专利检索_ .专门适用于筛选化合物库和鉴别库成员二者的成套装置专利检索_ .专门适用于筛选化合物库和鉴别库成员二者的成套装置专利检索查询

序号	专利名	申请号	申请日	公开（公告）号	公开（公告）日	发明人
41	Integrated systems and methods for diversity generation and screening	US10154939	2002-05-23	US20030054384A1	2003-03-20	Steven H. Bass; S. Christopher Davis; Phillip A. Patten; Matthew Tobin; Jeremy Minshull; Mark Welch; Claus Gustafsson; Brian Carr; Stephane Jenne; Sun Ai Raillard; Andreas Crameri; Willem P.C. Stemmer; Robin Emig; Pascal Longschamp; Stanley Goldman; Lorraine J. Giver; Joseph A. Affholter
Integrated systems and methods for diversity generation and screening are provided. The systems use common fluid and array handling components to provide nucleic acid diversification, transcription, translation, product screening and subsequent diversification reactions.
42	고순도 뉴클레오타이드의 대량 생산방법	KR1020120080601	2012-07-24	KR101471246B1	2014-12-10	권성훈; 김효기; 이호원; 김성식; 류태훈
고체지지체상에존재하는올리고뉴클레오타이드들의복제라이브러리를갖는염기서열분석기판을제공하는단계; 상기복제라이브러리를시퀀싱하는단계; 상기염기서열분석기판상의상기고체지지체의실측위치정보를얻는단계; 상기시퀀싱의결과로주어지는상기고체지지체로부터발생한신호의픽셀정보와상기실측위치정보를맵핑하는단계; 상기맵핑한결과를이용하여원하는염기서열을갖는상기고체지지체를상기염기서열분석기판으로부터추출하는단계; 및상기추출된상기고체지지체상의올리고뉴클레오타이드를증폭하여대량으로복제하는단계를포함하는고순도뉴클레오타이드의대량생산방법이제공된다.
43	고순도 뉴클레오타이드의 대량 생산방법	KR1020120080601	2012-07-24	KR1020130046342A	2013-05-07	권성훈; 김효기; 이호원; 김성식; 류태훈
PURPOSE: A method for producing a large amount of high purity nucleotides is provided to quickly and accurately isolated microbeads with a predetermined base sequence and to amplify in a usable amount. CONSTITUTION: A method for producing a large amount of high purity nucleotides comprises: a step of providing a sequencing substrate with a replication library of oligonucleotides on a solid support(S110); a step of sequencing the replication library(S120); a step of obtaining measured location information of the solid support on the sequencing substrate(S130); a step of mapping pixel information and measured location information generated from the solid support(S140); a step of isolating a solid support with desired base sequence from the sequencing substrate using the mapping result(S150); and a step of amplifying the oligonucleotide of the isolated solid support(S160). [Reference numerals] (AA) Start; (BB) End; (S110) Provide a sequencing analysis substrate with a replication library of oligos on a solid support; (S120) Sequence the replication library; (S130) Obtain the actual location information of the solid support; (S140) Map pixel information and the actual location information; (S150) Extract the solid support using a mapping result; (S160) Massively replicate by amplifying the oligos of the extracted solid support
44	공간적으로 엔코딩된 생물학적 검정	KR1020127029015	2011-04-05	KR101866401B1	2018-06-11	체,마크,에스.
본발명은공간적으로엔코딩된생물학적검정에사용하기위한검정및 검정시스템을제공한다. 본발명은시약이규정된공간패턴내에생물학적샘플로제공되는높은수준의다중화가가능한검정; 공간패턴에따라시약의조절된전달이가능한장비; 및본질적으로디지털인판독값을제공하는디코딩도식을포함하는검정시스템을제공한다.
45	고순도 뉴클레오타이드의 대량 생산방법	KR1020120114103	2012-10-15	KR101509293B1	2015-04-07	권성훈; 김효기; 이호원; 김성식; 류태훈
고체지지체상에존재하는올리고뉴클레오타이드들의복제라이브러리를갖는염기서열분석기판을제공하는단계; 상기복제라이브러리를시퀀싱하는단계; 상기염기서열분석기판상의상기고체지지체의실측위치정보를얻는단계; 상기시퀀싱의결과로주어지는상기고체지지체로부터발생한신호의픽셀정보와상기실측위치정보를맵핑하는단계; 상기맵핑한결과를이용하여원하는염기서열을갖는상기고체지지체를상기염기서열분석기판으로부터추출하는단계; 및상기추출된상기고체지지체상의올리고뉴클레오타이드를증폭하여대량으로복제하는단계를포함하는고순도뉴클레오타이드의대량생산방법이제공된다.
46	공간적으로 엔코딩된 생물학적 검정	KR1020127029015	2011-04-05	KR1020130100051A	2013-09-09	체,마크,에스.
본 발명은 공간적으로 엔코딩된 생물학적 검정에 사용하기 위한 검정 및 검정 시스템을 제공한다. 본 발명은 시약이 규정된 공간 패턴 내에 생물학적 샘플로 제공되는 높은 수준의 다중화가 가능한 검정; 공간 패턴에 따라 시약의 조절된 전달이 가능한 장비; 및 본질적으로 디지털인 판독값을 제공하는 디코딩 도식을 포함하는 검정 시스템을 제공한다.
47	고순도 뉴클레오타이드의 대량 생산방법	KR1020120114103	2012-10-15	KR1020130046356A	2013-05-07	권성훈; 김효기; 이호원; 김성식; 류태훈
PURPOSE: A mass production method of a high purity nucleotide is provided to quickly and accurately isolate a microbead with a predetermined sequence and to amplify the sequence. CONSTITUTION: A mass production method of a high purity nucleotide comprises: a step of providing a sequencing substrate with a replication library of oligonucleotides existing on a solid support(S110); a step of sequencing the replication library(S120); a step of obtaining measured location information of the solid support(S130); a step of mapping pixel information of a signal generated from the solid support and the measured location information(S140); a step of extracting a desired sequence from the sequencing substrate using the mapping result(S150); and a step of amplifying a large amount of oligonucleotides on the solid support(S160). [Reference numerals] (AA) Start; (BB) End; (S110) Provide a sequencing analysis substrate with a replication library of oligos on a solid support; (S120) Sequence the replication library; (S130) Obtain the actual location information of the solid support; (S140) Map pixel information and the actual location information; (S150) Extract the solid support using a mapping result; (S160) Massively replicate by amplifying the oligos of the extracted solid support
48	ARRAYS AND METHODS FOR GUIDED CELL PATTERNING	PCT/US2008050307	2008-01-04	WO2008086228A3	2009-12-30	ZHANG MIQIN; VEISEH MANDANA
Guided cell patterning arrays for single cell patterning, methods for making the arrays, and methods for using the arrays.
49	HIGH THROUGHPUT LIGAND BINDING ASSAYS AND REAGENTS	PCT/US2007074322	2007-07-25	WO2008091378A3	2008-10-09	WOODBURY NEAL
The present invention provides methods, compositions, and computer readable storage media for multiplex detection of ligand binding.
50	INTEGRATED SYSTEMS AND METHODS FOR DIVERSITY GENERATION AND SCREENING	PCT/US0101056	2001-01-10	WO0151663A3	2002-06-13	BASS STEVEN H; DAVIS S CHRISTOPHER; PATTEN PHILLIP A; TOBIN MATTHEW; MINSHULL JEREMY; WELCH MARK; GUSTAFSSON CLAES; CARR BRIAN; JENNE STEPHANE; RAILLARD SUN AI; CRAMERI ANDREAS; STEMMER WILLEM P C; EMIG ROBIN; LONGCHAMP PASCAL; GOLDMAN STANLEY; GIVER LORRAINE J; AFFHOLTER JOSEPH A
Integrated systems and methods for diversity generation and screening are provided. The systems use common fluid and array handling components to provide nucleic acid diversification, transcription, translation, product screening and subsequent diversification reactions.

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