Pyrazolopyridine compound
专利汇可以提供Pyrazolopyridine compound专利检索，专利查询，专利分析的服务。并且NEW MATERIAL:A compound expressed by formula I [Ar
1 represents (substituted)phenyl or heteroaryl; Ar
2 represents (substituted)phenyl or (substituted)heteroaryl] or acid addition salts thereof.
EXAMPLE: 3-(4-Chlorophenyl)-1-(4,6-dimethyl-2-pyrimidinyl)-1H-pyrazolo[3,4- b]pyridine.
USE: A prophylactic and remedial agent for autoimmune disease, cancer, etc., such as hypoleukocytosis, infectious disease caused by reduction of biophylaxis, allergic disease, lupus erythematosus or chronic rheumarthrities.
PREPARATION: A compound expressed by formula II (X
1 represents halogen such as F
1 Cl or Br) is cyclired with a compound expressed by the formula H
2 NHN-Ar
2 at 50W250°C, preferably in an inert solvent such as benzene using a dehydrating agent, as necessary, to afford a compound expressed by formula III. Subsequently the resultant compound is further cyclized, preferably in an inert solvent such as pyridine, using a deacidifying agent, as necessary, at 50W250°C.
COPYRIGHT: (C)1989,JPO&Japio，下面是Pyrazolopyridine compound专利的具体信息内容。
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