| 序号 | 专利名 | 申请号 | 申请日 | 公开（公告）号 | 公开（公告）日 | 发明人 |
|---|---|---|---|---|---|---|
| 1 | Peptides and Methods for Detecting MPO-ANCA | US14370498 | 2013-01-03 | US20150017665A1 | 2015-01-15 | Ronald Falk; Aleeza Roth |
| The present invention relates to disorder-specific epitopes recognized by myeloperoxidase-anti-neutrophil cytoplasmic autoantibodies and the use of polypeptides comprising the epitopes in methods of diagnosing and monitoring autoimmune disorders associated with the autoantibodies. | ||||||
| 2 | Purified myeloblastin, nucleic acid molecule encoding same, and uses thereof | US455614 | 1989-12-22 | US5180819A | 1993-01-19 | Yvon Cayre |
| This invention provides an isolated nucleic acid molecule encoding human myeloblastin, a nucleic acid probe for detecting myeloblastin, and an antisense oligodeoxynucleotide complementary to myeloblastin mRNA. The invention also provides antibodies directed to myeloblastin, and purified myeloblastin. The invention further provides a pharmaceutical composition to inhibit proliferation and induce differentiation of leukemia cells, a myeloblastin inhibitor, and a factor suppressing myeloblastin expression. The invention provides methods for identifying leukemia cells which express different quantities of myeloblastin, treating leukemia, and for preparing purified myeloblastin. | ||||||
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