| 序号 | 专利名 | 申请号 | 申请日 | 公开（公告）号 | 公开（公告）日 | 发明人 |
|---|---|---|---|---|---|---|
| 1 | 重组细胞以及β-水芹烯的生产方法 | CN201380060882.4 | 2013-09-19 | CN104797704A | 2015-07-22 | 古谷昌弘; 上西章太; 岩佐航一郎; 郡悌之; 高桥征司; 下山武文 |
| 本发明要解决的问题在于，提供一种用于高纯度且大量地获得β-水芹烯的一系列的技术。提供一种具有β-水芹烯生产能力的重组细胞，其将选自编码牻牛儿基二磷酸(GPP)合成酶的核酸及编码橙花基二磷酸(NPP)合成酶的核酸构中的至少1种核酸和编码β-水芹烯合成酶的核酸导入宿主细胞而成，且这些核酸在宿主细胞内表达。提供一种β-水芹烯的生产方法，其通过培养该重组细胞来使该重组细胞生产β-水芹烯。 | ||||||
| 2 | Recombinant cell, and method for producing β-phellandrene | US14429510 | 2013-09-19 | US09617563B2 | 2017-04-11 | Masahiro Furutani; Akihiro Uenishi; Koichiro Iwasa; Yasuyuki Kori; Seiji Takahashi; Takefumi Shimoyama |
| To provide a series of techniques for obtaining β-phellandrene with high purity and in a large quantity.Provided is a recombinant cell capable of producing β-phellandrene, prepared by introducing at least one nucleic acid selected from the group consisting of a nucleic acid encoding geranyl pyrophosphate (GPP) synthase and a nucleic acid encoding neryl pyrophosphate (NPP) synthase, and a nucleic acid encoding β-phellandrene synthase into a host cell in such a manner that these nucleic acids are expressed in the host cell. Also provided is a method for producing β-phellandrene by culturing the recombinant cell to produce β-phellandrene in the recombinant cell. | ||||||
| 3 | RECOMBINANT CELL, AND METHOD FOR PRODUCING BETA-PHELLANDRENE | US14429510 | 2013-09-19 | US20150218589A1 | 2015-08-06 | Masahiro Furutani; Akihiro Uenishi; Koichiro Iwasa; Yasuyuki Kori; Seiji Takahashi; Takefumi Shimoyama |
| To provide a series of techniques for obtaining β-phellandrene with high purity and in a large quantity.Provided is a recombinant cell capable of producing β-phellandrene, prepared by introducing at least one nucleic acid selected from the group consisting of a nucleic acid encoding geranyl pyrophosphate (GPP) synthase and a nucleic acid encoding neryl pyrophosphate (NPP) synthase, and a nucleic acid encoding β-phellandrene synthase into a host cell in such a manner that these nucleic acids are expressed in the host cell. Also provided is a method for producing β-phellandrene by culturing the recombinant cell to produce β-phellandrene in the recombinant cell. | ||||||
| 4 | RECOMBINANT CELLS AND PRODUCTION METHOD OF β-PHELLANDRENE | JP2013119612 | 2013-06-06 | JP2014076042A | 2014-05-01 | FURUYA MASAHIRO; IWASA KOICHIRO; KORI TOMOYUKI; UENISHI SHOTA; TAKAHASHI SEIJI; SHIMOYAMA TAKEFUMI |
| PROBLEM TO BE SOLVED: To provide a set of techniques to obtain β-phellandrene in high purity and in a large amount.SOLUTION: There are provided recombinant cells capable of producing β-phellandrene which is produced by introducing at least one nucleic acid selected from the group consisting of a nucleic acid coding for geranyl diphosphate (GPP) synthase and a nucleic acid coding for neryl diphosphate (NPP) synthase, and a nucleic acid coding for β-phellandrene synthase into host cells, and the nucleic acids are expressed in the host cells. There is also provided a production method of β-phellandrene comprising culturing the recombinant cells thereby allowing the recombinant cells to produce β-phellandrene. | ||||||
| 5 | RECOMBINANT CELL, AND METHOD FOR PRODUCING BETA-PHELLANDRENE | EP13838825 | 2013-09-19 | EP2899263A4 | 2016-04-13 | FURUTANI MASAHIRO; UENISHI AKIHIRO; IWASA KOICHIRO; KORI YASUYUKI; TAKAHASHI SEIJI; SHIMOYAMA TAKEFUMI |
| To provide a series of techniques for obtaining ² -phellandrene with high purity and in a large quantity. Provided is a recombinant cell capable of producing ² -phellandrene, prepared by introducing at least one nucleic acid selected from the group consisting of a nucleic acid encoding geranyl pyrophosphate (GPP) synthase and a nucleic acid encoding neryl pyrophosphate (NPP) synthase, and a nucleic acid encoding ² -phellandrene synthase into a host cell in such a manner that these nucleic acids are expressed in the host cell. Also provided is a method for producing ² -phellandrene by culturing the recombinant cell to produce ² -phellandrene in the recombinant cell. | ||||||
| 6 | RECOMBINANT CELL, AND METHOD FOR PRODUCING BETA-PHELLANDRENE | EP13838825.1 | 2013-09-19 | EP2899263A1 | 2015-07-29 | FURUTANI, Masahiro; UENISHI, Akihiro; IWASA, Koichiro; KORI, Yasuyuki; TAKAHASHI, Seiji; SHIMOYAMA, Takefumi |
To provide a series of techniques for obtaining β-phellandrene with high purity and in a large quantity. Provided is a recombinant cell capable of producing β-phellandrene, prepared by introducing at least one nucleic acid selected from the group consisting of a nucleic acid encoding geranyl pyrophosphate (GPP) synthase and a nucleic acid encoding neryl pyrophosphate (NPP) synthase, and a nucleic acid encoding β-phellandrene synthase into a host cell in such a manner that these nucleic acids are expressed in the host cell. Also provided is a method for producing β-phellandrene by culturing the recombinant cell to produce β-phellandrene in the recombinant cell. |
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| 7 | 재조합 세포, 및 β-펠란드렌의 생산 방법 | KR1020157008333 | 2013-09-19 | KR1020150059649A | 2015-06-01 | 후루따니,마사히로; 우에니시,아끼히로; 이와사,고이찌로; 고리,야스유끼; 다까하시,세이지; 시모야마,다께후미 |
| 본발명은, β-펠란드렌을고순도이면서도대량으로취득하기위한일련의기술을제공하는것을과제로한다. 게라닐이인산(GPP) 합성효소를코딩하는핵산및 네릴이인산(NPP) 합성효소를코딩하는핵산으로이루어지는군으로부터선택된적어도 1개의핵산과, β-펠란드렌합성효소를코딩하는핵산이숙주세포에도입되어이루어지고, 또한이들핵산이숙주세포내에서발현되는, β-펠란드렌생산능을갖는재조합세포가제공된다. 당해재조합세포를배양함으로써, 당해재조합세포에β-펠란드렌을생산시키는β-펠란드렌의생산방법도제공된다. | ||||||
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