| 序号 | 专利名 | 申请号 | 申请日 | 公开（公告）号 | 公开（公告）日 | 发明人 |
|---|---|---|---|---|---|---|
| 1 | 用于治疗口炎性腹泻的组合物和方法 | CN201480050953.7 | 2014-08-13 | CN105555300A | 2016-05-04 | J·B·西格尔; D·贝克; I·S·普尔兹 |
| 本发明提供了用于治疗口炎性腹泻的组合物和方法。 | ||||||
| 2 | Sugar-chain modified yeast and method for producing glycoprotein using the same | US13409558 | 2012-03-01 | US09017969B2 | 2015-04-28 | Hiroko Abe; Kazuya Tomimoto; Yasuko Fujita; Tomoko Iwaki; Yasunori Chiba; Yoshihiro Nakajima; Kenichi Nakayama; Masatoshi Kataoka; Shouki Yatsushiro; Shohei Yamamura |
| The present invention provides: genetically modified yeasts such as mutant yeasts having an ability to produce N-linked sugar chains of Man5GlcNAc2 and a decreased ability to produce O-linked sugar chains, mutant yeasts having an ability to produce N-linked sugar chains of Man5GlcNAc2 and further having an ability to produce N-linked sugar chains of GlcNAc1Man5GlcNAc2, and mutant yeasts having an increased ability to produce and secrete proteins and an ability to produce N-linked sugar chains of Man5GlcNAc2; and a method for producing glycoproteins using them. | ||||||
| 3 | Compositions and Methods for Treating Celiac Sprue Disease | US14911630 | 2014-08-13 | US20160194621A1 | 2016-07-07 | Justin Bloomfield SIEGEL; David BAKER; Ingrid Swanson PULTZ |
| The invention provides compositions and methods for treating celiac sprue. | ||||||
| 4 | SUGAR-CHAIN MODIFIED YEAST AND METHOD FOR PRODUCING GLYCOPROTEIN USING THE SAME | US13409558 | 2012-03-01 | US20130171692A1 | 2013-07-04 | Hiroke Abe; Kazuya Tomimoto; Yasuko Fujita; Tomoko Iwaki; Yasunori Chiba; Yoshihiro Nakajima; Kenichi Nakayama; Masatoshi Kataoka; Shouki Yatsushiro; Shohei Yamamura |
| The present invention provides: genetically modified yeasts such as mutant yeasts having an ability to produce N-linked sugar chains of Man5GlcNAc2 and a decreased ability to produce O-linked sugar chains, mutant yeasts having an ability to produce N-linked sugar chains of Man5GlcNAc2 and further having an ability to produce N-linked sugar chains of GlcNAc1Man5GlcNAc2, and mutant yeasts having an increased ability to produce and secrete proteins and an ability to produce N-linked sugar chains of Man5GlcNAc2; and a method for producing glycoproteins using them. | ||||||
| 5 | 糖鎖改変酵母及びそれを用いた糖タンパク質の製造方法 | JP2011289411 | 2011-12-28 | JP5885191B2 | 2016-03-15 | 安部 博子; 冨本 和也; 藤田 康子; 岩城 知子; 千葉 靖典; 中島 芳浩; 仲山 賢一; 片岡 正俊; 八代 聖基; 山村 昌平 |
| 6 | セリアックスプルー病を処置するための組成物および方法 | JP2016534809 | 2014-08-13 | JP2016528253A | 2016-09-15 | シーゲル，ジャスティン，ブルームフィールド; ベイカー，デイビット; パルツ，イングリッド，スワンソン |
| 本発明は、セリアックスプルーを処置するための組成物および方法を提供する。【選択図】なし | ||||||
| 7 | Sugar chain-modified yeast and method for producing glycoprotein therewith | JP2011289411 | 2011-12-28 | JP2012152211A | 2012-08-16 | ABE HIROKO; TOMIMOTO KAZUYA; FUJITA YASUKO; IWAKI TOMOKO; CHIBA YASUNORI; NAKAJIMA YOSHIHIRO; NAKAYAMA KENICHI; KATAOKA MASATOSHI; YASHIRO KIYOMOTO; YAMAMURA SHOHEI |
| PROBLEM TO BE SOLVED: To provide a yeast which can inhibit the O-glycosylation of a host, hold a sufficient proliferation ability, and synthesize a mammal type N-bound type sugar chain.SOLUTION: There is provided the mutant yeast which lacks the functions of protein-O-mannosyl transferase gene, α-1,6-mannosyl transferase gene, α-1,3-mannosyl transferase gene, and mannose-1-phosphate addition control gene, has α-1,2-mannosidase I gene transferred thereto, and has an N-bound type sugar chain-producing ability, and has a lowered ability for producing O-bound type sugar chain. | ||||||
| 8 | COMPOSITIONS FOR TREATING CELIAC SPRUE DISEASE | EP14756186.4 | 2014-08-13 | EP3033100B1 | 2018-10-03 | SIEGEL, Justin Bloomfield; BAKER, David; PULTZ, Ingrid Swanson |
| The invention provides compositions and methods for treating celiac sprue. | ||||||
| 9 | COMPOSITIONS AND METHODS FOR TREATING CELIAC SPRUE DISEASE | EP14756186.4 | 2014-08-13 | EP3033100A1 | 2016-06-22 | SIEGEL, Justin Bloomfield; BAKER, David; PULTZ, Ingrid Swanson |
| The invention provides compositions and methods for treating celiac sprue. | ||||||
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