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Fermentative preparation of tryptophan derivatives

阅读:126发布:2023-10-25

专利汇可以提供Fermentative preparation of tryptophan derivatives专利检索,专利查询,专利分析的服务。并且The present invention relates to a process for continuous fermentative preparation of L-tryptophan and derivatives thereof. The process comprises culturing the microorganism Candida humicola under aerobic conditions in a continuously supplied nutrient substrate with a separate continuous supply of the corresponding indole derivative. The present invention has now made it possible to carry out a continuous process that has the advantage to give L-tryptophan or a derivative thereof at such a low price that it may be used as an additive to food stuffs and feed stuffs.,下面是Fermentative preparation of tryptophan derivatives专利的具体信息内容。

1. A PROCESS OF CONTINUOUS FERMENTATIVE PREPARATION OF LTRYPTOPHAN DERIVATIVES HAVING THE GENERAL FORMULA:
2. The process of claim 1 wherein niacin is added to the nutrient substrate.
3. The process of claim 2 wherein the niacin is added in a concentration of about 0.05 to 0.5 grams per liter of the substrate.
4. The process of claim 2 wherein glycine is added to the nutrient substrate.
5. The process of claim 4 wherein the glycine is added in an amount of about 1 to 10 grams per liter of the substrate.
6. The process of claim 5 wherein iron is added to the nutrient substrate.
7. The process of claim 1 wherein glycine is added to the nutrient substrate.
8. The process of claim 1 wherein iron is added to the nutrient substrate.
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