1 |
制备氨甲酰磷酸和尿素的方法 |
CN201280039707.2 |
2012-06-15 |
CN103930559A |
2014-07-16 |
J·E·亨尼西; A·菲尔布鲁克; D·M·巴特库斯; C·J·伊斯顿; C·斯科特; J·G·奥克肖特; H-K·金; M·J·拉特 |
本发明涉及一种制备氨甲酰磷酸的方法,所述方法包括在氨基甲酸激酶的存在下使组合物中的氨、ATP、碳酸氢盐和CO2或其水合形式反应,其中将所述氨和CO2或其水合形式在化学反应中转化为氨基甲酸,并且将所述氨基甲酸和ATP在通过氨基甲酸激酶进行的酶催化反应中转化为氨甲酰磷酸,并且其中所述组合物的pH为约8-约12。本发明还涉及制备尿素的方法。 |
2 |
Methods of Producing Carbamoyl Phosphate and Urea |
US14125259 |
2012-06-15 |
US20140377815A1 |
2014-12-25 |
James Edward Hennessy; Amy Philbrook; Daniel Miles Bartkus; Christopher John Easton; Colin Scott; John G. Oakeshott; Hye-Kyung Kim; Melissa Jane Latter |
The present invention relates to a method of producing carbamoyl phosphate, the method comprising reacting ammonia, ATP, bicarbonate and CO2, or a hydrated form thereof, in a composition in the presence of a carbamate kinase, wherein the ammonia and CO2, or hydrated form thereof, are converted to carbamate in a chemical reaction and the carbamate and ATP are converted to carbamoyl phosphate in an enzyme-catalysed reaction by the carbamate kinase, and wherein the pH of the composition is about 8 to about 12. The invention also relates to methods of producing urea. |
3 |
Method of generating a carbamoyl phosphate and urea |
JP2014515003 |
2012-06-15 |
JP2014521309A |
2014-08-28 |
ジェームズ・エドワード・ヘネシー; エイミー・フィルブルック; ダニエル・マイルス・バートクス; クリストファー・ジョン・イーストン; コリン・スコット; ジョン・ジー・オークショット; ヒェ−キュン・キム; メリッサ・ジェイン・ラター |
本発明は、カルバミン酸キナーゼの存在下における組成物において、アンモニア、ATP、炭酸水素塩およびCO
2またはその水和物形態を反応させるステップを含み、アンモニアおよびCO
2またはその水和物形態が、化学反応においてカルバメートに変換され、カルバメートおよびATPが、カルバミン酸キナーゼによる酵素触媒反応においてカルバモイルリン酸に変換され、前記組成物のpHが、約8〜約12である、カルバモイルリン酸を生成する方法に関する。 本発明はまた、尿素を生成する方法に関する。 |
4 |
METHODS OF PRODUCING CARBAMOYL PHOSPHATE AND UREA |
EP12800536.0 |
2012-06-15 |
EP2721168A1 |
2014-04-23 |
HENNESSY, James Edward; PHILBROOK, Amy; BARTKUS, Daniel Miles; EASTON, Christopher John; SCOTT, Colin; OAKESHOTT, John G.; KIM, Hye-Kyung; LATTER, Melissa Jane |
The present invention relates to a method of producing carbamoyl phosphate, the method comprising reacting ammonia, ATP, bicarbonate and CO
2, or a hydrated form thereof, in a composition in the presence of a carbamate kinase, wherein the ammonia and C02, or hydrated form thereof, are converted to carbamate in a chemical reaction and the carbamate and ATP are converted to carbamoyl phosphate in an enzyme-catalysed reaction by the carbamate kinase, and wherein the pH of the composition is about 8 to about 12. The invention also relates to methods of producing urea |
5 |
METHODS OF PRODUCING CARBAMOYL PHOSPHATE AND UREA |
EP12800536 |
2012-06-15 |
EP2721168A4 |
2015-06-10 |
HENNESSY JAMES EDWARD; PHILBROOK AMY; BARTKUS DANIEL MILES; EASTON CHRISTOPHER JOHN; SCOTT COLIN; OAKESHOTT JOHN G; KIM HYE-KYUNG; LATTER MELISSA JANE |
|
6 |
카바모일 포스페이트 및 우레아 제조 방법 |
KR1020147001420 |
2012-06-15 |
KR1020140063569A |
2014-05-27 |
헤네시제임스에드워드; 필브룩에이미; 바르트커스다니엘마일즈; 이스턴크리스토퍼존; 스코트콜린; 오케쇼트존지.; 김혜경; 래터멜리사제인 |
본 발명은 상기 방법은 카바메이트 키나아제의 존재 하에 조성물 내에서 암모니아, ATP, 중탄산염 및 CO
2 , 또는 이들의 수화형을 반응시키는 단계를 포함하는 카바모일 포스페이트 생산 방법에 관한 것으로서, 여기서 상기 암모니아 및 CO
2 , 또는 이들의 수화형은 화학 반응 내에서 카바메이트로 전환되고 상기 카바메이트 및 ATP는 카바메이트 키나아제에 의하여 효소-촉매되는 반응에서 카바모일 포스페이트로 전환되며, 여기서 상기 조성물의 pH는 약 8 내지 약 12이다. 또한, 본 발명은 우레아 생산 방법에 관한 것이다. |