序号 | 专利名 | 申请号 | 申请日 | 公开(公告)号 | 公开(公告)日 | 发明人 |
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41 | GLUCOSE DEHYDROGENASE | EP12863747 | 2012-12-28 | EP2799545A4 | 2016-01-20 | SODE KOJI; MORI KAZUSHIGE |
Amino acid mutation(s) can be introduced to Sclerotinia sclerotiorum- or Aspergillus niger-derived glucose dehydrogenase to obtain a glucose dehydrogenase variant with significantly enhanced productivity in E. coli. The glucose dehydrogenase of the present invention is low reactive with xylose. | ||||||
42 | BIOCATALYSTS FOR EZETIMIBE SYNTHESIS | EP11778262.3 | 2011-05-04 | EP2566497B1 | 2015-07-29 | CROWE, Michael, A.; ALVIZO, Oscar; BEHROUZIAN, Behnaz; BONG, Yong Koy; COLLIER, Steven, J.; GOHEL, Anupam; MAVINAHALLI, Jagadeesh; MODUKURU, Naga; MUNDORFF, Emily; SMITH, Derek; SONG, Shiwei; YEO, Wan Lin |
The present disclosure relates to non-naturally occurring polypeptides useful for preparing Ezetimibe, polynucleotides encoding the polypeptides, and methods of using the polypeptides. | ||||||
43 | GLUCOSE DEHYDROGENASE | EP12863747.7 | 2012-12-28 | EP2799545A1 | 2014-11-05 | SODE, Koji; MORI, Kazushige |
Amino acid mutation(s) can be introduced to Sclerotinia sclerotiorum- or Aspergillus niger-derived glucose dehydrogenase to obtain a glucose dehydrogenase variant with significantly enhanced productivity in E. coli. The glucose dehydrogenase of the present invention is low reactive with xylose. |
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44 | BIOCATALYSTS FOR EZETIMIBE SYNTHESIS | EP11778262.3 | 2011-05-04 | EP2566497A1 | 2013-03-13 | CROWE, Michael, A.; ALVIZO, Oscar; BEHROUZIAN, Behnaz; BONG, Yong Koy; COLLIER, Steven, J.; GOHEL, Anupam; MAVINAHALLI, Jagadeesh; MODUKURU, Naga; MUNDORFF, Emily; SMITH, Derek; SONG, Shiwei; YEO, Wan Lin |
The present disclosure relates to non-naturally occurring polypeptides useful for preparing Ezetimibe, polynucleotides encoding the polypeptides, and methods of using the polypeptides. | ||||||
45 | MYCOTOXIN-REDUCING COMPOSITION | EP07824430.8 | 2007-11-01 | EP2094107B1 | 2010-12-29 | Mann, Stephen Philip; Parfitt, David |
A composition comprising an enzyme, a mycotoxin-binding agent and a microorganism capable of taking up a mycotoxin. | ||||||
46 | MYCOTOXIN-REDUCING COMPOSITION | EP07824430.8 | 2007-11-01 | EP2094107A2 | 2009-09-02 | Mann, Stephen Philip; Parfitt, David |
A composition comprising an enzyme, a mycotoxin-binding agent and a microorganism capable of taking up a mycotoxin. | ||||||
47 | CONVERSION OF METHYLGLYOXAL INTO HYDROXYACETONE USING ENZYMES AND APPLICATIONS THEREOF | EP16306848.9 | 2016-12-29 | EP3342873A1 | 2018-07-04 | FAURE, Laetitia; BESTEL-CORRE, Gwenaëlle; RAYNAUD, Céline; DUMON-SEIGNOVERT, Laurence |
The present invention relates to new methylglyoxal reductase (MGR) enzymes which are useful for efficiently converting methylglyoxal into hydroxyacetone. The invention more particularly relates to a method for efficiently converting methylglyoxal into hydroxyacetone using said enzymes, to a method for producing 1,2-propanediol using a microorganism overexpressing said enzymes, and to said microorganism. |
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48 | BIOCATALYTIC PROCESS FOR PREPARING ESLICARBAZEPINE AND ANALOGS THEREOF | EP12771861.7 | 2012-04-12 | EP2697662B1 | 2018-06-06 | GOHEL, Anupam; SMITH, Derek; WONG, Brian; SUKUMARAN, Joly; YEO, Wan Lin; COLLIER, Steven, J.; NOVICK, Scott |
The present disclosure relates to biocatalysts and its uses for the efficient preparation of eslicarbazepine, eslicarbazepine acetate, and analogs thereof. | ||||||
49 | MANUFACTURING METHOD FOR IMPROVED PROTEIN-CONTAINING FOOD AND FORMULATION FOR IMPROVING PROTEIN-CONTAINING FOOD | EP15734961.4 | 2015-01-07 | EP3092907A1 | 2016-11-16 | SATO, Hiroaki; NAKAGOSHI, Hiroyuki; KOTANI, Masao; KOBAYASHI, Yoshie |
A method for producing a modified food containing a protein and a preparation for modifying a food containing a protein are provided. A food raw material containing a protein is treated by using an oxidizing agent and/or an oxidoreductase in combination with a metal and/or a metal-containing substance to produce a food containing a protein. |
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50 | METHODS OF PRODUCING OMEGA-HYDROXYLATED FATTY ACID DERIVATIVES | EP14738962.1 | 2014-06-16 | EP2984490A1 | 2016-02-17 | SCHIRMER, Andreas, W.; WANG, Haibo; DEL CARDAYRE, Stephen, B.; HU, Zhihao; HOM, Louis, G.; ZHU, Baolong; CHANG, Cindy; POPOVA, Emanuela, E. |
The disclosure relates to omega-hydroxylated fatty acid derivatives and methods of producing them. Herein, the disclosure encompasses a novel and environmentally friendly production method that provides omega-hydroxylated fatty acid derivatives at high purity and yield. Further encompassed are recombinant microorganisms that produce omega-hydroxylated fatty acid derivatives through selective fermentation. | ||||||
51 | BIOCATALYTIC PROCESS FOR PREPARING ESLICARBAZEPINE AND ANALOGS THEREOF | EP12771861 | 2012-04-12 | EP2697662A4 | 2015-07-01 | GOHEL ANUPAM; SMITH DEREK; WONG BRIAN; SUKUMARAN JOLY; YEO WAN LIN; COLLIER STEVEN J; NOVICK SCOTT |
The present disclosure relates to biocatalysts and its uses for the efficient preparation of eslicarbazepine, eslicarbazepine acetate, and analogs thereof. | ||||||
52 | BIOCATALYTIC PROCESS FOR PREPARING ESLICARBAZEPINE AND ANALOGS THEREOF | EP12771861.7 | 2012-04-12 | EP2697662A2 | 2014-02-19 | GOHEL, Anupam; SMITH, Derek; WONG, Brian; SUKUMARAN, Joly; YEO, Wan Lin; COLLIER, Steven, J.; NOVICK, Scott |
The present disclosure relates to biocatalysts and its uses for the efficient preparation of eslicarbazepine, eslicarbazepine acetate, and analogs thereof. | ||||||
53 | 포도당 탈수소 효소 | KR1020147020334 | 2012-12-28 | KR101766522B1 | 2017-08-08 | 소데,코지; 모리,카즈시게 |
및유래의포도당탈수소효소에서특정아미노산변이를도입하여대장균의생산성이현저하게높아진변이포도당탈수소효소를얻을수 있다. 본발명의포도당탈수소효소는크실로오스대해반응성이낮다. | ||||||
54 | 오메가-수산화 지방산 유도체를 생성하는 방법들 | KR1020167000963 | 2014-06-16 | KR1020160020516A | 2016-02-23 | 셔머,안드레아스,더블유.; 왕,하이보; 델카다이레,스티븐,비.; 흐,지하오; 홈,루이스,지.; 주,바오롱; 창,신디; 포포바,엠마누엘라,이. |
본발명은오메가-수산화지방산유도체들및 이들을생성하는방법들에관한것이다. 본명세서에서, 본발명은높은순도및 수율로오메가-수산화지방산유도체들을제공하는신규하고환경친화적인생성방법을포함한다. 또한, 선택발효를통해오메가-수산화지방산유도체들을생성하는재조합미생물들이포함된다. | ||||||
55 | PROCESSES USING AMINO ACID DEHYDROGENASES AND KETOREDUCTASE-BASED COFACTOR REGENERATING SYSTEM | PCT/US2011024102 | 2011-02-08 | WO2011100265A3 | 2011-12-29 | CABIROL FABIEN L; COLLIER STEVEN J; DAUSSMANN THOMAS; MODUKURU NAGA |
The present disclosure relates to the use of an amino acid dehydrogenase in combination with a cofactor regenerating system comprising a ketoreductase. In particular embodiments, the process can be used to prepare L-tert-leucine using a leucine dehydrogenase. | ||||||
56 | MYCOTOXIN-REDUCING COMPOSITION | PCT/GB2007004191 | 2007-11-01 | WO2008053232A3 | 2008-08-21 | MANN STEPHEN PHILIP; PARFITT DAVID |
A composition comprising an enzyme, a mycotoxin-binding agent and a microorganism capable of taking up a mycotoxin. | ||||||
57 | MANUFACTURING METHOD FOR IMPROVED PROTEIN-CONTAINING FOOD AND FORMULATION FOR IMPROVING PROTEIN-CONTAINING FOOD | PCT/JP2015050211 | 2015-01-07 | WO2015105112A9 | 2016-06-02 | SATO HIROAKI; NAKAGOSHI HIROYUKI; KOTANI MASAO; KOBAYASHI YOSHIE |
Provided is a manufacturing method for an improved protein-containing food and a formulation for improving protein-containing food. A protein-containing food is manufactured by processing a food raw material containing protein with an oxidizer and/or an oxidoreductase, and a metal and/or a metal-containing material. | ||||||
58 | COMPOSITIONS, METHODS, AND DEVICES FOR DIALYSIS | PCT/US2014041318 | 2014-06-06 | WO2014197806A3 | 2015-01-08 | MARGOLIN ALEXEY; GRUJIC DANICA; PIERZYNOWSKI STEFAN |
Compositions of peritoneal dialysis solutions and metabolizing enzymes, and their uses to treat disorders associated with elevated levels of metabolites are disclosed. Animal models of hyperoxalemia are also disclosed. | ||||||
59 | BIOCATALYTIC PROCESS FOR PREPARING ESLICARBAZEPINE AND ANALOGS THEREOF | PCT/US2012033347 | 2012-04-12 | WO2012142302A3 | 2014-05-01 | GOHEL ANUPAM; SMITH DEREK; WONG BRIAN; SUKUMARAN JOLY; YEO WAN LIN; COLLIER STEVEN J; NOVICK SCOTT |
The present disclosure relates to biocatalysts and its uses for the efficient preparation of eslicarbazepine, eslicarbazepine acetate, and analogs thereof. |