| 序号 | 专利名 | 申请号 | 申请日 | 公开（公告）号 | 公开（公告）日 | 发明人 |
|---|---|---|---|---|---|---|
| 141 | METAL OXIDE CATALYSTS FOR ETHERIFICATION, METHOD FOR ITS PREPARATION THEREOF, AND METHOD FOR THE PRODUCTION OF LINEAR POLYGLYCEROL USING THE SAME | PCT/KR2009002948 | 2009-06-03 | WO2010044531A3 | 2010-06-17 | HAN YOO HAN; KIM HYUNG ROK; HAN IN SUN; CHOI HYUN OUNG; KIM HYUN SIC; AN SO YOUNG; YOUN YOUNG HO |
| The present invention relates to a metal oxide catalyst represented by the following Formula 1, which is useful for the production of linear polyglycerol via etherification of glycerol, and a method for its preparation thereof: [Formula 1] (CaO)a?Ca12Al14O33)100-a wherein a refers to a weight ratio of CaO based on 100 parts by weight of the total catalyst. When the alkaline binary metal oxide catalyst according to the present invention is used in the glycerol etherification, it can produce a large amount of linear polyglycerol glycerol. Therefore, the metal oxide catalyst prepared according to the present invention can be effectively used in the production of polyglycerol suitable as cosmetic or food additives. | ||||||
| 142 | EARLY INTERVENTION OF VIRAL INFECTIONS WITH IMMUNE ACTIVATORS | PCT/US2008/007529 | 2008-06-18 | WO2008156753A1 | 2008-12-24 | CARTER, William, A.; STRAYER, David |
Symptoms of viral infection are mitigated by administering to a subject exposed to a virus a protective or symptom-mitigating amount of a dsRNA and continuing administration until the subject's symptoms have improved. |
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| 143 | METHOD FOR MANUFACTURING NEURAMINIC ACID DERIVATIVES | PCT/JP2008057557 | 2008-04-11 | WO2008126943A2 | 2008-10-23 | NAKAMURA YOSHITAKA; MURAKAMI MASAYUKI; YAMAOKA MAKOTO; WAKAYAMA MASAKAZU; UMEO KAZUHIRO |
| A method for manufacturing neuraminic acid derivatives is provided, also synthetic intermediates of the neuraminic acid derivatives and methods for their manufacture, and neuraminic acid derivatives having high purity. [Means for solution] A synthetic intermediate compound represented by the formula (7) is provided: [wherein R3 represents alkyl; R4 and R5 each represents H, alkyl, phenyl, or together represent tetramethylene, pentamethylene, oxo]. | ||||||
| 144 | TRANSITION METAL CATALYZED CROSS-COUPLING OF 1-HALO-1-HALOALKENE COMPOUNDS | PCT/US2006030919 | 2006-08-09 | WO2007021693A8 | 2008-04-10 | GUILES JOSEPH W; QIU JIAN; TARASOW THEODORE M |
| Methods for introducing a 1-halo-l-haloalkene compound onto an aromatic or heteroaromatic ring are provided, including processes for the production of certain 1-halovinyl aryl or heteroaryl derivatives in which the 1-halovinyl group is either 1-fluoro or 1-chlorovinyl and the aromatic species phenyl or thiophene, the processes including coupling an arylmagnesium species with a dihalo olefin in the presence of a nickel or iron catalyst. | ||||||
| 145 | PREPARATION OF SEVOFLURANE WITH NEGLIGIBLE WATER CONTENT | PCT/US2006014427 | 2006-04-18 | WO2006113636A3 | 2007-01-18 | TERRELL ROSS C; LEVINSON JOSHUA A; MCNEIRNEY JOHN C |
| Provided is a sevoflurane anesthetic product which can remain substantially undegraded after long periods of storage, as well as a method for preparing the product. The product comprises sevoflurane in a glass container having a water content of less than 130 ppm. The method comprises drying sevoflurane having a water content of greater than 130 ppm to a water content les than 130 ppm. A preferred method of drying comprises contacting a sevoflurane composition having a water content of greater than 130 ppm with alumina-containing molecular sieves such that the water content is reduced to less than 130 ppm. | ||||||
| 146 | スルホナート触媒及びそれを利用したアルコール化合物の製法 | PCT/JP2006/304750 | 2006-03-10 | WO2006137195A1 | 2006-12-28 | 内海 典之; 村田 邦彦; 堤 邦彦; 片山 武昭; 渡辺 正人; 大熊 毅; 野依 良治 |
| The sulfonate catalyst represented by the following formula and a ketone compound are added to a solvent and the ingredients are mixed together in the presence of hydrogen. Thus, the ketone compound is hydrogenated to produce an optically active alcohol. | ||||||
| 147 | TUBULIN BINDING AGENTS AND CORRESPONDING PRODRUG CONSTRUCTS | PCT/US2004/009417 | 2004-03-26 | WO2004087061A3 | 2004-10-14 | PINNEY, Kevin, G.; MOCHARLA, Vani, P.; CHEN, Zhi; GARNER, Charles, M.; GHATAK, Anjan; HADIMANI, Mallinath; KESSLER, Jimmy; DORSEY, James, M.; EDVARDSON, Klaus; CHAPLIN, David, J.; PREZIOSO, Joseph; JELINEK, Christopher |
A diverse set of tubulin binding agents have been discovered which are structurally characterized, in a general sense, by a semi-rigid molecular framework capable of maintaining aryl-aryl, pseudo pi stacking distances appropriate for molecular recognition of tubulin. In phenolic or amino form, these ligands may be further functionalized to prepare phosphate esters, phosphate salts, phosphoramidates, and other prodrugs capable of demonstrating selective targeting and destruction of tumor cell vasculature. |
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| 148 | DEVICES AND METHODS FOR ELIMINATING TERMITE COLONIES | PCT/US2003/017714 | 2003-06-05 | WO2003106395A1 | 2003-12-24 | BRODE, Philip, F., III; GARRETT, Gary, S.; LAUGHLIN, Leo, T. |
This invention relates to devices, kits, and methods for eliminating termite colonies. The kits, devices, and methods employ a termiticidal bait matrix containing a) a termiticide selected such that the termiticide causes death to about 50 to about 100% of termites within about 24 to about 84 days after the termites begin to ingest the termiticide or the bait matrix comprising the termiticide, b) a cellulose containing material, and c) water. The termiticidal bait matrix can be used in a bait station installed in the ground. The kits are suitable to be used by consumers in their homes. |
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| 149 | CATLAYTIC BORONATE ESTER SYNTHESIS FROM BORON REAGENTS AND HYDROCARBONS | PCT/US0223302 | 2002-07-13 | WO03006158A3 | 2003-04-03 | SMITH MILTON R III |
| A process for producing a ring-substituted arene borane which comprises reacting a ring-substituted arene with an HB organic compound in the presence of a catalytically effective amount of an iridium or rhodium complex with three or more substituents, excluding hydrogen, bonded to the iridium or rhodium and a phosphorus organic ligand, which is at least in part bonded to the iridium or rhodium, to form the ring-substituted arene borane. Also provided are catalytic compounds for catalyzing the process comprising an iridium or rhodium complex with three or substituents, excluding hydrogen, bonded to the iridium or rhodium and optionally, a phosphorus organic ligand, which is at least in part bonded to the iridium or rhodium. | ||||||
| 150 | INTEGRATED PROCESS FOR SYNTHESIZING ALCOHOLS AND ETHERS FROM ALKANES | PCT/US2002/018775 | 2002-06-13 | WO2003000635A1 | 2003-01-03 | ZHOU, Xiao, Ping; LORKOVIC, Ivan, Marc; STUCKY, Galen, D.; FORD, Peter, C.; SHERMAN, Jeffrey, H.; GROSSO, Philip |
Alcohols and/or ethers are synthesized from alkanes by mixing an alkane and bromine in a reactor to form alkyl bromide and hydrogen bromide. The alkyl bromide is directed into contact with metal oxide to form alcohol and/or ether and a metal bromide. The metal bromide is oxidized to metal oxide and bromine, both of which are recycled. |
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| 151 | METHOD FOR PRODUCING BENZYL DERIVATIVES OF 2-BUTENE-1,4 DIOLS | PCT/GB2001/004036 | 2001-09-10 | WO02022537A2 | 2002-03-21 | |
| A method for producing benzyl derivatives of 2-butene-1,4-diols by reacting 2-butene-1,4-diols with benzyl chloride compounds in the presence of an alkali or alkaline earth metal hydroxide or carbonate to produce benzyl derivatives of 2-butene-1,4-diols and recovering at least a portion of at least one such benzene derivative. | ||||||
| 152 | PROCESS FOR PREPARING ALKOXY OR ARYLMETHOXY AROXYETHANES | PCT/US2001/003328 | 2001-02-01 | WO01060775A1 | 2001-08-23 | |
| The present invention is a novel process, with or without solvent, for manufacture of compounds of formula (a), wherein P is selected from phenyl and naphthyl; wherein R1 and R2 and R3 are each independently selected from hydrogen, alykl, alkoxy, aryl, aralkyl, aralkoxy, halogen, alkoxyalkoxy, and aralkoxyalkoxy; wherein R5 is selected from substituted or unsubstituted phenyl, and substituted or unsubstituted naphthyl, the substituents being each independently selected from alkyl (C1-C8), alkoxy (C1-C8), aroxy, aralkoxy (C1-C8) and halogen. The process comprises reacting substituted phenols or naphthols of the formula (b) with ethylene carbonate in the presence of a first catalyst selected from metal halide, quaternary ammonium halide and quarternary phosphonium halide thereby forming an intermediate of the formula (c), then reacting the intermediate with a first compound selected from alkyl or aralkylhalide, alkyl or aralkyl sulfate, and alkyl or aralkyl sulfonate together with a metal hydroxide in the presence of a second catalyst, the second catalyst selected from quaternary ammonium salt or quaternary phosphonium salt. | ||||||
| 153 | METHOD FOR SYNTHESIZING SEVOFLURANE AND AN INTERMEDIATE THEREOF | PCT/US2000/007801 | 2000-03-24 | WO00058251A1 | 2000-10-05 | |
| A method for synthesizing fluoromethyl-1,1,1,3,3,3-hexafluoroisopropyl ether. The method includes the step of combining in the presence of aluminum trichloride a quantity of hexafluoroisopropanol and a quantity of either 1,3,5-trioxane or paraformaldehyde to produce sevochlorane. The resulting sevochlorane is then combined with an alkali metal fluoride to produce fluoromethyl-1,1,1,3,3,3-hexafluoroisopropyl ether. | ||||||
| 154 | TWO-PHOTON OR HIGHER-ORDER ABSORBING OPTICAL MATERIALS | PCT/US1999/008383 | 1999-04-16 | WO99053242A1 | 1999-10-21 | |
| Disclosed are highly efficient multiphoton absorbing compounds and methods of their use. The compounds generally include a bridge of pi-conjugated bonds connecting electron donating groups or electron accepting groups. The bridge may be substituted with a variety of substituents as well. Solubility, lipophilicity, absorption maxima and other characteristics of the compounds may be tailored by changing the electron donating groups or electron accepting groups, the substituents attached to or the length of the pi-conjugated bridge. Numerous photophysical and photochemical methods are enabled by converting these compounds to electronically excited states upon simultaneous absorption of at least two photons of radiation. The compounds have large two-photon or higher-order absorptivities such that upon absorption, one or more Lewis acidic species, Lewis basic species, radical species or ionic species are formed. | ||||||
| 155 | PREPARATION OF POLYOXYALKYLENE ETHER SURFACTANT COMPOSITIONS | PCT/US1997022174 | 1997-11-28 | WO1998027040A1 | 1998-06-25 | OLIN CORPORATION; SHEN, Ming |
| The present invention is directed to a process for the preparation of polyoxyalkylene ether surfactant compositions comprising the steps of combining an admixture of alkoxylated alcohols with an acid catalyst and 1-6 molar equivalents of an aldehyde. The mixture is reacted at between about 50 DEG C and about 180 DEG C and at between about 1 atm and 10 atm pressure in the absence of a distillation step to produce the polyoxyalkylene ether surfactant composition. | ||||||
| 156 | METHOD FOR THE PREPARATION OF DIALKYL ETHERS | PCT/US1997002768 | 1997-02-25 | WO1997035823A1 | 1997-10-02 | CHEMICAL RESEARCH & LICENSING COMPANY; NEMPHOS, Speros, Peter; HEARN, Dennis |
| A method for producing dialkyl ethers comprising feeding a stream containing a C1 to C4 alcohol to a distillation column reactor into a feed zone, contacting the stream with a fixed bed zeolite prepared as a distillation structure to form the corresponding dialkyl ether and water, and concurrently fractionating the ether product from the water and unreacted materials, wherein the improvement is the addition of a small amount of hydrogen to the reaction zone to inhibit catalyst fouling and substantially increasing the catalyst life and activity. | ||||||
| 157 | PROCESS FOR THE PRODUCTION OF ALKYLENE OR CYCLICALLY LINKED COMPOUNDS | PCT/EP8700527 | 1987-09-16 | WO8802357A3 | 1988-06-16 | POETSCH EIKE; REIFFENRATH VOLKER |
| Compounds having formula (I): R<1>-(A |
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| 158 | HEXASUBSTITUTED CYCLOHEXANE COMPOUNDS | PCT/EP8700318 | 1987-06-19 | WO8800940A2 | 1988-02-11 | PRAEFCKE KLAUS; KOHNE BERND; DORSCH DIETER; RIEGER BERNHARD |
| Hexasubstituted cyclohexane compounds which are suitable as components of discotic liquid crystal phases. | ||||||
| 159 | VINYL COMPOSITIONS | PCT/EP8600754 | 1986-12-16 | WO8704426A3 | 1987-10-22 | WAECHTLER ANDREAS; KRAUSE JOACHIM; EIDENSCHINK RUDOLF; SCHEUBLE BERNHARD; HITTICH REINHARD |
| Vinyl compositions having formula (I): R1-(A1-Z1)m-(A2-Z2)n-(A3)o-Q-CH=CH-R2, in which R1, R2, A1, A2 and A3, Z1 and Z2, m and o, n, Q and p have the definitions given in claim 1, are useful as components of liquid crystal phases. | ||||||
| 160 | NOUVEAUX DERIVES DE D-MANNITE COMME PRODUITS DE DEPART POUR LA SYNTHESE DE PHOSPHOLIPIDES | PCT/DE8300123 | 1983-07-06 | WO8400362A3 | 1984-06-07 | EIBL HANSJOERG |
| The mannite derivatives have the formula (I) wherein R1 and R2, identical or different, represent when they are identical a straight or branched alkyl, alkenyl or alkynyl group containing from 6 to 24 atoms of carbon which may be substituted by a cycloalkyl rest having from 3 to 6 atoms of carbon, an aryl, benzyloxy, allyloxy, mesyloxy rest and/or halogen atoms and when R1 and R2 are different, they represent a straight or branched alkyl group with 1 to 24 atoms of carbon, which may be substituted by a cycloalkyl rest having from 3 to 6 atoms of carbon, an aryl, benzyloxy, allyloxy, mesyloxy rest and/or halogen atoms, with the possibility for R1 of being also a trityl group. From said mannite derivatives, it is possible to obtain in a simple way and with good yields the phospholipids in the form of their optical stereo isomers. | ||||||
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