子分类：
| 序号 | 专利名 | 申请号 | 申请日 | 公开（公告）号 | 公开（公告）日 | 发明人 |
|---|---|---|---|---|---|---|
| 101 | Substituted aromatic compounds | US308805 | 1981-10-05 | US4486354A | 1984-12-04 | Martin G. Baxter; Albert R. Elphick; Alistair A. Miller; David A. Sawyer |
| The present invention provides compounds of the formula (III): ##STR1## or an acid addition salt thereof, wherein R.sup.6 is chlorine, bromine, iodine, C.sub.1-4 alkyl or trifluoromethyl, or R.sup.6 and R.sup.7 form a --CH.dbd.CH--CH.dbd.CH--group optionally substituted by a halogen atom or a C.sub.1-4 alkyl or trifluoromethyl group, R.sup.8 is hydrogen, bromine, iodine, C.sub.1-4 alkyl or trifluoromethyl, R.sup.9 is hydrogen, halogen, C.sub.1-4 alkyl or trifluoromethyl, R.sup.10 is hydrogen, methyl or fluorine and R.sup.11 is amino, C.sub.1-10 acylamino or di-substituted aminomethyleneamino provided that, at most, only two of R.sup.7 -R.sup.10 are other than hydrogen and that R.sup.7 -R.sup.10 are not all hydrogen when R.sup.6 is chlorine. Also provided are pharmaceutical compositions containing compounds of the formula (III), the first medical use of compounds of the formula (III), a process for preparing such compounds and intermediates through which this process proceeds. | ||||||
| 102 | Method for utilizing tetrahydro-4-imino-1-naphthylureas as growth promoting agents for animals | US781231 | 1977-03-25 | US4088786A | 1978-05-09 | Goro Asato; Terence J. Bentley |
| There are provided certain substituted-1,2,3,4-tetrahydro-4-imino-1-naphthylureas, methods of preparation thereof, and methods of use of said naphthylureas for enhancing feed efficiency and for promoting the growth rate of veterinary homothermic animals. | ||||||
| 103 | Tetrahydro-4-imino-1-naphthylureas | US705313 | 1976-07-14 | US4041070A | 1977-08-09 | Goro Asato; Terence James Bentley |
| There are provided certain substituted-1,2,3,4-tetrahydro-4-imino-1-naphthylureas, methods of preparation thereof, and methods of use of said naphthylureas for enhancing feed efficiency and for promoting the growth rate of veterinary homothermic animals. | ||||||
| 104 | Semicarbazones of naphthaldehydes and 5h benzocycloheptene-8-carboxaldehydes | US25787763 | 1963-02-12 | US3139458A | 1964-06-30 | PAQUETTE LEO A |
| 105 | GAS-GENERATING AGENT, AND PROCESS FOR PRODUCING FOAMED OBJECT USING SAME | EP16783059.5 | 2016-04-12 | EP3196271A1 | 2017-07-26 | SAKAI, Haruka; KAGEYAMA, Takuya; UERA, Kazuyoshi; IWATA, Tomoki; YASUDA, Yuji; NAKATA, Kazuya; IWASAKI, Hiroshi; KASUGA, Mitsuru |
The gas generating agent of the present invention comprises a compound represented by general formula (1) below.
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| 106 | Fungicidal phenoxyphenylhydrazine derivatives | EP11160386.6 | 2004-05-25 | EP2385037A1 | 2011-11-09 | Chee, Gaik-Lean; Dekeyser, Mark, A.; Seebold, Kenneth, W., jun.; Osika, Ewa, Maria; Brouwer, Walter, G.; Park, Sheldon, B.; Lai, Hoi, Kiong |
The present invention discloses a fungicidally active compound of the formula:
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| 107 | COMPOSITION A BASE DE DERIVES DE 1,3-DIPHENYLPROP-2-EN-1-ONE SUBSTITUES, PREPARATIONS ET UTILISATIONS | EP03762750.2 | 2003-07-08 | EP1519908B1 | 2007-06-13 | NAJIB, Jamila; CAUMONT-BERTRAND, Karine |
| The invention concerns compositions comprising substituted 1,3-diphenylprop-2-en-1-one derivatives designed for therapeutic use. The inventive compositions are useful in particular for preventing or treating cardiovascular diseases, syndrome X, restenosis, diabetes, obesity, hypertension, inflammatory diseases, cancers or neoplasms (benign or malignant tumors), neurodegenerative, dermatological diseases and disorders related to oxidative stress and for example skin ageing, in particular in the field of cosmetics (occurrence of wrinkles and the like). | ||||||
| 108 | SUBSTITUTED CYCLOPENTANE COMPOUNDS USEFUL AS NEURAMINIDASE INHIBITORS | EP97931014.1 | 1997-06-13 | EP0933993B1 | 2006-04-05 | BABU, Yarlagadda, S.; CHAND, Pooran; MONTGOMERY, John, A. |
| Compounds represented by formula (I), and pharmaceutically acceptacle salts thereof; and their method of preparation are provided. Compounds of the above formula are influenza virus neuraminidase inhibitors and can be used in treating patients infected with influenza virus. | ||||||
| 109 | DERIVES DE 1,3-DIPHENYLPROP-2-EN-1-ONE SUBSTITUES, PREPARATION ET UTILISATIONS | EP03762749.4 | 2003-07-08 | EP1525177A1 | 2005-04-27 | NAJIB, Jamila; CAUMONT-BERTRAND, Karine |
| The invention concerns novel substituted 1,3-diphenylprop-2-en-1-one derivatives, pharmaceutical compositions comprising same, their therapeutic uses, in particular for treating cerebral ischemia. The invention also concerns a method for preparing said derivatives. | ||||||
| 110 | Insecticidal N'-substituted-N,N'-diacylhydrazines | EP86308068.5 | 1986-10-17 | EP0236618B1 | 1991-02-27 | Hsu, Adam Chi-Tung; Aller, Harold Ernest |
| 111 | VERFAHREN ZUR SPEICHERUNG VON ENERGIE IN FORM VON HYDRAZINCARBONAT | EP17787315.5 | 2017-09-22 | EP3544928B1 | 2021-01-06 | HOLWEGER, Walter; WEGENER, Moritz; MUSAYEV, Yashar |
| 112 | VERFAHREN ZUR SPEICHERUNG VON ENERGIE IN FORM VON HYDRAZINCARBONAT | EP17787315.5 | 2017-09-22 | EP3544928A1 | 2019-10-02 | HOLWEGER, Walter; WEGENER, Moritz; MUSAYEV, Yashar |
| 113 | COMPOSITION A BASE DE DERIVES DE 1,3-DIPHENYLPROP-2-EN-1-ONE SUBSTITUES, PREPARATION ET UTILISATIONS | EP03762750.2 | 2003-07-08 | EP1519908A2 | 2005-04-06 | NAJIB, Jamila; CAUMONT-BERTRAND, Karine |
| The invention concerns compositions comprising substituted 1,3-diphenylprop-2-en-1-one derivatives designed for therapeutic use. The inventive compositions are useful in particular for preventing or treating cardiovascular diseases, syndrome X, restenosis, diabetes, obesity, hypertension, inflammatory diseases, cancers or neoplasms (benign or malignant tumors), neurodegenerative, dermatological diseases and disorders related to oxidative stress and for example skin ageing, in particular in the field of cosmetics (occurrence of wrinkles and the like). | ||||||
| 114 | FLUOROUS TAGGING COMPOUNDS AND THEIR USE | EP01932970.5 | 2001-05-03 | EP1280765A2 | 2003-02-05 | CURRAN, Dennis, P.; READ, Roger; LUO, Zhiyong |
| A method of increasing the fluorous nature of a compound includes the step of reacting the compound with at least one second compound having formula (I) wherein Rf is a fluorous group, Rs is a spacer group, d is 1 or 0, m is 1, 2 or 3, Ra is an alkyl group and X is a suitable leaving group. A compound has formula (II) wherein Rf is a fluorous group, n is an integer between 0 and 6, m is 1, 2 or 3, Ra is an alkyl group and X is a leaving group. | ||||||
| 115 | Nouveaux composés azoîques, utilisation pour la teinture, compositions les contenant et procédés de teinture. | EP98402751.6 | 1998-11-05 | EP0918053B1 | 2000-05-10 | Henrion, Jean-Christophe; Philippe, Michel |
| 116 | Cephalosporins, process for their preparation, intermediates and pharmaceutical compositions | EP89304531.0 | 1989-05-05 | EP0341910B1 | 1994-11-23 | Acton, David Gordon; Davies, David Huw; Poyser, Jeffrey Philip |
| 117 | Cephalosporins, process for their preparation, intermediates and pharmaceutical compositions | EP89304531.0 | 1989-05-05 | EP0341910A3 | 1991-05-15 | Acton, David Gordon; Davies, David Huw; Poyser, Jeffrey Philip |
Cephalosporin antibiotics having a 3-position substituent of the formula:
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| 118 | Cephalosporins, process for their preparation, intermediates and pharmaceutical compositions | EP89304531.0 | 1989-05-05 | EP0341910A2 | 1989-11-15 | Acton, David Gordon; Davies, David Huw; Poyser, Jeffrey Philip |
Cephalosporin antibiotics having a 3-position substituent of the formula:
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| 119 | Insecticidal N'-substituted-N,N'-diacylhydrazines | EP86308068.5 | 1986-10-17 | EP0236618A2 | 1987-09-16 | Hsu, Adam Chi-Tung; Aller, Harold Ernest |
This invention is concerned with insecticidal compositions containing N'-substituted-N,N'-diacylhydrazines, methods of using such compositions and with certain of the insecticidal N'-substituted-N,N'-diacylhydrazines which are novel compounds. |
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| 120 | TW107139773 | 2018-11-09 | TW201922690A | 2019-06-16 | CHEN CHING-SHIH; WU CHIA-HSIEN; HSIEH I-SHAN; HUANG PO-HSIEN | |
| The present disclosure provides compounds of Formula (I), and pharmaceutically acceptable salts thereof. The compounds described herein are useful in treating diseases associated with the binding of CREB to CREB-binding protein (CBP) and/or the CREB-CBP pathway, (e.g., proliferative diseases, for example, cancer (e.g., lung cancer or breast cancer), and inflammatory disease (e.g., pancreatic fibrosis or liver fibrosis)). Also provided in the present disclosure are pharmaceutical compositions, kits, methods, and uses including or using a compound described herein. | ||||||
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