Secretagogues derived from oxalobacter formigenes

申请号 US14902484 申请日 2014-07-03 公开(公告)号 US10125176B2 公开(公告)日 2018-11-13
申请人 OXTHERA INTELLECTUAL PROPERTY AB; 发明人 Elisabeth Lindner; Helena Cowley; Aaron Cowley; Maria Akerman;
摘要 The present invention relates to a secretagogue compound derived from oxalate degrading bacteria, for use in the treatment of an oxalate related disease and/or oxalate related imbalance in a subject, wherein the administration of the secretagogue results in a reduction of urinary oxalate and/or plasma oxalate in the subject. The invention further relates to a pharmaceutical composition comprising such a secretagogue compound, a method for treating a subject suffering from an oxalate related disease, and to a method for preparing a secretagogue.
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