Certain 5-alkyl-3-hydroxyisoxazoles

申请号 US3544584D 申请日 1968-10-01 公开(公告)号 US3544584A 公开(公告)日 1970-12-01
申请人 SANKYO CO; 发明人 IWAI ISSEI; KISHIDA YUKICHI; HIRAOKA TETSUO; NAKAMURA NORIO;
摘要 A process for preparing a compound having the formula WHEREIN R represents hydrogen; alkyl; unsubstituted or substituted phenyl; or dialkoxymethyl of from one to five carbon atoms in each alkoxy moiety, which comprises reacting a compound having the formula R - C 3BOND C - COOR'wherein R is as defined above and R' represents alkyl of from one to five carbon atoms with hydroxylamine in the presence of an alkali metal hydroxide, the alkali metal hydroxide being used in an amount sufficient to maintain the reaction medium at an alkaline pH range.
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