| 序号 | 专利名 | 申请号 | 申请日 | 公开（公告）号 | 公开（公告）日 | 发明人 |
|---|---|---|---|---|---|---|
| 1 | 一种新的多肽——甲酰胺基嘧啶－DNA糖基化酶37和编码这种多肽的多核苷酸 | CN00111838.2 | 2000-03-02 | CN1311323A | 2001-09-05 | 毛裕民; 谢毅 |
| 本发明公开了一种新的多肽——甲酰胺基嘧啶－DNA糖基化酶37,编码此多肽的多核苷酸和经DNA重组技术产生这种多肽的方法。本发明还公开了此多肽用于治疗多种疾病的方法,如恶性肿瘤,血液病,HIV感染和免疫性疾病和各类炎症等。本发明还公开了抗此多肽的拮抗剂及其治疗作用。本发明还公开了编码这种新的甲酰胺基嘧啶－DNA糖基化酶37的多核苷酸的用途。 | ||||||
| 2 | TREATMENT OF DISEASE CONDITIONS VIA ADMINISTRATION OF DNA REPAIR ENZYME | US14518458 | 2014-10-20 | US20150118217A1 | 2015-04-30 | Glenn Wilson; Susan Ledoux; Mikhail Alexeyev; Inna Shokolenko; Mark N. Gillespie |
| The present invention is directed to compositions and methods of preserving viability of islets of Langerhans for transplantation, and treating various disease and other abnormal or pathological conditions, including inflammatory bowel disease, ischemic heart disease, acute lung injury, acute respiratory distress syndrome and radiation-induced brain injury, with DNA repair enzymes that are directed to the mitochondria. | ||||||
| 3 | Method for Reducing Sequencing Errors Caused by DNA Fragmentation | US15414260 | 2017-01-24 | US20180051341A1 | 2018-02-22 | Thomas C. Evans, Jr.; Laurence Ettwiller; Lixin Chen; Pingfang Liu |
| Provided herein, among other things, is a method for reducing sequencing errors caused by mechanical DNA fragmentation. In some embodiments, this method may comprise: (a) obtaining a DNA sample; (b) mechanically fragmenting the DNA sample to produce a template; (c) treating the fragmented DNA with a plurality of DNA repair enzymes; and (d) obtaining a sequence of the fragmented DNA. The treatment step (c) reduces the number of fragmentation induced errors. | ||||||
| 4 | Treatment of disease conditions via administration of DNA repair enzyme | US14518458 | 2014-10-20 | US09404102B2 | 2016-08-02 | Glenn Wilson; Susan Ledoux; Mikhail Alexeyev; Inna Shokolenko; Mark N. Gillespie |
| The present invention is directed to compositions and methods of preserving viability of islets of Langerhans for transplantation, and treating various disease and other abnormal or pathological conditions, including inflammatory bowel disease, ischemic heart disease, acute lung injury, acute respiratory distress syndrome and radiation-induced brain injury, with DNA repair enzymes that are directed to the mitochondria. | ||||||
| 5 | Treatment of disease conditions via administration of DNA repair enzyme | US12866540 | 2009-02-09 | US08865160B2 | 2014-10-21 | Glenn Wilson; Susan Ledoux; Mikhail Alexeyev; Inna Shokolenko; Mark N. Gillespie |
| The present invention is directed to compositions and methods of preserving viability of islets of Langerhans for transplantation, and treating various diseases and other abnormal or pathological conditions, including inflammatory bowel disease, ischemic heart disease, acute lung injury, acute respiratory distress syndrome and radiation-induced brain injury, with DNA repair enzymes that are directed to the mitochondria. | ||||||
| 6 | TREATMENT OF DISEASE CONDITIONS VIA ADMINISTRATION OF DNA REPAIR ENZYME | US12866540 | 2009-02-09 | US20110110908A1 | 2011-05-12 | Glenn Wilson; Susan Ledoux; Mikhail Alexeyev; Inna Shokolenko; Mark N. Gillespie |
| The present invention is directed to compositions and methods of preserving viability of islets of Langerhans for transplantation, and treating various diseases and other abnormal or pathological conditions, including inflammatory bowel disease, ischemic heart disease, acute lung injury, acute respiratory distress syndrome and radiation-induced brain injury, with DNA repair enzymes that are directed to the mitochondria. | ||||||
| 7 | TREATMENT OF DISEASE CONDITIONS VIA ADMINISTRATION OF DNA REPAIR ENZYME | PCT/US2009000889 | 2009-02-09 | WO2009099679A2 | 2009-08-13 | WILSON GLENN; LEDOUX SUSAN; ALEXEYER MIKHAIL; SHOKOLENKO INNA; GILLESPIE MARK N |
| The present invention is directed to compositions and methods of preserving viability of islets of Langerhans for transplantation, and treating various diseases and other abnormal or pathological conditions, including inflammatory bowel disease, ischemic heart disease, acute lung injury, acute respiratory distress syndrome and radiation- induced brain injury, with DNA repair enzymes that are directed to the mitochondria. | ||||||
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