序号 专利名 申请号 申请日 公开(公告)号 公开(公告)日 发明人
1 Secretagogues derived from oxalobacter formigenes US14902484 2014-07-03 US10125176B2 2018-11-13 Elisabeth Lindner; Helena Cowley; Aaron Cowley; Maria Akerman
The present invention relates to a secretagogue compound derived from oxalate degrading bacteria, for use in the treatment of an oxalate related disease and/or oxalate related imbalance in a subject, wherein the administration of the secretagogue results in a reduction of urinary oxalate and/or plasma oxalate in the subject. The invention further relates to a pharmaceutical composition comprising such a secretagogue compound, a method for treating a subject suffering from an oxalate related disease, and to a method for preparing a secretagogue.
2 SECRETAGOGUES DERIVED FROM OXALOBACTER FORMIGENES US14902484 2014-07-03 US20160137701A1 2016-05-19 Elisabeth LINDNER; Helena COWLEY; Aaron COWLEY
The present invention relates to a secretagogue compound derived from oxalate degrading bacteria, for use in the treatment of an oxalate related disease and/or oxalate related imbalance in a subject, wherein the administration of the secretagogue results in a reduction of urinary oxalate and/or plasma oxalate in the subject. The invention further relates to a pharmaceutical composition comprising such a secretagogue compound, a method for treating a subject suffering from an oxalate related disease, and to a method for preparing a secretagogue.
3 NOVEL ACTIVITY OF AHPF PROTEIN OF PSEUDOMONAS AERUGINOSA, AND USE THEREFOR US16036314 2018-07-16 US20180346918A1 2018-12-06 Byung Yeoup Chung; Sudhir Singh; Seung Sik Lee; Hyoung Woo Bai; Sung Beom Lee
An AhpF protein has thioredoxin reductase, peroxidase, and chaperone activities and is derived from Pseudomonas aeruginosa, and a use therefor. By using a novel activity of the AhpF of Pseudomonas aeruginosa according to the present invention, it is possible to produce a plant having strong resistance to various environmental stresses such as oxidative stress or heat stress, thereby making it possible to contribute to increasing crop productivity and mass production of useful constituents. In addition, it is possible to prevent desertification and environmental pollution through the development of transformed plants having resistance to high temperatures and drying.
4 NOVEL ACTIVITY OF AHPF PROTEIN OF PSEUDOMONAS AERUGINOSA, AND USE THEREFOR US15022296 2013-11-20 US20160281104A1 2016-09-29 Byung Yeoup CHUNG; Sudhir SINGH; Seung Sik LEE; Hyoung Woo BAI; Sung Beom LEE
The present invention relates to an AhpF protein which has thioredoxin reductase, peroxidase, and chaperone activities and is derived from Pseudomonas aeruginosa, and a use therefor. By using a novel activity of the AhpF of Pseudomonas aeruginosa according to the present invention, it is possible to produce a plant having strong resistance to various environmental stresses such as oxidative stress or heat stress, thereby making it possible to contribute to increasing crop productivity and mass production of useful constituents. In addition, it is possible to prevent desertification and environmental pollution through the development of transformed plants having resistance to high temperatures and drying.
5 슈도모나스 애루지노사의 AhpF 단백질의 신규 활성 및 이의 용도 KR1020130111916 2013-09-17 KR1020150032428A 2015-03-26 정병엽; 수디르싱; 이승식; 배형우; 이성범
본 발명은 티오레독신 환원효소, 페록시다아제, 및 샤페론의 활성을 갖는, 슈도모나스 애루지노사(Pseudomonas aeruginosa)로부터 유래된 AhpF 단백질, 및 이의 용도에 관한 것으로, 본 발명의 슈도모나스 애루지노사의 AhpF의 새로운 활성을 이용하여, 산화적 스트레스 또는 열 스트레스 등의 다양한 환경스트레스에 대해 강한 내성을 가진 식물체를 제조할 수 있어, 농작물의 생산성 증대 및 유용성분의 대량 생산에 기여할 수 있으며, 고온과 건조 저항성 형질전환 식물체 개발로 사막화와 환경오염을 방지할 수 있다.
6 슈도모나스 애루지노사의 AhpF 단백질의 신규 활성 및 이의 용도 KR1020130111916 2013-09-17 KR101577061B1 2015-12-14 정병엽; 수디르싱; 이승식; 배형우; 이성범
본발명은티오레독신환원효소, 페록시다아제, 및샤페론의활성을갖는, 슈도모나스애루지노사(Pseudomonas aeruginosa)로부터유래된 AhpF 단백질, 및이의용도에관한것으로, 본발명의슈도모나스애루지노사의 AhpF의새로운활성을이용하여, 산화적스트레스또는열 스트레스등의다양한환경스트레스에대해강한내성을가진식물체를제조할수 있어, 농작물의생산성증대및 유용성분의대량생산에기여할수 있으며, 고온과건조저항성형질전환식물체개발로사막화와환경오염을방지할수 있다.
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