PROCESSES USING AMINO ACID DEHYDROGENASES AND KETOREDUCTASE-BASED COFACTOR REGENERATING SYSTEM

申请号 PCT/US2011024102 申请日 2011-02-08 公开(公告)号 WO2011100265A3 公开(公告)日 2011-12-29
申请人 CODEXIS INC; CABIROL FABIEN L; COLLIER STEVEN J; DAUSSMANN THOMAS; MODUKURU NAGA; 发明人 CABIROL FABIEN L; COLLIER STEVEN J; DAUSSMANN THOMAS; MODUKURU NAGA;
摘要 The present disclosure relates to the use of an amino acid dehydrogenase in combination with a cofactor regenerating system comprising a ketoreductase. In particular embodiments, the process can be used to prepare L-tert-leucine using a leucine dehydrogenase.
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