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序号	专利名	申请号	申请日	公开（公告）号	公开（公告）日	发明人
101	Apparatus and Method for Growing Cells	US13874864	2013-05-01	US20130295662A1	2013-11-07	John J. S. Cadwell; Kevin Barnes
A system and method for culturing cells is provided that includes an extra-capillary space between at least one permeable hollow fiber and an enclosed chamber. Cells are placed in the extra-capillary space to grow. One or more reservoirs containing cell-culture media and/or an oxygen-containing gas are provided in communication with the at least one fiber. The system is configured to generate alternating flows of both the cell-culture media and the gas through a lumen of the hollow fiber(s), thereby passing both nutrients and gas through the walls of the fiber(s) to the cells in the extra-capillary space to provide a suitable environment for growth and/or proliferation of the cells. Flows of liquid and gas through the hollow fiber(s) can be produced by gravity and/or various pumping configurations.
102	FEEDER-FREE METHOD FOR CULTURE OF BOVINE AND PORCINE SPERMATOGONIAL STEM CELLS	US13763908	2013-02-11	US20130211186A1	2013-08-15	Jon Michael Oatley; Melissa Joan Oatley
The present invention relates to the production and culture of undifferentiated spermatogonial stem cells that can be maintained long term and are feeder free. The resultant feeder-free populations can be used in any of a number of protocols including the generation of progeny bulls. The present invention includes novel methods required for the successful enrichment of bovine spermatogonial stem cells, novel cell lines and other components used for the same, as well as the resultant stem cell compositions.
103	MICROFLUIDIC HANGING DROP CHIP	US13627213	2012-09-26	US20130084634A1	2013-04-04	Chia-Hsien Hsu; Chih-Chen Chen
A microfluidic hanging drop chip is disclosed. Also disclosed are methods for culturing cells and forming cell aggregates in hanging drops.
104	Concentrator Filter	US13149856	2011-05-31	US20110290745A1	2011-12-01	Sarfaraz K. Niazi
A method and an apparatus for separating suspended matter from liquid includes a concentrator filter that draws the liquid out of the suspension while the filter kept unblocked by a sparging filter that allows scrubbing of the concentrator filter by gas bubbles. This invention can be used to replace cross-flow filtration and centrifugation in the bioprocess industry and to reduce the volume of suspensions to concentrate the yield of the end product in the chemical industry.
105	PROCESS FOR CONTROLLING THE PH AND LEVEL OF TARGET IONS OF A LIQUID COMPOSITION	US13062772	2009-09-04	US20110215000A1	2011-09-08	Arvid Garde; Jens-Ulrik Rype
A process for controlling the pH and level of target ions of a liquid composition, more particularly the use of Reverse Electro-Enhanced Dialysis (REED) for extraction of low-molecular, charged species generated in a reactor. Even more particularly the invention relates to a process for pH control and control of inhibitors in bioreactors.
106	Ensiling Biomass For Biofuels Production And Multiple Phase Apparatus For Hydrolyzation Of Ensiled Biomass	US12633555	2009-12-08	US20100144001A1	2010-06-10	Jerry Wayne Horton
A method, apparatus and system for the hydrolyzation of ensiled biomass is disclosed. Ensiled biomass is processed in multiple phases, resulting in a liquid precursor hydrozate and a solid precursor hydrozate. The liquid precursor having significant economic value, and being suitable for uses such as, for example, lower cost and improved efficiency ethanol production. A method for lower cost, improved efficiency alcohol production that uses the resulting liquid precursor hydrozate being produced at distributed sources is further disclosed.
107	Article for growing cultures in a body cavity in the presence of gas, and package for the article	US698470	1976-06-18	US4104127A	1978-08-01	Louis Bucalo
Cultures of microorganisms can be grown in a body cavity by situating therein a nutrient on a suitable carrier while maintaining the nutrient exposed to a predetermined gaseous atmosphere, so that microorganisms which require a particular atmosphere can grow directly in the body cavity on the nutrient. After a time sufficient for culture growth the carrier with the nutrient thereon are removed from the body cavity and inspected, for example, under a microscope with suitable dyes being used to stain the growth for rendering the latter easily visible. The carrier for the nutrient may take the form of a plastic sheet material having small protuberances which are thicker than a nutrient layer carried by the plastic sheet material and which serve to maintain apart from each other surfaces of the plastic and nutrient which otherwise might engage each other to prevent exposure of the nutrient to the predetermined atmosphere. The article is preferably packaged in a container which has in its interior sufficient moisture to prevent drying of the nutrient, the interior of the container being closed off from the outer atmosphere by the sheet material which is used for the container.
108	MICROFLUIDIC HANGING DROP CHIP	PCT/US2012057286	2012-09-26	WO2013049165A8	2014-01-23	HSU CHIA-HSIEN; CHEN CHIH-CHEN
A microfluidic hanging drop chip is disclosed. Also disclosed are methods for culturing cells and forming cell aggregates in hanging drops.
109	METHODS AND DEVICES FOR SAMPLE LYSIS	PCT/US2013061063	2013-09-20	WO2014047523A3	2014-06-26	NJOROGE SAMUEL; GORMAN JOHN; MALTEZOS GEORGE; SCHERER AXEL
Disclosed herein are methods and systems for use in preparing a sample. The methods and systems may be used for lysing one or more structures in a sample (e.g., cells, viral particles, etc.). The methods and compositions may comprise a microfluidic chip or use thereof. The microfluidic chips disclosed herein may comprise (a) a substrate comprising a chamber, wherein at least one mechanical element may be located within the chamber; (b) a thermal element in contact with the chamber; and (c) at least one aperture within the surface of the substrate, wherein the aperture may be configured to insulate the chamber.
110	CONCENTRATOR FILTER	PCT/US2012039109	2012-05-23	WO2012149582A2	2012-11-01	NIAZI SARFARAZ K
A method and an apparatus for separating suspended matter from liquid includes a concentrator filter that draws the liquid out of the suspension while the filter kept unblocked by a sparging filter that allows scrubbing of the concentrator filter by gas bubbles. This invention can be used to replace cross-flow filtration and centrifugation in the bioprocess industry and to reduce the volume of suspensions to concentrate the yield of the end product in the chemical industry.
111	AUTOMATED CELL CULTURE SYSTEM	PCT/CH2011000088	2011-04-20	WO2011130865A3	2012-03-15	LARCHER YVES; HAGG RUPERT
The automated cell culture arrangement according to the invention comprises at least one closed cell culture module with at least one bioreactor. The closed cell culture module is a closed system, which means that within the closed cell culture module a closed sterile environment can be maintained. The automated cell culture arrangement according to the invention, further comprises at least one pump for pumping liquids within the closed cell culture module and at least one additional tool module, which is configured or configurable to act upon or to monitor the contents of a bioreactor and is movable relative to the at least one closed cell culture module or it is movable relative to one or several components of the at least one closed cell culture module.
112	세포배양기	KR1020150032145	2015-03-09	KR1020160108844A	2016-09-21	김두현
세포배양기가개시된다. 본발명의실시예에따른세포배양기는담체가수용된베드를배양조내에서임의로가동되도록하여세포의특성에적합한배양환경이제공되도록함으로써세포의증식률이증가되도록할 수있으며, 세포의배양이완료된후 담체에적절한압력, 원심력및 진동을가하여배양된세포가담체로부터용이하게분리될수 있게함으로써배양된세포의수득률이향상되도록할 수있다.
113	미세 조류를 이용한 수 정화 장치	KR1020167023408	2015-05-22	KR1020160105920A	2016-09-07	강동한; 장영호; 문희천; 김미정; 이기종; 오조교; 이정복; 이수문; 유재인
미세조류에의해생성된광합성산소를호기성미생물이이용하여물을정화하는동시에고순도의조류를생산할수 있는수 정화장치를제공한다. 수정화장치는 I) 오염수가유입되고, 광이조사되는광합성반응부, ii) 광합성반응부내에경사지게설치되고, 상호이격된복수의조류부착망들, iii) 광합성반응부아래에위치하고, 광합성반응부에서생성되는산소를이용해오염수의질산화반응을유도하는호기성미생물이부착된복수의담체들을수용하고, 질산화된액체를생성하는질산화부, iv) 복수의담체들의아래에위치하고, 질산화부에추가로산소를공급하도록적용된산기부, 및 v) 광합성반응부와연결되어복수의조류부착망들로부터탈리된조류를수집하는조류수집부를포함한다.
114	미세조류의 이산화탄소 저장을 위한 가정용 어항 녹조 광 배양기.	KR1020150021024	2015-02-11	KR1020160098864A	2016-08-19	김현호
기존의사진및 그림을걸어두는액자에서는단순한미관추구만이이루어졌다. 이를탈피해액자의케이스를어항으로, 더나아가녹조류가담긴어항으로만듦으로써일반적인어항의형태에서벗어나는데에초점이맞춰졌는데, 녹조류의경우미관상의아름다움은물론이고광합성의효율이뛰어나기때문에이산화탄소를흡수하고산소를방출하여방 안의탁한공기를막게만들어주는효과를가질수 있다. 따라서, 본특허를통해미적인추구는물론이고녹조류의광합성을통하여공기정화능력까지갖추게되었다.
115	곰팡이 발생 억제용 발효식품 저장용기	KR1020140130766	2014-09-30	KR1020160038255A	2016-04-07	고금녀; 이학선; 강지훈; 강성기
본발명은곰팡이발생억제용발효식품저장용기에관한것으로발효식품을저장하는용기에저장된발효식품의곰팡이의생성을억제하기위해용기상부에천일염등과같은소금, 난각또는숯과같은곰팡이억제물질을수용하면서공기이동구가형성된수용부재를구비하여용기내 또는저장된발효식품상부에직접접촉하도록하여용기내의빈 공간에수용된공기또는발효식품에서발생되는가스등에의해곰팡이가발생되는것을억제하도록하는저장용기로서, 발효식품을저장하는본체와상기본체의상부를선택적으로개폐시키는커버부로이루어지는발효식품저장용기에있어서, 상기본체와대응되는구조를가지면서본체내부에저장된발효식품상면에면접또는발효식품상부에들뜬상태로구비되도록상면에상부가개방되며밀폐된하부가하향으로돌출되면서내부에공간을가지는이격된다수개의수용홈이형성되며, 상기수용홈측부에상부및 하부가관통되면서하부가하향으로돌출되는이격된다수개의공기통구가형성되는제1수용부재가구비되고, 상기제1수용부재상면에부착되면서공기이동이자유로운부직포의막재가구비되고, 상기막재가커버된제1수용부재상부에적층되도록내부에공기가충진된밀폐형의쿠션팩이구비되는곰팡이발생억제용발효식품저장용기를제공한다.
116	미생물을 이용한 음식물쓰레기 소멸처리장치	KR1020130138677	2013-11-14	KR1020150056010A	2015-05-22	이현석
본발명은음식물쓰레기를분해, 소멸시키며정화시설을필요로하지않는미생물을이용한음식물쓰레기처리기에있어서처리기상단에음식물투입구가설치되고투입구하단에는디스포저가설치되고연결파이프를통해회전드럼을연결하여회전드럼에배출액을배출시키는배출파이프가연결되며회전드럼은음식물쓰레기를분해하는미생물, 미생물이착상되어있는톨루마린, 회전드럼을유지하는하우징으로이루어지는것을특징으로하는음식물쓰레기처리기를제공할수 있다.
117	미생물 연료전지를 이용한 음식물 쓰레기 처리용 탈수건조기	KR1020130138030	2013-11-14	KR1020150055722A	2015-05-22	장세진
본발명은음식물쓰레기의수분을원심분리방식으로탈수시키고온열로건조를시킨뒤 분쇄처리를한 음식물쓰레기와미생물을혼합, 발효시켜얻은에탄올을가열하여발생하는에너지를전지에저장하고, 저장한에너지로온열건조시키는히터를가동할수 있도록재사용하기위한것이다. 구조가간단하여내구성을높일수 있음은물론작업성과작업능률의향상을꾀할수 있고더 나아가서는생산성향상과아울러제조원가를대폭절감시킬수 있도록한 것이며, 이로인해제품의품질과신뢰성을대폭향상시킬수 있도록한 것이다.
118	음식물 쓰레기 처리기	KR2020140008609	2014-11-24	KR2020150000884U	2015-03-02	김춘재
본고안은음식물쓰레기처리기에관한것이다. 본고안에의한음식물쓰레기처리기의실시예의일 양태는, 외관을정의하는케이싱; 상기케이싱의내부에위치되고, 미생물에의한음식물쓰레기의발효및 분해가이루어지는처리조; 상기처리조에서음식물쓰레기의발효및 분해가이루어지는과정에서발생되는악취를포함하는공기를전달받고, 공기중의악취가오존에의하여제거되는탈취챔버; 및상기탈취챔버에서악취를제거하는과정에서발생되는오존을포함하는공기를전달받고, 공기중의오존을산소로분해하는오존분해챔버; 를포함하고, 상기오존분해챔버의적어도일면에는, 상기오존분해챔버의내부로공기를흡입하기위한다수개의통기공이형성되고, 상기통기공의내주연에서상기오존분해챔버의내부로연장되어상기통기공을통하여상기오존분해챔버의내부로흡입되는공기를이에인접하여위치되는상기오존분해촉매로안내하고, 상기통기공을통하여상기오존분해촉매가상기오존분해챔버의외부로배출되는현상을방지하는다수개의가이드보스를더 포함할수 있다.
119	접착 세포용 배양 용기, 및 접착 세포용 배양 용기의 제조 방법	KR1020137007966	2011-10-04	KR101484867B1	2015-01-20	토타니타카히코; 이시자키요이치; 타나카사토시; 스에나가료; 오타쿄헤이; 쿠니노리마사히로
접착 세포를 배양하는 것이 가능한 배양백을, 필요이상으로 청정도가 높은 제조 환경이나 마스킹과 같은 복잡한 제조 공정을 필요로 하지 않고 제공하는 것을 가능하게 한다. 폴리오레핀으로 이루어지는 접착 세포용 배양 용기이며, 배양 용기의 내면의 일부 또는 전부에 있어서의 정적 수접촉각이 95°이상이며, 한편 물활락시의 히스테리시스가, 전진 접촉각-후퇴 접촉각＞25°를 만족하는 배양 용기로 한다. 이 폴리오레핀에는 산화 방지제를 함유시키는 것이 바람직하고, 특히 페놀계 산화 방지제가 바람직하다. 이러한 접촉각 및 히스테리시스를 나타내는 배양면을 갖춘 접착 세포용 배양 용기는, 폴리오레핀에 대해서 오존 파장을 제외한 자외선을 조사하므로써 얻을 수 있다.
120	조골세포 분화 촉진용 바이오리액터 시스템 및 이를 이용한 조골세포 배양 방법	KR1020130109273	2013-09-11	KR101465362B1	2014-11-25	김근형; 진규현
본 발명은 조골세포 분화 촉진용 바이오리액터 시스템 및 이를 이용한 조골세포 배양 방법에 관한 것이다. 본 발명의 조골세포 분화 촉진용 바이오리액터 시스템에 따르면, 세포담체가 다양한 합성 고분자로 이루어지고 3차원 형태를 가질 뿐만 아니라 특정 범위의 공극크기와 공극률을 가짐으로써, 조골세포의 증식과 분화를 촉진시킬 수 있고, 세포 배양 용기에 구비된 전극을 통해 전기장 공급부에서 발생된 특정 범위의 세기(strength)와 진동수(frequency)를 갖는 정현파 교류가 세포담체에 인가됨으로써 ALP 활성과 칼슘증착(calcium deposition)이 증가되어 그 결과, 골 강화가 유의적으로 증가될 수 있는바, 조골세포의 체외 또는 체내 성장을 최적의 환경을 제공하는 효과가 있다.

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