| 序号 | 专利名 | 申请号 | 申请日 | 公开（公告）号 | 公开（公告）日 | 发明人 |
|---|---|---|---|---|---|---|
| 1 | METHODS FOR INCREASING CAS9-MEDIATED ENGINEERING EFFICIENCY | US14836753 | 2015-08-26 | US20160257973A1 | 2016-09-08 | Peter Sean Cameron; Rachel E. Haurwitz; Andrew P. May; Christopher H. Nye; Megan van Overbeek |
| Methods for use with Type II CRISPR-Cas9 systems for increasing Cas9-mediated genome engineering efficiency are disclosed. The methods can be used to decrease the number of off-target nucleic acid double-stranded breaks and/or to enhance homology-directed repair of a cleaved target nucleic acid. | ||||||
| 2 | 布地の処理方法 | JP2017556551 | 2016-04-27 | JP2018517803A | 2018-07-05 | ニール、ジョセフ、ラント; レベッカ、ルイーズ、ウッド; ジェレミー、ロバート、マルセル、グメル |
| 布地を処理する方法であって、カチオン性柔軟化化合物、シリコーン柔軟化化合物、パラフィン、分散性ポリオレフィン、ワックス、及びこれらの混合物からなる群から選択される布地ケア成分を含む水性液に当該布地を接触させる工程と、ヌクレアーゼ酵素、好ましくは、デオキシリボヌクレアーゼ又はリボヌクレアーゼ酵素を含む水性液に当該布地を接触させる工程と、を含む、方法。水性液は、洗浄又は処理組成物を水に添加することによって提供され得る。好ましくは、組成物は、界面活性剤を含み、洗浄液は、0.05〜4g/Lの界面活性剤を含む。 | ||||||
| 3 | METHOD OF TREATING A FABRIC | EP16167256.3 | 2016-04-27 | EP3088503A1 | 2016-11-02 | LANT, Neil Joseph; WOOD, Rebecca Louise; GUMMEL, Jeremie Robert Marcel |
A method of treating a fabric, comprising contacting the fabric with an aqueous liquor comprising a fabric care component selected from the group consisting of cationic softening-compounds, silicone softening-compounds, paraffins, dispersible polyolefins, waxes and mixtures thereof; and contacting the fabric with an aqueous liquor comprising a nuclease enzyme, preferably a deoxyribonuclease or ribonuclease enzyme. The aqueous liquor may be provided by adding a cleaning or treatment composition to water. Preferably the composition |
||||||
| 4 | CRISPR/CPF1 SYSTEMS AND METHODS | US15821736 | 2017-11-22 | US20180187176A1 | 2018-07-05 | Mark Aaron Behlke; Michael Allen Collingwood; Rolf Turk; Christopher Anthony Vakulskas |
| This invention pertains to recombinant AsCpf1 and LbCpf1 nucleic acids and polypeptides for use in CRISPR/Cpf1 endonuclease systems and mammalian cell lines encoding recombinant AsCpf1 or LbCpf1 polypeptides. The invention includes recombinant ribonucleoprotein complexes and CRSPR/Cpf1 endonuclease systems having a suitable AsCpf1 crRNA is selected from a length-truncated AsCpf1 crRNA, a chemically-modified AsCpf1 crRNA, or an AsCpf1 crRNA comprising both length truncations and chemical modifications. Methods of performing gene editing using these systems and reagents are also provided. | ||||||
| 5 | METHODS FOR INCREASING CAS9-MEDIATED ENGINEERING EFFICIENCY | US15887893 | 2018-02-02 | US20180171360A1 | 2018-06-21 | Peter Sean Cameron; Rachel E. Haurwitz; Andrew P. May; Christopher H. Nye; Megan van Overbeek |
| Methods for use with Type II CRISPR-Cas9 systems for increasing Cas9-mediated genome engineering efficiency are disclosed. The methods can be used to decrease the number of off-target nucleic acid double-stranded breaks and/or to enhance homology-directed repair of a cleaved target nucleic acid. | ||||||
| 6 | Methods for increasing CAS9-mediated engineering efficiency | US14836753 | 2015-08-26 | US09970030B2 | 2018-05-15 | Peter Sean Cameron; Rachel E. Haurwitz; Andrew P. May; Christopher H. Nye; Megan van Overbeek |
| Methods for use with Type II CRISPR-Cas9 systems for increasing Cas9-mediated genome engineering efficiency are disclosed. The methods can be used to decrease the number of off-target nucleic acid double-stranded breaks and/or to enhance homology-directed repair of a cleaved target nucleic acid. | ||||||
| 7 | METHOD OF TREATING A FABRIC | EP16167256.3 | 2016-04-27 | EP3088503B1 | 2018-05-23 | LANT, Neil Joseph; WOOD, Rebecca Louise; GUMMEL, Jeremie Robert Marcel |
| A method of treating a fabric, comprising contacting the fabric with an aqueous liquor comprising a fabric care component selected from the group consisting of cationic softening-compounds, silicone softening-compounds, paraffins, dispersible polyolefins, waxes and mixtures thereof; and contacting the fabric with an aqueous liquor comprising a nuclease enzyme, preferably a deoxyribonuclease or ribonuclease enzyme. The aqueous liquor may be provided by adding a cleaning or treatment composition to water. Preferably the composition | ||||||
| 8 | METHODS FOR INCREASING CAS9-MEDIATED ENGINEERING EFFICIENCY | EP15763698.6 | 2015-08-26 | EP3186376A1 | 2017-07-05 | CAMERON, Peter, Sean; HAURWITZ, Rachel, E.; MAY, Andrew, P.; NYE, Christopher, H; VAN OVERBEEK, Megan |
| Methods for use with Type II CRISPR-Cas9 systems for increasing Cas9-mediated genome engineering efficiency are disclosed. The methods can be used to decrease the number of off-target nucleic acid double-stranded breaks and/or to enhance homology-directed repair of a cleaved target nucleic acid. | ||||||
QQ群二维码
意见反馈
意见反馈