序号 专利名 申请号 申请日 公开(公告)号 公开(公告)日 发明人
21 Antibiotic compound JP2757282 1982-02-24 JPS57171925A 1982-10-22 KONISHI MASATAKA; MIYAGI TAKEO; TSUKIURA HIROSHI; KAWAGUCHI HIROSHI
NEW MATERIAL:A peptide of formulaI(R is H, group of formula II, III or IV; Dab is alpha, gamma-diaminobutyric acid; Leu is leucine; Phe is phenylalanine). EXAMPLE:Bu-2470A ( C41H71N13O8.5HCl.4H2O). USE:Antibiotic. PREPARATION:Bacillus circulans strain G493-B6 (ATCC 31,805) is cultured in an aqueous enriched medium containing assimilable carbon and nitrogen sources under submerged aeration conditions until a practical amount of Bu-2470 complex is accumulated and the Bu-2470 complex is collected from the culture medium without cotamination with other substances simultaneously formed. The cultivation temperature is 20-45 deg.C and fermentation is conducted at 25-35, preferably 27-32 deg.C.
22 Koseibutsushitsuno seizoho JP7851574 1974-07-09 JPS519789A 1976-01-26 MACHIDA SADAO; SAWADA JIRO; OOMURA SADAFUMI; YASUI HAJIME
A strain TM-743 of Bacillus circulans (ATCC no. 31 154) is used for the manufacture of an antibiotic called TM-743. This antibiotic has a high antibacterial activity against pathogenic microorganisms, in particular against Gram-negative bacteria. The TM-743 antibiotic is obtained, for example in the form of its hydrochloride, which is in the form of a white powder, by culturing the strain of Bacillus circulans in a culture medium, by extracting the TM-743, in the form of a solution, from the culture medium and then by separating the TM-743 from the extract solution.
23 바실루스속 세균 아포의 제조 방법 KR1020177031419 2016-04-08 KR1020170135888A 2017-12-08 에구치다카노리; 모리시타야스유키; 츠카고시유키
바실루스속세균을, C/N 비 (탄소함량과질소함량의중량비) 가 4 보다크고 9.5 미만인액체배지를사용하여배양하는공정을포함하는, 바실루스속세균의아포의제조방법.
24 분기 α-글루칸, 이를 생성하는 α-글루코실 전이 효소, 및 그의 제조 방법 및 용도 KR1020097023044 2008-04-23 KR1020100016213A 2010-02-12 와타나베히카루; 야마모토다쿠오; 니시모토도모유키; 쓰사키게이지; 오쿠가즈유키; 차엔히로토; 후쿠다시게하루
It is intended to provide a glucan useful as a water-soluble dietary fiber, a method for producing the same, and use thereof. The object is achieved by providing a branched α-glucan, which is an α-glucan including glucose as a constituent sugar and is characterized by having the following features based on a methylation analysis: (1) a ratio of 2,3,6-trimethyl-1,4,5-triacetylglucitol to 2,3,4-trimethyl-1,5,6-triacetylglucitol is in the range from 1:0.6 to 1:4; (2) the total amount of 2,3,6-trimethyl-1,4,5-triacetylglucitol and 2,3,4-trimethyl-1,5,6-triacetylglucitol is 60% or more of partially methylated glucitol acetate; (3) the amount of 2,4,6-trimethyl-1,3,5-triacetylglucitol is 0.5% or more and less than 10% of partially methylated glucitol acetate; and (4) the amount of 2,4-dimethyl-1,3,5,6-tetraacetylglucitol is 0.5% or more of partially methylated glucitol acetate, a novel α-glucosyltransferase producing the branched α-glucan, a method for producing the same and use thereof.
25 분기 α-글루칸, 이를 생성하는 α-글루코실 전이 효소, 및 그의 제조 방법 및 용도 KR1020097023044 2008-04-23 KR101540230B1 2015-07-29 와타나베히카루; 야마모토다쿠오; 니시모토도모유키; 쓰사키게이지; 오쿠가즈유키; 차엔히로토; 후쿠다시게하루
수용성식물섬유로서유용한글루칸과그의제조방법및 용도를제공하는것을과제로하고, 글루코오스를구성당으로하는α-글루칸으로서, 메틸화분석에서, (1) 2, 3, 6-트리메틸-1, 4, 5-트리아세틸글루시톨과 2, 3, 4-트리메틸-1, 5, 6-트리아세틸글루시톨의비가 1: 0.6 내지 1:4의범위에있고, (2) 2, 3, 6-트리메틸-1, 4, 5-트리아세틸글루시톨과 2, 3, 4-트리메틸-1, 5, 6-트리아세틸글루시톨의합계가부분메틸화글루시톨아세테이트의 60% 이상을차지하며, (3) 2, 4, 6-트리메틸-1, 3, 5-트리아세틸글루시톨이부분메틸화글루시톨아세테이트의 0.5% 이상 10% 미만이고, (4) 2, 4-디메틸-1, 3, 5, 6-테트라아세틸글루시톨이부분메틸화글루시톨아세테이트의 0.5% 이상인특징을갖는분기α-글루칸; 상기분기α-글루칸을생성하는신규한α-글루코실전이효소; 그의제조방법및 용도를제공함으로써상기과제를해결한다.
26 바실러스속 미생물이 흡착되어 탈취 효과가 우수한건강기능성 의류 및 그의 제조방법 KR1020080035226 2008-04-16 KR1020090109810A 2009-10-21 이희원
PURPOSE: Bacillus species-absorbed functional clothing with high deodorization effect and a preparation method thereof are provided to sterilize and decompose sweat, fat, and protein secreted from the body by absorbed bacillus species. CONSTITUTION: A preparation method for Bacillus species-absorbed functional clothing with high deodorization effect comprises the steps of: inoculating Bacillus species microorganism in a sterilized culture medium in the amount of 0.01-0.1 weight%; obtaining a culture fluid by culturing the microorganism for 20 - 30 hours while performing aeration with an oxygen supply amount of 15-30 ?“/min at 35-40°C; dipping the clothes for absorbing at 30-35°C for 1-2 hours; absorbing Bacillus species microorganism on the surface and inside of the clothes; and dehydrating and drying the Bacillus species-absorbed clothing.
27 バチルス属細菌芽胞の製造方法 JP2017511100 2016-04-08 JPWO2016163534A1 2018-02-01 江口 貴紀; 森下 康行; 塚越 裕樹
バチルス属細菌を、C/N比(炭素含量と窒素含量の重量比)が4より大きく9.5未満である液体培地を用いて培養する工程を含む、バチルス属細菌の芽胞の製造方法。
28 分岐α−グルカン及びこれを生成するα−グルコシル転移酵素とそれらの製造方法並びに用途 JP2017091488 2017-05-01 JP2017137506A 2017-08-10 渡邊 光; 山本 拓生; 西本 友之; 津▲崎▼ 桂二; 奥 和之; 茶圓 博人; 福田 恵温
【課題】 溶性食物繊維として有用なグルカンとその製造方法並びにその用途を提供することを課題とする。
【解決手段】 グルコースを構成糖とするα−グルカンであって、メチル化分析において、(1)2,3,6−トリメチル−1,4,5−トリアセチルグルシトールと2,3,4−トリメチル−1,5,6−トリアセチルグルシトールの比が1:0.6乃至1:4の範囲にある;(2)2,3,6−トリメチル−1,4,5−トリアセチルグルシトールと2,3,4−トリメチル−1,5,6−トリアセチルグルシトールとの合計が部分メチル化グルシトールアセテートの60%以上を占める;(3)2,4,6−トリメチル−1,3,5−トリアセチルグルシトールが部分メチル化グルシトールアセテートの0.5%以上10%未満である;及び(4)2,4−ジメチル−1,3,5,6−テトラアセチルグルシトールが部分メチル化グルシトールアセテートの0.5%以上である;ことを特徴とする分岐α−グルカンと当該分岐α−グルカンを生成する新規なα−グルコシル転移酵素、それらの製造方法並びに用途を提供することによって、上記課題を解決する。
【選択図】 なし
29 分岐α−グルカン及びこれを生成するα−グルコシル転移酵素とそれらの製造方法並びに用途 JP2016042102 2016-03-04 JP2016116532A 2016-06-30 渡邊 光; 山本 拓生; 西本 友之; 津▲崎▼ 桂二; 奥 和之; 茶圓 博人; 福田 恵温
【課題】 溶性食物繊維として有用なグルカンとその製造方法並びにその用途を提供することを課題とする。
【解決手段】 グルコースを構成糖とするα−グルカンであって、メチル化分析において、(1)2,3,6−トリメチル−1,4,5−トリアセチルグルシトールと2,3,4−トリメチル−1,5,6−トリアセチルグルシトールの比が1:0.6乃至1:4の範囲にある;(2)2,3,6−トリメチル−1,4,5−トリアセチルグルシトールと2,3,4−トリメチル−1,5,6−トリアセチルグルシトールとの合計が部分メチル化グルシトールアセテートの60%以上を占める;(3)2,4,6−トリメチル−1,3,5−トリアセチルグルシトールが部分メチル化グルシトールアセテートの0.5%以上10%未満である;及び(4)2,4−ジメチル−1,3,5,6−テトラアセチルグルシトールが部分メチル化グルシトールアセテートの0.5%以上である;ことを特徴とする分岐α−グルカンと当該分岐α−グルカンを生成する新規なα−グルコシル転移酵素、それらの製造方法並びに用途を提供することによって、上記課題を解決する。
【選択図】 なし
30 分岐α−グルカン及びこれを生成するα−グルコシル転移酵素とそれらの製造方法並びに用途 JP2014152414 2014-07-25 JP5918813B2 2016-05-18 渡邊 光; 山本 拓生; 西本 友之; 津▲崎▼ 桂二; 奥 和之; 茶圓 博人; 福田 恵温
31 分岐α−グルカン及びこれを生成するα−グルコシル転移酵素とそれらの製造方法並びに用途 JP2014152415 2014-07-25 JP5858547B2 2016-02-10 渡邊 光; 山本 拓生; 西本 友之; 津▲崎▼ 桂二; 奥 和之; 茶圓 博人; 福田 恵温
32 BRANCHED α-GLUCAN AND α-GLUCOSYLTRANSFERASE GENERATING THE SAME, AND THEIR PREPARATION METHOD AND USE JP2013151138 2013-07-19 JP2013252137A 2013-12-19 WATANABE HIKARU; YAMAMOTO TAKUO; NISHIMOTO TOMOYUKI; TSUZAKI KEIJI; OKU KAZUYUKI; CHAEN HIROTO; FUKUDA SHIGEHARU
PROBLEM TO BE SOLVED: To provide a preparation method of a mixture of a novel branched α-glucan.SOLUTION: A preparation method of a mixture of a branched α-glucan including a branched α-glucan, includes a process in which an α-glucosyltransferase and a cyclomaltodextrin glucanotransferase are made to act to a starch raw material. The branched α-glucan has a branched structure in which connection is performed to a non-reducing end glucose residue located at one end of a straight chain glucan connected through an α-1,4 bond, through an α 1,3 bond or an α-1,6 bond, and has a glucose polymerization degree by a molecular weight distribution analysis based on a gel filtration high speed liquid chromatogram that is in a range of 6 to 62.
33 Branch α- glucan and to generate this α- glucosyltransferase and their preparation and uses JP2010262148 2010-11-25 JP4755310B2 2011-08-24 和之 奧; 拓生 山本; 桂二 津▲崎▼; 光 渡邊; 恵温 福田; 博人 茶圓; 友之 西本
34 Branch α- glucan and to generate this α- glucosyltransferase and their preparation and uses JP2010132735 2010-06-10 JP4755295B2 2011-08-24 和之 奧; 拓生 山本; 桂二 津▲崎▼; 光 渡邊; 恵温 福田; 博人 茶圓; 友之 西本
35 BRANCHED α-GLUCAN, α-GLUCOSYL TRANSFERASE FOR PRODUCING THE SAME, MANUFACTURING METHOD AND USE THEREFOR JP2010132735 2010-06-10 JP2010202884A 2010-09-16 WATANABE HIKARU; YAMAMOTO TAKUO; NISHIMOTO TOMOYUKI; TSUZAKI KEIJI; OKU KAZUYUKI; CHAEN HIROTO; FUKUDA SHIGEHARU
<P>PROBLEM TO BE SOLVED: To provide glucan useful as a water-soluble dietary fiber, manufacturing methods and use therefor. <P>SOLUTION: The branched α-glucan is an α-glucan making glucose as a constitution sugar and has a branched structure with a glucose polymerization degree of 1 or more connected to at least non-reduction terminal end in a linear glucan with a glucose polymerization degree of 3 or more connected through an α-1,4 bond through a bond other than the α-1,4 bond, specifically is the branched α-glucan having the following characteristic in methylation analysis. The branched α-glucan characterized in that (1) a ratio of 2,3,6-trimethyl-1,4,5-triacetylglucitol and 2,3,4-trimethyl-1,5,6-triacetylglucitol is in a range of 1:0.6 to 1:4, (2) a total of 2,3,6-trimethyl-1,4,5-triacetylglucitol and 2,3,4-trimethyl-1,5,6-triacetylglucitol occupies 60% or more of a partially methylated glucitolacetate, (3) 2,4,6-trimethyl-1,3,5-triacetylglucitol is ≥0.5% and <10% of the partially methylated glucitolacetate, and (4) 2,4-dimethyl-1,3,5,6-tetraacetylglucitol is 0.5% or more of the partially methylated glucitolacetate, the novel α-glucosyl transferase for producing the branched α-glucan, the manufacturing methods and use therefor are provided. <P>COPYRIGHT: (C)2010,JPO&INPIT
36 BRANCHED α-GLUCAN, α-GLUCOSYL TRANSFERASE FOR PRODUCING THE SAME, MANUFACTURING METHOD AND USE THEREFOR JP2010132717 2010-06-10 JP2010202883A 2010-09-16 WATANABE HIKARU; YAMAMOTO TAKUO; NISHIMOTO TOMOYUKI; TSUZAKI KEIJI; OKU KAZUYUKI; CHAEN HIROTO; FUKUDA SHIGEHARU
PROBLEM TO BE SOLVED: To provide glucan useful as a water-soluble dietary fiber, manufacturing methods and use therefor. SOLUTION: The branched α-glucan is an α-glucan making glucose as a constitution sugar and has a branched structure with a glucose polymerization degree of 1 or more connected to at least non-reduction terminal end in a linear glucan with a glucose polymerization degree of 3 or more connected through an α-1,4 bond through a bond other than the α-1,4 bond, specifically is the branched α-glucan having the following characteristic in methylation analysis. The branched α-glucan characterized in that (1) a ratio of 2,3,6-trimethyl-1,4,5-triacetylglucitol and 2,3,4-trimethyl-1,5,6-triacetylglucitol is in a range of 1:0.6 to 1:4, (2) a total of 2,3,6-trimethyl-1,4,5-triacetylglucitol and 2,3,4-trimethyl-1,5,6-triacetylglucitol occupies 60% or more of a partially methylated glucitolacetate, (3) 2,4,6-trimethyl-1,3,5-triacetylglucitol is ≥0.5% and <10% of the partially methylated glucitolacetate, and (4) 2,4-dimethyl-1,3,5,6-tetraacetylglucitol is 0.5% or more of the partially methylated glucitolacetate, the novel α-glucosyl transferase for producing the branched α-glucan, the manufacturing methods and use therefor are provided. COPYRIGHT: (C)2010,JPO&INPIT
37 New heparitinases, its production method and its producing bacteria JP6370791 1991-03-06 JP3110064B2 2000-11-20 浩 丸山; 圭一 吉田; 博文 宮園; 清志 森川
38 JPS5828869B2 - JP4099978 1978-04-07 JPS5828869B2 1983-06-18 TAKAHARA YOSHUKI; HIROSE YOSHITERU; TAKEUCHI YOKO; MURAI ASAO; KAISHO MASATSUNE; MURAO SAWAO
A purified ring peptide antibiotic of the following empirical formula: N alpha -(3-hydroxy-4-methyl-1-oxohexyl)-L- alpha , gamma -diaminobutyryl-L-isoleucyl-L- alpha , gamma -diaminobutyryl-D-phenylalanyl-L-leucyl-L- alpha , gamma -diaminobutyryl-D-valyl-L-leucyl-L-serine (9-1)-lactone and which has the following structural formula: and wherein Dab represents 2,4-diamino butyric acid.
39 Antibiotic perumycin a JP4099978 1978-04-07 JPS54132548A 1979-10-15 TAKAHARA YOSHIYUKI; HIROSE YOSHITERU; TAKEUCHI YOUKO; MURAI ASAO; KAISOU MASATSUNE; MURAO SAWAO
NEW MATERIAL:Perumycin A of the formula (Dab is 2,4-diaminobutyric acid). USE: Antibiotic having strong activity against a wide range of microorgamisms, as gram-positive and negative bacteria and fungi. PREPARATION: Bacillus circulanse AJ 3902 (FERM-P 3097) is incubated in enricned medium usually under shaking or stirring by aeration and combined with extraction with organic solvents, thus isolating perumycin A from the medium. The incubation is performed at 25W45°C for 24W72 hr. COPYRIGHT: (C)1979,JPO&Japio
40 JPS5230597B2 - JP7851574 1974-07-09 JPS5230597B2 1977-08-09
A strain TM-743 of Bacillus circulans (ATCC no. 31 154) is used for the manufacture of an antibiotic called TM-743. This antibiotic has a high antibacterial activity against pathogenic microorganisms, in particular against Gram-negative bacteria. The TM-743 antibiotic is obtained, for example in the form of its hydrochloride, which is in the form of a white powder, by culturing the strain of Bacillus circulans in a culture medium, by extracting the TM-743, in the form of a solution, from the culture medium and then by separating the TM-743 from the extract solution.
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