conducted with a hydrogen gas in the presence of a catalyst such as Ni, Pt or Pd on carbon or by using Fe, Zn, Sn or SnCl
2 and hydrochloric acid to give the compound of formulaIwith NH
2 group.
COPYRIGHT: (C)1983,JPO&Japio |
151 |
JPS5757015B2 - |
JP13975878 |
1978-11-13 |
JPS5757015B2 |
1982-12-02 |
TOOMASU HENRII ORUZAISU; CHAARUZU AAMON HAABAATO; MAIKERU ROSU JONSON; ROORENSU SHAAMAN MERUBIN JUNIAA |
Compounds of the formula <IMAGE> <IMAGE> wherein R1 is hydrogen, benzyl, benzoyl, alkanoyl of 1 to 5 carbon atoms or -CO-(CH2)p-NR'R'' wherein p is 0 or an integer from 1 to 4; each of R' and R'' when taken individually is hydrogen or alkyl of 1 to 4 carbon atoms; R' and R'' when taken together with the nitrogen to which they are attached form a 5- or 6-membered heterocyclic ring selected from piperidino, pyrollo, pyrrolidino, morpholino and N-alkylpiperazino having from 1 to 4 carbon atoms in the alkyl group; R2 is selected from hydrogen, alkanoyl of 1 to 6 carbon atoms and benzoyl; R3 is selected from hydrogen, methyl and ethyl; R4 is selected from hydrogen, alkyl of 1 to 6 carbon atoms and benzyl; Z is selected from: (a) alkylene having from one to nine carbon atoms; (b) -(alk1)m-X-(alk2)n- wherein each of (alk1) and (alk2) is alkylene having from 1 to 9 carbon atoms, with the proviso that the summation of carbon atoms in (alk1) plus (alk2) is not greater than 9; m and n are each 0 or 1; X is selected from O, S, SO, and SO2; and W is selected from hydrogen, methyl, pyridyl, piperidyl, phenyl, monochlorophenyl, monofluorophenyl and <IMAGE> wherein W1 is selected from hydrogen, phenyl, monochlorophenyl and monofluorophenyl; a is an integer from 1 to 5 and b is 0 or an integer from 1 to 4, with the proviso that the sum of a and b is not greater than 5. Compounds I and II are useful as analgesics. Compound III is useful as an intermediate for the preparation of Compounds I and II. Intermediates for the preparation of I, II and III are disclosed. A process for the use of compounds I and II to produce analgesia is also described. |
152 |
Salt of 5-fluoro-2-methyl-1-(p- (methylsulfinyl)benzylidene)indene-3-acetic acid |
JP4703282 |
1982-03-23 |
JPS57167958A |
1982-10-16 |
KARURO MIRANI; JIOBANNI MARIA KARUMINAACHI; ATSUCHIRIO SOBEERA |
|
153 |
JPS5736899B2 - |
JP1823977 |
1977-02-23 |
JPS5736899B2 |
1982-08-06 |
|
|
154 |
JPS5727107B1 - |
JP10151170 |
1970-11-19 |
JPS5727107B1 |
1982-06-08 |
|
|
155 |
4-substituted 3,3-dimethyl-butane-2-ones and manufacture |
JP8583581 |
1981-06-05 |
JPS5726636A |
1982-02-12 |
BUORUFUGANGU KUREEMAA; HANSUURUUTOUITSUHI ERUBE |
|
156 |
JPS5640152B2 - |
JP14229777 |
1977-11-29 |
JPS5640152B2 |
1981-09-18 |
|
|
157 |
JPS5640151B1 - |
JP769372 |
1972-01-21 |
JPS5640151B1 |
1981-09-18 |
|
|
158 |
JPS5639281B2 - |
JP11037475 |
1975-09-11 |
JPS5639281B2 |
1981-09-11 |
|
|
159 |
JPS5638587B1 - |
JP630078 |
1978-01-25 |
JPS5638587B1 |
1981-09-08 |
|
|
160 |
JPS5636163B2 - |
JP9076074 |
1974-08-09 |
JPS5636163B2 |
1981-08-22 |
|
|